@MdBreathe Not that medical freedom... This medical freedom. You should come to @CannMedEvents in Puerto Rico this June. You'll meet many physicians who have witnessed extraordinary results with a drug safer than tylenol. https://t.co/PD4rlRiYwO https://t.co/vMvvBRrJtq https://t.co/wfKOeo3o9E
Trial of Psilocybin versus Escitalopram for Depression.
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Apr 2021 – Oct 2025Where it's discussed
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AI synopsis
What people are saying
Participants frequently reference the study’s findings, such as mentions that psilocybin was 'slightly more effective' or 'not significantly better' than escitalopram, and criticize or analyze its methodology, suggesting keen interest and engagement. The tone varies from cautious optimism to critical analysis, reflecting both curiosity and concern about the implications of the research for mental health treatments.
Most discussions acknowledge that the trial showed comparable results between psilocybin and escitalopram, with some viewing psilocybin as slightly more effective, reflecting general consensus.
The topic has high relevance for mental health treatment debates, attracting many comments, shares, and discussions about methodology and implications.
Participants reference specific study details, reanalyses, and commentary, indicating a deep engagement with the research findings.
The discussions highlight the significance of the trial's potential to influence future depression treatments, even if results are not drastically different.
Abstract in brief
- This study explored the antidepressant effects of psilocybin compared to the established treatment, escitalopram, in patients suffering from major depressive disorder over a 6-week period.
- Results showed that the psilocybin group had a greater reduction in depression scores and a higher percentage of patients achieving response and remission compared to the escitalopram group, although statistical significance was not reached.
- The findings suggest that psilocybin may be a promising alternative for treating depression, but further research is needed due to the small sample size and lack of significant differential outcomes.
Top posts
Most liked on X and BlueskyTbh, the current data already shows that. Check the supplement and the papers that came after (and will come soon). Look at the data not the editorially-controlled messaging. https://t.co/Z4leACnbuJ https://t.co/Y4cZhN6nk7
Psilocybin (magic mushrooms) was slightly more effective at treating depression than Escitalopram (a classic SSRI antidepressant) in a recent study. Psilocybin improved symptoms in 70% of patients compared to 48% of patients in the Escitalopram group. https://t.co/aOxVwG405y
マジックマッシュルームの化合物であるサイシロビンの治療効果を、従来の抗うつ薬と比較した第II相試験では、サイシロビンは抗うつ薬と同様に有効であり、即効性を認め、抗うつ薬に見られるような副作用も見られなかったようだ。 NEngl J Med 2021; 384:1402-1411 https://t.co/qtWyYMSOy0 https://t.co/tWaVH6kM0P
There's been a lot of buzz around Psilocybin use for depression. Click here for the latest research on mushrooms versus meds for depression
Buried in the supplement of our 2021 NEJM trial of psilocybin vs lexapro: https://t.co/d0BU8Zo5DM https://t.co/sKpMwBiM2N
All mentions
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It was a big deal when the NEJM released a paper comparing psilocybin Vs escitalopram but there was surprisingly little difference between the two interventions for depression. The same was true for personality. There…
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Unlock the potential of psilocybin therapy in this insightful video featuring Dr. Sulman Aziz Mirza. Explore the history, therapeutic effects, and safety of psilocybin for psychiatric disorders, and learn about its…
@henrymnyc Although a causal connection with schizotypy isn't clear e.g., https://t.co/ADqryizLEb And see also the changes in DSM-informed manic symptoms in the rich supplement here: https://t.co/d0BU8Zo5DM https://t.co/2xiOuzTFDt
RT @RCarhartHarris: I also like this self-constructed scale we developed for this trial. It feels relevant here. https://t.co/d0BU8Zo5DM ht…
RT @RCarhartHarris: I also like this self-constructed scale we developed for this trial. It feels relevant here. https://t.co/d0BU8Zo5DM ht…
I also like this self-constructed scale we developed for this trial. It feels relevant here. https://t.co/d0BU8Zo5DM https://t.co/JyAIKJMAC8 https://t.co/1vrNxs1dWx
@chchatham @zenbrainest I'm not sure it's a great marker. It's broadly relevant though. We also measured emotional intensity subjectively and saw it drop with lexapro but increase with psilocybin. That's in the rich supplement to the NEJM paper. https://t.co/d0BU8Zo5DM https://t.co/iKJrLT7XGl
RT @Kevin_McKernan: @MdBreathe Not that medical freedom... This medical freedom. You should come to @CannMedEvents in Puerto Rico this June…
RT @Kevin_McKernan: @MdBreathe Not that medical freedom... This medical freedom. You should come to @CannMedEvents in Puerto Rico this June…
RT @Kevin_McKernan: @MdBreathe Not that medical freedom... This medical freedom. You should come to @CannMedEvents in Puerto Rico this June…
RT @Kevin_McKernan: @MdBreathe Not that medical freedom... This medical freedom. You should come to @CannMedEvents in Puerto Rico this June…
