May 2021 PMID 33953396

Response of the microbiome-gut-brain axis in Drosophila to amino acid deficit.

Boram Kim, Makoto I Kanai, Yangkyun Oh, Minsoo Kyung, Eun-Kyoung Kim, In-Hwan Jang, Ji-Hoon Lee, Sang-Gyu Kim, Greg S B Suh, Won-Jae Lee

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Mentions

Peak: 30 in May 2021

across 6 sources since May 2021

Extended reach

337,053

potential audience

Total likes

201

Video views

13,844

Mentions per month

May 2021 – Sep 2023

Where it's discussed

X / Twitter31 posts
News11 articles
Facebook3 posts
Reddit3 posts
Blogs3 articles
YouTube2 videos

AI synopsis

What people are saying

The discussions highlight intrigue about how gut cells can detect specific amino acid deficits, as seen in remarks like 'very creative research' and 'interesting that enterocytes can sense even a deficit of single amino acids.' The tone varies from curiosity to recognition of the study’s significance, showing moderate engagement focused on understanding mechanisms and potential biological implications.

AgreementModerate agreement

Most discussions positively acknowledge the novelty and importance of the research, with some expressing surprise at how gut cells can detect individual amino acids and the microbiome's role in supplementing nutrients.

InterestHigh interest

Posts show strong curiosity, especially around the mechanisms of amino acid sensing and the microbiome’s influence, reflected in phrases like 'very creative research' and 'interesting that enterocytes can sense.'

EngagementModerate engagement

Several discussions briefly note the significance of the findings, with some comments referencing broader biological concepts, indicating moderate but not deeply detailed engagement.

ImpactModerate impact

The tone suggests users see the study as a meaningful contribution to understanding gut-brain interactions, though few explicitly mention practical or broad impacts, resulting in a moderate rating.

Abstract in brief

The study shows that in Drosophila, a microbiome-gut-brain axis detects dietary amino acid deficits and triggers a specific hunger response for essential amino acids (EAAs), with the neuropeptide CNMa playing a key role in signaling this need.
When flies are deprived of EAAs, CNMa is highly expressed in gut cells, and blocking its signaling prevents the hunger response, while microbiomes that produce EAAs reduce the flies' appetite for these amino acids.
The findings suggest that both gut cells and microbiota coordinate to monitor amino acid levels and communicate deficiencies to the brain, influencing feeding behavior to maintain nutritional balance.]

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Ryusuke Niwa

@TsukubaNiwaLab · X

Our online journal club by RH. Response of the microbiome–gut–brain axis in Drosophila to amino acid deficit. From Drs. Greg S. B. Suh & Won-Jae Lee's labs. #nature https://t.co/RAA7vIoMjm

Jun 8, 2021 · 1,007 followers View post →

Nicholas Osborne

@nosborne36 · X

Response of the microbiome–gut–brain axis in Drosophila to amino acid deficit https://t.co/GmWInfO9Vb

May 31, 2021 · 1,121 followers View post →

Annika Reads

@papersofnote · X

Not only do enterocytes detect essential amino acid (EAA) deficits and communicate to the brain with CNMa to influence feeding decisions, but gut bacteria can help supplement EAAs when protein intake is low. https://t.co/P8rrcJVCka

May 28, 2021 · 1,063 followers View post →

Paper-worm

@Yoolab_JC · X

JC by HC. Response of the microbiome–gut–brain axis in Drosophila to amino acid deficit by Won-Jae Lee. https://t.co/2TUaIvnmlU Very creative research. It's interesting that enterocytes can sense even a deficit of single amino acids.

May 15, 2021 · 72 followers View post →

Agingdoc

@agingdoc1 · X

Response of the microbiome–gut–brain axis in Drosophila to amino acid deficit https://t.co/FZEWv0UpCZ @nature

May 11, 2021 · 2 likes · 41,918 followers View post →

Adam J Rose

@DrAJRose · X

Response of the #microbiome–#gut–#brain axis in Drosophila to an amino acid deficient #diet https://t.co/RJcb1DN1Ib

May 11, 2021 · 3 likes · 809 followers View post →

humanest

@humanest5 · X

RT @Pon_yurublog: #論文紹介食欲のコントロールが腸内細菌によってされているというNatureのハエを用いた脳腸相関の研究

May 10, 2021 · 1 share · 315 followers View post →

Pon｜食と健康

@PonNutr · X

#論文紹介食欲のコントロールが腸内細菌によってされているというNatureのハエを用いた脳腸相関の研究

May 10, 2021 · 6 likes · 1 share · 2,722 followers View post →

GutMicrobiomePapers

@GutPapers · X

Response of the microbiome-gut-brain axis in Drosophila to amino acid deficit https://t.co/7P21AhDAxJ

May 9, 2021 · 519 followers View post →

AB Johnson

@Hijo_de_Juan · X

RT @jfcryan: Response of the microbiome–gut–brain axis in Drosophila to amino acid deficit | Nature https://t.co/SsAbbhoMbc

