Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial.
The collection shows a predominantly positive and curious discussion about STEP 4, with many posts highlighting that continuation of semaglutide leads to sustained weight loss while stopping leads to regain. Posts cite the magnitude of effects (e.g., continued weight loss around 7.9% vs regain ~6.9%), and several discuss policy, access, and broader implications. Language ranges from celebratory summaries to cautions about side effects and real-world applicability, reflecting diverse voices but a shared interest in the trial’s implications for obesity treatment and long-term management.
AgreementModerate agreement
Overall leaning toward acknowledging continued semaglutide benefits, with some skeptical or neutral notes in a subset of posts.
InterestHigh interest
High level of interest across languages and regions, frequent citations and calls to data.
EngagementModerate engagement
Many posts quote results or discuss mechanisms, but some are just sharing links or opinions without in-depth analysis.
ImpactModerate impact
Signals of moderate to high impact discussions, especially around continued use and weight regain after stopping.
Abstract in brief
The STEP 4 randomized clinical trial investigated the impact of continuing weekly semaglutide treatment compared to a placebo on weight loss maintenance in adults with overweight or obesity.
The study involved 902 participants and included a 20-week run-in period followed by 48 weeks where participants either continued semaglutide or switched to placebo, both with lifestyle intervention.
Results showed a mean weight loss percentage change from week 20 to week 68 of 7.9% for those continuing semaglutide versus 6.9% for the placebo group, indicating that continued treatment may be beneficial for maintaining weight loss.
Dec 14, 2022 · 104 likes · 13 shares · 12,161 followersView post →
CM
Carlos Morillas
@61Morillas · X
Nuevas evidencias de la eficacia de Semaglutide 2,4 mg en estudio STEP 4. Más cerca de su aprobación para personas con obesidad @sociedadSEEN @SociedadSeedo @SVEDYN_ https://t.co/yF2WdHakMP a través de @JAMA_current part of @JAMANetwork
Mar 27, 2021 · 55 likes · 17 shares · 2,620 followersView post →
SL
Srđan Lukić
@srdjl · X
U prevodu, lek semaglutid je, kao uostalom i sve drugo što je učinkovito u mršavljenju, efikasan samo dok se primenjuje, ima odličan ali vremenski i procentualno ograničen učinak i kada se ukine dolazi do rebound efekta.
Cela studija: https://t.co/BBGPDJcHXM
Feb 26, 2023 · 41 likes · 16,488 followersView post →
JN
Jen Can NuSH
@JCanNuSH · X
https://t.co/i72EVYE71g
Jun 25, 2026 · 34 likes · 5 shares · 1,572 followersView post →
DP
Dr Zoe Harcombe, PhD
@zoeharcombe · X
Refs:
Drugs withdrawn: https://t.co/4mqMKuFbSh
Lawsuits: https://t.co/phY9bYQQiR
& death: https://t.co/pBPiAAO7QE
Blog about Ozempic: https://t.co/eeE8gSGADp
What happens when they're stopped: https://t.co/3D6jdpCnkT
Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial @JAMA_current https://t.co/f78ymCNd0t
Mar 23, 2021 · 31 likes · 10 shares · 3,363 followersView post →
Examines the STEP 4 trial showing continued weekly semaglutide vs placebo after a 20-week run-in, with lifestyle support. From week 20 to 68, weight loss percent change averaged 7.9% vs 6.9%, highlighting potential…
Explores research on patient adherence to GLP-1 obesity medications and the reasons some users discontinue treatment, with expert context and implications for care.
Studies show two-thirds of lost weight can return within a year after stopping injections like semaglutide; discusses implications and cautions for long-term treatment strategies.
Portuguese-language episode covering when to prescribe semaglutide, administration, potential adverse events, and contraindications, with clinical guidance for practitioners.
In this video, we discuss the use of weight-loss injections and their potential to revolutionize obesity treatment versus industry-promoted promises. We examine scientific insights on GLP-1 hormones and recent research…
Explains how semaglutide alters appetite and weight loss, why it lasts a week in blood, common side effects, and what happens after stopping treatment.