RT @Kevin_McKernan: @MdBreathe Not that medical freedom... This medical freedom. You should come to @CannMedEvents in Puerto Rico this June…
@MdBreathe Not that medical freedom... This medical freedom. You should come to @CannMedEvents in Puerto Rico this June. You'll meet many physicians who have witnessed extraordinary results with a drug safer than tylenol. https://t.co/PD4rlRiYwO https://t.co/vMvvBRrJtq https://t.co/wfKOeo3o9E
@woodymatters https://t.co/GtK0vFToJk
RT @Kevin_McKernan: @CannMedEvents https://t.co/vMvvBRrJtq
RT @Kevin_McKernan: @CannMedEvents https://t.co/vMvvBRrJtq
RT @Kevin_McKernan: @CannMedEvents https://t.co/vMvvBRrJtq
RT @Kevin_McKernan: @CannMedEvents https://t.co/vMvvBRrJtq
@CannMedEvents https://t.co/vMvvBRrJtq
@elonmusk Magic mushrooms once a year!! Backed by science: https://t.co/kwcMpIZzvw
@LBCNews Why are #MagicMushrooms banned? Let people grow their own #MentalHealth medicine! #Psilocybin is just as effective as the gold standard for #DepressionTreatment! #LegalizePsilocybin #MentalHealthMatters #NaturalRemedies #EndStigma https://t.co/kwcMpIZzvw
@AAMortazavi @Drug_Researcher https://t.co/K6s3PWJhLx
RT @RCarhartHarris: Correction to: A Bayesian Reanalysis of a Trial of Psilocybin Versus Escitalopram for Depression by Nayak, et al. Psych…
@BjoornRa @Dag_Torp @IKolbeinsvik Også fase 2-studien på psilocybin mot depresjon var dobbelt-blindet, men igjen: Det er nesten umulig å unngå at blindingen brytes idet de psykoaktive effektene gjør seg merkbare. https://t.co/NwJVfNP88L
I used microdosing of psilocybin with lions mane & 500 mg nicotinic acid (vitamin B3) 3-4 days per week for over 200 days to titrate off Wellbutrin (not an SSRI, but an SNRI), & I don't have depression like I used to! Sunshine+Exercise helps too! https://t.co/Jl1fCu3CP6
元報告は投与後6週間の結果でしたが、今回は投与後6ヶ月の結果が報告されました。中度から重度のうつ病患者 59 名を対象に比較した結果、両治療グループとも治療後 6 か月までうつ症状が大幅に軽減したことがわかりました。さらに、シロシビンを服用したグループは、その期間にhttps://t.co/N7Sr26w7xH
RT @SMC_London: expert reaction to 6-month follow up of phase 2 trial of psilocybin versus escitalopram for depression https://t.co/X8JUgm5…
expert reaction to 6-month follow up of phase 2 trial of psilocybin versus escitalopram for depression | Science Media Centre https://t.co/FTv1Eyh1p9 #depression
RT @tommaso_barba: 2/ The study is the 6 month follow-up of the psilocybin vs escitalopram trial published in 2021 in the New England Journ…
2/ The study is the 6 month follow-up of the psilocybin vs escitalopram trial published in 2021 in the New England Journal of Medicine. Yes, this paper was long due to be published, sorry for the delay. https://t.co/mykIDyawy6
expert reaction to 6-month follow up of phase 2 trial of psilocybin versus escitalopram for depression https://t.co/X8JUgm5sAw
RT @RCarhartHarris: Correction to: A Bayesian Reanalysis of a Trial of Psilocybin Versus Escitalopram for Depression by Nayak, et al. Psych…
RT @RCarhartHarris: Correction to: A Bayesian Reanalysis of a Trial of Psilocybin Versus Escitalopram for Depression by Nayak, et al. Psych…
RT @RCarhartHarris: Correction to: A Bayesian Reanalysis of a Trial of Psilocybin Versus Escitalopram for Depression by Nayak, et al. Psych…
RT @RCarhartHarris: Correction to: A Bayesian Reanalysis of a Trial of Psilocybin Versus Escitalopram for Depression by Nayak, et al. Psych…
RT @RCarhartHarris: Correction to: A Bayesian Reanalysis of a Trial of Psilocybin Versus Escitalopram for Depression by Nayak, et al. Psych…
RT @RCarhartHarris: Correction to: A Bayesian Reanalysis of a Trial of Psilocybin Versus Escitalopram for Depression by Nayak, et al. Psych…
RT @RCarhartHarris: Correction to: A Bayesian Reanalysis of a Trial of Psilocybin Versus Escitalopram for Depression by Nayak, et al. Psych…
RT @RCarhartHarris: Correction to: A Bayesian Reanalysis of a Trial of Psilocybin Versus Escitalopram for Depression by Nayak, et al. Psych…
RT @RCarhartHarris: Correction to: A Bayesian Reanalysis of a Trial of Psilocybin Versus Escitalopram for Depression by Nayak, et al. Psych…
Correction to: A Bayesian Reanalysis of a Trial of Psilocybin Versus Escitalopram for Depression by Nayak, et al. Psychedelic Med 2023;1(1):18–26; doi: 10.1089/psymed.2022.0002 | Psychedelic Medicine https://t.co/JK0kWw1BnT
RT @RCarhartHarris: Tbh, the current data already shows that. Check the supplement and the papers that came after (and will come soon). Loo…
RT @RCarhartHarris: Tbh, the current data already shows that. Check the supplement and the papers that came after (and will come soon). Loo…
RT @RCarhartHarris: Tbh, the current data already shows that. Check the supplement and the papers that came after (and will come soon). Loo…
RT @RCarhartHarris: Tbh, the current data already shows that. Check the supplement and the papers that came after (and will come soon). Loo…
RT @RCarhartHarris: Tbh, the current data already shows that. Check the supplement and the papers that came after (and will come soon). Loo…
RT @RCarhartHarris: Tbh, the current data already shows that. Check the supplement and the papers that came after (and will come soon). Loo…
RT @RCarhartHarris: https://t.co/d0BU8Zo5DM
RT @RCarhartHarris: Tbh, the current data already shows that. Check the supplement and the papers that came after (and will come soon). Loo…
https://t.co/d0BU8Zo5DM https://t.co/vZ9tghsEgw
