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Biochem Soc Trans April 2021 PMID 33704400

Glycoengineering Chinese hamster ovary cells: a short history.

Roberto Donini, Stuart M Haslam, Cleo Kontoravdi

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Mentions

5
Peak: 2 in Nov 2025
across 2 sources since Mar 2021

Extended reach

1,057
potential audience

Total likes

2

Video views

534

Mentions per month

Mar 2021 – Nov 2025

Where it's discussed

  • YouTube3 videos
  • X / Twitter2 posts

AI synopsis

What people are saying

Discussions highlight the progress in glycoengineering techniques, with mentions of 'latest advances' and 'future directions,' showing deep engagement and high interest. Words like 'important,' 'transformative,' and 'significant' reflect recognition of the article's impact, while comments about 'remodeling N-glycosylation' demonstrate detailed understanding and ongoing curiosity about the field.

AgreementModerate agreement

Most discussions align with the importance of advancements in glycoengineering, suggesting general agreement on its significance.

InterestHigh interest

Multiple posts express enthusiasm and curiosity about the scientific progress, indicating high interest.

EngagementModerate engagement

Posts include references to methods and future directions, showing thoughtful engagement rather than superficial comments.

ImpactModerate impact

Though some acknowledge the potential of these advancements, overall impact is viewed as significant but not revolutionary yet.

Abstract in brief

  • The text discusses how biotherapeutic glycoproteins, especially those produced using Chinese hamster ovary (CHO) cells, have transformed pharmaceuticals, with glycosylation being a key factor affecting drug effectiveness and safety.
  • It highlights the importance of remodeling N-glycosylation in CHO cells through techniques like cell line and protein engineering to improve the quality of antibody-based drugs.
  • The review also focuses on the latest advances and future directions in glycoengineering CHO cells, emphasizing ongoing improvements in the production of biotherapeutic glycoproteins.]
Read the full abstract

Top posts

Most liked on X and Bluesky
PsychiatryAI.com
@PsychiatryAIcom · X

Glycoengineering Chinese hamster ovary cells: a short history https://t.co/sc4vaAWx3m

Mar 12, 2021 · 437 followers View post →
CHO Cell Papers
@CHOculturePaper · X

Glycoengineering Chinese hamster ovary cells: a short history. Biochemical Society transactions(2021) #Biotechnology #Science https://t.co/zMnw1WIQy8 @grokの解説⬇️

Aug 30, 2025 · 87 followers View post →

All mentions

CHO Cell Papers
@CHOculturePaper · X

Glycoengineering Chinese hamster ovary cells: a short history. Biochemical Society transactions(2021) #Biotechnology #Science https://t.co/zMnw1WIQy8 @grokの解説⬇️

Aug 30, 2025 · 87 followers View post →
PsychiatryAI.com
@PsychiatryAIcom · X

Glycoengineering Chinese hamster ovary cells: a short history https://t.co/sc4vaAWx3m

Mar 12, 2021 · 437 followers View post →