EMBO Mol Med July 2021 PMID 34041853

NAD homeostasis in human health and disease.

Rubén Zapata-Pérez, Ronald J A Wanders, Clara D M van Karnebeek, Riekelt H Houtkooper

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Peak: 49 in Aug 2021

across 4 sources since May 2021

Extended reach

153,526

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2,195

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May 2021 – Jul 2025

Where it's discussed

X / Twitter72 posts
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AI synopsis

What people are saying

Numerous discussions highlight the importance of maintaining NAD levels, with users sharing their excitement about its potential benefits. For instance, one user expressed curiosity about why nicotinamide riboside could be more beneficial than nicotinamide itself, showcasing a desire for deeper understanding. The phrase 'therapeutic potential' is frequently used, along with links to various related studies, reflecting a serious consideration of the topic and its relevance in health discussions.

AgreementModerate agreement

The majority of discussions indicate a supportive stance toward the research findings, though there are some questions raised.

InterestHigh interest

The posts reflect a high level of curiosity and relevance regarding NAD+ and its implications for health and disease.

EngagementModerate engagement

While many posts reference the article, deeper discussions around specific components and personal insights are somewhat limited.

ImpactHigh impact

Many users perceive the research as having significant implications for future therapies and health improvements.

Abstract in brief

NAD (nicotinamide adenine dinucleotide) is crucial for human health, as its depletion can lead to various diseases due to issues in its biosynthesis or increased consumption.
Deficiencies in NAD can result in both rare inherited conditions, like congenital malformations, and more common age-related diseases, highlighting the importance of maintaining NAD levels.
The text also explores current research on potential therapies aimed at replenishing NAD to improve health and treat different diseases, using various NAD-enhancing agents.

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All mentions

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Exploring NAD: Health Benefits and Supplementation Strategies

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EsperanzaBenRam

@EsperanzaBenRam · X

@MonteCarola https://t.co/W7pzmbDzHs

Jul 3, 2025 · 1 like · 1,175 followers View post →

Knut Hamsun

@Broken8iron · X

@PeterJAnderson_ @eh_den Definitely... nicotinic acid https://t.co/k8WD2jxhdz

Jan 18, 2023 · 437 followers View post →

Brett

@brettdusek · X

Jan 16, 2023 · 7 likes · 2,815 followers View post →

ENDALA klinika zdraví

@endalaclinic · X

NAD+ homeostasis in human health and disease - PMC https://t.co/4FfxT3JozC

May 12, 2022 · 1 like · 253 followers View post →

ENDALA klinika zdraví

@endalaclinic · X

NAD+ homeostasis in human health and disease | EMBO Molecular Medicine https://t.co/7kHokLt97t

Apr 4, 2022 · 1 like · 253 followers View post →

ENDALA klinika zdraví

@endalaclinic · X

NAD+ homeostasis in human health and disease - PMC https://t.co/4FfxT3JozC

Mar 27, 2022 · 1 like · 253 followers View post →

Hiro@Neurobadminton

@12hiroki07 · X

NAD+ homeostasis in human health and disease | EMBO Molecular Medicine https://t.co/d5JLpfo7yW

Mar 5, 2022 · 43 followers View post →

umptemp

@Umptemping · X

RT @babataiki326: #2022年論文紹介63 の補足2 細胞内のNAD代謝を理解するのに打ってつけの総説！(EMBO Mol Med) 画像は、Figure.2より引用。 https://t.co/N7wgcqeCJm https://t.co/Y10DRi…

Mar 5, 2022 · 4 shares · 40 followers View post →

@mo_mo_taro_33 · X

Mar 5, 2022 · 4 shares · 35 followers View post →

SNZK

@shinopp · X

Mar 5, 2022 · 4 shares · 721 followers View post →

Taiki Baba

@babataiki326 · X

Mar 5, 2022 · 20 likes · 4 shares · 2,707 followers View post →

ENDALA klinika zdraví

@endalaclinic · X

NAD+ homeostasis in human health and disease - PMC https://t.co/QI02ni95uR

Feb 11, 2022 · 253 followers View post →

Riekelt Houtkooper

@rhhoutkooper · X

RT @rhhoutkooper: Interested in NAD+? Check out our new review, led by @RZapataPerez, on the topic in @EmboMolMed. We discuss how NAD chang…

