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The discussions highlight various aspects of amino acid metabolism, such as the importance of the urea cycle and its role in detoxification mentioned in multiple posts. Additionally, terms like 'persistent changes' and references to 'biochemical states of inflammation' illustrate a serious tone toward the implications of the research. Phrases like 'exciting achievement' convey enthusiasm, while critiques of the article's clarity suggest a nuanced engagement with both the strengths and weaknesses of the research.
Many discussions express support for the findings and methodologies presented in the article, indicating general alignment with its conclusions.
The discussions indicate a high level of curiosity, with numerous users actively engaging with and referencing specific aspects of amino acid metabolism.
While most users engage with the topic, the depth of engagement varies; some provide elaborate connections to broader metabolic processes while others express more casual interest.
There is a strong belief among participants that the publication offers significant insights that could influence future research and practical applications in the field.
BWJoneslab Moving To The University of Pittsburgh I can now officially reveal that we are moving the BWJoneslab from the University of Utah, Moran Eye Center to the University of Pittsburgh, Department of Ophthalmology, effective August 1st, 2025. bryanwjones.com/2025/06/bwjo...
title of assistant professor's talk: amino acid metabolism of effector T cells in LCMV infection title of senior full professor's talk: Why do cells eat?
Published on my birthday
Proteins of amino acid metabolism form large structures and determine diffusion in the cytoplasm! Our 7-year-long tour-de-force is now out on Bioxriv www.biorxiv.org/content/10.1... Thanks everyone involved! And especially to Jose Losa who pioneered this!
Mice lacking this amino acid lost 30% body weight www.nature.com/articles/d41... Am I missing something? Mice engineered to have a specific and severe defect in amino acid metabolism get sick and lose weight. Might the rush to find new weight loss targets be impairing our critical faculties ?
in: research I should not be reading if I actually want to sleep this 2012 (mouse) study on ACE2 receptors, intestinal inflammation, the microbiome...and amino acid metabolism Specifically, tryptophan, which is my favorite amino acid pmc.ncbi.nlm.nih.gov/articles/PMC...
This video presents free metabolism resources curated for your learning journey. Explore metabolic charts, graphics, and playlists, including insights into amino acid metabolism, which is vital for protein production…
-Olink for proteomics -UK Biobank for replication -Adjusted for BMI, eGFR, med use Tying in with other talks, some pathways identified include amino acid metabolism & endothelial dysfunction (again the hyperuricemia/ASCVD link) #GCAN2025 #ACR25
Persistent changes were seen in key metabolic hubs the urea cycle (detox in the liver), antioxidant defense, amino acid metabolism (glycine, serine, lysine), and mitochondrial energy pathways. Even recovered individuals showed a biochemical state of inflammation and low energy.
Anaplerotic and cataplerotic reactions are involved in the ultimate disposal of all metabolic intermediates. The metabolic role of anaplerosis and cataplerosis in amino acid metabolism varies with the light environment, specific organs and is dependent on the nutritional https://t.co/6zpWrtXYef
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Anaplerotic and cataplerotic reactions are involved in the ultimate disposal of all metabolic intermediates. The metabolic role of anaplerosis and cataplerosis in amino acid metabolism varies with the light environment, specific organs and is dependent on the nutritional https://t.co/x3TxEHOcu0
Anaplerotic and cataplerotic reactions are involved in the ultimate disposal of all metabolic intermediates. The metabolic role of anaplerosis and cataplerosis in amino acid metabolism varies with the light environment, specific organs and is dependent on the nutritional https://t.co/eqMT3yY7og
Anaplerotic and cataplerotic reactions are involved in the ultimate disposal of all metabolic intermediates. The metabolic role of anaplerosis and cataplerosis in amino acid metabolism varies with the light environment, specific organs and is dependent on the nutritional https://t.co/IVd6j0loV4
Anaplerotic and cataplerotic reactions are involved in the ultimate disposal of all metabolic intermediates. The metabolic role of anaplerosis and cataplerosis in amino acid metabolism varies with the light environment, specific organs and is dependent on the nutritional https://t.co/ga6WN164De
Anaplerotic and cataplerotic reactions are involved in the ultimate disposal of all metabolic intermediates. The metabolic role of anaplerosis and cataplerosis in amino acid metabolism varies with the light environment, specific organs and is dependent on the nutritional https://t.co/1pcQjeEUi1
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Single-cell RNA-seq revealed strikingly non-overlapping gene programs: HIF1A → glycolysis HIF2A → dedifferentiation, ECM remodeling, and amino acid metabolism Together, these processes provide complementary “hallmarks” that fuel oncogenesis 5/9 https://t.co/Bml7Bxh6NJ
@questmoosa Cortisol pushes amino acid metabolism toward gluconeogenesis, so the body pulls from muscle to make glucose during chronic stress. Happens even when protein intake is fine.
