The group’s conversations reveal skepticism and disappointment, exemplified by phrases like 'null results' and 'no effect,' as well as dismissals of the supplement's efficacy. Words like 'meh' and 'disappointing' highlight a tone of skepticism and low enthusiasm, showing that the study's findings are seen as undermining previous positive beliefs about nattokinase’s benefits.
AgreementStrong disagreement
The majority of discussions express disappointment or skepticism about the study's findings, indicating strong disagreement with the idea that nattokinase is effective for heart health.
InterestNeutral interest
Posts show moderate interest, mainly reacting to the study's results without deeper exploration or curiosity, often dismissing or criticizing the findings.
EngagementLow engagement
Many comments reflect superficial reactions or dismissive attitudes, with few engaging in detailed analysis of the methodology or implications.
ImpactLow impact
Overall, the social discussions suggest minimal impact on beliefs or practices, as the consensus appears to be that the research challenges prior claims and leaves little room for influence.
Abstract in brief
The study tested whether nattokinase, a supplement thought to benefit heart health, actually slows down the development of early atherosclerosis and improves related blood markers.
Over about 3 years, participants taking nattokinase showed no significant difference in the progression of artery wall thickness or stiffness compared to those taking a placebo.
The results suggest that nattokinase does not have a meaningful effect on preventing or reducing early signs of heart disease in healthy people at low risk.]
1. Lower Doses Ineffective for Atherosclerosis
A study found that lower doses of nattokinase (2,000 FU) did not significantly impact the progression of subclinical atherosclerosis (https://t.co/QnRPr0nolE.)
Jan 2, 2025 · 92 likes · 7 shares · 74,668 followersView post →
L
LongCovidPharmD
@organichemusic · X
However, this larger RCT from 2021 concluded that after a median 3 yrs, daily 2000 FU NK showed no significant effect on blood coagulation and fibrinolysis factors, blood pressure or any other tested labs, & didn't decrease https://t.co/mmDq0h4l58 https://t.co/nPNzB6Clpn
Jun 10, 2022 · 82 likes · 12 shares · 35,447 followersView post →
MP
Mike Lustgarten, PhD
@mike_lustgarten · X
Nattokinase atherothrombotic prevention study: A randomized controlled trial https://t.co/onigGsKWAW
Feb 14, 2025 · 15 likes · 1 share · 9,745 followersView post →
MB
Matt Brignall
@drbrignall · X
Because a prominent anti-vaxxer is now hawking nattokinase to something something vaccine blood etc, now is a good time to share the first clinical trial on this supplement. Spoiler: no effect.
https://t.co/WdLmyy56Vv
Feb 21, 2023 · 10 likes · 3 shares · 2,027 followersView post →
KP
Karoyan Philippe
@KaroyanPhilippe · X
@barriere_dr Je ne comprends pas comment on peut croire qu’un enzyme, qui est une proteine, puisse sans dégradation, passer la barrière du tube digestif (estomac, intestin, foie) pour ensuite aller dégrader une autre protéine (spike) dans le sang. Pour les sceptiques:https://t.co/VVtU8dSgsN
@wideawake_media Hodis2021:
at no time point, incl. early time points of 1 wk+1,3&6m post-randomization, did nattokinase suppl. have a detectable treatment effect on any coagulation factor, fibrinolytic factor or platelet aggregation rel. to placebo
https://t.co/7wz5kH3Avl
https://t.co/hIgVz4oBC0
Nov 14, 2023 · 6 likes · 3 shares · 2,395 followersView post →
The study found that consuming nattokinase, a fermented soy extract, can reduce blood pressure in hypertensive individuals, especially in males, and decrease cardiovascular risk markers like von Willebrand factor…
This study tested whether nattokinase, a supplement thought to benefit heart health, actually slows down the development of early atherosclerosis and improves related blood markers. Over about 3 years, participants…
1. Lower Doses Ineffective for Atherosclerosis
A study found that lower doses of nattokinase (2,000 FU) did not significantly impact the progression of subclinical atherosclerosis (https://t.co/QnRPr0nolE.)
