The discussions reveal a general agreement on the importance of the genetic research presented, with mentions of Dr. Russo's work, identification of genetic markers like COMT and CYP2C9, and the study’s potential to influence understanding of CHS. The tone varies from supportive to cautiously optimistic, emphasizing the possible biological underpinnings and the ongoing debate within the cannabis community about causes and etiology.
AgreementModerate agreement
Most discussions acknowledge the significance of the research, with many referencing Dr. Ethan Russo's contributions and genetic findings, indicating support for the study's conclusions.
InterestHigh interest
The discourse reflects a high level of curiosity and attention towards the genetic aspects and implications of CHS, demonstrated by mentions of ongoing studies and potential for future research.
EngagementModerate engagement
Participants reference specific details like genetic markers, study authors, and implications, showing some depth of engagement, though not uniformly extensive.
ImpactModerate impact
The findings are viewed as potentially influential, especially given the mention of genetic markers and controversy, though the overall perception of immediate real-world impact is moderate.
Abstract in brief
This study analyzed the largest group of patients with Cannabinoid Hyperemesis Syndrome (CHS), identifying specific genetic mutations linked to the condition, particularly in genes related to neurotransmitters, the endocannabinoid system, and cannabinoid metabolism.
Patients with CHS often experienced symptom improvement after stopping cannabis, but symptoms frequently recurred upon resumption, highlighting the link between ongoing THC exposure and the syndrome.
Despite some reluctance to undergo genetic testing, the research uncovered significant genetic differences in CHS patients, pointing to potential biological factors underlying susceptibility to the syndrome amid increasing cannabis use.]
Eine der größten Umfragen zu #CHS untersuchte genetische Anomalien bei Betroffenen und fand Hinweise auf mögliche genetische Prädispositionen.
https://t.co/SPGFvTFSAV
Jun 6, 2025 · 19 likes · 7,970 followersView post →
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Sanho Tree
@SanhoTree · X
Cannabinoid Hyperemesis Syndrome Survey and Genomic Investigation https://t.co/DS59fNgoBg “Five mutations with plausible etiological roles in the phenomenology of CHS symptoms and signs have been identified with statistical significance from a small dataset.”
Welcome to CannaInsights. This episode explores Cannabinoid Hyperemesis Syndrome (CHS), a rising medical condition linked to long-term cannabis use. Learn about symptoms, diagnosis, treatments, and the importance of…
Dr. Ethan Russo discusses the latest research on Cannabinoid Hyperemesis Syndrome, including symptoms, risk factors, genetic predispositions, and screening possibilities. The study highlights genetic mutations…
Eine der größten Umfragen zu #CHS untersuchte genetische Anomalien bei Betroffenen und fand Hinweise auf mögliche genetische Prädispositionen.
https://t.co/SPGFvTFSAV
Jun 6, 2025 · 19 likes · 7,970 followersView post →
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Matt Elrod
@melrod42 · X
@DACAustralia One can't scream and vomit at the same time.
https://t.co/tlmOZfQquZ
Aug 26, 2023 · 1 like · 120,902 followersView post →
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Matt Elrod
@melrod42 · X
@gahard @CoDoc442 @JustinTrudeau @KevinSabet I'm skeptical of 38%. Yes, maybe CHS goes up with potency but, as I understand it, there's probably a genetic vulnerability. CHS results (for some) from long-term, heavy use, so dose is more relevant than potency. Experienced consumers titrate their dose.
https://t.co/tlmOZfQquZ
"Scromiting" is a seldom used slang term for screaming and vomiting. Screaming is a seldom seen symptom. Both symptoms may or may not be associated with CHS, a rare condition arising in a few vulnerable consumers from long-term, heavy cannabis consumption.
https://t.co/tlmOZfyhgR https://t.co/mxp5tQPpXr
@DrMarcusDay @SteveTransform @EveSimmns @snopes @MetroUK A cannabis OD, or contaminants, can cause vomiting, but that's not the same thing as CHS, which requires heavy consumption over a long period of time.
https://t.co/tlmOZfyhgR
Many CHS sufferers disbelieve THC overexposure etiology and abstinence for remission; alternative hypothesis, exposure to neem; may appear with chronic use of synthetic K2/Spice. Opinions of etiology, 30% - problem ECS, 6% - pesticides, 2% - neem. https://t.co/gWIo9E8wEw
Jun 23, 2022 · 1 like · 2,134 followersView post →
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Matt Elrod
@melrod42 · X
@AngelJustice121 @CoDoc442 Although some who have been diagnosed with CHS have suspected contaminants, several lines of evidence implicate cannabinoids, especially THC. There also seems to be a genetic component. That is, only some long-term, heavy, chronic consumers are at risk.
https://t.co/tlmOZfPSFr
@ToxoftheNorth @ketaminh @EMAJournal Hmmm...Be interesting to see if your future work supports the notion in this paper by Russo et al that CHS is a "manifestation of gene–environment interaction in a rare genetic disease unmasked by a toxic reaction to excessive THC exposure." https://t.co/WFgaBQfmwH
@lucprevost Dr. Ethan Russo has patented a test for markers in CHS patients - hopefully it'll be commercialized soon.