RT @RCarhartHarris: Tbh, the current data already shows that. Check the supplement and the papers that came after (and will come soon). Loo…
RT @RCarhartHarris: Tbh, the current data already shows that. Check the supplement and the papers that came after (and will come soon). Loo…
Tbh, the current data already shows that. Check the supplement and the papers that came after (and will come soon). Look at the data not the editorially-controlled messaging. https://t.co/Z4leACnbuJ https://t.co/Y4cZhN6nk7
RT @FutureJurvetson: OK, I'll point out the elephant in the appendix: Psilocybin crushes the SSRI standard of care for major depressive di…
/Surprisingly, the original trial found no difference between psilocybin and the SSRI on primary #depression outcome despite a study design that favored psilocybin (functional unblinding, recruitment bias, though not industry sponsorship) https://t.co/XWzy7W7hta
@RCarhartHarris Is it possible the 1mg psilocybin dose had an effect on the escitalopram group in "Trial of Psilocybin versus Escitalopram for Depression"? E.g. Moreno et al. (2006) found higher than expected effects from a very low dose of psilocybin (25ug/kg, or approx 2mg) on https://t.co/gjW3F9ug0C
RT @RCarhartHarris: Buried in the supplement of our 2021 NEJM trial of psilocybin vs lexapro: https://t.co/d0BU8Zo5DM https://t.co/sKpMwBiM…
RT @RCarhartHarris: Buried in the supplement of our 2021 NEJM trial of psilocybin vs lexapro: https://t.co/d0BU8Zo5DM https://t.co/sKpMwBiM…
RT @RCarhartHarris: Buried in the supplement of our 2021 NEJM trial of psilocybin vs lexapro: https://t.co/d0BU8Zo5DM https://t.co/sKpMwBiM…
RT @RCarhartHarris: Buried in the supplement of our 2021 NEJM trial of psilocybin vs lexapro: https://t.co/d0BU8Zo5DM https://t.co/sKpMwBiM…
RT @RCarhartHarris: Buried in the supplement of our 2021 NEJM trial of psilocybin vs lexapro: https://t.co/d0BU8Zo5DM https://t.co/sKpMwBiM…
Buried in the supplement of our 2021 NEJM trial of psilocybin vs lexapro: https://t.co/d0BU8Zo5DM https://t.co/sKpMwBiM2N
@JoylessRise @Slowtruths @_nukethewhales_ @ClarkeMicah @Dr_taniaspores https://t.co/i8sHviZjRn Imperial college's study showed that in terms of effectiveness psilocybin was at least as effective as normal antidepressants but with less of the negative side effects
With studies like this one, what should stop me from changing my pharma medication to mushroom medication? Anyone? https://t.co/OOIU6frSda
RT @FutureJurvetson: OK, I'll point out the elephant in the appendix: Psilocybin crushes the SSRI standard of care for major depressive di…
RT @FutureJurvetson: OK, I'll point out the elephant in the appendix: Psilocybin crushes the SSRI standard of care for major depressive di…
@smolderingwurm @DouthatNYT The article cites a comparative study that says it isn’t ‘much more effective’ than normal medications https://t.co/4sicd2tp7I
RT @psybalazs: This is a reanalysis of the escitalopram vs. psilocybin trial (https://t.co/sfZ2Q8v0Qj) considering baselines of expectancy…
This is a reanalysis of the escitalopram vs. psilocybin trial (https://t.co/sfZ2Q8v0Qj) considering baselines of expectancy and suggestibility. Unfortunately blinding integrity was not assessed, so we could not explore the interactions between blinding and expectancy.. next time!
Estudio realizado para comparar la eficacia de Psilocibina frente a uno de los mejores antidepresivos de actualidad: Escitalopram. Resultado: no hay una significativa diferencia. Cuidado con las modas y los charlatanes. Aquí el paper completo: https://t.co/4TV7OKY7GQ https://t.co/ZPVLWCTdTf
RT @niwoow_: 6주간 마법의 버섯 실로시빈Psilocybin 딱 2회 투여한게 항우울제인 에스시탈로프람Escitalopram 복용하는거랑 별 차이 없단 연구 Psilocybin versus Escitalopram for Depression…
@MariellyFlowers @DGDCUNAM Yo estoy contando lo que dice la evidencia científica. Aquí puedes ver algo de lo mucho que hay https://t.co/o3FKrR2wUQ
@f_hieronymus @FalteringlyOn @ProfDavidNutt I'd have to dive into the literature but do remember this from our head to head with psilocybin therapy (modest SHAPS change with SSRI): A lot of good stuff in the supplement: https://t.co/bYn0ZESGae https://t.co/3mXBzv1dYK
@PatrickSquirrel @tylerblack32 @elonmusk https://t.co/uy1gZRUAL5
RT @drmikehart: Psilocybin (magic mushrooms) was slightly more effective at treating depression than Escitalopram (a classic SSRI antidepre…
A Bayesian Reanalysis of a Trial of Psilocybin Versus Escitalopram for Depression | Psychedelic Medicine https://t.co/DAqZLvXrvt
RT @Mental_Elf: @DavidErritzoe @imperialcollege The 2nd study of depression & psilocybin conducted @imperialcollege by @DavidErritzoe, @Pro…
@DavidErritzoe @imperialcollege The 2nd study of depression & psilocybin conducted @imperialcollege by @DavidErritzoe, @ProfDavidNutt and colleagues compared psilocybin and a commonly used antidepressant, escitalopram #BAP2023 Full article
@asthouwilt @RCarhartHarris https://t.co/wUd86QpbC9
@mistman78 @unusual_whales Learned something new today. Article didn't mention addiction but psilocybin indeed helps with depression. https://t.co/qgkUk1cWN9
Didn't know the situation was this bad. What Jesse writes about, though, makes more sense of why the big-time RCTs in this space have been somewhat positive but hardly earth-shattering e.g., https://t.co/uFU8msC8GV https://t.co/96aZB5bgSL