This video discusses Ozempic, a medication revolutionizing obesity treatment. We delve into the STEP 4 trial, which examined the effects of weekly semaglutide versus placebo on weight loss maintenance in adults…
A concise look at how most weight returns after stopping GLP-1 receptor agonists, with an exponential regain pattern and a projected plateau near 75% of lost weight based on six RCTs.
What happens to hunger and weight after stopping GLP-1 drugs; the science behind rebound appetite and how dosing strategies may influence long-term outcomes.
Exploring the real-world weight regain after stopping GLP-1 therapies, including key trial findings and the decelerating regain pattern across major studies.
In this episode of The Balanced Bodies Blueprint, we delve into your pressing health questions, including menopause and weight loss strategies. Discover effective ways to maintain results during the holidays and the…
A look at the reasons people consider stopping GLP-1 therapies, including the significant ongoing costs and what the science says about weight regain after withdrawal.
@peptidesgpt Worth adding the RCT anchor: STEP 4 (n=803) — after a 20-wk run-in (~10.6% lost), continuing semaglutide gave another −7.9% by wk 68; switching to placebo gave +6.9% regain. Regain on stopping is expected pharmacology. https://t.co/2s7G0CagSg
9/ And the side effects. Look at this chart. 44% of users report nausea. 30% diarrhea. 24% vomiting. 24% constipation. 20% abdominal pain. Up to 40% of the weight lost on Ozempic is muscle, not fat. That's where "Ozempic face" comes from. You're not just losing fat. You're losing https://t.co/gxDJP8OOpq
Ficha bibliográfica
Rubino D, Abrahamsson N, Davies M, et al. Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity (STEP 4). JAMA. 2021;325(14):1414-1425. doi:10.1001/jama.2021.3224
Jan 9, 2026 · 5 likes · 5,271 followersView post →
DS
Dr Shailesh Singh
@drShaileshSingh · X
All the trials and studies i have talked about
1. Wadden TA, Bailey TS, Billings LK, Davies M, Frias JP, Koroleva A, et al. Effect of subcutaneous semaglutide vs placebo as an adjunct to intensive behavioral therapy on body weight in adults with overweight or obesity: The STEP
Dec 20, 2025 · 4 likes · 9,064 followersView post →
CG
Central Alexisonfire Centro de Guarulhos
@leianesonfire.bsky.social · Bluesky
Eu acompanho alguns canais de divulgação científica e principalmente sobre alimentação e endocrinologia e eu gosto muito da Kamarada Luna, queria mais divulgadores abertamente de esquerda/marxistas youtu.be/egF6hPqPMjY?...
University of Michigan @UMich imposes lifetime limits on #GLP1 access: https://t.co/gQMwxyqYve
Bewildering when a well-respected academic institution implements policy precisely COUNTER to the scientific evidence (https://t.co/lvSjXCXOdX, https://t.co/pIjMlBFHxK)
#obesity https://t.co/0vIlORxiFF
@Davoricus @RandomMHumanoid @KeithMansfield @peterrhague Those switched to placebo after 20 weeks gained most of the weight back. https://t.co/MjlfbJOgoi https://t.co/7FcABzLIrB
معلومة علي الماشي ??
ادويه انقاص الوزن الحديثه ما لها و ما عليها
سيماجلوتايد (Semaglutide):
يُباع تجاريًا باسم Wegovy وOzempic. يستخدم عادة لعلاج مرض السكري من النوع الثاني، لكنه يستخدم أيضًا لفقدان الوزن عن طريق زيادة الشعور بالشبع وتقليل تناول الطعام.
موجنارو (Mounjaro):
•
Oct 22, 2024 · 1 like · 1,152 followersView post →
ЧТ
чё за костёр тут?