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@dsmchenium @thaslickpastor Biochem dzandionesa moto apa time mafinals next week ebiochem apa nhasi tatichitorova amino acid metabolism
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@sam_soete Very interesting. You could also consider the branched chain amino acid metabolism pathway which, although this article doesn't say so, is also thiamine dependent: https://t.co/yOOxtKT8jc
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RT @MetabolitesMDPI:
RT @MetabolitesMDPI:
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@shibumppo @jakeshieldsajj @elonmusk @RobertKennedyJr @KramerNation Thanks for the link! This Khan Academy overview on amino acid metabolism is spot-on for our chat—love how it breaks down transamination and the urea cycle for nitrogen detox. Relates directly to glycine mimics like glyphosate potentially disrupting those carbon backbones in
@shibumppo @jakeshieldsajj @elonmusk @RobertKennedyJr @KramerNation You're right—there's often a gap in integrating protein synthesis with metabolic outcomes. Studies (e.g., 2025 Frontiers in Endocrinology) link disruptions in amino acid metabolism and transporters like SLC7 to insulin resistance and obesity, via impaired protein folding and ER
Results Childhood trauma was associated in a dose-response manner with 18 metabolites. Upregulated metabolites were nominally enriched with compounds involved in fatty acid and branched-chain amino acid metabolism (p = 3.91 × 10−2, false discovery rate–corrected q [qFDR] > .05)
RT @FrontMicrobiol: New Research: Cellular respiration and amino acid metabolism is altered by dietary oligosaccharides in Salmonella with…
5) Vitamin B6 (Pyridoxine) - What it does: Involved in amino acid metabolism, neurotransmitter synthesis, and hemoglobin production. - Sources: Poultry, fish, bananas, potatoes, beef liver. - Deficiency: Depression, confusion, irritability, and anemia. https://t.co/iHThL1QC8L
New Research: Cellular respiration and amino acid metabolism is altered by dietary oligosaccharides in Salmonella with epithelial cell association https://t.co/y10VegomR4 #FrontiersIn #Microbiology
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Astragaloside Ⅳ improves neuroinflammation in Parkinson's disease by regulating amino acid metabolism and the PI3K-AKT signaling pathway Shanxi University of Chinese Medicine Neuropharmacology. 2025 Aug 28;280:110661.
@alexandrer81988 @HollyMars2 Four types of neuro damage listed above don't even include potential changes to amino acid metabolism that pw LC ME deal with impacting the availability of neurotransmitters necessary for proper brain function. Nor how a damaged brain can lose control of inflammation/autonomic .
Incidence of phenylketonuria and other inborn errors of the amino acid metabolism in the normal and mentally retarded population https://t.co/AG59GlARLy
#FruitRes Unlocking kiwifruit flavor secrets!
#FruitRes Unlocking kiwifruit flavor secrets!
Aqueous extract of Acer truncatum leaves retards Drosophila melanogaster senescence by regulating amino acid metabolism and gut microbiota #Drosophila
Aqueous extract of Acer truncatum leaves retards Drosophila melanogaster senescence by regulating amino acid metabolism and gut microbiota #Drosophila
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Use of a glucagon receptor antagonist after total pancreatectomy did not reveal a physiological role of extrapancreatic glucagon in glucose, lipid &amino acid metabolism during OGTT. link.springer.com/article/10.1...