Jan 2, 2025 · 92 likes · 7 shares · 74,668 followersView post →
JB
Joe Blow
@josephblosef · X
@EchoplexSE @Cernovich https://t.co/rBZWNJStSb lol “some studies” means studies by the people who sell it. Real studies say it’s meh
Dec 14, 2024 · 1 like · 8,817 followersView post →
WL
William Lagakos
@caloriesproper2 · X
Mixed evidence of Nattokinase on blood pressure.
Positive (8-week study): https://t.co/g95QEBKe00
Neutral (3 years): https://t.co/uYyxprGDH7
Both used the same dose: 2000 fibrinolytic units/d
Dec 14, 2024 · 2 likes · 3,244 followersView post →
A 2017 clinical trial in China found that a dose of 6,000 FU/day was effective https://t.co/znqxFpIoPs
But a 2021 clinical trial found that a dose of 2,000 FU/day wasn't effective https://t.co/6ZsFAnZx4X
RT @sandoly: @wideawake_media Hodis2021:
at no time point, incl. early time points of 1 wk+1,3&6m post-randomization, did nattokinase suppl…
Nov 20, 2023 · 3 shares · 180 followersView post →
WA
Water From Air
@MoistureVapor8r · X
RT @sandoly: @wideawake_media Hodis2021:
at no time point, incl. early time points of 1 wk+1,3&6m post-randomization, did nattokinase suppl…
Nov 19, 2023 · 3 shares · 4,475 followersView post →
SS
Szabolcs Sandoly
@sandoly · X
@wideawake_media Hodis2021:
at no time point, incl. early time points of 1 wk+1,3&6m post-randomization, did nattokinase suppl. have a detectable treatment effect on any coagulation factor, fibrinolytic factor or platelet aggregation rel. to placebo
https://t.co/7wz5kH3Avl
https://t.co/hIgVz4oBC0
Nov 14, 2023 · 6 likes · 3 shares · 2,395 followersView post →
VV
Volkhart Vester
@VesterVolkhart · X
@Sabsi0431 @DrSynthetiks @reitschuster 2000IU haben keinen Effekt auf Arteriosklerose
https://t.co/oLVvyG3xoR
@barriere_dr Je ne comprends pas comment on peut croire qu’un enzyme, qui est une proteine, puisse sans dégradation, passer la barrière du tube digestif (estomac, intestin, foie) pour ensuite aller dégrader une autre protéine (spike) dans le sang. Pour les sceptiques:https://t.co/VVtU8dSgsN
Well .. darn .. they RCT’d my latest N=1 (nattokinase) and found no benefit. But, only used 2000FU. Most papers seem to indicate 10000FU.
https://t.co/oTr0LTfVwI
Nattokinase RCT- 3 yrs of treatment: “Results of this trial show that nattokinase supplementation has a null effect on subclinical atherosclerosis progression in healthy individuals at low risk for CVD” https://t.co/7qvADqUvoG
Mar 9, 2023 · 3 likes · 5,425 followersView post →
T
Tj
@cali_tami · X
RT @drbrignall: Because a prominent anti-vaxxer is now hawking nattokinase to something something vaccine blood etc, now is a good time to…
Feb 23, 2023 · 3 shares · 2,547 followersView post →
LR
(((Liz Ditz))). Mask up, y'all. Viruses are real.
