Elife May 2021 PMID 33942717

Mesoscale phase separation of chromatin in the nucleus.

Gaurav Bajpai, Daria Amiad Pavlov, Dana Lorber, Talila Volk, Samuel Safran

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Mentions

38
Peak: 14 in Oct 2020
across 4 sources since Oct 2020

Extended reach

212,043
potential audience

Total likes

46

Video views

1,134

Mentions per month

Oct 2020 – Nov 2022

Where it's discussed

  • X / Twitter23 posts
  • News10 articles
  • Blogs3 articles
  • YouTube2 videos

AI synopsis

What people are saying

The posts demonstrate strong support and keen interest in the article, with phrases like 'excited to share' and 'great job' indicating enthusiasm, while mentions of the publication being 'online' or 'accepted' reflect active engagement. The tone and context show that the research is considered important for understanding physical mechanisms of chromatin behavior, likely influencing ongoing biological and biophysical studies.

AgreementModerate agreement

Most individuals recognize the importance of the research, expressing enthusiasm and approval for the study and its implications.

InterestHigh interest

Discussions show high interest, with many posts highlighting excitement for the findings and their relevance to chromatin organization.

EngagementModerate engagement

Posts reflect a moderate level of engagement, including sharing publication details, expressing personal praise, and referencing related predictions or models.

ImpactModerate impact

The discourse suggests the findings are seen as impactful within biophysics and cell biology communities, emphasizing advances in understanding nuclear organization.

Abstract in brief

  • The study uses imaging of larvae to observe how chromatin (DNA and associated proteins) separates into different phases inside the nucleus, either near the nuclear envelope or throughout the nucleus, influenced by nuclear volume and interactions with the lamina.
  • A simple polymer model shows that the distribution of chromatin depends on the balance between its self-attraction and binding to the lamina, which explains the different organizational states observed in the nucleus.
  • The findings reveal that these chromatin phase behaviors are governed by fundamental physical mechanisms, and the model's predictions match well with actual biological observations in organisms.

Top posts

Most liked on X and Bluesky
Gaurav Bajpai
@GauravB84033224 · X

Excited to share our work "Mesoscale phase separation of chromatin in the nucleus", accepted by the eLife journal https://t.co/Nv1WSRkX8O

May 5, 2021 · 11 likes · 1 share · 125 followers View post →
Phase Transition Papers
@Pha_Tran_Papers · X

Mesoscale phase separation of chromatin in the nucleus https://t.co/bhVEcYkW9t

May 28, 2021 · 10 likes · 3,587 followers View post →
Gaurav Bajpai
@GauravB84033224 · X

Our eLife paper is online. Mesoscale phase separation of chromatin in the nucleus https://t.co/Nv1WSRkX8O

May 23, 2021 · 7 likes · 2 shares · 125 followers View post →
Daria Amiad Pavlov
@AmiadDaria · X

Further details and predications of the model were recently published by @eLife. Great job @GauravB84033224 and we enjoyed working with you on that. https://t.co/9UEJp7gDiX

Jun 3, 2021 · 4 likes · 1 share · 187 followers View post →
bioRxiv
@biorxivpreprint · X

Mesoscale phase separation of chromatin in the nucleus https://t.co/pTvkX3LJvX #bioRxiv

Oct 24, 2020 · 3 likes · 2 shares · 137,017 followers View post →
Jumana AlHaj Abed
@JumanaAHA · X

Gaurav Bajpai @GauravB84033224 Mesoscale phase separation of chromatin in the nucleus Postdoc in Safran's lab, Weizmann Institute

Jul 30, 2021 · 3 likes · 1,110 followers View post →

All mentions

PELK
@LyfeOfPELK · X

$SPY https://t.co/79HBTKuKkD

Sep 8, 2021 · 2,828 followers View post →
Jumana AlHaj Abed
@JumanaAHA · X

Gaurav Bajpai @GauravB84033224 Mesoscale phase separation of chromatin in the nucleus Postdoc in Safran's lab, Weizmann Institute

Jul 30, 2021 · 3 likes · 1,110 followers View post →
Gaurav Bajpai
@GauravB84033224 · X

RT @AmiadDaria: Further details and predications of the model were recently published by @eLife. Great job @GauravB84033224 and we enjoyed…

Jun 3, 2021 · 1 share · 125 followers View post →
Daria Amiad Pavlov
@AmiadDaria · X

Further details and predications of the model were recently published by @eLife. Great job @GauravB84033224 and we enjoyed working with you on that. https://t.co/9UEJp7gDiX

Jun 3, 2021 · 4 likes · 1 share · 187 followers View post →
Phase Transition Papers
@Pha_Tran_Papers · X

Mesoscale phase separation of chromatin in the nucleus https://t.co/bhVEcYkW9t

May 28, 2021 · 10 likes · 3,587 followers View post →
Ranjith Padinhateeri
@ranjithpa · X