RT @biorxiv_micrbio: Contrasting effects of glutamate and branched-chain amino acid metabolism on acid tolerance in a Castellaniella isolat…
RT @DiabetologiaJnl: Use of a glucagon receptor antagonist after total pancreatectomy did not reveal a physiological role of extrapancreati…
RT @DiabetologiaJnl: Use of a glucagon receptor antagonist after total pancreatectomy did not reveal a physiological role of extrapancreati…
Use of a glucagon receptor antagonist after total pancreatectomy did not reveal a physiological role of extrapancreatic glucagon in glucose, lipid &amino acid metabolism during OGTT. @HerlevGentofte @UCPH_health @UCPH_Research @AsgerBachLund @Filip_Knop https://t.co/CgN1VR8GGV
Contrasting effects of glutamate and branched-chain amino acid metabolism on acid tolerance in a Castellaniella isolate from acidic groundwater https://www.biorxiv.org/content/10.1101/2025.09.26.678905v1
Contrasting effects of glutamate and branched-chain amino acid metabolism on acid tolerance in a Castellaniella isolate from acidic groundwater https://www.biorxiv.org/content/10.1101/2025.09.26.678905v1
Contrasting effects of glutamate and branched-chain amino acid metabolism on acid tolerance in a Castellaniella isolate from acidic ... https://t.co/ktwrwc9nJA #biorxiv_micrbio
@NancyLaporte3 @gracels @NatashaCL7 Vitamin B6 (pyridoxine) plays key roles in amino acid metabolism, neurotransmitter synthesis (e.g., serotonin, GABA), hemoglobin production, and immune function, per NIH and Mayo Clinic. In glutathione context, it's involved in pathways supporting GSH synthesis and antioxidant
@Tonmapu @BioProtocol @Aubrai_ Interesting insights on a-KG extending lifespan by inhibiting ATP synthase and TOR, linking amino acid metabolism with anti-aging effects.
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@ClideDave There's only so much amino acid metabolism I can take
Use of skeletal muscle fiber composition to assess relationship between amino acid metabolism and insulin sensitivity https://t.co/Qf3xNVDDI0
- This study used skeletal muscle fiber composition to investigate whether defects in amino acid metabolism are involved in the early development of insulin resistance in healthy young individuals before onset of clinical manifestations.
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Functional and metabolomic analyses of brown adipose tissue during cold-deacclimation reveal rapid adaptations in N-acetylated amino acid metabolism https://t.co/zsMPJoZZot
Functional and metabolomic analyses of brown adipose tissue during cold-deacclimation reveal rapid adaptations in N-acetylated amino acid metabolism https://www.biorxiv.org/content/10.1101/2025.09.23.678072v1
Functional and metabolomic analyses of brown adipose tissue during cold-deacclimation reveal rapid adaptations in N-acetylated amino acid metabolism https://www.biorxiv.org/content/10.1101/2025.09.23.678072v1
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But only academics. Bankers and Jimmy Johns managers and grocery store employees don't have to. Again, wtf would a biologist need to study edgelords? And wtf is meatspace? You all live in a bubble. Do you know anything about amino acid metabolism? If not, shame on you. It affects you daily.
Serum Metabolomics Reveal Disrupted Amino Acids in Parkinson’s In a groundbreaking study published recently, researchers have uncovered critical disruptions in amino acid metabolism linked to Parkinson’s disease, shedding new light on the complex biochemical underpinnings of this neurodegenerative…
RT @FrontMicrobiol: New Research: Exploring the antibacterial potential of arthrocolins against extensively drug-resistant Pseudomonas aeru…
RT @MetabolitesMDPI:
RT @MetabolitesMDPI:
RT @FrontMicrobiol: New Research: Exploring the antibacterial potential of arthrocolins against extensively drug-resistant Pseudomonas aeru…
New Research: Exploring the antibacterial potential of arthrocolins against extensively drug-resistant Pseudomonas aeruginosa: mechanistic insights into amino acid metabolism disruption https://t.co/FEvPlW1r7p #FrontiersIn #Microbiology
#UCP2 regulates branched-chain amino acid metabolism by modulating the PI3K/AKT/mTOR signaling axis, providing new insights into the mechanisms of #Leukemogenesis. @shanghai-jiao-tong-university-school-of-medicine #medsky #OpenAccess: www.sciencedirect.com/science/arti...
