PubHawk
April 2021 PMID 33921522

Histamine Intolerance Originates in the Gut.

Wolfgang J Schnedl, Dietmar Enko

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Mentions

85
Peak: 12 in Apr 2021
across 6 sources since Apr 2021

Extended reach

270,655
potential audience

Total likes

1,198

Video views

42,389

Mentions per month

Apr 2021 – Dec 2025

Where it's discussed

  • TikTok33 posts
  • X / Twitter28 posts
  • Instagram17 posts
  • YouTube3 videos
  • Facebook3 posts
  • News1 articles

AI synopsis

What people are saying

The group largely agrees that histamine intolerance originates in the gut, with expressions like 'this is life' and statements about the importance of avoiding gut dysbiosis, indicating broad support. Interest is indicated by remarks about the slowly building science and potential health implications, while engagement is shown through mentions of dietary modifications and gut health strategies that suggest active consideration of the topic's practical impact.

AgreementModerate agreement

Most discussions accept the idea that histamine intolerance originates in the gut, as evidenced by repeated affirmations of this concept in the posts.

InterestHigh interest

Participants show high curiosity about the topic, with multiple posts indicating that they find the science or implications of gut-related histamine issues intriguing.

EngagementModerate engagement

Posts include references to dietary impacts, gut health strategies, and ongoing research, suggesting a moderate depth of discussion.

ImpactModerate impact

The discussions are starting to influence awareness, emphasizing the role of gut health in histamine issues, which could guide future health approaches.

Abstract in brief

  • Histamine intolerance (HIT) is mainly caused by a deficiency of the enzyme diamine oxidase (DAO) in the gut, leading to poor breakdown of histamine from food, which can cause various gastrointestinal and extraintestinal symptoms.
  • Diagnosing HIT is difficult because traditional tests, like measuring DAO levels in serum, do not always reflect gut activity, so diagnosis mainly relies on a detailed patient history and standardized questionnaires, often supported by dietary changes or DAO supplements.
  • The article emphasizes that HIT is a gastrointestinal disorder originating in the gut, and considering histamine levels should be part of diagnosing unexplained health issues and GI complaints with no clear cause.
Read the full abstract

Top posts

Most liked on X and Bluesky
Kate Scarlata, MPH, RDN
@KateScarlata_RD · X

I find this topic interesting, and the science is slowly building, could histamine overload (from diet, mast cell release) lead to GI + extra intestinal symptoms? Histamine Intolerance Originates in the Gut https://t.co/vE0jABKlWY

Feb 2, 2022 · 31 likes · 7 shares · 12,431 followers View post →
J P Fanton
@HealthyFellow · X

#Histamine Intolerance Begins in the #Gut Attn: ⁦@_atanas_⁩ ⁦@_INPST⁩ ⁦@ScienceCommuni2⁩ ⁦@PharmacistPaleo⁩ ⁦@DrPedre⁩ ⁦@bioMioSoftware⁩ ⁦@DrPalmquist⁩ ⁦@deNutrients⁩ ⁦@BrianLenzkes⁩ ⁦@club_gut⁩ https://t.co/DPnmjw4E9i

Apr 12, 2021 · 27 likes · 8 shares · 25,979 followers View post →
George Ferman
@Helios_Movement · X

4) Avoid things that contribute to gut dysbiosis. https://t.co/Q5ofEHQNgj https://t.co/AzTLH1DHWj https://t.co/ABJxznbFHL https://t.co/cNRJDvtpEX Once again, this is life, you can’t perfectly avoid everything that can contribute to gut dysbiosis but we know for example that

May 1, 2025 · 22 likes · 3 shares · 85,124 followers View post →
KOJI@プライマルコーチ
@kojija · X

【ヒスタミン不耐と消化器障害】 ヒスタミン不耐性（HIT）は、胃腸（GI）酵素のジアミンオキシダーゼ（DAO）の欠乏が原因 食品成分のヒスタミンが消化管内で適切に分解および/または吸収されていない https://t.co/05gRDyLfcE https://t.co/Tg8EZm99GU

Apr 12, 2021 · 9 likes · 1 share · 2,315 followers View post →
Dr. Suzana Mantovani
@Tweet_Nutrition · X

#Histamine Intolerance Originates in the #Gut https://t.co/3USpGpiv1V

Nov 21, 2022 · 5 likes · 4,559 followers View post →
UltimApe
@ultimape · X

@Grimhood @Mithreu @ck_eternity_ "In this review, we discuss currently increasing evidence that [Histamine Intolerance] is primarily a gastrointestinal disorder and that it originates in the gut." [MAR 2021]

May 18, 2023 · 3 likes · 6,774 followers View post →

All mentions

Maya
@Maya126873 · X

RT @Helios_Movement: 4) Avoid things that contribute to gut dysbiosis. https://t.co/Q5ofEHQNgj https://t.co/AzTLH1DHWj https://t.co/AB…

May 1, 2025 · 3 shares · 5,539 followers View post →
Renee Poche
@poche_renee17 · X

