June 2022 PMID 34159872

Minoxidil: a comprehensive review.

A K Gupta, M Talukder, M Venkataraman, M A Bamimore

Mentions

33
Peak: 4 in Nov 2023
across 7 sources since Jun 2021

Extended reach

95,480
potential audience

Total likes

2,002

Video views

86,033

Mentions per month

Jun 2021 – Nov 2025

Where it's discussed

  • Reddit10 posts
  • News10 articles
  • X / Twitter6 posts
  • YouTube2 videos
  • Facebook2 posts
  • TikTok2 posts
  • Instagram1 posts

AI synopsis

What people are saying

Discussions reveal strong agreement with the benefits of minoxidil, exemplified by comments on its various formulations like foam and solution, and mentions of its mechanism as a vasodilator and anti-inflammatory agent. The tone and language focus on practical applications and potential effectiveness, indicating active interest and moderate engagement with the review's contents.

AgreementModerate agreement

Most discussions show support or accept the findings of the comprehensive review on minoxidil, indicated by mentions of positive effects and approval status.

InterestHigh interest

The posts demonstrate a high level of curiosity about formulations, dosages, and applications, reflecting genuine interest in the topic.

EngagementModerate engagement

Participants reference mechanisms of action, formulation details, and express opinions, suggesting moderate but meaningful engagement.

ImpactModerate impact

The discussions could influence opinions or behaviors regarding hair loss treatments, as users highlight the effectiveness and approval status of minoxidil.

Abstract in brief

  • Minoxidil is FDA-approved for treating androgenetic alopecia (AGA) in men and women, and it works through multiple mechanisms including vasodilation, anti-inflammatory effects, promoting hair growth pathways, and possibly acting as an antiandrogen.
  • Approximately 14% of topical minoxidil is absorbed through the skin, where it is metabolized into its active form, minoxidil sulfate, by follicular sulfotransferase, with response rates varying based on enzyme activity.
  • The treatment generally shows peak hair growth around the first year, with similar efficacy between different formulations (foam and solution), and lower doses may still be effective, especially for female pattern hair loss; sublingual delivery might also be a safe option.

Top posts

Most liked on X and Bluesky
Jovan Lalošević
@docajoca · X

@Mornar_parobrod @AgencyTEABOOKS https://t.co/aazkQcq1AR A evo i jedan svez rad, da ne bude da me je mrzelo ;)

Nov 26, 2023 · 2 likes · 4,899 followers View post →
ビビリ@AGA治療歴5年
@bibiriaga · X

塗りミノよりミノタブのほうが発毛効果は高そうですね。 ただ副作用を考えると、塗りミノから使うのがいいのかなと思いますね。 レビュー論文「ミノキシジル5mg/日を6ヶ月間使用した結果、男性AGAにおいて外用薬(塗りミノ)2%および5%よりも有意に高い効果を示した」 https://t.co/al2KamV7ix https://t.co/sFaKrSl1zL

Apr 1, 2023 · 2 likes · 429 followers View post →
天狗先生
@tengu_mcc · X

ミノキシジルの外用は1.4%の吸収率と言われてます。5%ミノキシジル1mlに含まれるミノキシジルは0.05gでさらに1.4%しか吸収されないとなると、安全容量と言われてる0.625mg-1.25mgより少ないので安全かと思います、、! https://t.co/kJPzDVVbeQ https://t.co/bFm7q4L5cn https://t.co/EfqksuwqmC

Jun 8, 2023 · 1 like · 271 followers View post →
`
@aldbciaoan · X

@Frances06437371 @ilb4ttista https://t.co/8ulRgARQqI

Nov 22, 2025 · 2,184 followers View post →
Dataemia
@Dataemia · X

(Minoxidil: a comprehensive review) https://t.co/xfGSfQ1oDF

Jun 24, 2021 · 959 followers View post →
Wnt publications
@WntPublications · X

Minoxidil: a comprehensive review: Topical minoxidil (5% foam, 5% solution, 2% solution) is FDA-approved for androgenetic alopecia (AGA) in men and women.Mechanism of action: Minoxidil acts through multiple pathways (vasodilator, anti-inflammatory agent,… https://t.co/9Vjt2HaYFj

Jun 24, 2021 · 456 followers View post →

All mentions

`
@aldbciaoan · X

@Frances06437371 @ilb4ttista https://t.co/8ulRgARQqI

Nov 22, 2025 · 2,184 followers View post →
Jovan Lalošević
@docajoca · X

@Mornar_parobrod @AgencyTEABOOKS https://t.co/aazkQcq1AR A evo i jedan svez rad, da ne bude da me je mrzelo ;)