@LOOKATSEV · X
@Slide_Gauge @fuck_kgb На самом деле STEP 4 исследования проводили до 68 недель использования, что как бы уже приличный срок. Куда уже больше? А самые первые лекарства вышли на рынок уже больше 10 лет назад, если бы что-то было, то давно вскрыли.
https://t.co/pkkaoJ8EMH
Links Included in Briefing:
Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes:
https://t.co/rqX4giyteM
Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity:
https://t.co/6mmrAYKPp7
Refs:
Drugs withdrawn: https://t.co/4mqMKuFbSh
Lawsuits: https://t.co/phY9bYQQiR
& death: https://t.co/pBPiAAO7QE
Blog about Ozempic: https://t.co/eeE8gSGADp
What happens when they're stopped: https://t.co/3D6jdpCnkT
Session of the day at #ACC24 @ACCinTouch for me was "Balancing the Scale" on anti-obesity drugs. Key point:
Continue after patients reach their goal--similar to how we manage blood pressure and lipids.
#ACCCVT #ACCMember
Rubino, et al. (2021) JAMA doi:10.1001/jama.2021.3224 https://t.co/MRJLilOZWk
@eeagorajose @malu_maderfc ta no material suplementar do STEP1 uma proporção de 41% de perda de massa magra em relação a gordura
800 pacientes que atingiram dose máxima
https://t.co/GXaz6Qy1g8
Mar 26, 2024 · 6 likes · 11,885 followersView post →
@Intimacyenergy @alxoh0lic @danishacarterr Here are a few
https://t.co/AQWo9nAGfi
https://t.co/SUsDaVKU67
https://t.co/xHvkausmEo
https://t.co/6lESN9yIMP
https://t.co/x6GjXPuO7U
Jan 1, 2024 · 5 likes · 1,629 followersView post →
GX
gamechanger2020xz
@gamechanger2022 · X
Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight ... https://t.co/U5ybgj0VJ4
And because drugs alone don't help people change their relationships with food or develop healthy, sustainable dietary patterns, people quickly regain weight as soon as they stop the treatment. 3/5
Jun 12, 2023 · 2 likes · 10,657 followersView post →
KH
Kevin Hall
@KevinH_PhD · X
What happens if instead stopping the intervention people are switched from semaglutide to placebo? This was studied in the STEP 4 trial & simulated below in the dashed curve (those continuing the drug are in solid curves). https://t.co/lC9ygwXEVf https://t.co/9ax1pnPTFu
May 3, 2023 · 20 likes · 1 share · 38,085 followersView post →
BC
Ben Celis
@celis_ben · X
RT @HoeyberghsJeff: Het effect van het nieuwe vermager-medicijn SEMAGLUTIDE is averechts wanneer gestopt en bescheiden wanneer men er mee d…
Mar 11, 2023 · 4 shares · 1,649 followersView post →
KR
Kylo Ren
@ddfa3434 · X
RT @HoeyberghsJeff: Het effect van het nieuwe vermager-medicijn SEMAGLUTIDE is averechts wanneer gestopt en bescheiden wanneer men er mee d…
Mar 10, 2023 · 4 shares · 490 followersView post →
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Nadia
@Naadieake · X
RT @HoeyberghsJeff: Het effect van het nieuwe vermager-medicijn SEMAGLUTIDE is averechts wanneer gestopt en bescheiden wanneer men er mee d…
Mar 10, 2023 · 4 shares · 406 followersView post →
CM
Ceragioli Maxime
@CeragioliMaxime · X
RT @HoeyberghsJeff: Het effect van het nieuwe vermager-medicijn SEMAGLUTIDE is averechts wanneer gestopt en bescheiden wanneer men er mee d…
Het effect van het nieuwe vermager-medicijn SEMAGLUTIDE is averechts wanneer gestopt en bescheiden wanneer men er mee doorgaat. "With continued semaglutide, mean body weight change from week 20 to week 68 was −7.9% vs +6.9% with the switch to placebo"
https://t.co/TmyX1qNSQT
Mar 9, 2023 · 7 likes · 4 shares · 25,062 followersView post →
JE
Jacob Eliosoff
@JaEsf · X
@AlecStapp This is my favorite: check out the results if they are vs aren't switched to a placebo midway through. Persuasive stuff! https://t.co/qUTrF9OSpe https://t.co/RC9yO3RQKQ
Mar 2, 2023 · 2 likes · 4,287 followersView post →
SL
Srđan Lukić
@srdjl · X
U prevodu, lek semaglutid je, kao uostalom i sve drugo što je učinkovito u mršavljenju, efikasan samo dok se primenjuje, ima odličan ali vremenski i procentualno ograničen učinak i kada se ukine dolazi do rebound efekta.
