PubHawk
July 2021 PMID 34237248

SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19.

Alba Grifoni, John Sidney, Randi Vita, Bjoern Peters, Shane Crotty, Daniela Weiskopf, Alessandro Sette

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Mentions

125
Peak: 18 in May 2021
across 6 sources since May 2021

Extended reach

552,092
potential audience

Total likes

5,798

Video views

308,676

Mentions per month

May 2021 – Jul 2022

Where it's discussed

  • News76 articles
  • X / Twitter37 posts
  • Blogs4 articles
  • YouTube3 videos
  • Facebook3 posts
  • Reddit2 posts

AI synopsis

What people are saying

The group's tone and word choices emphasize the importance of the epitope diversity in immune response, with comments praising the broad T cell targeting as a 'game changer' for vaccine development. References to detailed data and implications demonstrate deep engagement and recognition of the research's significance.

AgreementModerate agreement

Most discussions acknowledge the significance of the study and its focus on T cell responses, supporting its positive findings.

InterestHigh interest

Participants show high curiosity by referencing multiple aspects like vaccine design, immune response, and variants effect.

EngagementModerate engagement

Posts analyze detailed data, such as the number of epitopes (>1,400), and discuss immune defense mechanisms, indicating active interest.

ImpactHigh impact

Posts highlight how this research influences vaccine strategies and understanding of immune protection, reflecting high perceived impact.

Abstract in brief

  • Numerous studies have been conducted over the past year to identify and analyze SARS-CoV-2 T cell epitopes, which are specific parts of the virus recognized by the immune system.
  • The research shows a strong link between the number of identified epitopes and the size of the virus proteins they come from, revealing key areas of the virus that trigger immune responses.
  • Overall, scientists identified about 1,400 different T cell epitopes across the virus, highlighting important regions that could influence vaccine development, cross-reactivity with other viruses, and how the virus might escape immune detection.
Read the full abstract

Top posts

Most liked on X and Bluesky
Cell Host & Microbe
@cellhostmicrobe · X

SARS-CoV-2 human T cell epitopes: Adaptive immune response against #COVID19. @SetteLab @Alba_Grifoni discuss #SARSCoV2-derived human CD4/CD8 #Tcell epitopes & immune response, w/insights for #vaccine design, cross-reactivity & escape monitoring of variants https://t.co/vuvpHChpkK https://t.co/Hn5PPrtrYC

Jul 15, 2021 · 8 likes · 4 shares · 27,517 followers View post →
Dr. Thomas Wilckens
@Thomas_Wilckens · X

We are not w/o defense against #variants! SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19 https://t.co/q9iSoDKb1K Slide via @SetteLab #coronavirus #covid19 #omicron #vaccine #vaccination #immunity #Tcells https://t.co/0nRCAFWhYV

Dec 10, 2021 · 7 likes · 2 shares · 6,814 followers View post →
La Jolla Institute
@ljiresearch · X

New in @cellhostmicrobe: SARS-CoV-2 Human T cell Epitopes: adaptive immune response against #COVID19 "This remarkable breadth of epitope repertoire has implications for vaccine design, cross-reactivity and for immune escape by SARS-CoV-2 variants." https://t.co/v2VxCzqCp1

May 26, 2021 · 6 likes · 4 shares · 6,045 followers View post →
La Jolla Institute
@ljiresearch · X

4. This broad T cell response makes it difficult for SARS-CoV-2 variants to acquire enough mutations to “escape” the body’s response against the virus. Read the full paper: https://t.co/v2VxCzqCp1 @cellhostmicrobe

May 28, 2021 · 4 likes · 6,045 followers View post →
Dr. Thomas Wilckens
@Thomas_Wilckens · X

2 Studies on significantly reduced protection from #Omicron #reinfection by antibodies post #coronavirus infection https://t.co/5HmwF3UzRJ & https://t.co/UyVOM0QbcB Read #Tcells SARS-CoV-2 human T cell epitopes: Adaptive immune response against #COVID19 https://t.co/tihuRXbqZH https://t.co/WEctt1XFAe