The 9/3/2021 #JournalClub presented "Trial of Psilocybin versus Escitalopram for Depression". The recording is available free to all CPNP members. https://t.co/IB9C9oeBjA https://t.co/KcizRnNE3x
A Bayesian Reanalysis of a Trial of Psilocybin versus Escitalopram for Depression https://t.co/WYuaYpBS8q
https://t.co/WHnk4qt9t6
مقالات مفید، رفرنس های خوبی توشون پیدا میکنید و ایده خوبی بهتون میده کارهای آکادمیکِ به روز تو این حوزه چیکار میکنند: https://t.co/FiUiR0jRPs https://t.co/PrQuMimYME https://t.co/5Mu4IomAPf https://t.co/wZOqIxYdGa سایتهای مفید: https://t.co/lFYmRP7CsG https://t.co/ctZbjmiKxH
Brain-altering #fungi could lead the next frontier in mental health care @ConversationEDU https://t.co/xGsDAsmMEg https://t.co/hAevBiXu8B
RT @drmikehart: @hubermanlab Amazing. One interesting finding about the psilocybin vs. escitalopram study is that psilocybin was not compa…
RT @drmikehart: @hubermanlab Amazing. One interesting finding about the psilocybin vs. escitalopram study is that psilocybin was not compa…
@hubermanlab Amazing. One interesting finding about the psilocybin vs. escitalopram study is that psilocybin was not compared to "standard antidepressants"; it was compared to the best one. https://t.co/dNCCHMHx1w Escitalopram is the best anti-depressant. https://t.co/tNue72V8RV
RT @jwmares: A recent depression study compared (1) 2 sessions of psilocybin psychedelic therapy against (2) daily SSRI antidepressants +…
سیلۆسایبین لە SSRI کە لە ئێستایا باشترین دەرمانی دژە خەمۆکیە باشترە. تب: ئەو جۆرناڵە یەکێکە لە باشترین جۆرناڵەکانی پزیشکی. https://t.co/hwppsIa3Kb
RT @sulmoney:
RT @RCarhartHarris: https://t.co/bYn0ZESGae
https://t.co/bYn0ZESGae
RT @RCarhartHarris: Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/12M9dWmmfh
Latest in @NEJM
@thebandlab @sequencemyneuro Well, there is this: https://t.co/hNplZ5tetg
@zach_haigney That psilocybin therapy is 4x more effective than reuptake inhibitor antidepressants based on this from https://t.co/RFMivT7g8L or that it is equivalent to escitalopram from https://t.co/kgheoAybzq https://t.co/goK4iDhJRI
@girdley @AdamSinger Here's a start: https://t.co/z4KKhm7Ddf
Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/AeZ1O4b5Sv
RT @psybalazs: Really enjoyed @sdpnayak et al.'s (@bari_bilal @_fernando_rosas, @ExistWell, @RCarhartHarris) : "A Bayesian Reanalysis of a…
RT @psybalazs: Really enjoyed @sdpnayak et al.'s (@bari_bilal @_fernando_rosas, @ExistWell, @RCarhartHarris) : "A Bayesian Reanalysis of a…
RT @psybalazs: Really enjoyed @sdpnayak et al.'s (@bari_bilal @_fernando_rosas, @ExistWell, @RCarhartHarris) : "A Bayesian Reanalysis of a…
Really enjoyed @sdpnayak et al.'s (@bari_bilal @_fernando_rosas, @ExistWell, @RCarhartHarris) : "A Bayesian Reanalysis of a Trial of Psilocybin versus Escitalopram for Depression"
@guardiacivil psicodélicos vs medicamentos para la depresión https://t.co/jH9PxKw058 psicodélicos vs alcoholismo https://t.co/b4ZT3pDMIf https://t.co/hVKh7HS4Gi
@RianKMD if you look at fig1 of https://t.co/5Xj6aVC4UH, it is clear that the 1st dose contains ~90% of the efficacy; however the 3 weeks between doses is very low. My hunch is that 2-4 months breaks could be the sweat spot for repeated dosing where each dose has + effects
@maybeprobablyok @PortlandPolice https://t.co/62PECDDxBI
RT @AbudBakri: @BowTiedUM Non-inferiority proven https://t.co/eOLi9nJ7cT Why do the SSRI and destroy your penis if an alternative exists
@BowTiedUM Non-inferiority proven https://t.co/eOLi9nJ7cT Why do the SSRI and destroy your penis if an alternative exists
@lainternaa Con unos honguitos quedas, caimán https://t.co/uzOK1amktZ
Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/Qlsk39SvaA
@DavidJuurlink The trial didn't even compare psilocybin with placebo or other drugs. Not to mention the already mentioned very concerning adverse reactions. Previous trial that compared with escitalopram: https://t.co/SpA9NNLli1
RT @zenbrainest: A Bayesian Reanalysis of a Trial of Psilocybin Versus Escitalopram for Depression | Psychedelic Medicine https://t.co/MOL3…
A Bayesian Reanalysis of a Trial of Psilocybin Versus Escitalopram for Depression | Psychedelic Medicine https://t.co/MOL3Vfm99X
RT @RCarhartHarris: Neat collaboration
RT @RCarhartHarris: Neat collaboration
Neat collaboration
RT @drmikehart: Psilocybin (magic mushrooms) was slightly more effective at treating depression than Escitalopram (a classic SSRI antidepre…
RT @drmikehart: Psilocybin (magic mushrooms) was slightly more effective at treating depression than Escitalopram (a classic SSRI antidepre…
RT @blossomact: @PIMaastricht After a short break David Erritzoe & @m_wall of @Imperial_PRG are revisiting one of the most important psyche…
@PIMaastricht After a short break David Erritzoe & @m_wall of @Imperial_PRG are revisiting one of the most important psychedelic clinical trials to date https://t.co/sxZO00tuCO
Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/lewia3aSiV
@DrCMBurritt @CLOSLER @JHPsychedelics @N_Gukasyan @drjanaway @michaelpollan I see evidence for some real risk of adverse effects - but "immense destruction"? No - that statement doesn't appear to be grounded in the available evidence... https://t.co/iIPFIMzmaR https://t.co/Mu61Clc2Aw https://t.co/ZcULnDCSzd https://t.co/T8xnOMGj9V https://t.co/1ef1pGCyNr
@TomD60369895 Not at all unintelligent, what you propose is an option that's already being explored (eg. https://t.co/5Xj6aVC4UH).
