July 2021 PMID 33627329

Hypotension in Preterm Infants (HIP) randomised trial.

Eugene M Dempsey, Keith J Barrington, Neil Marlow, Colm Patrick Finbarr O'Donnell, Jan Miletin, Gunnar Naulaers, Po-Yin Cheung, John David Corcoran, Afif Faisal El-Khuffash, Geraldine B Boylan, Vicki Livingstone, Gerard Pons, Jozef Macko, David Van Laere, Hana Wiedermannova

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Mentions

Peak: 7 in Feb 2021

across 3 sources since Feb 2021

Extended reach

99,663

potential audience

Total likes

769

Video views

27,455

Mentions per month

Feb 2021 – Aug 2025

Where it's discussed

X / Twitter15 posts
YouTube3 videos
Blogs3 articles

AI synopsis

What people are saying

Discussions reflect a tempered interest, with posts such as @DrKlugs mentioning enrollment challenges and the need for more data, indicating awareness of the trial's limitations. Other posts reference the trial directly, using phrases like 'challenging with enrollment' and 'may not help,' which demonstrate a cautious acknowledgment of its implications without strong support or critique, contributing to a balanced overall perspective.

AgreementNeither agree nor disagree

Most discussions acknowledge the trial's findings with mixed reactions, some emphasizing the challenges in data collection, indicating neither strong agreement nor disagreement.

InterestModerate interest

Posts show moderate curiosity, referencing the trial's design, outcomes, and implications but lack deep detail or critique.

EngagementModerate engagement

Comments reflect a basic understanding, sharing summaries and brief interpretations, with some users reflecting on research challenges and clinical relevance.

ImpactModerate impact

While some posts highlight the ongoing debate about treatment strategies for hypotension in preterm infants, the overall tone suggests moderate recognition of its significance rather than revolutionary impact.

Abstract in brief

The study aimed to see if restricting inotrope use after low blood pressure diagnosis in very premature infants affects survival without serious brain injuries, but the trial was stopped early due to recruitment issues.
Infants were randomly assigned to either a standard treatment with dopamine or a restrictive approach with saline and a placebo, and the outcomes showed no significant difference in survival without brain injury between the groups.
Although the trial lacked enough participants to be definitive, it suggests that a restrictive approach to treating low blood pressure in preterm infants may not worsen their clinical outcomes, guiding future research.

Read the full abstract

All mentions

Myths about Newborn Blood Pressure and Hemodynamic Management

Inotropes, vasopressors, and why blood pressure matters in neonates. We discuss what constitutes low blood pressure, the importance of oxygenation, and how to approach treatment in preterm hypotension, emphasizing…

Tala Talks NICU · Apr 15, 2024 16,716 views

Myths and Facts About Neonatal Hypotension and Blood Pressure Management

This video explores common myths about neonatal blood pressure, including cuff accuracy, the use of dopamine and steroids, volume boluses, and when to perform echocardiography to guide treatment.

Tala Talks NICU · May 13, 2024 10,479 views

Neonatal Hypotension: Myths and Evidence-Based Facts

Neonatal hypotension involves misconceptions and facts. This video debunks common myths and presents science-backed information on managing hypotension in neonates, based on current research and clinical experience.

Neonatal Kalp Akademisi · Aug 9, 2025 260 views

Julie Nogee, MD

@JNogMD · X

@DrKlugs Also intervention trials as to whether or not treating "low" helps have had challenges with enrollment - so we will never have all the data to guide decisions in babies. https://t.co/IH62IpsN4n

May 25, 2022 · 945 followers View post →

neo_papers

@neo_papers · X

Hypotension in Preterm Infants (HIP) randomised trial #NeoPapers https://t.co/KrN1SLmUec

Mar 5, 2021 · 5,738 followers View post →

PedsICU_tweets

@PedsICU_tweets · X

RT @PICJournalWatch: Hypotension in Preterm Infants (#HIP) randomised trial #PedsICU #NeoEBM #FOAMneo https://t.co/rKdx4Cmo9D

Mar 4, 2021 · 1 share · 5,477 followers View post →

PICU Journal Watch #PedsICU #PedsCICU

@PICJournalWatch · X

Hypotension in Preterm Infants (#HIP) randomised trial #PedsICU #NeoEBM #FOAMneo https://t.co/rKdx4Cmo9D

Mar 4, 2021 · 1 share · 10,029 followers View post →

neo_papers

@neo_papers · X

Hypotension in Preterm Infants (HIP) randomised trial #NeoPapers https://t.co/qD6jpxc59c

Mar 4, 2021 · 5,738 followers View post →

neo_twiter

@neo_twiter · X

RT @neo_papers: Hypotension in Preterm Infants (HIP) randomised trial #NeoPapers https://t.co/lM0iSBxt1B

Mar 3, 2021 · 1 share · 2,911 followers View post →

neo_papers

@neo_papers · X

Hypotension in Preterm Infants (HIP) randomised trial #NeoPapers https://t.co/lM0iSBxt1B

Mar 3, 2021 · 1 like · 1 share · 5,738 followers View post →

neo_papers

@neo_papers · X

Hypotension in Preterm Infants (HIP) randomised trial #NeoPapers https://t.co/qXLIVJgPGw

Mar 2, 2021 · 5,738 followers View post →

neo_papers

@neo_papers · X

Hypotension in Preterm Infants (HIP) randomised trial #NeoPapers https://t.co/uCr4WZvfQ1

Feb 28, 2021 · 5,738 followers View post →

neo_twiter

@neo_twiter · X

RT @neo_papers: Hypotension in Preterm Infants (HIP) randomised trial #NeoPapers https://t.co/q2usKEdg2c

Feb 27, 2021 · 2 shares · 2,911 followers View post →

Augusta

@AOauggie · X

RT @neo_papers: Hypotension in Preterm Infants (HIP) randomised trial #NeoPapers https://t.co/q2usKEdg2c

Feb 27, 2021 · 2 shares · 1,097 followers View post →

neo_papers

@neo_papers · X

Hypotension in Preterm Infants (HIP) randomised trial #NeoPapers https://t.co/q2usKEdg2c

Feb 27, 2021 · 3 likes · 2 shares · 5,738 followers View post →

neo_papers

@neo_papers · X

Hypotension in Preterm Infants (HIP) randomised trial #NeoPapers https://t.co/xkMxLaGgjg

Feb 26, 2021 · 5,738 followers View post →

neo_twiter

@neo_twiter · X

RT @neo_papers: Hypotension in Preterm Infants (HIP) randomised trial #NeoPapers https://t.co/hyNGooShxU

Feb 25, 2021 · 1 share · 2,911 followers View post →

neo_papers

@neo_papers · X

Hypotension in Preterm Infants (HIP) randomised trial #NeoPapers https://t.co/hyNGooShxU

Feb 25, 2021 · 1 share · 5,738 followers View post →

Hypotension in Preterm Infants (HIP) randomised trial.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Myths about Newborn Blood Pressure and Hemodynamic Management

Myths and Facts About Neonatal Hypotension and Blood Pressure Management

Neonatal Hypotension: Myths and Evidence-Based Facts