Dec 13, 2021 · 3 likes · 1 share · 6,814 followers View post →
Prof. Dr. Sanjeev Bagai
@BagaiDr · X

SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19: Cell Host & Microbe https://t.co/zZEpNWBcWr

Jul 22, 2021 · 2 likes · 34,755 followers View post →

All mentions

WCI
@WaltherCancerIn · X

RT @BagaiDr: SARS-CoV-2 Human T cell Epitopes: adaptive immune response against COVID-19. - ScienceDirect https://t.co/lvEdvgrcs4

Jul 29, 2022 · 1 share · 1,112 followers View post →
Kreuzritter
@MeinungFormen · X

RT @Thomas_Wilckens: 2 Studies on significantly reduced protection from #Omicron #reinfection by antibodies post #coronavirus infection ht…

Dec 13, 2021 · 1 share · 27 followers View post →
Dr. Thomas Wilckens
@Thomas_Wilckens · X

2 Studies on significantly reduced protection from #Omicron #reinfection by antibodies post #coronavirus infection https://t.co/5HmwF3UzRJ & https://t.co/UyVOM0QbcB Read #Tcells SARS-CoV-2 human T cell epitopes: Adaptive immune response against #COVID19 https://t.co/tihuRXbqZH https://t.co/WEctt1XFAe

Dec 13, 2021 · 3 likes · 1 share · 6,814 followers View post →
Isatou Sarr
@IsatouSarr4 · X

SARS-CoV-2 human T cell epitopes: Adaptive immune response against COV... https://t.co/E62t2EntzE

Dec 13, 2021 · 1 like · 32 followers View post →
Dr. Thomas Wilckens
@Thomas_Wilckens · X

RT @Thomas_Wilckens: We are not w/o defense against #variants! SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19…

Dec 11, 2021 · 2 shares · 6,814 followers View post →
Martie Turner
@martieinmiam · X

SARS-CoV-2 human T cell epitopes: Adaptive immune response against COV... https://t.co/WtKMf3VzTb

Dec 11, 2021 · 387 followers View post →
Maples the Syrup Frog
@Maples46014332 · X

RT @Thomas_Wilckens: We are not w/o defense against #variants! SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19…

Dec 10, 2021 · 2 shares · 2,800 followers View post →
Dr. Thomas Wilckens
@Thomas_Wilckens · X

We are not w/o defense against #variants! SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19 https://t.co/q9iSoDKb1K Slide via @SetteLab #coronavirus #covid19 #omicron #vaccine #vaccination #immunity #Tcells https://t.co/0nRCAFWhYV

Dec 10, 2021 · 7 likes · 2 shares · 6,814 followers View post →
Stephanie Cion
@StephanieCion · X

SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19. https://t.co/os3KQR7ENE

Dec 10, 2021 · 974 followers View post →
Prof. Dr. Sanjeev Bagai
@BagaiDr · X

SARS-CoV-2 Tcell epitopes:Adaptive immune resp vs COVID19:SARSCoV2-derived Tcell epitopes throughout SARSCoV2 proteome~btw no of epitopes & size Ag;CD4 & CD8 Tcell epitope,1,400 diff CoV2 epitope discrete immunodominant regions,breadth repertoire,X-reactv https://t.co/cUpnby4nY3

Dec 9, 2021 · 1 like · 34,755 followers View post →
JKK
@ConservJean · X

@ScottAdamsSays @AndreasShrugged Some infected from SARS1 still recording antibodies as well. https://t.co/8dj9eHadZu

Oct 5, 2021 · 2,512 followers View post →
Debunk the Funk
@Debunk_the_Funk · X

@Immetjes @rosepoptosis The figure in the article represents vaccine-induced immunity as being better than natural immunity. That was not just an artistic choice, it has been empirically demonstrated. https://t.co/VUZdLtCrgF

