PubHawk
Front Cell Infect Microbiol May 2021 PMID 33889552

IgA Antibodies and IgA Deficiency in SARS-CoV-2 Infection.

Isabella Quinti, Eva Piano Mortari, Ane Fernandez Salinas, Cinzia Milito, Rita Carsetti

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Mentions

44
Peak: 6 in Jul 2021
across 3 sources since Apr 2021

Extended reach

158,268
potential audience

Total likes

916

Video views

28,308

Mentions per month

Apr 2021 – Jun 2023

Where it's discussed

  • X / Twitter40 posts
  • YouTube2 videos
  • News2 articles

AI synopsis

What people are saying

The social discussions display a strong consensus on the crucial role of IgA antibodies in defending against SARS-CoV-2, with comments highlighting the limitations of current vaccination approaches that primarily induce IgG responses. For instance, references to IgA’s role in mucosal immunity and the mention of prolonged viral shedding in IgA deficiency suggest a widespread recognition of the article's implications, driven by a tone of scientific curiosity and concern for public health.

AgreementModerate agreement

Most discussions align with the article's emphasis on the importance of IgA in SARS-CoV-2 immune response and potential implications for vaccine strategies.

InterestHigh interest

Participants show high interest, referencing scientific concepts like mucosal immunity and immune deficiencies, and engaging with complex ideas.

EngagementModerate engagement

Posts include personal reactions, references to scientific studies, and calls for understanding, indicating moderate to deep engagement.

ImpactModerate impact

The discussions potentially influence perspectives on immunity and vaccine development, highlighting the significance of IgA in infection control.

Abstract in brief

  • IgA antibodies, produced by B lymphocytes, play a crucial role in defending against various pathogens, including SARS-CoV-2, by protecting epithelial barriers and reducing immune overreaction.
  • During SARS-CoV-2 infection, early immune responses are primarily driven by IgA antibodies, which help in virus neutralization; a deficiency in IgA could lead to more severe COVID-19, vaccine failure, and prolonged viral shedding.
  • Most people with Selective IgA Deficiency are asymptomatic, but the condition may influence COVID-19 severity and immune response, highlighting the need for further research on the impact of IgA absence on SARS-CoV-2 infection.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Ondine Sherwood
@selkieO · X

@ahandvanish The impact of secretary IgA is worth exploring. Wondering if low secretary IgA in the GI tract might be common in #LongCovid https://t.co/iyc5b80o40

Jul 24, 2021 · 11 likes · 4 shares · 1,119 followers View post →
Disruptive Inv
@cards_kid · X

@drgauravchandra @NoUse4aName781 @BischofKirsten @enzolytics Dr Chandra, you have inspired many common folks to read ultra boring topics to understand and appreciate your science and discoveries. This stole 60 mins of my life: https://t.co/mXhczZIh5m Your Science Works! U are trying to Checkmate Virus while others think boosters. https://t.co/NBK9AZqQKx

Oct 7, 2022 · 7 likes · 7 shares · 415 followers View post →
BlisBlis
@BlisBlis2 · X

@marseille_jeff https://t.co/u0gVFyVHMT Ils en parlent justement dans ce cours article .

Jul 24, 2022 · 5 likes · 3 shares · 515 followers View post →
Bocquet Annelise
@AnneliseBocquet · X

@CleoKapp @PinsolleT Les anticorps (AC) sont à double tranchant... par exemple IgA = protection des muqueuses mais impliqués aussi dans la néphropathie. https://t.co/YdTtlm4WCD https://t.co/P4uUYiDBrY. https://t.co/ISc6Z1H5Os

Apr 5, 2022 · 4 likes · 30,213 followers View post →
Chile Piensa Oficial
@chpiensa · X

@AnaLisa_Testa Si. Revisar este conversatorio científico: https://t.co/X8Q1ziKlD8 Revisar referencias de sobre el punto: https://t.co/NrCdwE36eo https://t.co/vXQGhY6CxX https://t.co/BP6YIVxscC https://t.co/7yaED5hc3I https://t.co/pW9dAQI6RO https://t.co/SHgsli8elD

Jun 15, 2022 · 4 likes · 2 shares · 739 followers View post →
Alice Han
@dralicehan · X