May 9, 2021 · 5 shares · 154 followers View post →

Jacob Guenther

@JacobAGuenther · X

RT @MicrobiomDigest: Response of the microbiome–gut–brain axis in Drosophila to amino acid deficit * 'gut enterocytes sense the levels of d…

May 8, 2021 · 2 shares · 782 followers View post →

Elisabeth Bik

@MicrobiomDigest · X

May 8, 2021 · 16 likes · 2 shares · 143,424 followers View post →

Ah-Ram Kim

@ahramkim1128 · X

Response of the microbiome–gut–brain axis in Drosophila to amino acid deficit https://t.co/fC6ru5uj8s

May 7, 2021 · 2 likes · 283 followers View post →

Paul McCullough

@ThePostsynaptic · X

Response of the microbiome–gut–brain axis in Drosophila to amino acid deficit https://t.co/1vT7l9YOh0 https://t.co/NHfXyZuRnT

May 7, 2021 · 2,589 followers View post →

Bill Sullivan

@wjsullivan · X

Response of the microbiome–gut–brain axis in Drosophila to amino acid deficit https://t.co/EmFwiMmkp1

May 7, 2021 · 4,856 followers View post →

jose Miguel Gonzalez Clemente

@josemiguelgclem · X

Response of the microbiome–gut–brain axis in Drosophila to amino acid deficit | Nature https://t.co/PGoWWaSk2C

May 7, 2021 · 100 followers View post →

Symbiosis papers

@Symbiosispapers · X

Response of the microbiome-gut-brain axis in Drosophila to amino acid deficit https://t.co/8l4HTdaYSH

May 6, 2021 · 1,109 followers View post →

UCC Innovation

@uccinnovation · X

RT @jfcryan: Response of the microbiome–gut–brain axis in Drosophila to amino acid deficit | Nature https://t.co/SsAbbhoMbc

May 6, 2021 · 5 shares · 1,124 followers View post →

UCC Medicine & Health

@UCCMedHealth · X

RT @jfcryan: Response of the microbiome–gut–brain axis in Drosophila to amino acid deficit | Nature https://t.co/SsAbbhoMbc

May 6, 2021 · 5 shares · 4,500 followers View post →

Julia Dallman

@DallmanLab · X

RT @jfcryan: Response of the microbiome–gut–brain axis in Drosophila to amino acid deficit | Nature https://t.co/SsAbbhoMbc

May 6, 2021 · 5 shares · 298 followers View post →

APC Microbiome Ireland

@Pharmabiotic · X

RT @jfcryan: Response of the microbiome–gut–brain axis in Drosophila to amino acid deficit | Nature https://t.co/SsAbbhoMbc

May 6, 2021 · 5 shares · 11,237 followers View post →

藝人である“Ju•NIOR”【

@aruberutou · X

Response of the microbiome–gut–brain axis in Drosophila to amino acid deficit https://t.co/1GRwBaQSkw https://t.co/2qkqDDUQ08 | #research #manuscripts @nature

May 6, 2021 · 202 followers View post →

Benjamin Valderrama

@bpvalderrama · X

Response of the microbiome–gut–brain axis in Drosophila to amino acid deficit https://t.co/FckFyVjN9m

May 5, 2021 · 310 followers View post →

John F. Cryan

@jfcryan · X

Response of the microbiome–gut–brain axis in Drosophila to amino acid deficit | Nature https://t.co/SsAbbhoMbc

May 5, 2021 · 22 likes · 5 shares · 22,440 followers View post →

Théodore Grenier

@TheodoreGrenier · X

RT @kipnislab: Response of the microbiome–gut–brain axis in Drosophila to amino acid deficit || https://t.co/r8LLeNzMrC

May 5, 2021 · 4 shares · 186 followers View post →

Aaron Reinke

@Reinke_Science · X

RT @kipnislab: Response of the microbiome–gut–brain axis in Drosophila to amino acid deficit || https://t.co/r8LLeNzMrC

May 5, 2021 · 4 shares · 778 followers View post →

Igor Iatsenko

@IatsenkoIgor · X

RT @kipnislab: Response of the microbiome–gut–brain axis in Drosophila to amino acid deficit || https://t.co/r8LLeNzMrC

May 5, 2021 · 4 shares · 297 followers View post →

Public Journal Club

@publicjournalc · X

RT @kipnislab: Response of the microbiome–gut–brain axis in Drosophila to amino acid deficit || https://t.co/r8LLeNzMrC

May 5, 2021 · 4 shares · 1,813 followers View post →

Francis Villatoro

@emulenews · X

May 5, 2021 · 3 likes · 45,156 followers View post →

FrezzaLab

@FrezzaLab · X

Response of the microbiome–gut–brain axis in Drosophila to amino acid deficit | Nature https://t.co/SFMBScMmru

May 5, 2021 · 1 like · 26,967 followers View post →

Kipnis Lab

@kipnislab · X

Response of the microbiome–gut–brain axis in Drosophila to amino acid deficit || https://t.co/r8LLeNzMrC

May 5, 2021 · 25 likes · 4 shares · 4,947 followers View post →

Response of the microbiome-gut-brain axis in Drosophila to amino acid deficit.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

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