Sep 13, 2021 · 1 like · 33,238 followers View post →
Prof. Dr. Sanjeev Bagai
@BagaiDr · X

SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19: Cell Host & Microbe https://t.co/zZEpNWBcWr

Jul 22, 2021 · 2 likes · 34,755 followers View post →
はなお
@nntatatata · X

RT @cellhostmicrobe: SARS-CoV-2 human T cell epitopes: Adaptive immune response against #COVID19. @SetteLab @Alba_Grifoni discuss #SARSCoV2…

Jul 15, 2021 · 4 shares · 22 followers View post →
GustavoMarques
@gustavogarretRJ · X

RT @cellhostmicrobe: SARS-CoV-2 human T cell epitopes: Adaptive immune response against #COVID19. @SetteLab @Alba_Grifoni discuss #SARSCoV2…

Jul 15, 2021 · 4 shares · 45 followers View post →
Valerie Valeriano
@vallysue08 · X

RT @cellhostmicrobe: SARS-CoV-2 human T cell epitopes: Adaptive immune response against #COVID19. @SetteLab @Alba_Grifoni discuss #SARSCoV2…

Jul 15, 2021 · 4 shares · 235 followers View post →
Naomi Attar
@naomiattar · X

RT @cellhostmicrobe: SARS-CoV-2 human T cell epitopes: Adaptive immune response against #COVID19. @SetteLab @Alba_Grifoni discuss #SARSCoV2…

Jul 15, 2021 · 4 shares · 1,243 followers View post →
Cell Host & Microbe
@cellhostmicrobe · X

SARS-CoV-2 human T cell epitopes: Adaptive immune response against #COVID19. @SetteLab @Alba_Grifoni discuss #SARSCoV2-derived human CD4/CD8 #Tcell epitopes & immune response, w/insights for #vaccine design, cross-reactivity & escape monitoring of variants https://t.co/vuvpHChpkK https://t.co/Hn5PPrtrYC

Jul 15, 2021 · 8 likes · 4 shares · 27,517 followers View post →
NFTdose
@PaperbirdsH · X

New article: SARS-CoV-2 human T cell epitopes: adaptive immune response against COVID-19 https://t.co/JOIcKiKlKT #coronavirus #COVID19 #2019ncov https://t.co/9Qw7j6e7ja

Jul 9, 2021 · 302 followers View post →
La Jolla Institute
@ljiresearch · X

4. This broad T cell response makes it difficult for SARS-CoV-2 variants to acquire enough mutations to “escape” the body’s response against the virus. Read the full paper: https://t.co/v2VxCzqCp1 @cellhostmicrobe

May 28, 2021 · 4 likes · 6,045 followers View post →
Isatou Sarr
@IsatouSarr4 · X

SARS-CoV-2 Human T cell Epitopes: adaptive immune response against COVID-19. https://t.co/l1cvlV0kJQ

May 28, 2021 · 1 like · 32 followers View post →
Canadian Association For Biological Safety
@CABSACSB · X

SARS-CoV-2 Human T cell Epitopes: adaptive immune response against COV... https://t.co/6TUyVaK9W8

May 27, 2021 · 311 followers View post →
Scripps CHAVD
@Scripps_CHAVD · X

RT @ljiresearch: New in @cellhostmicrobe: SARS-CoV-2 Human T cell Epitopes: adaptive immune response against #COVID19 "This remarkable bre…

May 27, 2021 · 4 shares · 259 followers View post →
akiro
@akiroxx · X

RT @ljiresearch: New in @cellhostmicrobe: SARS-CoV-2 Human T cell Epitopes: adaptive immune response against #COVID19 "This remarkable bre…

May 27, 2021 · 4 shares · 378 followers View post →
Julia B.
@JuliaB_fitness · X

RT @ljiresearch: New in @cellhostmicrobe: SARS-CoV-2 Human T cell Epitopes: adaptive immune response against #COVID19 "This remarkable bre…

