Signal Transduct Target Ther May 2021 PMID 34054126

Small molecules in targeted cancer therapy: advances, challenges, and future perspectives.

Lei Zhong, Yueshan Li, Liang Xiong, Wenjing Wang, Ming Wu, Ting Yuan, Wei Yang, Chenyu Tian, Zhuang Miao, Tianqi Wang, Shengyong Yang

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Mentions

11
Peak: 1 in Nov 2021
across 3 sources since Nov 2021

Extended reach

3,048
potential audience

Total likes

3

Video views

113

Mentions per month

Nov 2021 – Mar 2025

Where it's discussed

  • X / Twitter4 posts
  • YouTube4 videos
  • News3 articles

AI synopsis

What people are saying

The overall discussions reflect a positive perception of small molecules in cancer treatment, emphasizing their advantages like targeted action, safety, and regulatory approval, with phrases like 'high potency and low toxicity' indicating recognition of their importance, but without extensive critical analysis or detailed exploration of ongoing challenges.

AgreementModerate agreement

The posts generally agree with the idea that small molecules are beneficial and have gained approval due to their efficacy and safety, reflecting a positive stance.

InterestModerate interest

Posts express a moderate interest, highlighting developments and approvals, but lack deeper curiosity or critique.

EngagementModerate engagement

The discussions briefly touch on clinical implications and approval processes, indicating some engagement with the topic but not in-depth analysis.

ImpactModerate impact

The posts acknowledge the significance of small molecules in cancer therapy, suggesting they are impactful within the medical and research community.

Abstract in brief

  • Since the approval of imatinib in 2001, there has been significant progress in developing small-molecule targeted drugs for cancer treatment, with 89 approved by major regulatory bodies by 2020.
  • Despite these advancements, targeted anticancer drugs still face major challenges like low response rates and drug resistance, limiting their effectiveness.
  • The review categorizes these drugs based on their targets, discussing approved options, ongoing clinical trials, challenges, and future research directions to improve treatment outcomes.]

Top posts

Most liked on X and Bluesky
Little Coco
@LittleCoco83812 · X

@iluminatibot Small molecules in targeted cancer therapy: advances, challenges, and future perspectives Due to the advantages in efficacy and safety compared with traditional chemotherapy drugs, targeted therapeutic drugs have become mainstream cancer treatments. Since the first tyrosine

Mar 6, 2025 · 1,022 followers View post →
Little Coco
@LittleCoco83812 · X

@iluminatibot Small molecules in targeted cancer therapy: advances, challenges, and future perspectives Due to the advantages in efficacy and safety compared with traditional chemotherapy drugs, targeted therapeutic drugs have become mainstream cancer treatments. Since the first tyrosine

Jan 29, 2025 · 1,022 followers View post →
filippo masini
@filimasini · X

Small molecules in targeted cancer therapy: advances, challenges, and future perspectives https://t.co/sodnQ5YWQO

Nov 11, 2021 · 770 followers View post →
Shatha Algheribe
@algheribe · X

Small molecules as cancer therapy:) Small molecules that target cancerous tumor cells but spare normal cells, additionally, having high potency and low toxicity; hence, get the FDA approval in the past 20 years. #fda#KAIMARC https://t.co/FfhcrV2IAi https://t.co/OpTz5iHF27

Jan 4, 2022 · 123 followers View post →

All mentions

Little Coco
@LittleCoco83812 · X

@iluminatibot Small molecules in targeted cancer therapy: advances, challenges, and future perspectives Due to the advantages in efficacy and safety compared with traditional chemotherapy drugs, targeted therapeutic drugs have become mainstream cancer treatments. Since the first tyrosine

Mar 6, 2025 · 1,022 followers View post →
Little Coco
@LittleCoco83812 · X

@iluminatibot Small molecules in targeted cancer therapy: advances, challenges, and future perspectives Due to the advantages in efficacy and safety compared with traditional chemotherapy drugs, targeted therapeutic drugs have become mainstream cancer treatments. Since the first tyrosine

Jan 29, 2025 · 1,022 followers View post →
Shatha Algheribe
@algheribe · X

Small molecules as cancer therapy:) Small molecules that target cancerous tumor cells but spare normal cells, additionally, having high potency and low toxicity; hence, get the FDA approval in the past 20 years. #fda#KAIMARC https://t.co/FfhcrV2IAi https://t.co/OpTz5iHF27

Jan 4, 2022 · 123 followers View post →
filippo masini
@filimasini · X

Small molecules in targeted cancer therapy: advances, challenges, and future perspectives https://t.co/sodnQ5YWQO

Nov 11, 2021 · 770 followers View post →