Habitual coffee drinkers display a distinct pattern of brain functional connectivity.

Ricardo Magalhães, Maria Picó-Pérez, Madalena Esteves, Rita Vieira, Teresa C Castanho, Liliana Amorim, Mafalda Sousa, Ana Coelho, Henrique M Fernandes, Joana Cabral, Pedro S Moreira, Nuno Sousa

November 2021 Mol Psychiatry

Synopsis of Social media discussions

Many posts touch on the key findings of the publication, such as its connection to stress and anxiety, with comments like 'higher consumption of coffee... has an impact on brain functional connectivity' and queries like 'should I stop drinking so much coffee??'. The tone of these discussions ranges from inquisitive to slightly worried, highlighting a mix of irony and seriousness that suggests both concern and a desire for further information on the topic.

A
Agreement
 Moderate agreement

Many posts reflect an understanding and acceptance of the findings from the study, although a few express uncertainty about its implications.

I
Interest
 High level of interest

There is a high level of curiosity about how coffee consumption affects brain function, as seen through numerous mentions and references to additional resources regarding the topic.

E
Engagement
 Moderate level of engagement

While some discussions are brief, several participants delve into related research and personal anecdotes, indicating a moderate level of engagement.

I
Impact
 High level of impact

Users are concerned about the study's implications on their coffee consumption and mental health, suggesting that they see it as having potential long-lasting effects.

Social Mentions

YouTube

2 Videos

Facebook

4 Posts

Twitter

102 Posts

Blogs

5 Articles

News

58 Articles

Reddit

3 Posts

Metrics

Video Views

978,849

Total Likes

17,863

Extended Reach

2,926,011

Social Features

174

Timeline: Posts about article

Top Social Media Posts

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  • P IbarraRazo
    @ben_leshem (Twitter)

    RT @docmanjarrez: @lajornadaonline agalhães, R., Picó-Pérez, M., Esteves, M. et al. Habitual coffee drinkers display a distinct pattern of…
    view full post

    August 9, 2025

    1

  • Manjarrez-Gutiérrez L.
    @docmanjarrez (Twitter)

    @lajornadaonline agalhães, R., Picó-Pérez, M., Esteves, M. et al. Habitual coffee drinkers display a distinct pattern of brain functional connectivity. Mol Psychiatry 26, 6589–6598 (2021). https://t.co/jdG5PPlxhI
    view full post

    August 7, 2025

    5

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  • Dr. Gennadi Glinsky, MD, Ph.D.
    @gglinskii (Twitter)

    Habitual coffee drinkers display a distinct pattern of brain functional connectivity https://t.co/Gy4l262NaF
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    June 8, 2025

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    Wszystkie odcinki bardzo ciekawe i warte posłuchania!
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  • Mimi di Rosa
    @MimidiRosa1 (Twitter)

    RT @meccanismo: «the effects of [caffeine/coffee] chronic consumption on the brain’s intrinsic functional networks are still largely unknow…
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    July 8, 2021

    5

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    @nickbluebox (Twitter)

    RT @meccanismo: «the effects of [caffeine/coffee] chronic consumption on the brain’s intrinsic functional networks are still largely unknow…
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    July 8, 2021

    5

  • Riccardo C. Gatti
    @RiccardoGatti (Twitter)

    RT @meccanismo: «the effects of [caffeine/coffee] chronic consumption on the brain’s intrinsic functional networks are still largely unknow…
    view full post

    July 8, 2021

    5

  • acino2020
    @acino2020 (Twitter)

    RT @meccanismo: «the effects of [caffeine/coffee] chronic consumption on the brain’s intrinsic functional networks are still largely unknow…
    view full post

    July 8, 2021

    5

  • Giuliano Gavazzi
    @meccanismo (Twitter)

    «the effects of [caffeine/coffee] chronic consumption on the brain’s intrinsic functional networks are still largely unknown» eppure non si sente parlare di principi di precauzione... https://t.co/PhBPkGEgGx
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    July 8, 2021

    7

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  • Rina Saltman
    @rinatie_ceo (Twitter)

    Habitual coffee drinkers display a distinct pattern of brain functional connectivity \ｺﾋｯ/ ☕️ https://t.co/qiWyC2Nk0G
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    May 24, 2021

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    @magnivili (Twitter)

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    @ale_lach (Twitter)

    Habitual coffee drinkers display a distinct pattern of brain functional connectivity and higher stress levels https://t.co/7qJ0ky3JeT
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    May 8, 2021