@jules_1094 @degengod_sol @AutismCapital Folate, or vitamin B9, is essential for DNA synthesis and repair, red blood cell formation (preventing anemia), cell growth, and amino acid metabolism. It's crucial during pregnancy for fetal neural tube development. Sources: Mayo Clinic, NIH, MedlinePlus.
Trend new: Ran B, ..., Wu J (J Adv Res) __Dynamic remodeling of amino acid metabolism in tumor-associated macrophages: Fueling immunosuppression, reshaping tumor niches, and unlocking metabolic checkpoints__ https://t.co/ldImmSfTLU
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RT @CraigAGoodman1: Use of skeletal muscle fiber composition to assess relationship between amino acid metabolism and insulin sensitivity h…
RT @CraigAGoodman1: Use of skeletal muscle fiber composition to assess relationship between amino acid metabolism and insulin sensitivity h…
Use of skeletal muscle fiber composition to assess relationship between amino acid metabolism and insulin sensitivity academic.oup.com/ejendo/advan...
Use of skeletal muscle fiber composition to assess relationship between amino acid metabolism and insulin sensitivity https://t.co/8hwQRuh5Bn
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Inhibition of the glucagon receptor using LY2409021 during OGTT in totally pancreatectomised individuals does not produce detectable effects on glucose, lipid or amino acid metabolism @diabetologiajnl.bsky.social link.springer.com/article/10.1...
Inhibition of the glucagon receptor using LY2409021 during OGTT in totally pancreatectomised individuals does not produce detectable effects on glucose, lipid or amino acid metabolism @DiabetologiaJnl https://t.co/qRNNMV0HQu
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DL-Alanine can serve as a raw material for producing antibiotics, heparin, and other medicines. It plays a vital role in amino acid metabolism in medical microbiology and biochemistry.
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REPLAY: Fine Tuning Mitochondrial Function Part 4 https://t.co/InNsJ6AIUI Last week, Dr. Watts continued the mitochondria conversation. In earlier episodes, he covered fatty acids and carbohydrates, and last week he tackled amino acid metabolism cascades. Watch it now! https://t.co/pNh1sPgVn6
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Many focus on GLP-1s for glucose and weight, but their influence extends to amino acid metabolism. Specifically, they can help normalize levels of branched-chain amino acids (BCAAs). #GLP1Insights #MetabolicHealth
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@hjggjyygyg @BioProtocol @microbiomedao
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#PubSaludMurcia Alterations in hepatic amino acid metabolism related to MASLD in individuals with obesity @AreaUnoArrixaca
The findings reveal that indoxacarb disrupts the insect's purine and amino acid metabolism, leading to mitochondrial damage and impaired growth, movement, and feeding.
This study investigates the role of the ACSS2-PPARD-BCAT1 axis in regulating branched-chain amino acid metabolism and pancreatic cancer progression.
Discover how a metabolic enzyme, ACSS2, synchronizes branched-chain amino acid metabolism and cancer development in pancreatic tumors, offering a promising new therapeutic target.
We're hiring! We're recruiting a post-doc to join my lab at Barts Cancer Institute in London investigating amino acid metabolism in lymphoma biology. Apply here: qmul-jobs.tal.net/vx/mobile-0/...