RT @Innov_Medicine: Trial for Depression https://t.co/KzbBQcadOK 1. Did not show a significant difference in psilocybin vs. escitalopram.…
@JSoAbove Trial for Depression https://t.co/gzKc3m2dKW 1. Did not show a significant difference in psilocybin vs. escitalopram. 2. Generally favored psilocybin over escitalopram but lacked correction for multiple comparisons. 3. Longer trials: https://t.co/tLWWAPiBdx #meded #MedTwitter https://t.co/lDHLn9Dmyw
Trial for Depression https://t.co/KzbBQcadOK 1. Did not show a significant difference in psilocybin vs. escitalopram. 2. Generally favored psilocybin over escitalopram but lacked correction for multiple comparisons. 3. Longer trials: https://t.co/tLWWAP1ybx #meded #MedTwitte https://t.co/u4AAE55q2c
https://t.co/UuDPPwuVHv
Trial of Psilocybin versus Escitalopram for Depression https://t.co/h1qQqVvRPj
для последующего наблюдения за состоянием и проведение процедуры интеграции опыта специально подготовленным специалистом. Радует лишь одно - эффекты могут сохраняться в течение нескольких недель или даже месяцев после разовой процедуры. https://t.co/rnoqCHUPGH
RT @DrJamesCMorgan: @EricaCrompton @KatieConibear @sgdruffell @drrosalindwatts Good research too from @RCarhartHarris https://t.co/MsZW2ku…
@EricaCrompton @KatieConibear @sgdruffell @drrosalindwatts Good research too from @RCarhartHarris https://t.co/MsZW2ku21Q
@carlos_arnaud ¿Que piensa de la psilocibina? Tuvo un estudio de eficacia vs escitalopram el año anterior, dónde se encontró una eficacia similar. https://t.co/zD21v7HP78
Este me sorprendió muchísimo y terminé encontrando este estudio en @NEJM psilocibina vs escitalopram https://t.co/5QpapBtSBM https://t.co/g3EONK23Vg
@homemdosino @narguiles_ @holosheep_ https://t.co/Z3KfMsTZhh em breve em uma farmácia perto de voc6e
@LnpTruthLibrary Trial of Psilocybin versus Escitalopram for Depression (2021) https://t.co/gE22WIUhcA
Preprint time: “A Bayesian Reanalysis of a Trial of Psilocybin versus Escitalopram for Depression” A great showcase of the power of Bayes statistics for clinical trials, with open code & data. Grateful for being part of this fabulous collaboration lead by @sdpnayak.