Cela studija: https://t.co/BBGPDJcHXM
Feb 26, 2023 · 41 likes · 16,488 followersView post →
RH
Ryu Blockchain HODL
@ryudai94 · X
Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity
The STEP 4 Randomized Clinical Trial https://t.co/HmMYO4uq5S
@OverSaltPretzel @DrNadolsky No one real isn't recommending exercise, for anyone, it's good regardless of weight.
Semaglutide (Wegovy) works like mind blowingly well, and it's sustained. Incredible stuff and an awesome tool for folks to use. The charts are always crazy looking. https://t.co/1oHfu3mLHT https://t.co/vLhbteFESu
Dec 14, 2022 · 104 likes · 13 shares · 12,161 followersView post →
BM
Beverly G. Tchang, MD
@BevTchangMD · X
@JimJohnsonSci @CateVarney @ArianaMChao @elonmusk Not for primary prevention but there are trials looking at a related question of prevention of weight regain. Eg) https://t.co/PqQ1koKKjg
Oct 23, 2022 · 2 likes · 6,117 followersView post →
AG
Andy Grannell
@Grannell_ · X
Within the document they state long term data is not there yet so this impacts on analysis of cost effectiveness. Yet we have data that shows stopping the medication leads to regain.
https://t.co/oyh3XxJmrN
@JimJohnsonSci @StephenORahilly @DanielJDrucker There is post-treatment data from the pivotal trials of Wegovy, and a separate discontinuation arm, both of which found substantial but not complete weight regain within a few months. https://t.co/NnI2tQNbe8
@TamarHaspel This is what happened after discontinuation in STEP4, i.e., in a setting involving lifestyle intervention.
Less sharply ascending curve...
Full paper here: https://t.co/AbRJb0Vrut https://t.co/448L8sQhB2
Feb 9, 2022 · 3 likes · 38,085 followersView post →
SG
Stephan J. Guyenet
@sguyenet · X
@RomanRussy @DavidMacklinMD I think it's a fair question. I don't have granular info on this but the STEP-1 and STEP-4 semaglutide trials did report an aggregate measure of mental health and well-being, the SF-36 survey. The results favored semaglutide.
https://t.co/uA7OeBidt6
https://t.co/5q6vc0pxpH
In this RCT, weekly subcutaneous #semaglutide resulted in increased weight loss over 48 weeks vs placebo in adults with #overweight or #obesity https://t.co/tJECFXxWE8
After a 20-week run-in period with weekly semiglutide injections (mean weight loss of 10.6%), those randomized to ongoing semiglutide had sustained weight loss over the next 48 weeks (-7.9% from week 20) compared to placebo (+6.9%). @JAMA_Current https://t.co/L9oUH7dJBP
Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial https://t.co/WUBPxXlYXk
In this RCT, weekly subcutaneous subcutaneous semaglutide resulted in increased weight loss over 48 weeks vs placebo in adults with #overweight or #obesity https://t.co/Fa1e1hBIgL
Será verdad q se haya encontrado el tratamiento de la obesidad?
Effect of Weekly Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity https://t.co/QjKRs6thB8 vía @JAMA_current part of @JAMANetwork
Effect of Weekly Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity https://t.co/ssV90UKWix via @JAMA_current part of @JAMANetwork
Obesity is a risk factor for many disease states and maintaining long-term weight loss is often a challenge for many. What are your thoughts on the use of semaglutide 2.4 mg weekly? Check out the STEP 4 trial which was recently published in #JAMA.