RT @GauravB84033224: Our eLife paper is online. Mesoscale phase separation of chromatin in the nucleus https://t.co/Nv1WSRkX8O

May 24, 2021 · 2 shares · 2,138 followers View post →
Kiran K.
@KiranKumari_ · X

RT @GauravB84033224: Our eLife paper is online. Mesoscale phase separation of chromatin in the nucleus https://t.co/Nv1WSRkX8O

May 23, 2021 · 2 shares · 163 followers View post →
Gaurav Bajpai
@GauravB84033224 · X

Our eLife paper is online. Mesoscale phase separation of chromatin in the nucleus https://t.co/Nv1WSRkX8O

May 23, 2021 · 7 likes · 2 shares · 125 followers View post →
Gaurav Bajpai
@GauravB84033224 · X

Excited to share our work "Mesoscale phase separation of chromatin in the nucleus", accepted by the eLife journal https://t.co/Nv1WSRkX8O

May 5, 2021 · 11 likes · 1 share · 125 followers View post →
BlackPhysicists
@BlackPhysicists · X

Mesoscale phase separation of chromatin in the nucleus https://t.co/LrDi0YsF27 #biophysics https://t.co/NAjjepaPTk

Oct 29, 2020 · 25,134 followers View post →
kwitschas
@kwitschas · X

RT @GauravB84033224: Mesoscale phase separation of chromatin in the nucleus https://t.co/HsnYgPnX4w

Oct 25, 2020 · 2 shares · 1,793 followers View post →
Dan Deviri
@DDeviri · X

RT @GauravB84033224: Mesoscale phase separation of chromatin in the nucleus https://t.co/HsnYgPnX4w

Oct 25, 2020 · 2 shares · 246 followers View post →
Gaurav Bajpai
@GauravB84033224 · X

RT @biorxivpreprint: Mesoscale phase separation of chromatin in the nucleus https://t.co/pTvkX3LJvX #bioRxiv

Oct 24, 2020 · 2 shares · 125 followers View post →
Gaurav Bajpai
@GauravB84033224 · X

Mesoscale phase separation of chromatin in the nucleus https://t.co/HsnYgPnX4w

Oct 24, 2020 · 3 likes · 2 shares · 125 followers View post →
Jennifer Madrigal
@jenchemfolife · X

RT @biorxiv_biophys: Mesoscale phase separation of chromatin in the nucleus https://t.co/GuDSUmYA6y #biorxiv_biophys

Oct 24, 2020 · 1 share · 441 followers View post →
Phase Transition Papers
@Pha_Tran_Papers · X

Mesoscale phase separation of chromatin in the nucleus https://t.co/8j2E7wSJft

Oct 24, 2020 · 3,587 followers View post →
Hugo Rubalcava
@HugoRubalcava · X

RT @biorxivpreprint: Mesoscale phase separation of chromatin in the nucleus https://t.co/pTvkX3LJvX #bioRxiv

Oct 24, 2020 · 2 shares · 262 followers View post →
bioRxiv Biophysics
@biorxiv_biophys · X

Mesoscale phase separation of chromatin in the nucleus https://t.co/GuDSUmYA6y #biorxiv_biophys

Oct 24, 2020 · 1 share · 5,374 followers View post →
bioRxiv
@biorxivpreprint · X

Mesoscale phase separation of chromatin in the nucleus https://t.co/pTvkX3LJvX #bioRxiv

Oct 24, 2020 · 3 likes · 2 shares · 137,017 followers View post →
LoveLovePS
@LoveLovePS1 · X

RT @BlackPhysicists: Mesoscale phase separation of chromatin in the nucleus. (arXiv:2010.07655v1 [https://t.co/li4CT731AA]) https://t.co/c6…

Oct 16, 2020 · 1 share · 26 followers View post →
BlackPhysicists
@BlackPhysicists · X

Mesoscale phase separation of chromatin in the nucleus. (arXiv:2010.07655v1 [https://t.co/li4CT731AA]) https://t.co/c6zJRx2ltE #biophysics

Oct 16, 2020 · 1 share · 25,134 followers View post →
arXiv physics.bio-ph
@ArxivBiophys · X

Mesoscale phase separation of chromatin in the nucleus. (arXiv:2010.07655v1 [physics.bio-ph]) https://t.co/Hu61EgTv1F

Oct 15, 2020 · 59 followers View post →
arXiv physics
@_arXiv_physics · X

[2010.07655] Gaurav Bajpai, Daria Amiad-Pavlov, Dana Lorber et al.: Mesoscale phase separation of chromatin in the nucleus https://t.co/ML1JA87DAZ https://t.co/o5yHxJjWgt #physics_bio_ph

Oct 15, 2020 · 1,149 followers View post →