    2

  • Eino-Mikael Talvitie
    @EinoMikael (Twitter)

    RT @MicTott: Habitual coffee drinkers display a distinct pattern of brain functional connectivity and reported higher levels of anxiety and…
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    May 8, 2021

    6

  • Anna M Tartaglione
    @AMTartaglione (Twitter)

    RT @MicTott: Habitual coffee drinkers display a distinct pattern of brain functional connectivity and reported higher levels of anxiety and…
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    May 7, 2021

    6

  • Samuel Montero-Hernandez
    @s_monterohdz (Twitter)

    RT @MicTott: Habitual coffee drinkers display a distinct pattern of brain functional connectivity and reported higher levels of anxiety and…
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    May 6, 2021

    6

  • Andrew Zalesky
    @AndrewZalesky (Twitter)

    RT @MicTott: Habitual coffee drinkers display a distinct pattern of brain functional connectivity and reported higher levels of anxiety and…
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    May 6, 2021

    6

  • Wei Cheng
    @WeiFDU (Twitter)

    RT @MicTott: Habitual coffee drinkers display a distinct pattern of brain functional connectivity and reported higher levels of anxiety and…
    view full post

    May 6, 2021

    6

  • Michael Totty
    @MicTott (Twitter)

    Habitual coffee drinkers display a distinct pattern of brain functional connectivity and reported higher levels of anxiety and stress - uh oh, should I stop drinking so much coffee?? https://t.co/cpItNJrPm1
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    May 6, 2021

    33

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  • Dr Carol Granger
    @CarolGranger2 (Twitter)

    Magalhães, R., Picó-Pérez, M., Esteves, M. et al. Habitual coffee drinkers display a distinct pattern of brain functional connectivity. Mol Psychiatry (2021). https://t.co/D7YoMa7IZJ. https://t.co/sfXVoBtL1c
    view full post

    April 30, 2021

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  • el borincano
    @ger_Kreuz (Twitter)

    Habitual coffee drinkers display a distinct pattern of brain functional connectivity #Coffee is the most widely consumed source of caffeine worldwide, partly due to the psychoactive effects of this #methylxanthine. https://t.co/viZ0vV3xKM
    view full post

    April 30, 2021

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    @48nairda (Twitter)

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    April 30, 2021

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  • Mihai Hristea
    @MihaiHristea (Twitter)

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    April 30, 2021

    2

  • Camil Stoenescu
    @camilstoenescu (Twitter)

    Habitual coffee drinkers display a distinct pattern of brain functional connectivity. https://t.co/rjCohWczHZ
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    April 30, 2021

    1

    2

  • Deluxe Dog
    @deluxedog6 (Twitter)

    Habitual coffee drinkers display a distinct pattern of brain functional connectivity via /r/Nootropics https://t.co/CmoGUMt2gQ
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    April 30, 2021

  • Ben Hagan
    @ben_hagan (Twitter)

    Habitual coffee drinkers display a distinct pattern of brain functional connectivity | Molecular Psychiatry https://t.co/teouVRJrv0
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    April 29, 2021

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    @neuroreddit (Twitter)

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    April 29, 2021

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    @NootropicReddit (Twitter)

    Habitual coffee drinkers display a distinct pattern of brain functional connectivity via /r/Nootropics https://t.co/shbBcQWZtt
    view full post

    April 28, 2021


  • @SocialChatsSF (Twitter)

    Habitual coffee drinkers display a distinct pattern of brain functional connectivity - via @nature #MolecularPsychiatry https://t.co/dTSt5bk6Qb
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    April 28, 2021

  • ريهام الصَيدلاني.
    @AlsaidlaniReham (Twitter)

    RT @SustainHistory: Habitual #coffee drinkers display a distinct pattern of #brain #functional #connectivity higher consumption caffeinate…
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    April 27, 2021

    5

  • Bader Allahyani بدر اللحياني
    @bdrallahyani (Twitter)

    RT @SustainHistory: Habitual #coffee drinkers display a distinct pattern of #brain #functional #connectivity higher consumption caffeinate…
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    April 27, 2021

    5

  • عبدالله الحياني
    @dr_alhayani (Twitter)

    RT @SustainHistory: Habitual #coffee drinkers display a distinct pattern of #brain #functional #connectivity higher consumption caffeinate…
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    April 27, 2021

    5

  • Nayef Al-Rodhan
    @SustainHistory (Twitter)