Jan 25, 2022 · 15 shares · 1,662 followers View post →

ACB

@ACBPhysio · X

@CharlesMBrenner @WeightInnovate @JohnOblong My bad, was just rereading this article https://t.co/eapQ4cYYrB . Thanks for replying! I do question now why NR would be more benificial to just Nicotinamide? Or maybe science is figuring this out?

Jan 3, 2022 · 221 followers View post →

Dr. Luis Calderón Murga

@drlecalderon · X

NAD+ homeostasis in human health and disease | EMBO Molecular Medicine https://t.co/NFzel9fxOa

Nov 28, 2021 · 109 followers View post →

WeThePeeple

@WeThePeeple9 · X

NAD+ homeostasis in human health and disease https://t.co/rLdFzWbIC5 #NIATONIN https://t.co/vS1gDGzbdx

Sep 14, 2021 · 1 like · 939 followers View post →

ENDALA klinika zdraví

@endalaclinic · X

NAD+ homeostasis in human health and disease | EMBO Molecular Medicine https://t.co/7kHokLt97t

Sep 6, 2021 · 253 followers View post →

PT,DPT,MOM

@maranatha202709 · X

NAD + homeostasis in human health and disease https://t.co/W5szVstJVM

Sep 6, 2021 · 229 followers View post →

Véronique WoayeHune

@verowoayehune · X

NAD+ homeostasis in human health and disease | EMBO Molecular Medicine https://t.co/fHkgttI6ql

Sep 5, 2021 · 2 followers View post →

ENDALA klinika zdraví

@endalaclinic · X

NAD+ homeostasis in human health and disease https://t.co/QI02ni95uR

Sep 4, 2021 · 253 followers View post →

ENDALA klinika zdraví

@endalaclinic · X

NAD+ homeostasis in human health and disease https://t.co/QI02ni95uR

Aug 31, 2021 · 253 followers View post →

Pia Angeles Barrios H

@PiaAngelesBarri · X

RT @GastonFRodrigu1: Homeostasis NAD+ en salud y enfermedad humana | EMBO Molecular Medicine https://t.co/4IQVoUpkUu

Aug 23, 2021 · 1 share · 476 followers View post →

ENDALA klinika zdraví

@endalaclinic · X

NAD+ homeostasis in human health and disease https://t.co/4FfxT3JozC

Aug 17, 2021 · 253 followers View post →

Sailesh Palikhe

@saileshpalikhe · X

https://t.co/rTLiLsAn0y

Aug 9, 2021 · 145 followers View post →

David Haldorsen MA, ISSA-EPT-SCC-SN

@YourCoachDavid · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 67,403 followers View post →

Muhammad

@AlienBrainA · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 146 followers View post →

Tran Rick

@TranRick2 · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 48 followers View post →

Kanon Broussard

@kanonb05 · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 84 followers View post →

Alexander  Boman

@AlexanderBoman · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 482 followers View post →

LatinJedi

@LatinJedi · X

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Aug 8, 2021 · 226 shares · 533 followers View post →

The Imagined

@Imagiknowledge · X

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Aug 8, 2021 · 226 shares · 99 followers View post →

i ∞ Δ Mary Grace

@MARYGRACEMGMG · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 95 followers View post →

Doug Devine

@devinedoug · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 385 followers View post →

Dr Rashid Zaman FRCPsych

@DrRZaman · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 2,344 followers View post →

Dr. Ayush Yadav

@ProxyAyush · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 307 followers View post →

Sohail Mohammed

@sohailmohammed0 · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 189 followers View post →

B_XY

@B_XY_16 · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 78 followers View post →

Greg Van Horn

@gvh41 · X

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Aug 8, 2021 · 226 shares · 2,967 followers View post →