These findings reveal a mechanistic link between oncogene fluctuation, amino acid metabolism, and immune evasion, positioning AHR as a central mediator of EwS progression and a tractable therapeutic vulnerability. 7/n
boulardii undergoes morphological changes, increases antioxidant enzyme activity, and significantly alters gene expression - particularly in pathways related to carbohydrate transport, amino acid metabolism, and ribosome biogenesis.
#PubSaludMurcia Alterations in hepatic amino acid metabolism related to MASLD in individuals with obesity @AreaUnoArrixaca
This sounds like an exciting achievement! The role of amino acid metabolism in forming protein structures and diffusion is fascinating. Congratulations on the release! Can you share a bit more about the key findings or impacts of your research?
A. baumannii’s nutrient tug-of-war A. Wolf highlights recent @laurenpalmer.bsky.social paper establishing a murine model to define how amino acid metabolism shapes long-term A. baumannii colonization www.cell.com/cell-host-mi...
-Severe COVID : Elevated blood glucose and mannose levels, changes in amino acid metabolism, reliance on glycolysis & glutaminolysis for viral replication are noted. - MIS-C: Studies point to alterations in lipid classes and elevated inflammatory markers. pubs.acs.org/doi/10.1021/...
Amino acid metabolism shapes the tumor immune microenvironment and therapy response ->News-Medical | More info from EcoSearch
In a new review published in Cancer Biology & Medicine, scientists from Tongji University Cancer Center explored how amino acid metabolism governs the intricate dialogue between cancer cells and immune defenses. #TME #aminoacid Details: doi.org/10.20892/j.issn.2095-3941.2025.0115
In the coral host, we observed dawn as a molecular surge in RNA metabolism
#pwME BCCA or CoQ10 (or acetyl-L-Carnitine, B2 etc) for the disrupted bile acid, lipid & amino acid metabolism piece in Myalgic Encephalomyelitis/CFS? 2/3
The researchers found that CCH led to disruptions in amino acid metabolism and synaptic function, which were reversed by BCAA supplementation.
Rewiring amino acid metabolism to boost nonnatural polyketide production in Yarrowia lipolytica https://www.biorxiv.org/content/10.1101/2025.08.03.668335v1
Rewiring amino acid metabolism to boost nonnatural polyketide production in Yarrowia lipolytica https://www.biorxiv.org/content/10.1101/2025.08.03.668335v1
Ophthopedia Update: Amino Acid Metabolism and Photoreceptor Degenerative Diseases: Mechanisms, Early Diagnosis, and Therapeutic Prospects: Publication date: Available online 29 July 2025 Source: Experimental Eye Research Author(s): Qin Zhang, Bintao Xie, Liujun Ding, Lue Xiang, Jing Wang, Jineng…
4) The authors speak of "a fundamental disruption in amino acid metabolism," but it's still unclear what this means, and this was an exploratory study that needs to be confirmed first by other studies. Link to the study: www.mdpi.com/1422-00...
Gut microbial bile and amino acid metabolism associate with peanut oral immunotherapy failure @natcomms.nature.com www.nature.com/articles/s41...
Dose-Dependent Effects of Butachlor Accumulation and Degradation on Amino Acid Metabolism and Lignin Biosynthesis in Rice #EnvironPollut #MassSpec www.sciencedirect.com/science/arti...
Targeting the amino acid metabolism in Lung Sarcopenia: A Systems Engineering Approach https://www.biorxiv.org/content/10.1101/2025.06.30.662260v1
Targeting the amino acid metabolism in Lung Sarcopenia: A Systems Engineering Approach https://www.biorxiv.org/content/10.1101/2025.06.30.662260v1
Ulk1(S555) inhibition alters nutrient stress response by prioritizing amino acid metabolism https://www.biorxiv.org/content/10.1101/2025.06.30.662412v1
Ulk1(S555) inhibition alters nutrient stress response by prioritizing amino acid metabolism https://www.biorxiv.org/content/10.1101/2025.06.30.662412v1
Proteins of amino acid metabolism form large structures and determine diffusion in the cytoplasm! Our 7-year-long tour-de-force is now out on Bioxriv www.biorxiv.org/content/10.1... Thanks everyone involved! And especially to Jose Losa who pioneered this!