https://t.co/0hUAn4A59e
RT @CMichaelGibson: Among overweight adults who completed a 20-week run-in period with subcutaneous #semaglutide, 2.4 mg once weekly, maint…
Mar 31, 2021 · 12 shares · 4,594 followersView post →
Y
Yeontan
@ZipBamBoomVoila · X
RT @jamecancerdoc: Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or O…
Mar 31, 2021 · 4 shares · 356 followersView post →
RM
Raj Mehta
@raj_mehta · X
RT @CMichaelGibson: Among overweight adults who completed a 20-week run-in period with subcutaneous #semaglutide, 2.4 mg once weekly, maint…
Mar 30, 2021 · 12 shares · 2,133 followersView post →
LM
Leonard Chiu, MD MS
@LeonardChiuMD · X
RT @CMichaelGibson: Among overweight adults who completed a 20-week run-in period with subcutaneous #semaglutide, 2.4 mg once weekly, maint…
Mar 30, 2021 · 12 shares · 5,749 followersView post →
DL
Dr. Oriba Dan Langoya
@DrOribaDan · X
RT @CMichaelGibson: Among overweight adults who completed a 20-week run-in period with subcutaneous #semaglutide, 2.4 mg once weekly, maint…
Mar 30, 2021 · 12 shares · 22,963 followersView post →
DG
Dr. Sue Gross
@DrSueGross · X
RT @CMichaelGibson: Among overweight adults who completed a 20-week run-in period with subcutaneous #semaglutide, 2.4 mg once weekly, maint…
Mar 30, 2021 · 12 shares · 3,030 followersView post →
Т
Татьяна
@TatiSanti10 · X
RT @CMichaelGibson: Among overweight adults who completed a 20-week run-in period with subcutaneous #semaglutide, 2.4 mg once weekly, maint…
Mar 29, 2021 · 12 shares · 1,607 followersView post →
AG
Ari Gattu
@GattuAri · X
RT @CMichaelGibson: Among overweight adults who completed a 20-week run-in period with subcutaneous #semaglutide, 2.4 mg once weekly, maint…
Mar 29, 2021 · 12 shares · 124 followersView post →
A
AngelaLoiza
@LoizaAngela · X
RT @CMichaelGibson: Among overweight adults who completed a 20-week run-in period with subcutaneous #semaglutide, 2.4 mg once weekly, maint…
Mar 29, 2021 · 12 shares · 17 followersView post →
H
hataboSAN
@hataboSAN · X
Effect of Weekly Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity https://t.co/4wp3oENRDb @JAMA_current part of @JAMANetworkより
RT @CMichaelGibson: Among overweight adults who completed a 20-week run-in period with subcutaneous #semaglutide, 2.4 mg once weekly, maint…
Mar 29, 2021 · 12 shares · 1,180 followersView post →
H施
Harold Henrison C. Chiu, MD, FPCP, FPCEDM (施君明醫師)
@88DoubleDragon · X
RT @jamecancerdoc: Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or O…
Mar 29, 2021 · 4 shares · 22,957 followersView post →
DJ
Dr. Shashank Joshi
@AskDrShashank · X
RT @CMichaelGibson: Among overweight adults who completed a 20-week run-in period with subcutaneous #semaglutide, 2.4 mg once weekly, maint…
Mar 29, 2021 · 12 shares · 32,513 followersView post →
MV
Muthu Vaduganathan
@mvaduganathan · X
RT @CMichaelGibson: Among overweight adults who completed a 20-week run-in period with subcutaneous #semaglutide, 2.4 mg once weekly, maint…
Mar 29, 2021 · 12 shares · 9,164 followersView post →
CM
C. Michael Gibson MD
@CMichaelGibson · X
Among overweight adults who completed a 20-week run-in period with subcutaneous #semaglutide, 2.4 mg once weekly, maintaining treatment with semaglutide compared with switching to placebo resulted in continued weight loss over the following 48 weeks. https://t.co/HPd3lgdQIK
Mar 29, 2021 · 27 likes · 12 shares · 432,071 followersView post →
J
JAMA
@JAMA_current · X
RT @jamecancerdoc: Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or O…
Mar 29, 2021 · 4 shares · 488,143 followersView post →
AA
andrea avila
@andrea_avilab · X
RT @EAPCPresident: Data from STEP 4 study show that 16 months of Semaglutide reduces body weight by almost 20%! It is far more effective th…
Mar 29, 2021 · 3 shares · 339 followersView post →
DS
Dr. Shatha Samargandy
@DSamargandy · X
RT @DrEenfeldt: As the recent NEJM study showed, GLP-1 once a week is a damn impressive weight-loss treatment.