@ENirenberg But how long does it take? Is it fast enough to deal with a short incubation period? I got the impression from this article that it could be up to 2 weeks to contain an infection which is too long. https://t.co/s55KADScsT

Jul 27, 2022 · 3 likes · 2,949 followers View post →

All mentions

Ana Calber
@amcalber · X

RT @JosPint34111327: @G_Commish @ejustin46 @Nk9992Nk @supertodd1 @amcalber @dgurdasani1 @VirusesImmunity @EricTopol “modulates excessive im…

Jun 6, 2023 · 1 share · 2,269 followers View post →
José Pinto ✝️ Cristão Novo
@2dedostesta5 · X

@G_Commish @ejustin46 @Nk9992Nk @supertodd1 @amcalber @dgurdasani1 @VirusesImmunity @EricTopol “modulates excessive immune responses” https://t.co/GDJbid2HfD

Jun 5, 2023 · 1 like · 1 share · 21 followers View post →
Pissed off Citizen
@Johnjohntrades · X

RT @cards_kid: @drgauravchandra @NoUse4aName781 @BischofKirsten @enzolytics Dr Chandra, you have inspired many common folks to read ultra b…

Apr 30, 2023 · 7 shares · 1,937 followers View post →
william
@william82804651 · X

RT @cards_kid: @drgauravchandra @NoUse4aName781 @BischofKirsten @enzolytics Dr Chandra, you have inspired many common folks to read ultra b…

Apr 29, 2023 · 7 shares · 961 followers View post →
D
@dwoodru11 · X

RT @cards_kid: @drgauravchandra @NoUse4aName781 @BischofKirsten @enzolytics Dr Chandra, you have inspired many common folks to read ultra b…

Apr 29, 2023 · 7 shares · 1,470 followers View post →
Noisy Nanny.
@NannyNoisy · X

Frontiers | IgA Antibodies and IgA Deficiency in SARS-CoV-2 Infection https://t.co/YnAyeoooRC

Mar 26, 2023 · 391 followers View post →
william
@william82804651 · X

RT @cards_kid: @drgauravchandra @NoUse4aName781 @BischofKirsten @enzolytics Dr Chandra, you have inspired many common folks to read ultra b…

Nov 6, 2022 · 7 shares · 961 followers View post →
D
@dwoodru11 · X

RT @cards_kid: @drgauravchandra @NoUse4aName781 @BischofKirsten @enzolytics Dr Chandra, you have inspired many common folks to read ultra b…

Nov 6, 2022 · 7 shares · 1,470 followers View post →
william
@william82804651 · X

RT @cards_kid: @drgauravchandra @NoUse4aName781 @BischofKirsten @enzolytics Dr Chandra, you have inspired many common folks to read ultra b…

Oct 8, 2022 · 7 shares · 961 followers View post →
Eric Stewert
@Eric_Stewert__ · X

RT @cards_kid: #ENZC family - a must read to understand Dr C's science. https://t.co/mXhczZre3m This confirms what Dr has been telling u…

Oct 8, 2022 · 1 share · 341 followers View post →
Eric Stewert
@Eric_Stewert__ · X

RT @cards_kid: @drgauravchandra @NoUse4aName781 @BischofKirsten @enzolytics Dr Chandra, you have inspired many common folks to read ultra b…

Oct 8, 2022 · 7 shares · 341 followers View post →
Disruptive Inv
@cards_kid · X

#ENZC family - a must read to understand Dr C's science. https://t.co/mXhczZre3m This confirms what Dr has been telling us for over an year. Others think of booster, he is predicting covid/hiv risk, prevention & cure using "mucosal immunity" that vaccines ignore. Go #ENZC! https://t.co/cUgIWMRTg8

Oct 7, 2022 · 1 like · 1 share · 415 followers View post →
Disruptive Inv
@cards_kid · X

@drgauravchandra @NoUse4aName781 @BischofKirsten @enzolytics Dr Chandra, you have inspired many common folks to read ultra boring topics to understand and appreciate your science and discoveries. This stole 60 mins of my life: https://t.co/mXhczZIh5m Your Science Works! U are trying to Checkmate Virus while others think boosters. https://t.co/NBK9AZqQKx

Oct 7, 2022 · 7 likes · 7 shares · 415 followers View post →
B2A au royaume de la dérive en marche
@BMi_99999 · X

RT @BlisBlis2: @marseille_jeff https://t.co/u0gVFyVHMT Ils en parlent justement dans ce cours article .

