September 2021 PMID 34312554

Tina Schmidt, Verena Klemis, David Schub, Janine Mihm, Franziska Hielscher, Stefanie Marx, Amina Abu-Omar, Laura Ziegler, Candida Guckelmus, Rebecca Urschel, Sophie Schneitler, Sören L Becker, Barbara C Gärtner, Urban Sester, Martina Sester

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Mentions

34
Peak: 6 in Jul 2021
across 5 sources since Jul 2021

Extended reach

345,478
potential audience

Total likes

58

Video views

1,163

Mentions per month

Jul 2021 – Nov 2025

Where it's discussed

  • X / Twitter14 posts
  • News13 articles
  • Facebook3 posts
  • YouTube2 videos
  • Instagram2 posts

AI synopsis

What people are saying

The discussions demonstrate agreement and interest through references to the study’s findings, such as mentions of stronger immune responses like higher antibody levels and T-cell responses. The tone often emphasizes the potential of heterologous vaccination to improve immunity, using words like 'interesting' and 'must consider,' reflecting both curiosity and support for the research.

AgreementModerate agreement

Most discussions support the findings of heterologous vaccination's effectiveness, using positive language like 'interesting' and referencing strong immune responses.

InterestHigh interest

Many debates show high curiosity about the immune response and vaccine strategies, indicating strong engagement and relevance.

EngagementHigh engagement

Posts reference specific scientific results and express opinions on vaccine efficacy, demonstrating deep involvement and critical thinking.

ImpactModerate impact

The discussions highlight the potential influence of heterologous vaccination strategies on public health and vaccination policies, showing moderate impact.

Abstract in brief

  • Heterologous priming with the ChAdOx1 nCoV-19 vector vaccine followed by mRNA booster shots (BNT162b2 or mRNA-1273) is recommended in Germany, and a study showed it leads to stronger immune responses compared to using only the vector vaccine.
  • In a study with 96 healthy adults, heterologous vaccination resulted in higher levels of spike-specific IgG, neutralizing antibodies, and CD4 T cells compared to homologous vector boosts and showed comparable results to homologous mRNA regimens.
  • While both homologous regimens showed greater reactogenicity post-priming, the heterologous mRNA booster was well tolerated, indicating it induces strong immune

Top posts

Most liked on X and Bluesky
Dr. Javier Flores
@farmacotips · X

Aquí les dejo un artículo en pubmed muy interesante. https://t.co/y3S0rVIalB

Nov 5, 2021 · 21 likes · 5 shares · 207,002 followers View post →
David El-Qutob
@DavidQutob · X

Schmidt, T., Klemis, V., Schub, D. et al. Immunogenicity and reactogenicity of heterologous ChAdOx1 nCoV-19/mRNA vaccination. Nat Med (2021). https://t.co/kDje3S5DjM

Aug 4, 2021 · 11 likes · 1,577 followers View post →
الدكتور كمال أيوب
@DRKAMALAYOUB · X

دراسة مطمئنة للاشخاص الذين تلقو جرعة لقاحهم الاولى من استرازينيكا وجرعة لقاحهم الثانية من لقاح فايزر حيث وجدت ان اخذ لقاحين مختلفين آمن وفعال . https://t.co/ObGuXa6LU8

Jul 29, 2021 · 6 likes · 6 shares · 24,032 followers View post →
Mike Clark
@mrc7cam · X

@VercesiCesare @kallmemeg @vivax74 @UKHSA @DHSCgovuk @SMHopkins @cstewartb @EricTopol @GuptaR_lab Except it would appear that heterologous immunisation, 2xAZ+mRNA, may give rise to qualitatively and quantitatively better CD4 and CD8 T-cell responses in addition to high titres of nAb. https://t.co/4z18sf5Ung

Jan 1, 2022 · 3 likes · 586 followers View post →
fede
@fd_aballay · X

https://t.co/WHHZ8f0FtA

Aug 14, 2021 · 1 like · 3,904 followers View post →
Bella Ciao Enjoyer
@Timmyctc · X

@brockiesner @Letthatsinkin44 @WomenPostingLs https://t.co/wSLnhKz3rP

Nov 22, 2021 · 1 like · 631 followers View post →

All mentions

Mike Clark
@mrc7cam · X

@VercesiCesare @kallmemeg @vivax74 @UKHSA @DHSCgovuk @SMHopkins @cstewartb @EricTopol @GuptaR_lab Except it would appear that heterologous immunisation, 2xAZ+mRNA, may give rise to qualitatively and quantitatively better CD4 and CD8 T-cell responses in addition to high titres of nAb. https://t.co/4z18sf5Ung