A Bayesian Reanalysis of a Trial of Psilocybin versus Escitalopram for Depression https://t.co/TWh69pJ2vo
Trial of Psilocybin versus Escitalopram for Depression @RCarhartHarris Bruna Giribaldi, Rosalind Watts @drrosalindwatts, Michelle Baker-Jones, Ashleigh Murphy-Beiner @BeinerMurphy Roberta Murphy, @jonny__martell Allan Blemings @DavidErritzoe @ProfDavidNutt https://t.co/eKJzFit9R3
RT @SEPsiq: Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/7AKLqTfldL
Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/7AKLqTfldL
Seems that #psilocybin can work as well as an SSRI (or better). https://t.co/22f4wMToKD
The 9/3/2021 #JournalClub presented "Trial of Psilocybin versus Escitalopram for Depression". The recording is available free to all CPNP members. https://t.co/ET7aR3vagh https://t.co/PUmvcIXn3c
@EikoFried And this one specifically comparing escitalopram and psilocybin? https://t.co/bhqPHrPf31
@thirdwaveishere (1) The study the article is referring to is titled "Trial of Psilocybin versus Escitalopram for Depression" and had a psilocybin group of n=30. 1. They were investigating a completely different endpoint 2. With 30 participants can't be considered one of the largest
@EikoFried @court_wing https://t.co/mZUzafZbOB
RT @RCarhartHarris: Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/12M9dWmmfh
RT @RCarhartHarris: Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/12M9dWmmfh
RT @RCarhartHarris: Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/12M9dWmmfh
RT @RudolfUher: Psylocybin improved depression by 8 points, escitalopram by 6 points. Difference not significant. https://t.co/vbvTsBJZYE
An important standard in #medicalresearch is studies which directly compare an emerging therapeutic with an established treatment. This double-blind, #randomizedcontrolledtrial compares psilocybin and a common SSRI for depression. https://t.co/bAyAzJWFLL
RT @RCPsychPIPSIG: SSRIs vs Psilocybin for Depression, and interesting development https://t.co/I4sOBSd407
Also worth noting MADRS change here v similar to change on same measure in @RCarhartHarris psilocybin vs escitalopram trial https://t.co/xvUqC0nVPW - for better or worse planning the right outcome measure is crucial… still not obv to me if usu metrics rly describe psilocybin fx
The New England Journal of Medicine published a study on psilocybin for depression. Double blind, random, control trial vs Lexapro. Results were pretty close (which is huge) but also showed psilocybin crushed Lexapro on well-being. https://t.co/hGdRpyH1R4 https://t.co/Az2WHet1ZJ
RT @RCPsychPIPSIG: SSRIs vs Psilocybin for Depression, and interesting development https://t.co/I4sOBSd407
SSRIs vs Psilocybin for Depression, and interesting development https://t.co/I4sOBSd407
Our discussion with Dr. Robin Carhart-Harris is now up on YouTube! Learn more about his Trial of Psilocybin versus Escitalopram for Depression, and his thoughts on the future of psilocybin research. @RCarhartHarris #PsilocybinResearch https://t.co/gOwU9knvmw
Trial of Psilocybin versus Escitalopram for Depression | NEJM - no significant difference in antidepressant effects between psilocybin and escitalopram https://t.co/BqCSrqML8w
RT @RCarhartHarris: Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/12M9dWmmfh
RT @ViewsOnDrugsBot: Trial of #Psilocybin versus Escitalopram for #Depression https://t.co/oigh75AGPL
Pues bien, hace apenas semanas se ha publicado que la psilocibina sería, como mínimo, tan buen tratamiento como el estándar dorado para la depresión. https://t.co/B5vOOBkqw9
RT @RCarhartHarris: Grateful for my many wonderful colleagues❤️ over the years in the @Imperial_PRG and for the philanthropic support that…
Grateful for my many wonderful colleagues❤️ over the years in the @Imperial_PRG and for the philanthropic support that kept me in work, allowed the @Imperial_PRG to happen & contributions like this: https://t.co/3DFtYmAWQf
RT @Kevin_McKernan: @tientekens There are safer alternatives. https://t.co/CQtOuFYoFu
@tientekens There are safer alternatives. https://t.co/CQtOuFYoFu
RT @RCarhartHarris: Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/12M9dWmmfh
RT @RCarhartHarris: Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/12M9dWmmfh
RT @madras_bertha: Trial of Psilocybin versus Escitalopram for Depression - PubMed No clear winner https://t.co/lDcrv0K9to
Trial of Psilocybin versus Escitalopram for Depression - PubMed No clear winner https://t.co/lDcrv0K9to
RT @bengreenfield: There's been a lot of buzz around Psilocybin use for depression. Click here for the latest research on mushrooms versus…
RT @bengreenfield: There's been a lot of buzz around Psilocybin use for depression. Click here for the latest research on mushrooms versus…
RT @bengreenfield: There's been a lot of buzz around Psilocybin use for depression. Click here for the latest research on mushrooms versus…
RT @bengreenfield: There's been a lot of buzz around Psilocybin use for depression. Click here for the latest research on mushrooms versus…
RT @bengreenfield: There's been a lot of buzz around Psilocybin use for depression. Click here for the latest research on mushrooms versus…
There's been a lot of buzz around Psilocybin use for depression. Click here for the latest research on mushrooms versus meds for depression
❇️ انقلابی در #درمان_افسردگی [Psilocybin]
RT @RCarhartHarris: Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/12M9dWmmfh
Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/kRsfrPz6Ny
Trial of Psilocybin versus Escitalopram for Depression Robin Carhart-Harris, Ph.D., et al.