@lizditz · X
RT @drbrignall: Because a prominent anti-vaxxer is now hawking nattokinase to something something vaccine blood etc, now is a good time to…
Feb 21, 2023 · 3 shares · 10,456 followersView post →
MB
Matt Brignall
@drbrignall · X
Because a prominent anti-vaxxer is now hawking nattokinase to something something vaccine blood etc, now is a good time to share the first clinical trial on this supplement. Spoiler: no effect.
https://t.co/WdLmyy56Vv
Feb 21, 2023 · 10 likes · 3 shares · 2,027 followersView post →
AA
Anomic Aphasia
@AphasiaAnomic · X
@florpodesta5 @useless_priest Large, randomized, controlled clinical trial, no effect for nattokinase. https://t.co/f1YpZyJrRj Proteins are simply not effectively delivered across the gut barrier in healthy persons. If your blood was ‘gellish’ before, see a doctor. But enjoy your placebo effect.
RT @organichemusic: However, this larger RCT from 2021 concluded that after a median 3 yrs, daily 2000 FU NK showed no significant effect o…
Jun 20, 2022 · 12 shares · 11,325 followersView post →
HP
Howard Phillips
@SirDagon · X
RT @organichemusic: However, this larger RCT from 2021 concluded that after a median 3 yrs, daily 2000 FU NK showed no significant effect o…
Jun 11, 2022 · 12 shares · 1,093 followersView post →
TI
The Left Independent ✊
@Left_Indy · X
RT @organichemusic: However, this larger RCT from 2021 concluded that after a median 3 yrs, daily 2000 FU NK showed no significant effect o…
Jun 10, 2022 · 12 shares · 2,917 followersView post →
AK
AMARESH KUMAR
@amareshskumar · X
RT @organichemusic: However, this larger RCT from 2021 concluded that after a median 3 yrs, daily 2000 FU NK showed no significant effect o…
Jun 10, 2022 · 12 shares · 1,277 followersView post →
C
Constellation
@Clear_Purpose · X
RT @organichemusic: However, this larger RCT from 2021 concluded that after a median 3 yrs, daily 2000 FU NK showed no significant effect o…
Jun 10, 2022 · 12 shares · 233 followersView post →
SJ
Sue Jackson
@SueJack41372586 · X
RT @organichemusic: However, this larger RCT from 2021 concluded that after a median 3 yrs, daily 2000 FU NK showed no significant effect o…
Jun 10, 2022 · 12 shares · 239 followersView post →
CE
CM they/them ASD EDS MDD OA etc
@CM_7505 · X
RT @organichemusic: However, this larger RCT from 2021 concluded that after a median 3 yrs, daily 2000 FU NK showed no significant effect o…
Jun 10, 2022 · 12 shares · 1,686 followersView post →
PB
Paul B |
@Paul_Briley · X
RT @organichemusic: However, this larger RCT from 2021 concluded that after a median 3 yrs, daily 2000 FU NK showed no significant effect o…
Jun 10, 2022 · 12 shares · 6,212 followersView post →
C
Cissi
@_Cissi__ · X
RT @organichemusic: However, this larger RCT from 2021 concluded that after a median 3 yrs, daily 2000 FU NK showed no significant effect o…
Jun 10, 2022 · 12 shares · 203 followersView post →
AH
Angela Howard
@AngelaH40381359 · X
RT @organichemusic: However, this larger RCT from 2021 concluded that after a median 3 yrs, daily 2000 FU NK showed no significant effect o…
Jun 10, 2022 · 12 shares · 16 followersView post →
L
LongCovidPharmD
@organichemusic · X
However, this larger RCT from 2021 concluded that after a median 3 yrs, daily 2000 FU NK showed no significant effect on blood coagulation and fibrinolysis factors, blood pressure or any other tested labs, & didn't decrease https://t.co/mmDq0h4l58 https://t.co/nPNzB6Clpn
Jun 10, 2022 · 82 likes · 12 shares · 35,447 followersView post →
Nattokinase: Overview, Uses, Side Effects, Precautions, Interactions ...
News
doi: 10.3233/CH-211147. Park S, Kim CJ, Ha KC, et al. Efficacy and safety of aronia, red ginseng, shiitake mushroom, and nattokinase mixture on insulin ...