Marylou E. Miner

@marylouminer · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 239 followers View post →

SR Sajjad

@_srsajjad · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 261 followers View post →

Matt

@mwl312 · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 199 followers View post →

Brian Dean

@bdean_ · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 556 followers View post →

AlfredoPietracatella

@alfredopietraca · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 244 followers View post →

Brian Keane

@br_keane_ian · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 255 followers View post →

Alex

@lex_akeem · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 152 followers View post →

Hazrat Hussain

@HazratH77530444 · X

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Aug 8, 2021 · 226 shares · 5 followers View post →

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@BraveNewtWorld · X

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Varun Jain

@globalnomad86 · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 19 followers View post →

Tim Foxon

@tkfoxon · X

Am I misunderstanding this? https://t.co/M8u6nYLmPE

Aug 8, 2021 · 103 followers View post →

Brandon

@rideburton87 · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 75 followers View post →

Nicola Marino

@nikmarino9 · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 8,775 followers View post →

Probability

@probabilitysci · X

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Aug 8, 2021 · 226 shares · 338 followers View post →

Kashif Ansari

@ansarikashif7 · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 739 followers View post →

nickolas jensen

@NickolasJensen · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 220 followers View post →

Dimon Lers

@Dimon_Lers · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 845 followers View post →

Vikuna Lion

@vikuna29 · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 624 followers View post →

Oyague

@brunos_mind · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 302 followers View post →

Liz Gallese

@LizGalleseM · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 1,663 followers View post →

Josiah Phillip

@JosiahPhillipX · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 29 followers View post →

Giorgos Vachtanidis

@gvachtan · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 2,128 followers View post →

Matthias Boehm

@matthiasboehm7 · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 1,326 followers View post →

Rich Hurt

@richhurt · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 389 followers View post →

Michael Pfluger

@mikepfluger · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 186 followers View post →

João

@joaopeniche1 · X

RT @davidasinclair: So excited about my 8-part podcast series. Will dedicate an entire show separating fact from fiction about the use of N…

Aug 8, 2021 · 226 shares · 423 followers View post →

Dr L Boominathan PhD

@DrLBoominathan · X

NAD+ homeostasis in human health and disease | EMBO Molecular Medicine https://t.co/tF2B9Tf7Tr https://t.co/PglG6Vs5oB

Aug 8, 2021 · 1 like · 878 followers View post →

Dr L Boominathan PhD

@DrLBoominathan · X

NAD+ homeostasis in human health and disease | EMBO Molecular Medicine https://t.co/1tgfVyl0pE https://t.co/gIFWNBAr9X

Aug 8, 2021 · 878 followers View post →

ENDALA klinika zdraví

@endalaclinic · X

NAD+ homeostasis in human health and disease https://t.co/4FfxT3JozC

Aug 6, 2021 · 253 followers View post →

EMBO Mol. Medicine

@EmboMolMed · X

RT @AutonomicAus: NAD+ homeostasis in human health and disease, review by researchers at @amsterdamumc & @radboudumc, in @EmboMolMed: @EMBO…

Aug 5, 2021 · 1 share · 9,403 followers View post →

Autonomic Aus

@AutonomicAus · X

Aug 5, 2021 · 4 likes · 1 share · 349 followers View post →

Nivedita seshadri

@Niveditaseshad2 · X

RT @josephwgordon: NAD+ homeostasis in human health and disease | EMBO Molecular Medicine https://t.co/ENe7Gg3Bz8

Jul 8, 2021 · 1 share · 232 followers View post →

Kelly A. Hogan Ph.D.

@Loose_Lab_Rat · X

NAD + homeostasis in human health and disease https://t.co/FRzkGmEdcZ

May 28, 2021 · 2,241 followers View post →

EMBO Mol. Medicine

@EmboMolMed · X

May 27, 2021 · 5 likes · 9,403 followers View post →

NAD homeostasis in human health and disease.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Exploring NAD Supplements: Enhancing Health and Longevity

Exploring NAD: Health Benefits and Supplementation Strategies