Jul 28, 2022 · 3 shares · 1,139 followers View post →
Alice Han
@dralicehan · X

@ENirenberg But how long does it take? Is it fast enough to deal with a short incubation period? I got the impression from this article that it could be up to 2 weeks to contain an infection which is too long. https://t.co/s55KADScsT

Jul 27, 2022 · 3 likes · 2,949 followers View post →
Bibpanda
@Bibpanda · X

RT @BlisBlis2: @marseille_jeff https://t.co/u0gVFyVHMT Ils en parlent justement dans ce cours article .

Jul 24, 2022 · 3 shares · 573 followers View post →
R Lhr
@RemLHr · X

RT @BlisBlis2: @marseille_jeff https://t.co/u0gVFyVHMT Ils en parlent justement dans ce cours article .

Jul 24, 2022 · 3 shares · 570 followers View post →
BlisBlis
@BlisBlis2 · X

@marseille_jeff https://t.co/u0gVFyVHMT Ils en parlent justement dans ce cours article .

Jul 24, 2022 · 5 likes · 3 shares · 515 followers View post →
What?
@podz4 · X

@DroletRenee Semble y avoir impact sur sévérité du moins. Et efficacité relative du vaccin. 2 articles https://t.co/8ma0ti6Ktm https://t.co/LDL4U11G7w

Jun 29, 2022 · 1 like · 1,320 followers View post →
Harold Coronado
@harold_coronado · X

RT @chpiensa: @AnaLisa_Testa Si. Revisar este conversatorio científico: https://t.co/X8Q1ziKlD8 Revisar referencias de sobre el punto: htt…

Jun 15, 2022 · 2 shares · 64 followers View post →
sandry
@sandruca4 · X

RT @chpiensa: @AnaLisa_Testa Si. Revisar este conversatorio científico: https://t.co/X8Q1ziKlD8 Revisar referencias de sobre el punto: htt…

Jun 15, 2022 · 2 shares · 2,008 followers View post →
Chile Piensa Oficial
@chpiensa · X

@AnaLisa_Testa Si. Revisar este conversatorio científico: https://t.co/X8Q1ziKlD8 Revisar referencias de sobre el punto: https://t.co/NrCdwE36eo https://t.co/vXQGhY6CxX https://t.co/BP6YIVxscC https://t.co/7yaED5hc3I https://t.co/pW9dAQI6RO https://t.co/SHgsli8elD

Jun 15, 2022 · 4 likes · 2 shares · 739 followers View post →
Bocquet Annelise
@AnneliseBocquet · X

@CleoKapp @PinsolleT Les anticorps (AC) sont à double tranchant... par exemple IgA = protection des muqueuses mais impliqués aussi dans la néphropathie. https://t.co/YdTtlm4WCD https://t.co/P4uUYiDBrY. https://t.co/ISc6Z1H5Os

Apr 5, 2022 · 4 likes · 30,213 followers View post →
TaNaisha NOT MILD Lee Garrett
@TaNaishaJ · X

"[Lack of neutralizing. anti-SARS-Cov-2 IgA & secretory IgA antibodies represents possible cause of prolonged viral shedding in patients w/Selective IgA Deficiency & w/Primary Antibody Deficiencies showing increased length of SARS-CoV-2 positivity.]" https://t.co/K658l6PqlC

Feb 28, 2022 · 2,605 followers View post →
Ingomar Gutmann
@ingomar_gutmann · X

@florian_krammer @firefoxx66 @nextstrain Immunodeficiencies & CoViD persistent infection in PID: https://t.co/Y3kOGGXDhi https://t.co/xQHQTH0Sy9 in host viral evolution https://t.co/JT4cLgf7PM https://t.co/wh3EvUuOwj https://t.co/Xcm8Q02ajI prolonged shedding in IgA deficiency https://t.co/reX5auhPvO 2/2