Nov 26, 2023 · 2 likes · 4,899 followers View post →
天狗先生
@tengu_mcc · X

ミノキシジルの外用は1.4%の吸収率と言われてます。5%ミノキシジル1mlに含まれるミノキシジルは0.05gでさらに1.4%しか吸収されないとなると、安全容量と言われてる0.625mg-1.25mgより少ないので安全かと思います、、! https://t.co/kJPzDVVbeQ https://t.co/bFm7q4L5cn https://t.co/EfqksuwqmC

Jun 8, 2023 · 1 like · 271 followers View post →
ビビリ@AGA治療歴5年
@bibiriaga · X

塗りミノよりミノタブのほうが発毛効果は高そうですね。 ただ副作用を考えると、塗りミノから使うのがいいのかなと思いますね。 レビュー論文「ミノキシジル5mg/日を6ヶ月間使用した結果、男性AGAにおいて外用薬(塗りミノ)2%および5%よりも有意に高い効果を示した」 https://t.co/al2KamV7ix https://t.co/sFaKrSl1zL

Apr 1, 2023 · 2 likes · 429 followers View post →
Wnt publications
@WntPublications · X

Minoxidil: a comprehensive review: Topical minoxidil (5% foam, 5% solution, 2% solution) is FDA-approved for androgenetic alopecia (AGA) in men and women.Mechanism of action: Minoxidil acts through multiple pathways (vasodilator, anti-inflammatory agent,… https://t.co/9Vjt2HaYFj

Jun 24, 2021 · 456 followers View post →
Dataemia
@Dataemia · X

(Minoxidil: a comprehensive review) https://t.co/xfGSfQ1oDF

Jun 24, 2021 · 959 followers View post →
Alopecia Areata: An Updated Review For 2023: Cathryn Sibbald ...
News

J Dermatolog Treat. 105. Almutairi N, Nour TM, Hussain NH. Janus kinase inhibitors 2022;33(4):1896-1906. ​doi:​10.1080/09546634.2021.1945527 for the ...

Dec 26, 2025 View →
JEADV Clinical Practice - 2022 - Dominguez Santas - The State of ...
News

https://doi.org/10.1080/09546634.2021.1945527. AGA and a framework to help the dermatologist navigate 5. Gupta AK, Venkataraman M, Talukder M, Bamimore MA ...

Dec 26, 2025 View →
Best Hair Loss Treatments for Men for 2026: Costs, Benefits, and More
News

... 10.1080/09546634.2021.1945527?journalCode=ijdt20; Hair loss: Overview. (n.d.). https://www.aad.org/public/diseases/hair-loss/causes/fall-out ...

Nov 24, 2025 View →
Extended-Release Minoxidil Shows Promise in AGA | Dermatology ...
News

doi:10.1080/09546634.2021.1945527; Shapiro J, Senna M, Muller-Ramos P, Lo Sicco K. Comparative efficacy of an investigational oral minoxidil ...

Oct 6, 2025 View →
Ilmu pengetahuan > mitos turun-temurun. #minoxidil #hairgrowth ...
TikTok

TikTok video from Izdihaar Grow (@izdihaargrow): “Ilmu pengetahuan > mitos turun-temurun. #minoxidil #hairgrowth #alopecia #penumbuhrambut ...

Aug 22, 2025 View →
Pupuk buat tanaman? Sama kayak minoxidil buat rambut ...
TikTok

TikTok video from Izdihaar Grow (@izdihaargrow): “Pupuk buat tanaman? Sama kayak minoxidil buat rambut. #minoxidil #hairgrowth #alopecia ...

Aug 20, 2025 View →
Oral vs Topical Minoxidil: Which Should You Choose?
News

https://doi.org/10.1080/09546634.2021.1945527; Gupta AK, Talukder M, Shemar A, Piraccini BM, Tosti A. Low-Dose Oral Minoxidil for Alopecia: A ...

Jun 28, 2025 View →
Ketakutan Terhadap Minoxidil Oral Terlalu Berlebihan : r/tressless
Reddit

... 10.1080/09546634.2021.1945527 mempunyai kadar penyerapan 1.4% dalam datanya, menyokong tanggapan penyerapan 1.5%. Lebih ramai orang ada ...

Jun 25, 2025 View →
الخوف من المينوكسيديل الفموي مبالغ فيه : r/tressless
Reddit

... 10.1080/09546634.2021.1945527 ، معدل الامتصاص فيها 1.4% في بياناتها، وده بيدعم فكرة امتصاص 1.5%. ناس أكتر عندها مشاكل مع تفاعلات الحساسية لـ ...