https://t.co/sm335UibMt
Dec 6, 2021 · 1 like · 1 share · 1,928 followersView post →
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#LearnAndTeachOthers
@LearnAndTeachO1 · X
RT @CannabisCourse1: [1/4] Cannabinoid Hyperemesis Syndrome
"In July, a group led by Dr. Ethan Russo released a research study entitled "C…
Nov 24, 2021 · 4 shares · 1,053 followersView post →
นอ
น้ำอ้อยดำต้มกับใบเตยหอมลดไขมันในเลือด
@poongsaleesuk13 · X
RT @CannabisCourse1: [1/4] Cannabinoid Hyperemesis Syndrome
"In July, a group led by Dr. Ethan Russo released a research study entitled "C…
Nov 15, 2021 · 4 shares · 724 followersView post →
HL
Higher Learning LV
@HigherLvtm · X
RT @CannabisCourse1: [1/4] Cannabinoid Hyperemesis Syndrome
"In July, a group led by Dr. Ethan Russo released a research study entitled "C…
Nov 15, 2021 · 4 shares · 1,775 followersView post →
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Andrew Proudfoot
@ProudyMan1 · X
@Peter_Grinspoon @StefanKertesz Not an expert … but Dr Russo is and I found this recent paper a good read on the topic : https://t.co/WFgaBPXdiz
Nov 12, 2021 · 3 likes · 1,116 followersView post →
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Gooey Rabinski
@RobbinsGroupLLC · X
RT @HigherLvtm: Quick Read: Cannabinoid Hyperemesis Syndrome > https://t.co/Gb8jvmPYUe
"In July 2021, researchers led by Dr. Ethan Russo r…
Oct 3, 2021 · 1 share · 12,255 followersView post →
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Higher Learning LV
@HigherLvtm · X
Quick Read: Cannabinoid Hyperemesis Syndrome > https://t.co/Gb8jvmPYUe
"In July 2021, researchers led by Dr. Ethan Russo released a study entitled 'Cannabinoid #Hyperemesis Syndrome Survey and Genomic Investigation' published in the journal #Cannabis and #Cannabinoid Research." https://t.co/nfJwPCNgm4
Oct 2, 2021 · 3 likes · 1 share · 1,775 followersView post →
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#LearnAndTeachOthers
@LearnAndTeachO1 · X
[NEW] The latest in the free Quick Read Series: Cannabinoid Hyperemesis Syndrome > https://t.co/Vl5BNbIz4I
"In July 2021, Dr. Ethan Russo, a neurologist, released a study called Cannabinoid Hyperemesis Syndrome Survey and Genomic Investigation."
#LearnAndTeachOthers™ https://t.co/LB9v7DI6px
@justinleiby @NBCNews Not all of it is bs. For consideration, check out this recent study about Cannabinoid Hyperemesis Syndrome. cc’d @LenMayDNA
https://t.co/o4fzJ9FMvc
Jul 15, 2021 · 1 like · 4,942 followersView post →
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Andrew Proudfoot
@ProudyMan1 · X
@doc_aussie @WCInvestor Some useful recent research and commentary on this topic here from Dr Ethan Russo (was the Neurologist at GW Pharma behind development of sativex):
https://t.co/WFgaBPXdiz
https://t.co/WObDv4HurW
Jul 15, 2021 · 1 like · 1,116 followersView post →
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California NORML
@CaliforniaNORML · X
RT @CannaClinicians: Check out the newly published paper on #CannabinoidHyperemesisSyndrome featuring SCC contributors Dr. Ethan Russo & Ni…
Check out the newly published paper on #CannabinoidHyperemesisSyndrome featuring SCC contributors Dr. Ethan Russo & Nishi Whiteley. They will be discussing their findings during a special edition of journal club on August 20th.
https://t.co/cYmXVtU1J4
#ethanrusso #nishiwhiteley https://t.co/fPBfyVbbP0
Cannabinoid Hyperemesis Syndrome Survey and Genomic Investigation https://t.co/DS59fNgoBg “Five mutations with plausible etiological roles in the phenomenology of CHS symptoms and signs have been identified with statistical significance from a small dataset.”
Thanks via #EthanRusso @Peter_Grinspoon @wodak - Could do with some book reports :-) / #CliffNotes #CannabisCommunity https://t.co/vVGUM1jzRH https://t.co/QlkUxtukMG
Jul 7, 2021 · 1 like · 46,427 followersView post →
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trppapers
@trp_papers · X
Cannabinoid Hyperemesis Syndrome Survey and Genomic Investigation https://t.co/JQPtgNNuWR https://t.co/qbO0pMW8Ul
Interesting given its a topic of some controversy among some in the cannabis community. “Cannabinoid Hyperemesis Syndrome Survey and Genomic Investigation”
Dr Ethan B. Russo, et al: https://t.co/NGIH5rboZ1
Patients are not tested for pesticide poisoning. There are those that believe patient genetics plays a role in CHS. (2022 Jun 6. doi: 10.1089/can.2021.0046).
Esrarı tekrar sıkıcı hale getirmek: Esrar ve kannabinoidlerin kimyası ...
Reddit
... 10.1089/can.2021.0046. Ve üründeki toksinler ölüme yol açabilir: https://pubmed.ncbi.nlm.nih.gov/3293934/. Ve bütün EVALI hikayesi. bizzle70. • ...
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