Citrocin, an antimicrobial peptide widely used in animal feed, has strong anti-biofilm effects against the foodborne pathogen L. monocytogenes; the compound limits bacterial motility & suppresses biofilm-related amino acid metabolism. #JournalSpectrum: asm.social/2ty
Fantastic work by the Dixit lab at Yale sheds light on how amino acid metabolism directly influences adipose tissue function and browning @natrevendo.nature.com #metabolism #obesityresearch rdcu.be/etksL
Shengjie Zhang et al. from Shanghai Jiao Tong University School of Medicine show that BCAT1 activation reprograms branched-chain amino acid metabolism and epigenetically promotes inflammation in diabetic retinopathy. doi.org/10.1167/iovs.66.6.59
Very cool! Interesting that glucose and amino acid metabolism are required
Besides MEN1, other rare hereditary syndromes can cause pancreas NET. See our recent publication on the first family with Mahvash disease due to glucagon receptor mutations. Interesting how glucagon signaling knockout affects amino acid metabolism, not glucose. erc.bioscientifica.com/doi/10.1530/...
(Biomed Chrom) Metabolomics Analysis Reveals That Anoectochilus roxburghii Extract Enhances Immunity in Immunosuppressed Rats by Modulating Lipid Metabolism and Amino Acid Metabolism: ABSTRACT Anoectochilus roxburghii (AR) has been reported to exhibit immunomodulatory… #massSpecRSS #biomedchrom
Pcbp1 orchestrates amino acid metabolism burst during the naive-to-primed pluripotency transition https://www.biorxiv.org/content/10.1101/2025.06.07.658314v1
Pcbp1 orchestrates amino acid metabolism burst during the naive-to-primed pluripotency transition https://www.biorxiv.org/content/10.1101/2025.06.07.658314v1
HDAC7 promotes renal cancer progression by reprogramming branched-chain amino acid metabolism Science Advances www.science.org/doi/10.1126/...
BWJoneslab Moving To The University of Pittsburgh I can now officially reveal that we are moving the BWJoneslab from the University of Utah, Moran Eye Center to the University of Pittsburgh, Department of Ophthalmology, effective August 1st, 2025. bryanwjones.com/2025/06/bwjo...
Exciting new work by @yasesancak.bsky.social in Science Advancase showing how mitochondrial Ca2 fluxes control branched chain amino acid metabolism. Mitochondrial Ca2 is not just about the TCA cycle!
Microbial synthesis of branched-chain β,γ-diols from amino acid metabolism www.nature.com/articles/s41...
Mice lacking this amino acid lost 30% body weight www.nature.com/articles/d41... Am I missing something? Mice engineered to have a specific and severe defect in amino acid metabolism get sick and lose weight. Might the rush to find new weight loss targets be impairing our critical faculties ?
title of assistant professor's talk: amino acid metabolism of effector T cells in LCMV infection title of senior full professor's talk: Why do cells eat?
Thiamin (vitamin B1) serves as a cofactor for a variety of enzymes involved in carbohydrate and amino acid metabolism, RNA and DNA production, and generating energy for the Krebs cycle. Good sources include organ meats, pork, squash, seeds, fish, yeast, legumes, and whole grains.
#PubSaludMurcia Alterations in hepatic amino acid metabolism related to MASLD in individuals with obesity @AreaUnoArrixaca
Metabolomic analysis reveals key changes in amino acid metabolism in colorectal cancer patients #AminoAcids #MassSpec link.springer.com/article/10.1...
Amino Acid Metabolism and Transporters in Plant−Pathogen Interactions: Mechanisms and Implications onlinelibrary.wiley.com/doi/10.1111/...