Trial of Psilocybin versus Escitalopram for Depression https://t.co/0X2QSLqBg2
RT @CarlatPsych: Everyone got psilocyin in this new #depression trial from NEJM, but the treatment group got a full dose +placebo and the c…
Trial of Psilocybin versus Escitalopram for Depression | NEJM via /r/science https://t.co/mYRrw1zKEN
RT @RCarhartHarris: Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/12M9dWmmfh
Everyone got psilocyin in this new #depression trial from NEJM, but the treatment group got a full dose +placebo and the control group got a mini dose + excitalopram. A clever way to disguise the blind. Result: #psilocybin = escitalopram https://t.co/E1CSxCHjNX https://t.co/Jds1d1ermk
RT @RCarhartHarris: Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/12M9dWmmfh
Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/nDOMM8ColV
@billmaher @RealTimers The study actually showed that it was no better than an common antidepressant not better. but the skit was great Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/q6WWhYXf0m
RT @drugSciBot: Trial of #Psilocybin versus Escitalopram for #Depression https://t.co/oigh75AGPL
Trial of #Psilocybin versus Escitalopram for #Depression https://t.co/oigh75AGPL
RT @RudolfUher: Psylocybin improved depression by 8 points, escitalopram by 6 points. Difference not significant. https://t.co/vbvTsBJZYE
RT @JoeKennedyEM: FYI @acmtmedtox med tox fellows: Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/QS83xSTb2P
RT @MrJeffKarp: Trial of Psilocybin versus Escitalopram for Depression https://t.co/jKmkEwRIUF
FYI @acmtmedtox med tox fellows: Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/QS83xSTb2P
Data vs spin: commentary on “Trial of Psilocybin versus Escitalopram for Depression” https://t.co/v9jPQWEVSO
RT @RudolfUher: Psylocybin improved depression by 8 points, escitalopram by 6 points. Difference not significant. https://t.co/vbvTsBJZYE
An interesting & refreshing look at current anti-depressants & the need for new approaches; Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/PO6u5W5AJi
RT @RudolfUher: Psylocybin improved depression by 8 points, escitalopram by 6 points. Difference not significant. https://t.co/vbvTsBJZYE
RT @RudolfUher: Psylocybin improved depression by 8 points, escitalopram by 6 points. Difference not significant. https://t.co/vbvTsBJZYE
Trial of Psilocybin versus Escitalopram for Depression https://t.co/gBaiA65jp7
Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/xIp3TwjSbV NEJMにシロシビンと鬱のP2試験出てた。プライマリエンドポイントはメットしなかったのね。セカンダリは良い傾向だけど多重解析の問題ありと。
Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/ky9KwphfJH
Cuando un producto sicodélico iguale el efecto de un antidepresivo clásico, no deberías extrañarte... Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/VNdshhfWvz
RT @RCarhartHarris: Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/12M9dWmmfh
Psylocybin improved depression by 8 points, escitalopram by 6 points. Difference not significant. https://t.co/vbvTsBJZYE
Trial of #Psilocybin versus Escitalopram for #Depression https://t.co/CQ5CiaoEgs @RCarhartHarris continuing to set the standard for research involving psychedelics. The future is fungi.
Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/pxzfof2Nsl
RT @RCarhartHarris: Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/12M9dWmmfh
Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/z0Vk5tXDC0
Trial of Psilocybin versus Escitalopram for Depression Seems good but perhaps not remarkable here compared to SMILES diet trial results. https://t.co/gfhxYh6nWR
Trial of Psilocybin versus Escitalopram for Depression https://t.co/NYcZr1qD19
#94 Comparaison ISRS vs psilocybine, non significatif sur le critère de jugement principal mais très encourageant #onepaperadaychallenge https://t.co/ZtjNd9ssyD
Abstract here: https://t.co/EnTppiLUaa
RT @court_wing: “Data vs spin: commentary on “Trial of Psilocybin versus Escitalopram for Depression”. Some surprisingly revealing language…
“Data vs spin: commentary on “Trial of Psilocybin versus Escitalopram for Depression”. Some surprisingly revealing language from @RCarhartHarris on data in psilocybin vs SSRI study. Crucial reading to understand profound implications of its results https://t.co/hQRyJogik6
RT @leafs_s: Trial of Psilocybin versus Escitalopram for Depression https://t.co/YOpMOFQ9aj
Trial of Psilocybin versus Escitalopram for Depression https://t.co/YOpMOFQ9aj
RT @RCarhartHarris: Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/12M9dWmmfh
RT @RCarhartHarris: Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/12M9dWmmfh
Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/Zj1TYrGcHZ
Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/lZBl3fATjg
RT @RCarhartHarris: Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/12M9dWmmfh
https://t.co/9xo0XY4GbL #Trial of #Psilocybin versus #Escitalopram for #Depression
RT @RCarhartHarris: Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/12M9dWmmfh
RT @dronita_de: Trial of Psilocybin versus Escitalopram for Depression | NEJM https://t.co/ri0ESoCqQG #DHPSP #Psilocybin #Escitalopram #D…