    Habitual #coffee drinkers display a distinct pattern of #brain #functional #connectivity higher consumption caffeinated products has an impact in brain functional connectivity at rest with implications in #emotionality, #alertness & readiness to #action https://t.co/jJMjOVOlO3
    view full post

    April 27, 2021

    8

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  • Sitearm
    @Sitearm (Twitter)

    Habitual coffee drinkers display a distinct pattern of brain functional connectivity - /psychoactive effects of methylxanthine/ sample size 31 coffee drinkers, 24 non-coffee drinkers /institute research study backed by six global coffee companies/ https://t.co/ytKym7iqMH
    view full post

    April 26, 2021

  • Hot Science Balloon
    @hotsciballoon (Twitter)

    Nutshell #251: Recent neuroimaging study in the evaluation of habitual coffee drinkers showed that caffeine may lead to decreased functional connectivity in somatosensory and limbic brain networks. https://t.co/oikNcwzFzE
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    April 26, 2021

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  • RRID Robot
    @RobotRrid (Twitter)

    RRIDs were included in the Molecular Psychiatry paper "Habitual coffee drinkers display a distinct patter…" (https://t.co/gCALNTdSyu). Thank you for making your #methodsmatter. #RRID
    view full post

    April 25, 2021


  • @hayleysacommie (Twitter)

    https://t.co/YOmMnH2wlO Ahhh shit, need to cut the coffee a little, but also *hears old professor whispering* "correlation doesn't equal causation."
    view full post

    April 22, 2021

  • Winsome Martin
    @compro_tax (Twitter)

    Habitual coffee drinkers display a distinct pattern of brain functional connectivity https://t.co/OYZoecA2v0
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    April 22, 2021

  • Jose
    @Jose_8523 (Twitter)

    RT @ExphysPhD: Higher consumption of coffee and caffeinated products has an impact in brain functional connectivity at rest with implicatio…
    view full post

    April 22, 2021

    7

  • Cindy Kugler
    @Exspec85 (Twitter)

    RT @ExphysPhD: Higher consumption of coffee and caffeinated products has an impact in brain functional connectivity at rest with implicatio…
    view full post

    April 22, 2021

    7

  • Jose Antonio PhD
    @JoseAntonioPhD (Twitter)

    RT @ExphysPhD: Higher consumption of coffee and caffeinated products has an impact in brain functional connectivity at rest with implicatio…
    view full post

    April 22, 2021

    7

  • Jeffrey R. Stout
    @ExphysPhD (Twitter)

    Higher consumption of coffee and caffeinated products has an impact in brain functional connectivity at rest with implications in emotionality, alertness, and readiness to action. https://t.co/eoimn0w9rG
    view full post

    April 22, 2021

    28

    7

  • Paul McCullough
    @ThePostsynaptic (Twitter)

    Habitual coffee drinkers display a distinct pattern of brain functional connectivity https://t.co/8Gj6pbWf7S https://t.co/Jc9ZMDlikK
    view full post

    April 21, 2021

  • graham music
    @grahammusic1 (Twitter)

    cant tell if good or bad .. but perhaps the coffee's fault . Habitual coffee drinkers display a distinct pattern of brain functional connectivity https://t.co/K3CpiH5dab via @NewsNowUK
    view full post

    April 20, 2021

  • Darryl Howery
    @dghowery (Twitter)

    Habitual coffee drinkers display a distinct pattern of brain functional connectivity #coffee https://t.co/zYIIpgC0UX
    view full post

    April 19, 2021

  • Ben Pitts Nashville
    @NashSpaceBroker (Twitter)

    Habitual coffee drinkers display a distinct pattern of brain functional connectivity https://t.co/eBMXtdX5g5
    view full post

    April 19, 2021

  • Pepe Muñoz
    @PepeMunoz1 (Twitter)

    Habitual coffee drinkers display a distinct pattern of brain functional connectivity https://t.co/42ncUfF7m3
    view full post

    April 19, 2021

Abstract Synopsis

  • Coffee is the most widely consumed source of caffeine, but its effects on brain networks from chronic use are not well understood.
  • This study analyzed the resting brain activity of habitual coffee drinkers (CD) and non-coffee drinkers (NCD), revealing that CD had decreased connectivity in certain brain networks related to sensory and emotional processing.
  • Increased frequency of caffeine consumption was linked to higher stress and anxiety levels, indicating that coffee drinking affects brain function and emotional states.