RT @Helios_Movement: 4) Avoid things that contribute to gut dysbiosis. https://t.co/Q5ofEHQNgj https://t.co/AzTLH1DHWj https://t.co/AB…

May 1, 2025 · 3 shares · 1,802 followers View post →
George Ferman
@Helios_Movement · X

4) Avoid things that contribute to gut dysbiosis. https://t.co/Q5ofEHQNgj https://t.co/AzTLH1DHWj https://t.co/ABJxznbFHL https://t.co/cNRJDvtpEX Once again, this is life, you can’t perfectly avoid everything that can contribute to gut dysbiosis but we know for example that

May 1, 2025 · 22 likes · 3 shares · 85,124 followers View post →
Churlish Insubordinate
@sparklecopy · X

Histamine Intolerance Originates in the Gut https://t.co/nMuFXUCBKA

Oct 30, 2023 · 96 followers View post →
Carol Evans, MD
@Carol_Evans_MD · X

Histamine Intolerance Originates in the Gut - PMC https://t.co/7hVmh0NHtW

Aug 7, 2023 · 4,035 followers View post →
UltimApe
@ultimape · X

@Grimhood @Mithreu @ck_eternity_ "In this review, we discuss currently increasing evidence that [Histamine Intolerance] is primarily a gastrointestinal disorder and that it originates in the gut." [MAR 2021]

May 18, 2023 · 3 likes · 6,774 followers View post →
Dr. Suzana Mantovani
@Tweet_Nutrition · X

#Histamine Intolerance Originates in the #Gut https://t.co/3USpGpiv1V

Nov 21, 2022 · 5 likes · 4,559 followers View post →
Debbie @ Genetic Lifehacks
@GeneticLifehack · X

Histamine Intolerance Originates in the Gut https://t.co/IQYhtRXuc0

Apr 27, 2022 · 1 like · 1,595 followers View post →
Maren Rinker CNP
@DrRinker · X

RT @KateScarlata_RD: I find this topic interesting, and the science is slowly building, could histamine overload (from diet, mast cell rele…

Feb 22, 2022 · 7 shares · 30 followers View post →
Mellodi Zintkala
@MZintkala · X

RT @KateScarlata_RD: I find this topic interesting, and the science is slowly building, could histamine overload (from diet, mast cell rele…

Feb 13, 2022 · 7 shares · 5,604 followers View post →
Mallory, MS, RD
@malllllll_13 · X

RT @KateScarlata_RD: I find this topic interesting, and the science is slowly building, could histamine overload (from diet, mast cell rele…

Feb 5, 2022 · 7 shares · 245 followers View post →
Lacey Dunn, MS, RD, LD, CPT
@laceyadunn · X

RT @KateScarlata_RD: I find this topic interesting, and the science is slowly building, could histamine overload (from diet, mast cell rele…

Feb 2, 2022 · 7 shares · 13,703 followers View post →
Samar Harris MD
@SamarHarris2 · X

RT @KateScarlata_RD: I find this topic interesting, and the science is slowly building, could histamine overload (from diet, mast cell rele…

Feb 2, 2022 · 7 shares · 263 followers View post →
Kate Scarlata, MPH, RDN
@KateScarlata_RD · X

I find this topic interesting, and the science is slowly building, could histamine overload (from diet, mast cell release) lead to GI + extra intestinal symptoms? Histamine Intolerance Originates in the Gut https://t.co/vE0jABKlWY

Feb 2, 2022 · 31 likes · 7 shares · 12,431 followers View post →
Debbie @ Genetic Lifehacks
@GeneticLifehack · X

Histamine Intolerance Originates in the Gut https://t.co/IntDT9pKVE

Nov 8, 2021 · 1 like · 1,595 followers View post →
Rノ助
@HEELJPN · X

RT @kojija: 【ヒスタミン不耐と消化器障害】 ヒスタミン不耐性（HIT）は、胃腸（GI）酵素のジアミンオキシダーゼ（DAO）の欠乏が原因 食品成分のヒスタミンが消化管内で適切に分解および/または吸収されていない https://t.co/05gRDyLfcE

Jul 31, 2021 · 1 share · 262 followers View post →
Keto Diet Zone
@KetoDietZone · X

Histamine Intolerance Originates in the Gut https://t.co/Xc7CAl8xbx

Apr 22, 2021 · 13,069 followers View post →
Keto Diet Zone
@KetoDietZone · X

Histamine Intolerance Originates in the Gut https://t.co/Xc7CAl8xbx

Apr 19, 2021 · 1 like · 13,069 followers View post →
Diana
@PharmphoodTM · X

RT @HealthyFellow: #Histamine Intolerance Begins in the #Gut Attn: ⁦@_atanas_⁩ ⁦@_INPST⁩ ⁦@ScienceCommuni2⁩ ⁦@PharmacistPaleo⁩ ⁦@DrPedre⁩ ⁦…