But of course, if you stop…
Mar 29, 2021 · 9 shares · 4,927 followersView post →
JS
JAMA Surgery
@JAMASurgery · X
RT @jamecancerdoc: Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or O…
Mar 29, 2021 · 4 shares · 57,045 followersView post →
I
@investigando
@rocatanho · X
En adultos con sobrepeso u obesidad que completan 20 sem con semaglutide subcutáneo 2.4 mg una vez por semana, mantener el tratamiento con semaglutide resultaría en una pérdida continua de peso durante 48 sem https://t.co/X74NZgchaC a través de @JAMA_current part of @JAMANetwork
RT @EAPCPresident: Data from STEP 4 study show that 16 months of Semaglutide reduces body weight by almost 20%! It is far more effective th…
Mar 29, 2021 · 3 shares · 3,185 followersView post →
E
EAPCPresident
@EAPCPresident · X
Data from STEP 4 study show that 16 months of Semaglutide reduces body weight by almost 20%! It is far more effective than placebo treatment. Read more here: https://t.co/JKP8ZZtYuI
#EAPC_ESC
#Cardiotwitter https://t.co/ynWISIe9F3
Mar 29, 2021 · 9 likes · 3 shares · 2,516 followersView post →
PB
Public Health Bulletin
@BulletinPublic · X
Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial. https://t.co/5w7xVxFECL
En este ensayo clínico aleatorizado de adultos con sobrepeso u obesidad que completaron un período de preinclusión de 20 semanas, el mantenimiento del tratamiento con semaglutida subcutánea obtiene una pérdida de peso continua respecto del cambio a placebo
https://t.co/ih7pYPPf2C
Mar 28, 2021 · 1 share · 8,574 followersView post →
JM
Jose C Souto, MD
@jcsouto · X
RT @DrEenfeldt: As the recent NEJM study showed, GLP-1 once a week is a damn impressive weight-loss treatment.
But of course, if you stop…
Mar 27, 2021 · 9 shares · 14,595 followersView post →
JF
Jame Abraham, MD, FACP
@jamecancerdoc · X
Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial | @JAMA_current | @JAMANetworkOpen https://t.co/DqTC05Gz5Y
Mar 27, 2021 · 12 likes · 4 shares · 12,246 followersView post →
CM
Carlos Morillas
@61Morillas · X
Nuevas evidencias de la eficacia de Semaglutide 2,4 mg en estudio STEP 4. Más cerca de su aprobación para personas con obesidad @sociedadSEEN @SociedadSeedo @SVEDYN_ https://t.co/yF2WdHakMP a través de @JAMA_current part of @JAMANetwork
Mar 27, 2021 · 55 likes · 17 shares · 2,620 followersView post →
DS
Doctora.Sharly
@sharly_martinez · X
RT @DrEenfeldt: As the recent NEJM study showed, GLP-1 once a week is a damn impressive weight-loss treatment.
But of course, if you stop…
Mar 27, 2021 · 9 shares · 668 followersView post →
KP
Katherine E. Paterson
@KEPatersonRD · X
RT @AbdTahrani: STEP 4: Continuation of Semaglutide 2.4mg weekly resulted in further weight loss (WL) vs stopping treatment causing weight…
Mar 27, 2021 · 9 shares · 700 followersView post →
KB
Karlis Baltais
@karlisbaltais · X
RT @DrEenfeldt: As the recent NEJM study showed, GLP-1 once a week is a damn impressive weight-loss treatment.
But of course, if you stop…
RT @DrEenfeldt: As the recent NEJM study showed, GLP-1 once a week is a damn impressive weight-loss treatment.
