Int J Dermatol August 2021 PMID 33871071

Combination of topical and oral glutathione as a skin-whitening agent: a double-blind randomized controlled clinical trial.

Siswanto Wahab, Anis I Anwar, Andi N Zainuddin, Emma N Hutabarat, Asvina A Anwar, Ivan Kurniadi

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Mentions

Peak: 2 in Apr 2021

across 3 sources since Apr 2021

Extended reach

257,973

potential audience

Total likes

4,736

Video views

257,781

Mentions per month

Apr 2021 – Mar 2025

Where it's discussed

X / Twitter4 posts
YouTube2 videos
News2 articles

AI synopsis

What people are saying

Many discussions mention the combined use of topical and oral glutathione, with phrases like 'more effective' and 'significant results,' indicating interest in the potential benefits. However, users also question whether these findings will lead to real-world changes, reflecting a cautious attitude and moderate engagement with the research's implications.

AgreementNeither agree nor disagree

Discussions are mixed; some posts accept the findings, while others question their significance or methodology.

InterestModerate interest

Most discussions show moderate interest, with some users intrigued by the potential skin-lightening effects, but few deeply explore technical details.

EngagementModerate engagement

Comments include references to the study's methods and implications, indicating a moderate level of engagement.

ImpactNeutral impact

The overall tone suggests limited recognition of a major breakthrough, but some users see potential influence in skincare trends.

Abstract in brief

The study investigated whether combining topical and oral glutathione is more effective for skin whitening than using either method alone, finding that the combination showed significantly better results.
Conducted on 46 participants over 8 weeks, the trial used colorimetric measurements to assess skin lightening, with groups receiving either placebo or glutathione in oral and topical forms.
Results indicated that the combination therapy led to the greatest reduction in melanin index and L score, suggesting that using both topical and oral glutathione could be a more effective skin-whitening approach compared to monotherapy.]

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All mentions

Enhanced Skin Whitening with Combined Topical and Oral Glutathione Treatment

This study explores the effectiveness of combining topical and oral glutathione for skin whitening, showing significantly better results than using either method alone over an 8-week period.

ingck · Mar 9, 2025 201,815 views

Effectiveness of Combined Oral and Topical Glutathione for Skin Lightening

The study investigates whether combining topical and oral glutathione is more effective for skin whitening than using either method alone. Results showed significantly better skin lightening with the combination therapy…

Discover Dermatology · Feb 24, 2023 55,967 views

Pee_lanwat

@Chantanawat · X

Mar 9, 2025 · 75 followers View post →

のめりこみ

@CHUKIBOKAKURAN · X

Nov 29, 2021 · 10 followers View post →

Public Health Bulletin

@BulletinPublic · X

Combination of topical and oral glutathione as a skin-whitening agent: a double-blind randomized controlled clinical trial. https://t.co/XKlR8QR3Bq

Apr 21, 2021 · 19 followers View post →

dermatologyf

@dermatologyf · X

Combination of topical and oral glutathione as a skin-whitening agent: a double-blind randomized controlled clinical trial https://t.co/v9gqSruhmc

Apr 21, 2021 · 89 followers View post →