Nov 27, 2021 · 1 like · 6,016 followers View post →
εº㈉ºз
@ncp_tukky · X

IgA Antibodies and IgA Deficiency in SARS-CoV-2 Infection SARS-CoV-2感染症におけるIgA抗体とIgA欠損症 https://t.co/wLl6jXmMXQ

Nov 22, 2021 · 131 followers View post →
The Science
@MNMike99 · X

@ProfEmilyOster Is it too much for the “experts” espousing vax IgG and IgM to re-read what they missed about IgA? TOUGH TO ELICIT sIGA IN INTRAMUSCULAR INJECTIONS…{But I love ya’ll too}…. Ps, if I hear ‘breakthrough case’ again, I might kill myself. https://t.co/vnUBvbUG7V

Sep 27, 2021 · 252 followers View post →
Shelley Shenton
@shelleyshenton · X

@CIPONational https://t.co/oIHBtFiP8k

Sep 2, 2021 · 1,904 followers View post →
Martyn Holman
@holmanma · X

@theJeremyVine @custardsmaster @ajchristofi @Ady48683409 As to the original point, given there is no sterilising immunity (unlike natural immunity) it is of course likely that you@transmit the virus as a vaccinated or unvaccinated individual https://t.co/sLOlENG2Da

Aug 29, 2021 · 496 followers View post →
anonymous_md
@MdBlockchain · X

https://t.co/y5SwTcNIOg

Aug 12, 2021 · 1 like · 24 followers View post →
Alvaro Rial
@RialAlvaro · X

RT @selkieO: @ahandvanish The impact of secretary IgA is worth exploring. Wondering if low secretary IgA in the GI tract might be common in…

Jul 25, 2021 · 4 shares · 660 followers View post →
Priceless2020 #FBLC
@Priceless20201 · X

RT @selkieO: @ahandvanish The impact of secretary IgA is worth exploring. Wondering if low secretary IgA in the GI tract might be common in…

Jul 24, 2021 · 4 shares · 1,203 followers View post →
Esther Rodriguez
@Draroro · X

RT @selkieO: @ahandvanish The impact of secretary IgA is worth exploring. Wondering if low secretary IgA in the GI tract might be common in…

Jul 24, 2021 · 4 shares · 524 followers View post →
Hannah Davis
@ahandvanish · X

RT @selkieO: @ahandvanish The impact of secretary IgA is worth exploring. Wondering if low secretary IgA in the GI tract might be common in…

Jul 24, 2021 · 4 shares · 56,137 followers View post →
Ondine Sherwood
@selkieO · X

@ahandvanish The impact of secretary IgA is worth exploring. Wondering if low secretary IgA in the GI tract might be common in #LongCovid https://t.co/iyc5b80o40

Jul 24, 2021 · 11 likes · 4 shares · 1,119 followers View post →
R137K
@R137K · X

@SebaVermeulen @zegerdebyser "anderzijds is er wel een zekere verworven immuniteit tegen influenza; " Dat is tov sars-cov-2 niet anders --> https://t.co/uhbxFHXQHX Bovendien kan deze immuniteit steriel zijn, in tegenstelling tot die welke via vaccinatie wordt verworven --> https://t.co/y96mXMpu2F IGA

Jul 5, 2021 · 1 like · 529 followers View post →
Xiwen
@Xiwen · X

@HolgerHamburgo @FoooBarBazz @DrPuerner @ulrikeguerot https://t.co/wUSLqeCyvS https://t.co/myzJh25YwX https://t.co/plPNetYR3p https://t.co/n2WvgkDwJo

Jun 27, 2021 · 232 followers View post →
Cristian
@MDveter · X

RT @arztdiego: IgA Antibodies and IgA Deficiency in SARS-CoV-2 Infection https://t.co/uUJwZhlbYc

Apr 25, 2021 · 1 share · 606 followers View post →
Dr Diego Mpia Elenge
@arztdiego · X

IgA Antibodies and IgA Deficiency in SARS-CoV-2 Infection https://t.co/uUJwZhlbYc

Apr 25, 2021 · 1 like · 1 share · 1,441 followers View post →
Frontiers - Infectious Disease
@FrontInfectDis · X

IgA Antibodies and IgA Deficiency in SARS-CoV-2 Infection https://t.co/ZZXZUGaGYa #cellinfect

Apr 22, 2021 · 1 like · 3,839 followers View post →