But of course, if you stop…
Mar 27, 2021 · 9 shares · 158,490 followersView post →
AJ
Austin Jeans
@jeansdoc61 · X
RT @DrEenfeldt: As the recent NEJM study showed, GLP-1 once a week is a damn impressive weight-loss treatment.
But of course, if you stop…
Mar 27, 2021 · 9 shares · 964 followersView post →
K
Karageorgos
@Karageorgos15 · X
RT @DrEenfeldt: As the recent NEJM study showed, GLP-1 once a week is a damn impressive weight-loss treatment.
But of course, if you stop…
Mar 27, 2021 · 9 shares · 611 followersView post →
D
DiscoStew
@DiscoStew66 · X
RT @DrEenfeldt: As the recent NEJM study showed, GLP-1 once a week is a damn impressive weight-loss treatment.
But of course, if you stop…
Mar 27, 2021 · 9 shares · 10,798 followersView post →
DE
Dr. E
@DrEenfeldt · X
As the recent NEJM study showed, GLP-1 once a week is a damn impressive weight-loss treatment.
But of course, if you stop the drug the effect wears off and people regain weight, as shown in this new paper:
https://t.co/4xKhufnC9f https://t.co/zeCIZtVszw
Mar 27, 2021 · 29 likes · 9 shares · 62,720 followersView post →
Mar 26, 2021 · 3 likes · 1,615 followersView post →
LM
Last Week in Medicine
@lastweekinmed · X
In the STEP 4 trial of 803 overweight and obese people, those who were randomized to continue #semaglutide after 20 weeks of run-in for an additional 48 weeks had more weight loss than those who switched to placebo. #obesity @JAMANetwork #medtwitter https://t.co/meB5LyKWGx
RT @josalar13: SETP-4:with semaglutide, weight change at 68 weeks - 8% vs +7% with placebo.
@secardiologia @almucastro01
@domingomarzal @va…
Mar 26, 2021 · 3 shares · 1,005 followersView post →
JG
Jacob Gudiol
@JacobGudiol · X
Mer imponerande resultat för GLP-1 agonister när det gäller viktnedgång
Biverkningarna från den är medicinen är dock hyfsat stora men de flesta av deltagarna klarar uppenbarligen av det och väljer att fortsätta. Drygt 5% hoppade av pga biverkningar
https://t.co/THULEyEmcB https://t.co/X0RYKTryjW
Mar 26, 2021 · 12 likes · 24,402 followersView post →
SM
Sean C. Lucan, MD
@SeanLucan · X
maintaining treatment with #semaglutide compared with switching to placebo resulted in continued #weightloss.
https://t.co/zjPMLB68Pf via @JAMA_current
Great, re: subcutaneous. But what about the oral Form???
#obesity #medicine https://t.co/Dg8a6dGPdX
Mar 26, 2021 · 1 like · 1,498 followersView post →
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Susana Monereo
@SusanaMonereo · X
RT @CristobMorales: https://t.co/urzOQAgNfn Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Ad…
Mar 25, 2021 · 13 shares · 2,217 followersView post →
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the paper link
@the_paper_link · X
RT @the_paper_link: Trend new: Rubino D, ..., Step 4 Investigators (JAMA) __Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo…
RT @CristobMorales: https://t.co/urzOQAgNfn Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Ad…
Mar 24, 2021 · 13 shares · 794 followersView post →
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the paper link
@the_paper_link · X
Trend new: Rubino D, ..., Step 4 Investigators (JAMA) __Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial__
https://t.co/TVozZMVQvP
RT @DrKarlNadolsky: After completing a 20-week run-in period on semaglutide resulting over mean 10% weight loss, maintaining treatment with…
Mar 24, 2021 · 3 shares · 1,357 followersView post →
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Karl Nadolsky
@DrKarlNadolsky · X
After completing a 20-week run-in period on semaglutide resulting over mean 10% weight loss, maintaining treatment with subcutaneous semaglutide compared with switching to placebo resulted in continued weight loss.