Effects of risperidone on amino acid metabolism, glucose, and kidney function in healthy adults: A pilot randomized controlled trial https://www.medrxiv.org/content/10.1101/2025.04.24.25326340v1
This Review from Phillip J. White, Nicolai J. Wewer Albrechtsen & Jonathan E. Campbell explores islet hormones at the intersection of glucose and amino acid metabolism (£) go.nature.com/3S26jDE #EndoSky #WorldHormoneDay #BecauseHormonesMatter
The Diabetes Gene Tcf7l2 Organizes Gene Expression in the Liver and Regulates Amino Acid Metabolism https://www.biorxiv.org/content/10.1101/2025.04.03.647067v1
The Diabetes Gene Tcf7l2 Organizes Gene Expression in the Liver and Regulates Amino Acid Metabolism https://www.biorxiv.org/content/10.1101/2025.04.03.647067v1
Pimento cheese sammiches (with plenty of dill); macaroni salad; avalanche bark. Not pictured: mug of coffee. Citric acid helps reduce the impact of sulfur-based amino acid metabolism by buffering against acidosis, assuming the kidney works a bit. Instead of plain water, add splash of lemon juice.
in: research I should not be reading if I actually want to sleep this 2012 (mouse) study on ACE2 receptors, intestinal inflammation, the microbiome...and amino acid metabolism Specifically, tryptophan, which is my favorite amino acid pmc.ncbi.nlm.nih.gov/articles/PMC...
Interesting articles about the Metabolomic changes in children with autism. "Serotonin is crucial in social interaction and emotional regulation. Therefore, the reduction of serotonin could potentially influence mood, social interactions, and other behaviors associated with ASD."
Happy to see our collaborative paper "Metatranscriptomic analysis reveals gut microbiome bacterial genes in pyruvate and amino acid metabolism associated with hyperuricemia and gout in humans" already published www.nature.com/articles/s41...
From Sweden: Systemic Multi-Omics Analysis Reveals Interferon Response Heterogeneity and Links Lipid Metabolism to Immune Alterations in Severe COVID-19 www.biorxiv.org/content/10.1... From the latest Science for ME weekly update #LongCovid #PASC
3rd year student Maggie Cassidy (@margaretmcass) in the @AhrensNicklas and @AnaGCristancho labs with a new review article - Branched Chain Amino Acid Metabolism in Developmental Brain Injury: Putative Mechanisms and Therapeutic Potential
"reveal a stochastic relationship between [Interferon Stimulated Genes] expression and immune cell activation, along with significant perturbations in lipid and amino acid metabolism." "evidence suggests that dysregulated ISG expression may contribute to post-viral syndromes such as #LongCOVID"
Delineation of signaling components downstream of the GCGR highlights a critical role for hepatic PKA , but not EPAC2 to control amino acid metabolism, and the liver-alpha cell axis #islets diabetesjournals.org/diabetes/art...
Cellular Respiration and Amino Acid Metabolism Is Altered by Dietary Oligosaccharides in Salmonella www.biorxiv.org/content/bior...
Cellular Respiration and Amino Acid Metabolism Is Altered by Dietary Oligosaccharides in Salmonella During Epithelial Association https://www.biorxiv.org/content/10.1101/2025.03.09.642302v1
Cellular Respiration and Amino Acid Metabolism Is Altered by Dietary Oligosaccharides in Salmonella During Epithelial Association https://www.biorxiv.org/content/10.1101/2025.03.09.642302v1
White et al. discussed the actions of each islet hormone alone and in combination with the others in regulating glucose and amino acid metabolism and explored how these signalling networks are closely linked and strongly influence one another.
ICYMI: New content online: Islet hormones at the intersection of glucose and amino acid metabolism
New content online: Islet hormones at the intersection of glucose and amino acid metabolism
Delighted to see our review: "Islet hormones at the intersection of glucose and amino acid metabolism" online today @naturerevendo.bsky.social was an absolute pleasure to write this with Jon and Nicolai You can bypass the paywall here: rdcu.be/ecAhm
Phage reprogramming of Pseudomonas aeruginosa amino acid metabolism drives efficient phage replication. DOI: 10.1128/mbio.02466-24 https://pubmed.ncbi.nlm.nih.gov/39918338/
Next, Kshitija Rahate on Candida. Coculturing of fungal and human cells coupled with multiomics highlights metabolic pathways involved, including amino acid metabolism #ecfg17
9/n “protected proteins” (autophagy targets) include cytolytic effectors; amino acid, glucose and lactate transporters; as well as proteins involved in metabolism (FAO, amino acid metabolism, and glycolysis)
Yes I did! Great animations! A lot of my research deals with the loss of carbon and nitrogen during amino acid metabolism. The Krebs cycle visualization is amazing to get people to follow the loss of C in particular! I’m going to have it in my PhD defense talk in a couple months!