RT @drmikehart: I agree. Author's conclusions: "did not show a significant difference in antidepressant effects between psilocybin and es…
I agree. Author's conclusions: "did not show a significant difference in antidepressant effects between psilocybin and escitalopram." But an increase in 8 points vs. 6 points on QIDS-SR-16 and 22% difference in remission IS significant. https://t.co/aOxVwG405y https://t.co/M0L47Ejue5
RT @drmikehart: Psilocybin (magic mushrooms) was slightly more effective at treating depression than Escitalopram (a classic SSRI antidepre…
RT @drmikehart: Psilocybin (magic mushrooms) was slightly more effective at treating depression than Escitalopram (a classic SSRI antidepre…
In other news Magic Mushrooms still looking like potentially like an alternative to SSRIs. Trial of Psilocybin versus Escitalopram for Depression | NEJM
RT @APRA_bot: Trial of Psilocybin versus Escitalopram for Depression https://t.co/lYG7KJtCMC
Trial of Psilocybin versus Escitalopram for Depression. https://t.co/U7UvDevlq8
RT @ichiipsy: マジックマッシュルームの化合物であるサイシロビンの治療効果を、従来の抗うつ薬と比較した第II相試験では、サイシロビンは抗うつ薬と同様に有効であり、即効性を認め、抗うつ薬に見られるような副作用も見られなかったようだ。 NEngl J Med 2021…
RT @drmikehart: Psilocybin (magic mushrooms) was slightly more effective at treating depression than Escitalopram (a classic SSRI antidepre…
RT @drmikehart: Psilocybin (magic mushrooms) was slightly more effective at treating depression than Escitalopram (a classic SSRI antidepre…
RT @drmikehart: Psilocybin (magic mushrooms) was slightly more effective at treating depression than Escitalopram (a classic SSRI antidepre…
RT @ichiipsy: マジックマッシュルームの化合物であるサイシロビンの治療効果を、従来の抗うつ薬と比較した第II相試験では、サイシロビンは抗うつ薬と同様に有効であり、即効性を認め、抗うつ薬に見られるような副作用も見られなかったようだ。 NEngl J Med 2021…
RT @drmikehart: Psilocybin (magic mushrooms) was slightly more effective at treating depression than Escitalopram (a classic SSRI antidepre…
RT @drmikehart: Psilocybin (magic mushrooms) was slightly more effective at treating depression than Escitalopram (a classic SSRI antidepre…
Alright psilocybin! https://t.co/Q6RhTvqRPX
RT @drmikehart: Psilocybin (magic mushrooms) was slightly more effective at treating depression than Escitalopram (a classic SSRI antidepre…
RT @drmikehart: Psilocybin (magic mushrooms) was slightly more effective at treating depression than Escitalopram (a classic SSRI antidepre…
Trial of Psilocybin versus Escitalopram for Depression https://t.co/lYG7KJtCMC
RT @drmikehart: Psilocybin (magic mushrooms) was slightly more effective at treating depression than Escitalopram (a classic SSRI antidepre…
RT @drmikehart: Psilocybin (magic mushrooms) was slightly more effective at treating depression than Escitalopram (a classic SSRI antidepre…
RT @drmikehart: Psilocybin (magic mushrooms) was slightly more effective at treating depression than Escitalopram (a classic SSRI antidepre…
Psilocybin (magic mushrooms) was slightly more effective at treating depression than Escitalopram (a classic SSRI antidepressant) in a recent study. Psilocybin improved symptoms in 70% of patients compared to 48% of patients in the Escitalopram group. https://t.co/aOxVwG405y
RT @ichiipsy: マジックマッシュルームの化合物であるサイシロビンの治療効果を、従来の抗うつ薬と比較した第II相試験では、サイシロビンは抗うつ薬と同様に有効であり、即効性を認め、抗うつ薬に見られるような副作用も見られなかったようだ。 NEngl J Med 2021…
RT @psytyfi: The New England Journal of Medicinessä julkaistiin eilen tuloksia ensimmäisestä tutkimuksesta, jossa psykedeelin vaikuttavuutt…
The New England Journal of Medicinessä julkaistiin eilen tuloksia ensimmäisestä tutkimuksesta, jossa psykedeelin vaikuttavuutta masennuksen hoidossa verrattiin SSRI-lääkkeeseen. 1/ https://t.co/ViFwie1rj8
RT @ichiipsy: マジックマッシュルームの化合物であるサイシロビンの治療効果を、従来の抗うつ薬と比較した第II相試験では、サイシロビンは抗うつ薬と同様に有効であり、即効性を認め、抗うつ薬に見られるような副作用も見られなかったようだ。 NEngl J Med 2021…
RT @ichiipsy: マジックマッシュルームの化合物であるサイシロビンの治療効果を、従来の抗うつ薬と比較した第II相試験では、サイシロビンは抗うつ薬と同様に有効であり、即効性を認め、抗うつ薬に見られるような副作用も見られなかったようだ。 NEngl J Med 2021…
RT @ichiipsy: マジックマッシュルームの化合物であるサイシロビンの治療効果を、従来の抗うつ薬と比較した第II相試験では、サイシロビンは抗うつ薬と同様に有効であり、即効性を認め、抗うつ薬に見られるような副作用も見られなかったようだ。 NEngl J Med 2021…
RT @ichiipsy: マジックマッシュルームの化合物であるサイシロビンの治療効果を、従来の抗うつ薬と比較した第II相試験では、サイシロビンは抗うつ薬と同様に有効であり、即効性を認め、抗うつ薬に見られるような副作用も見られなかったようだ。 NEngl J Med 2021…
RT @ichiipsy: マジックマッシュルームの化合物であるサイシロビンの治療効果を、従来の抗うつ薬と比較した第II相試験では、サイシロビンは抗うつ薬と同様に有効であり、即効性を認め、抗うつ薬に見られるような副作用も見られなかったようだ。 NEngl J Med 2021…
RT @ichiipsy: マジックマッシュルームの化合物であるサイシロビンの治療効果を、従来の抗うつ薬と比較した第II相試験では、サイシロビンは抗うつ薬と同様に有効であり、即効性を認め、抗うつ薬に見られるような副作用も見られなかったようだ。 NEngl J Med 2021…
RT @ichiipsy: マジックマッシュルームの化合物であるサイシロビンの治療効果を、従来の抗うつ薬と比較した第II相試験では、サイシロビンは抗うつ薬と同様に有効であり、即効性を認め、抗うつ薬に見られるような副作用も見られなかったようだ。 NEngl J Med 2021…
マジックマッシュルームの化合物であるサイシロビンの治療効果を、従来の抗うつ薬と比較した第II相試験では、サイシロビンは抗うつ薬と同様に有効であり、即効性を認め、抗うつ薬に見られるような副作用も見られなかったようだ。 NEngl J Med 2021; 384:1402-1411 https://t.co/qtWyYMSOy0 https://t.co/tWaVH6kM0P
Trial of Psilocybin versus Escitalopram for Depression | NEJM https://www.nejm.org/doi/full/10.1056/NEJMoa2032994#.YHfn4SeYiX9.twitter
Trial of Psilocybin versus Escitalopram for Depression https://t.co/BojSP12rzZ
https://www.nejm.org/doi/suppl/10.1056/NEJMoa2032994/suppl_file/nejmoa2032994_appendix.pdf
RH