Apr 12, 2021 · 8 shares · 556 followers View post →
KOJI@プライマルコーチ
@kojija · X

【ヒスタミン不耐と消化器障害】 ヒスタミン不耐性（HIT）は、胃腸（GI）酵素のジアミンオキシダーゼ（DAO）の欠乏が原因 食品成分のヒスタミンが消化管内で適切に分解および/または吸収されていない https://t.co/05gRDyLfcE https://t.co/Tg8EZm99GU

Apr 12, 2021 · 9 likes · 1 share · 2,315 followers View post →
Dr. Suzana Mantovani
@Tweet_Nutrition · X

RT @HealthyFellow: #Histamine Intolerance Begins in the #Gut Attn: ⁦@_atanas_⁩ ⁦@_INPST⁩ ⁦@ScienceCommuni2⁩ ⁦@PharmacistPaleo⁩ ⁦@DrPedre⁩ ⁦…

Apr 12, 2021 · 8 shares · 4,559 followers View post →
Super Super!
@Ariesdirection · X

RT @HealthyFellow: #Histamine Intolerance Begins in the #Gut Attn: ⁦@_atanas_⁩ ⁦@_INPST⁩ ⁦@ScienceCommuni2⁩ ⁦@PharmacistPaleo⁩ ⁦@DrPedre⁩ ⁦…

Apr 12, 2021 · 8 shares · 428 followers View post →
DrRPalmquist
@DrPalmquist · X

RT @HealthyFellow: #Histamine Intolerance Begins in the #Gut Attn: ⁦@_atanas_⁩ ⁦@_INPST⁩ ⁦@ScienceCommuni2⁩ ⁦@PharmacistPaleo⁩ ⁦@DrPedre⁩ ⁦…

Apr 12, 2021 · 8 shares · 3,157 followers View post →
Maurício Lima
@dj_surfista · X

A intolerância à #histamina origina-se no intestino. #HistamineIntolerance https://t.co/mPJ0SQUC4S

Apr 12, 2021 · 1 like · 755 followers View post →
The GUT CLUB
@club_gut · X

RT @HealthyFellow: #Histamine Intolerance Begins in the #Gut Attn: ⁦@_atanas_⁩ ⁦@_INPST⁩ ⁦@ScienceCommuni2⁩ ⁦@PharmacistPaleo⁩ ⁦@DrPedre⁩ ⁦…

Apr 12, 2021 · 8 shares · 2,362 followers View post →
Dr. د. عبدالواحد الزهراني
@ralzahrani2020 · X

RT @HealthyFellow: #Histamine Intolerance Begins in the #Gut Attn: ⁦@_atanas_⁩ ⁦@_INPST⁩ ⁦@ScienceCommuni2⁩ ⁦@PharmacistPaleo⁩ ⁦@DrPedre⁩ ⁦…

Apr 12, 2021 · 8 shares · 4,899 followers View post →
Travis Statham
@Travis_Statham · X

RT @HealthyFellow: #Histamine Intolerance Begins in the #Gut Attn: ⁦@_atanas_⁩ ⁦@_INPST⁩ ⁦@ScienceCommuni2⁩ ⁦@PharmacistPaleo⁩ ⁦@DrPedre⁩ ⁦…

Apr 12, 2021 · 8 shares · 12,688 followers View post →
J P Fanton
@HealthyFellow · X

#Histamine Intolerance Begins in the #Gut Attn: ⁦@_atanas_⁩ ⁦@_INPST⁩ ⁦@ScienceCommuni2⁩ ⁦@PharmacistPaleo⁩ ⁦@DrPedre⁩ ⁦@bioMioSoftware⁩ ⁦@DrPalmquist⁩ ⁦@deNutrients⁩ ⁦@BrianLenzkes⁩ ⁦@club_gut⁩ https://t.co/DPnmjw4E9i

Apr 12, 2021 · 27 likes · 8 shares · 25,979 followers View post →
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2021, doi:10.3390/nu13041262. Schnedl, Wolfgang J et al. “Evaluation of symptoms and symptom combinations in histamine intolerance ...

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Natural Remedies for Chronic Urticaria: Effective Ways to Treat ...
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“Histamine Intolerance Originates in the Gut.” Nutrients vol. 13,4 1262. 12 Apr. 2021, doi:10.3390/nu13041262. Urticaria Crónica: ¿Puede lo que ...

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Muitos não sabem mais o que comer, pois o alimento que sempre ...
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... 10.3390/nu13041262). Há pessoas que apresentam polimorfismos genéticos nessas enzimas, o que dificulta processar a histamina, tornando ainda ...

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13,4 1262. 12 Apr. 2021, doi:10.3390/nu13041262. more. View all 37 comments. October 12 · dottojorge's profile picture · dottojorge. •. Follow.

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Jorge Dotto - El problema que tiene Colorado, EEUU por la ...
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... Originates in the Gut.” Nutrients vol. 13,4 1262. 12 Apr. 2021, doi:10.3390/nu13041262. Miriam Galvan and 4 others ·

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