JAMA. online March 23, 2021. doi:10.1001/jama.2021.3224 https://t.co/d8otbM5fAf
Mar 24, 2021 · 17 likes · 3 shares · 5,860 followersView post →
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SEEDO
@SociedadSeedo · X
RT @CristobMorales: https://t.co/urzOQAgNfn Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Ad…
Mar 24, 2021 · 13 shares · 10,558 followersView post →
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MANUEL PALMEZANO
@manuelpalmezano · X
RT @CristobMorales: https://t.co/urzOQAgNfn Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Ad…
Mar 24, 2021 · 13 shares · 166 followersView post →
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Juan Carlos Elizalde:.
@JuanElizalde777 · X
RT @CristobMorales: https://t.co/urzOQAgNfn Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Ad…
Mar 24, 2021 · 13 shares · 2,360 followersView post →
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Ana Sanchez Bao
@ana_sanchez_bao · X
RT @CristobMorales: https://t.co/urzOQAgNfn Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Ad…
Mar 24, 2021 · 13 shares · 1,093 followersView post →
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Cindy Manotas
@manotas_cindy · X
RT @boback: Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity:…
Mar 24, 2021 · 10 shares · 112 followersView post →
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Jennifer Clements
@jclem1027 · X
RT @boback: Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity:…
Mar 23, 2021 · 10 shares · 248 followersView post →
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Mneee3
@crafty8798 · X
RT @boback: Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity:…
Mar 23, 2021 · 10 shares · 291 followersView post →
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Leslie Vargas-Ramírez
@lilo1278 · X
RT @boback: Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity:…
Mar 23, 2021 · 10 shares · 2,448 followersView post →
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Julian mauricio Baez
@jbaez311 · X
RT @boback: Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity:…
Mar 23, 2021 · 10 shares · 28 followersView post →
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Chiayu Chen, M.D.
@ChiayuChenMD · X
RT @boback: Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity:…
Mar 23, 2021 · 10 shares · 1,105 followersView post →
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Boback Ziaeian
@boback · X
Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial @JAMA_current https://t.co/f78ymCNd0t
Mar 23, 2021 · 31 likes · 10 shares · 3,363 followersView post →
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Alejandra Fernández
@AleFer_endo · X
RT @CristobMorales: https://t.co/urzOQAgNfn Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Ad…
Mar 23, 2021 · 13 shares · 719 followersView post →
名
名前
@akkiii0830 · X
https://t.co/IutzadgzOi
Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity
The STEP 4 Randomized Clinical Trial
RT @CristobMorales: https://t.co/urzOQAgNfn Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Ad…
Mar 23, 2021 · 13 shares · 723 followersView post →
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redGDPS Diabetes
@redGDPS · X
RT @CristobMorales: https://t.co/urzOQAgNfn Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Ad…
Mar 23, 2021 · 13 shares · 15,498 followersView post →
FB
Fco Carramiñana Barrera
@fcbzafra · X
RT @CristobMorales: https://t.co/urzOQAgNfn Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Ad…
Mar 23, 2021 · 13 shares · 2,744 followersView post →
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Cristina Tejera
@cristinatejerap · X
RT @CristobMorales: https://t.co/urzOQAgNfn Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Ad…
Mar 23, 2021 · 13 shares · 11,473 followersView post →
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SGENM
@SoGENM · X
RT @CristobMorales: https://t.co/urzOQAgNfn Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Ad…
Mar 23, 2021 · 13 shares · 552 followersView post →
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Cristobal Morales
@CristobMorales · X
https://t.co/urzOQAgNfn Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity
The STEP 4 Randomized Clinical Trial @SociedadSeedo @sociedadSEEN
Mar 23, 2021 · 14 likes · 13 shares · 17,049 followersView post →
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Medicina Integrativa SABB Salud, Armonía, Bienestar y Belleza.
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JAMA. 2021;325(14): 1414-1425. doi:10.1001/jama.2021.3224 Shi Q, Wang Y, Hao Q, et al. Pharmacotherapy for adults with overweight and obesity: a systematic ...
Referencias: • STEP 4: doi:10.1001/jama.2021.3224. • SURMOUNT-4: doi:10.1001/jama.2023.24945. La investigación sobre estos medicamentos también busca ...