May 26, 2021 · 4 shares · 2,271 followers View post →
Prof. Dr. Sanjeev Bagai
@BagaiDr · X

SARS-CoV-2 Human T cell Epitopes: adaptive immune response against COVID-19. - ScienceDirect https://t.co/lvEdvgrcs4

May 26, 2021 · 1 like · 1 share · 34,755 followers View post →
Cell Host & Microbe
@cellhostmicrobe · X

RT @ljiresearch: New in @cellhostmicrobe: SARS-CoV-2 Human T cell Epitopes: adaptive immune response against #COVID19 "This remarkable bre…

May 26, 2021 · 4 shares · 27,517 followers View post →
La Jolla Institute
@ljiresearch · X

New in @cellhostmicrobe: SARS-CoV-2 Human T cell Epitopes: adaptive immune response against #COVID19 "This remarkable breadth of epitope repertoire has implications for vaccine design, cross-reactivity and for immune escape by SARS-CoV-2 variants." https://t.co/v2VxCzqCp1

May 26, 2021 · 6 likes · 4 shares · 6,045 followers View post →
Medical Science and Technology #earlytreatments
@MedicalScitech · X

In a new paper, scientists from La Jolla Institute for Immunology (LJI) bring together research findings from #COVID19 researchers around the world. The results are striking: human #Tcells can target more than 1,400 sites on the #SARSCoV2 #coronavirus. https://t.co/jJVWvgpPQZ https://t.co/MAZfmGRZfT

May 26, 2021 · 631 followers View post →
kai
@kai958531911 · X

SARS-CoV-2 Human T cell Epitopes: adaptive immune response against COV... https://t.co/nzPk2Tbd5X

May 25, 2021 · 1 like · 1 share · 267 followers View post →
Dr Anthony Martin
@AMAinsight · X

SARS-CoV-2 Human T cell Epitopes: adaptive immune response against COV... https://t.co/rZXywtnf3C

May 25, 2021 · 913 followers View post →
Nel
@NelsonSaf · X

@tickerguy “report analysis of SARS-CoV-2 human CD4 and CD8 T-cell epitope data compiled, identifying 1400 different reported SARS-CoV-2 epitopes and revealing discrete immunodominant regions of the virus and epitopes that are more prevalently recognized.” https://t.co/cLHlb8A8Aa

May 24, 2021 · 1 like · 166 followers View post →
G.Wenger
@bricolix · X

RT @NelsonSaf: @philippefroguel Je n’en suis pas aussi sur que ça. 2/3 me semble exagéré. https://t.co/cLHlb8A8Aa

May 24, 2021 · 1 share · 1,516 followers View post →
Nel
@NelsonSaf · X

@philippefroguel Je n’en suis pas aussi sur que ça. 2/3 me semble exagéré. https://t.co/cLHlb8A8Aa

May 24, 2021 · 1 share · 166 followers View post →
Nel
@NelsonSaf · X

@Laissonslespre1 Ceci est renforcé par le fait qu’une immunité naturelle est beaucoup plus robuste. Ainsi quand les “vaccins” disponibles ne se basent que sur la protéine de Spike, l’immunité naturelle est dirigée contre plus de 1400 épitopes viraux. https://t.co/cLHlb8A8Aa

May 24, 2021 · 2 likes · 166 followers View post →
Isatou Sarr
@IsatouSarr4 · X

SARS-CoV-2 Human T cell Epitopes: adaptive immune response against COVID-19. https://t.co/tM1sCrVC3f

May 24, 2021 · 1 like · 32 followers View post →
Dr Diego Mpia Elenge
@arztdiego · X

SARS-CoV-2 Human T cell Epitopes: adaptive immune response against COV... https://t.co/MpIb8QcVdA

May 23, 2021 · 1,443 followers View post →