Jun 25, 2025 View →
The Fear of Oral Minoxidil is Overblown : r/tressless
Reddit

Whereas, topical, with the most recent study being published in 2022: https://www.tandfonline.com/doi/full/10.1080/09546634.2021.1945527 has ...

Jun 25, 2025 View →
Hvor kan en gymnasieelev tilgå forsknings artikler med begrænset ...
Reddit

... Dermatological Treatment, vol. 33, no. 4, 2022, pp. 1896–906, https://doi.org/10.1080/09546634.2021.1945527. magnificentcabbage. • 8 mdr. siden.

Mar 30, 2025 View →
Low-Dose Oral Minoxidil Initiation for Patients With Hair Loss An ...
News

doi:10.1080/09546634.2021.1945527. 7. US Food and Drug Administration. Loniten. (minoxidil). Pfizer Inc. January 2015. Accessed. October 15 ...

Nov 20, 2024 View →
PCOS and hair loss: Causes, treatments, and more
News

Minoxidil: A comprehensive review. https://www.tandfonline.com/doi/full/10.1080/09546634.2021.1945527; Hoover E, et al. (2023). Physiology ...

Oct 9, 2024 View →
CG and Minoxidil Combination Therapy Shows Promise for AA ...
News

doi:10.1080/09546634.2021.1945527; Nestor MS, Ablon G, Gade A, et al. Treatment options for androgenetic alopecia: Efficacy, side effects ...

Sep 10, 2024 View →
Alopecias ‍ ‍ ‍ y tratamiento con Minoxidil vía oral!! Excelente ...
Instagram

18 likes, 4 comments - dra.ramirezacunia on May 2, 2024: "Alopecias ‍ ‍ ‍ y tratamiento con Minoxidil vía oral!! Excelente presentación!

May 2, 2024 View →
Uma abordagem holística para o re-crescimento : r/HairlossResearch
Reddit

... 10.1080/09546634.2021.1945527). Como se tornar um hiperrespondedor ao minoxidil? Você precisa de alta atividade de sulfotransferase e do ...

Nov 13, 2023 View →
全面复苏的整体方法: r/HairlossResearch
Reddit

... 10.1080/09546634.2021.1945527). 如何成为米诺地尔超级反应者? 你需要高磺基转移酶活性,并且你需要活性代谢物(米诺地尔硫酸盐)在你的目标结构 ...

Nov 13, 2023 View →
A holistic approach to re-growth : r/HairlossResearch
Reddit

... 10.1080/09546634.2021.1945527). How to become a minoxidil hyper-responder? You need high sulfotransferase activity and you need the bioactive ...

Nov 13, 2023 View →
14 months on the juice : r/Minoxbeards
Reddit

doi:10.1080/09546634.2021.1945527 13. Suchonwanit P, Thammarucha S, Leerunyakul K. Minoxidil and its use in hair disorders: a review. Drug ...

Aug 31, 2023 View →
Does Rogaine Work? On Thin Hair, Hair Loss, and More
News

Minoxidil: A comprehensive review. https://www.tandfonline.com/doi/abs/10.1080/09546634.2021.1945527?journalCode=ijdt20; Hair loss: Signs and ...

Jun 28, 2023 View →
Does Rogaine Work?
News

Minoxidil: A comprehensive review [Abstract]. https://www.tandfonline.com/doi/abs/10.1080/09546634.2021.1945527?journalCode=ijdt20; Hosking ...

May 18, 2023 View →
!FULL STUDY! Safety of low-dose oral minoxidil for hair loss : r ...
Reddit

... hub.se/https://doi.org/10.1080/09546634.2021.1945527 · https://sci-hub.se/https://doi.org/10.1016/j.jaad.2020.05.129. [deleted]. • 3y ago.

Sep 27, 2022 View →
Cognitive/systemic side effects of topical minoxidil. : r ...
Reddit

... 10.1080/09546634.2021.1945527?needAccess=true&journalCode=ijdt20. Community Info Section. r/HairlossResearch. Join. Hairloss Research.

Jul 29, 2022 View →
Hỏi Đáp với BSCKI. Pham Tang Tung | Facebook
Facebook

10.1080/09546634.2021.1945527. Epub ahead of print. PMID: 34159872.

Oct 10, 2021 View →
Hỏi Đáp với BSCKI. Pham Tang Tung - Facebook
Facebook

... . J Dermatolog Treat. 2021 Jul 20:1-11. doi: 10.1080/09546634.2021.1945527. Epub ahead of print. PMID: 34159872. All reactions: 1. Like. Comment ...

Sep 15, 2021 View →