Jan 1, 2022 · 3 likes · 586 followers View post →
Bella Ciao Enjoyer
@Timmyctc · X

@brockiesner @Letthatsinkin44 @WomenPostingLs https://t.co/wSLnhKz3rP

Nov 22, 2021 · 1 like · 631 followers View post →
Isaac Freire
@IsakiFreire · X

RT @farmacotips: Aquí les dejo un artículo en pubmed muy interesante. https://t.co/y3S0rVIalB

Nov 9, 2021 · 5 shares · 721 followers View post →
FreddyYagual37
@FYagual37 · X

RT @farmacotips: Aquí les dejo un artículo en pubmed muy interesante. https://t.co/y3S0rVIalB

Nov 5, 2021 · 5 shares · 167 followers View post →
Killer-B
@rsklnikoff96 · X

RT @farmacotips: Aquí les dejo un artículo en pubmed muy interesante. https://t.co/y3S0rVIalB

Nov 5, 2021 · 5 shares · 129 followers View post →
Dr. Javier Flores
@farmacotips · X

Aquí les dejo un artículo en pubmed muy interesante. https://t.co/y3S0rVIalB

Nov 5, 2021 · 21 likes · 5 shares · 207,002 followers View post →
fede
@fd_aballay · X

https://t.co/WHHZ8f0FtA

Aug 14, 2021 · 1 like · 3,904 followers View post →
David El-Qutob
@DavidQutob · X

Schmidt, T., Klemis, V., Schub, D. et al. Immunogenicity and reactogenicity of heterologous ChAdOx1 nCoV-19/mRNA vaccination. Nat Med (2021). https://t.co/kDje3S5DjM

Aug 4, 2021 · 11 likes · 1,577 followers View post →
Nawal Nawaf AlSadoon
@Nawal_9_ · X

RT @DRKAMALAYOUB: دراسة مطمئنة للاشخاص الذين تلقو جرعة لقاحهم الاولى من استرازينيكا وجرعة لقاحهم الثانية من لقاح فايزر حيث وجدت ان اخذ لقاح…

Jul 29, 2021 · 6 shares · 1,955 followers View post →
﮼Ahoud
@_O_H_D · X

RT @DRKAMALAYOUB: دراسة مطمئنة للاشخاص الذين تلقو جرعة لقاحهم الاولى من استرازينيكا وجرعة لقاحهم الثانية من لقاح فايزر حيث وجدت ان اخذ لقاح…

Jul 29, 2021 · 6 shares · 139 followers View post →
عبدالناصر أبوسرير خبير تربوي - حساب شخصي
@abusareer · X

RT @DRKAMALAYOUB: دراسة مطمئنة للاشخاص الذين تلقو جرعة لقاحهم الاولى من استرازينيكا وجرعة لقاحهم الثانية من لقاح فايزر حيث وجدت ان اخذ لقاح…

Jul 29, 2021 · 6 shares · 402 followers View post →
خالد الحسن
@KhaledHAlHassan · X

RT @DRKAMALAYOUB: دراسة مطمئنة للاشخاص الذين تلقو جرعة لقاحهم الاولى من استرازينيكا وجرعة لقاحهم الثانية من لقاح فايزر حيث وجدت ان اخذ لقاح…

Jul 29, 2021 · 6 shares · 765 followers View post →
د. بادي العنزي
@bqalenazi · X

RT @DRKAMALAYOUB: دراسة مطمئنة للاشخاص الذين تلقو جرعة لقاحهم الاولى من استرازينيكا وجرعة لقاحهم الثانية من لقاح فايزر حيث وجدت ان اخذ لقاح…

Jul 29, 2021 · 6 shares · 102,014 followers View post →
الدكتور كمال أيوب
@DRKAMALAYOUB · X

دراسة مطمئنة للاشخاص الذين تلقو جرعة لقاحهم الاولى من استرازينيكا وجرعة لقاحهم الثانية من لقاح فايزر حيث وجدت ان اخذ لقاحين مختلفين آمن وفعال . https://t.co/ObGuXa6LU8

Jul 29, 2021 · 6 likes · 6 shares · 24,032 followers View post →
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