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BMC Med Genomics April 2021 PMID 33849530

Gene variants associated with acne vulgaris presentation and severity: a systematic review and meta-analysis.

Anna Hwee Sing Heng, Yee-How Say, Yang Yie Sio, Yu Ting Ng, Fook Tim Chew

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Mentions

14
Peak: 2 in Mar 2022
across 3 sources since Apr 2021

Extended reach

156,321
potential audience

Total likes

144

Video views

5,096

Mentions per month

Apr 2021 – Apr 2025

Where it's discussed

  • X / Twitter7 posts
  • News4 articles
  • YouTube3 videos

AI synopsis

What people are saying

The group exhibits a balanced view, with some posts emphasizing the role of genes such as TNF and CYP17A1 in acne severity, and others expressing anticipation for upcoming genetic research, using terms like 'potential for developing effective treatments' and 'future implications' that highlight both interest and perceived impact.

AgreementModerate agreement

Most discussions recognize the significance of genetic factors in acne, reflecting general support for the study's findings.

InterestModerate interest

Postings show a moderate level of curiosity, especially regarding specific gene influences like TNF and CYP17A1, indicating engagement with the topic.

EngagementModerate engagement

Participants reference ongoing research, technical terms, and future implications, demonstrating active interest and in-depth engagement.

ImpactModerate impact

The discussions hint at potential advancements in acne treatment and understanding, suggesting a positive outlook on the article’s influence.

Abstract in brief

  • The study reviews genetic factors linked to acne vulgaris, analyzing how different gene variants may influence its presentation and severity using data from 51 articles involving Asians and Caucasians.
  • The meta-analysis found that most gene variants showed no significant overall effect, but specific alleles in the TNF and CYP17A1 genes were associated with a reduced risk of both mild and severe acne, while the follistatin allele increased the risk slightly.
  • Additionally, the research identified 15 new single nucleotide polymorphisms (SNPs) in the 3' UTR region of the Toll-like Receptor 4 gene, which could be relevant for understanding acne genetics further.]
Read the full abstract

Top posts

Most liked on X and Bluesky
静岡皮膚科(2024年3月開業/静岡駅徒歩3分)院長　江畑慧
@shizuoka_doctor · X

@DM_pom_MD_PhD @OdaQ_DM @eajoymd 参考までに、近年はニキビの原因となるバリアントに関する研究がホットです。 代表的なものは、2018年のNature Communications誌の論文(https://t.co/4WVtlOmHyH)でしょうか。 今年のBMC Medical Genomics誌の論文(https://t.co/3lvUxJt090)もよくまとまっています。

Nov 30, 2021 · 16 likes · 4 shares · 129,109 followers View post →
BMC Series
@BMC_series · X

#BMCMedGenomics #GWAS #SystematicReview suggests that specific #genes act as risk variants for #acne presentation and severity. These include #TNF influencing inflammation - potential for developing effective treatments in future. Article link - https://t.co/GV2MSMKQNe https://t.co/kB8ceqFlYs

Aug 6, 2021 · 2 likes · 21,323 followers View post →
UNOrphen
@UNOrphen · X

RT @S96405539: @DM_pom_MD_PhD @OdaQ_DM @eajoymd 参考までに、近年はニキビの原因となるバリアントに関する研究がホットです。 代表的なものは、2018年のNature Communications誌の論文(https://t.co/…

Dec 19, 2021 · 4 shares · 449 followers View post →
robo_gwas
@robo_gwas · X

Gene variants associated with acne vulgaris presentation and severity: a systematic review and meta-analysis https://t.co/wHwUIiTx8g

Apr 14, 2021 · 169 followers View post →
お嬢さん
@eeiaamorainaki · X

RT @S96405539: @DM_pom_MD_PhD @OdaQ_DM @eajoymd 参考までに、近年はニキビの原因となるバリアントに関する研究がホットです。 代表的なものは、2018年のNature Communications誌の論文(https://t.co/…

May 16, 2022 · 4 shares · 130 followers View post →
ワイエス
@WyethYs · X

RT @S96405539: @DM_pom_MD_PhD @OdaQ_DM @eajoymd 参考までに、近年はニキビの原因となるバリアントに関する研究がホットです。 代表的なものは、2018年のNature Communications誌の論文(https://t.co/…

Feb 3, 2022 · 4 shares · 11 followers View post →

All mentions

Fook Tim Chew
@dbscft · X

Our earlier review on the genetic factors associated with the development of acne and it's severity. Looking forward to releasing our GWAS and functional chatacterization work from here on.. https://t.co/O114IshjZa

Jun 18, 2022 · 3 followers View post →
お嬢さん
@eeiaamorainaki · X

RT @S96405539: @DM_pom_MD_PhD @OdaQ_DM @eajoymd 参考までに、近年はニキビの原因となるバリアントに関する研究がホットです。 代表的なものは、2018年のNature Communications誌の論文(https://t.co/…

May 16, 2022 · 4 shares · 130 followers View post →
ワイエス
@WyethYs · X

RT @S96405539: @DM_pom_MD_PhD @OdaQ_DM @eajoymd 参考までに、近年はニキビの原因となるバリアントに関する研究がホットです。 代表的なものは、2018年のNature Communications誌の論文(https://t.co/…

Feb 3, 2022 · 4 shares · 11 followers View post →
UNOrphen
@UNOrphen · X

RT @S96405539: @DM_pom_MD_PhD @OdaQ_DM @eajoymd 参考までに、近年はニキビの原因となるバリアントに関する研究がホットです。 代表的なものは、2018年のNature Communications誌の論文(https://t.co/…

Dec 19, 2021 · 4 shares · 449 followers View post →
静岡皮膚科(2024年3月開業/静岡駅徒歩3分)院長　江畑慧
@shizuoka_doctor · X

@DM_pom_MD_PhD @OdaQ_DM @eajoymd 参考までに、近年はニキビの原因となるバリアントに関する研究がホットです。 代表的なものは、2018年のNature Communications誌の論文(https://t.co/4WVtlOmHyH)でしょうか。 今年のBMC Medical Genomics誌の論文(https://t.co/3lvUxJt090)もよくまとまっています。

Nov 30, 2021 · 16 likes · 4 shares · 129,109 followers View post →
BMC Series
@BMC_series · X

#BMCMedGenomics #GWAS #SystematicReview suggests that specific #genes act as risk variants for #acne presentation and severity. These include #TNF influencing inflammation - potential for developing effective treatments in future. Article link - https://t.co/GV2MSMKQNe https://t.co/kB8ceqFlYs

Aug 6, 2021 · 2 likes · 21,323 followers View post →
robo_gwas
@robo_gwas · X

Gene variants associated with acne vulgaris presentation and severity: a systematic review and meta-analysis https://t.co/wHwUIiTx8g

Apr 14, 2021 · 169 followers View post →