(J Chrom B) Integration of UHPLC-MS and mass spectrometry imaging techniques revealed the protective mechanism of Gushudan in postmenopausal osteoporosis rats via branched-chain amino acid metabolism based on the ‘kidney-bone’ axis: Publication date:… http://dlvr.it/TJCfT3 #JChrom #MassSpecRSS
Integration of UHPLC-MS and mass spectrometry imaging techniques revealed the protective mechanism of Gushudan in postmenopausal osteoporosis rats via branched-chain amino acid metabolism based on the ‘kidney-bone’ axis #JChromB www.sciencedirect.com/science/arti...
Our latest new study shows that stimulant & non-stimulant #ADHD meds affect lipid & amino acid metabolism in similar ways—challenging the idea that they work differently! Even amlodipine mimics their effects, further supporting it's potential
Cell & C. elegans models for understanding amino acid metabolism. Leucine deprivation has roles in lysosome biogenesis (storage v/s degradative compartments). Urmi Bandyopadhyay MIRM-MAHE #M2T22025 IIT-Jodhpur
Join us and FRIDAY FEB 21 at NOON CST for Robin daSilva to hear about "Amino Acid #metabolism and #immune signaling in #liver disease" in person at A207 Chown @um-radyfhs.bsky.social or via ZOOM 681 3842 0399 PW: 808380
Phage reprogramming of Pseudomonas aeruginosa amino acid metabolism drives efficient phage replication | mBio https://journals.asm.org/doi/full/10.1128/mbio.02466-24
Branched-chain amino acid metabolism supports Roseobacteraceae positive interactions in marine biofilms journals.asm.org/doi/full/10.... #jcampubs
Phage reprogramming of Pseudomonas aeruginosa amino acid metabolism drives efficient phage replication #mBio from @themaxwelllab.bsky.social journals.asm.org/doi/10.1128/...
Alzheimer disease, Multiple Myloma, Amino Acid Metabolism Disorder - those are the diseases that have taken from me. What has taken form you? wapo.st/3Q9DrIH
Published on my birthday
New in the main journal: Contribution of Brain Intrinsic Branched-Chain Amino Acid Metabolism in a Novel Mouse Model of Maple Syrup Urine Disease Amanda Kuhs, et al @AhrensNicklas doi.org/10.1002/jimd...
Branched chain amino acid metabolism and microbiome in adolescents with obesity during weight loss therapy. https://www.medrxiv.org/content/10.1101/2025.02.03.25321363v1
Unraveled cancer cell survival-associated amino acid metabolism of HepG2 cells altered by Thai rat-tailed radish microgreen extract examined by untargeted LC-MS/MS analysis #FoodChem www.sciencedirect.com/science/arti...
My drawing of the glucose-alanine cycle, a part of amino acid metabolism. I made this diagram with Affinity Designer. #biochemistry #metabolism
Plasma metabolome reveals altered oxidative stress, inflammation, and amino acid metabolism in dogs with idiopathic epilepsy #Epilepsia #MassSpec onlinelibrary.wiley.com/doi/10.1111/...
SlTOR regulates cold tolerance via amino acid metabolism in tomato. #TORMechanism @OxfordJournals Details: doi.org/10.1093/hr/u...
"Altogether, the six compounds caused changes in biological pathways involved in hypoxia signaling, oxidative stress, protein synthesis and amino acid metabolism, all of which are crucial for neuronal function and development."
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