August 2021 PMID 34354960

Tick Saliva and the Alpha-Gal Syndrome: Finding a Needle in a Haystack.

Surendra Raj Sharma, Shahid Karim

Mentions

77
Peak: 4 in Nov 2021
across 5 sources since Jul 2021

Extended reach

289,662
potential audience

Total likes

10,538

Video views

257,060

Mentions per month

Jul 2021 – Jun 2025

Where it's discussed

  • News51 articles
  • X / Twitter14 posts
  • YouTube7 videos
  • Blogs3 articles
  • Facebook2 posts

AI synopsis

What people are saying

The discussions reflect an overall agreement that the article sheds light on how tick saliva proteins lead to alpha-gal allergies, with examples like mentions of the biological process, ongoing uncertainties, and real-life impacts such as dietary restrictions and the need for further research. Tone shifts between curiosity and concern, emphasizing the importance and potential implications of this scientific work.

AgreementModerate agreement

Most discussions acknowledge the article's findings, especially regarding the role of tick saliva proteins in causing alpha-gal syndromes.

InterestHigh interest

Participants show high curiosity, particularly about the connection between tick bites, alpha-gal, and severe allergies, indicated by specific references to risks and mechanisms.

EngagementModerate engagement

Several comments reference detailed scientific mechanisms and current uncertainties, demonstrating a moderate level of in-depth engagement.

ImpactModerate impact

The discussions highlight the significance of understanding tick saliva's role in allergies, suggesting the research could influence how tick-borne allergies are addressed.

Abstract in brief

  • The article discusses the role of tick saliva in facilitating the transmission of tickborne diseases and its connection to Alphagal Syndrome (AGS), a food allergy caused by saliva proteins decorated with a sugar molecule called galactose.
  • AGS is characterized by an immune response, specifically IgE antibodies targeting the gal antigen found in tick saliva from species such as the Lone Star tick, but the exact immune mechanisms are not yet fully understood.
  • Understanding how tick bites induce a gal-specific IgE response is crucial for developing new treatments, and current research focuses on the biology of tick saliva and its role in AGS.]

Top posts

Most liked on X and Bluesky
UltimApe
@ultimape · X

@Fast_cove @Grimhood babesiosis https://t.co/OORGr0vMgl

Jan 8, 2022 · 2 likes · 6,693 followers View post →
tune
@keisuke4713 · X

ダニの唾液とα-Gal症候群https://t.co/HlKCeTZKnu 世界的⬆️ 宿主とダニの要因:可能性 抗α-gal IgEの力価が高いが、発症しない人がいる https://t.co/EkcQl7oR3a

Mar 23, 2023 · 2 likes · 3,741 followers View post →
Ferg
@christoferguson · X

@Portia72307 https://t.co/qwkB13E8UE

May 9, 2022 · 1 like · 4,864 followers View post →
TBC United
@TBCU2018 · X

@LymeScience @VectorCollector @theticklab @ssurendraraj @lordofthetick @DETickTalk See also - https://t.co/qfswRiJu2L

Apr 13, 2022 · 1 like · 859 followers View post →
Abdulsalam Adegoke, DVM, Ph.D
@AdegokeDVM_PhD · X

Tick Saliva and the Alpha-Gal Syndrome: Finding a Needle in a Haystack https://t.co/loqnq8ADxS

Jul 21, 2021 · 1 like · 467 followers View post →
Fernpick
@Fernpick · X

@LynneSaunt @LCrealfood @RDValerie Everything you ever wanted to know about it. Seems about 3% of population, much of that is unnoticed but still important to keep clear of ticks. You can still eat poultry,fish, shellfish. https://t.co/rDUuAY5aTL

Jul 21, 2022 · 1 like · 436 followers View post →

All mentions

Understanding the Red Meat Allergy Spread by Ticks

Scientists have identified alphagal syndrome, a red meat allergy caused by tick bites, over the past decade. While research advances, some doctors remain unaware. Hosted by Hank Green, this video explores the science…

SciShow · Jan 10, 2024 233,987 views
HorseGirl in Pearls
@SwtCharlemaigne · X

@WaltxPrincess @VanyaWright @DCS1441 and it is from a protein in the Lone Star tick saliva, which then causes the allergy to the sugar molecule. So it's still caused by a protein. https://t.co/kZggCVoNG0

Dec 30, 2024 · 5,646 followers View post →
HorseGirl in Pearls
@SwtCharlemaigne · X

@VanyaWright @WaltxPrincess @DCS1441 sorry just reading fully what you wrote It actually is from a protein in the saliva of the Lone Star tick that CAUSES a reaction to the sugar molecule. https://t.co/kZggCVoNG0

Dec 30, 2024 · 5,646 followers View post →
tune
@keisuke4713 · X

ダニの唾液とα-Gal症候群https://t.co/HlKCeTZKnu 世界的⬆️ 宿主とダニの要因:可能性 抗α-gal IgEの力価が高いが、発症しない人がいる https://t.co/EkcQl7oR3a

Mar 23, 2023 · 2 likes · 3,741 followers View post →
Fernpick
@Fernpick · X

@LynneSaunt @LCrealfood @RDValerie Everything you ever wanted to know about it. Seems about 3% of population, much of that is unnoticed but still important to keep clear of ticks. You can still eat poultry,fish, shellfish. https://t.co/rDUuAY5aTL

Jul 21, 2022 · 1 like · 436 followers View post →
Ferg
@christoferguson · X

@Portia72307 https://t.co/qwkB13E8UE

May 9, 2022 · 1 like · 4,864 followers View post →
TBC United
@TBCU2018 · X

@LymeScience @VectorCollector @theticklab @ssurendraraj @lordofthetick @DETickTalk See also - https://t.co/qfswRiJu2L

Apr 13, 2022 · 1 like · 859 followers View post →
Margo Courtney
@marmotmargaret · X

Watch out for ticks! They can transport the sugar molecule alpha-gal into the body, triggering a reaction that produces severe allergies to red meat. There’s no treatment- my mom was bit by a lone- star tick and hasn’t had a steak for years! #ees028 https://t.co/fMHPoBgw2N

Feb 9, 2022 · 1 like · 7 followers View post →
UltimApe
@ultimape · X

@Fast_cove @Grimhood babesiosis https://t.co/OORGr0vMgl

Jan 8, 2022 · 2 likes · 6,693 followers View post →
Holly C. Tuten
@VectorCollector · X

RT @FrontCellInfect: New Research: Tick Saliva and the Alpha-Gal Syndrome: Finding a Needle in a Haystack https://t.co/XV1vydkLTW #cellinfe…

Sep 8, 2021 · 4 shares · 2,467 followers View post →
Surendra Raj Sharma
@SurendraRajSha3 · X

RT @FrontCellInfect: New Research: Tick Saliva and the Alpha-Gal Syndrome: Finding a Needle in a Haystack https://t.co/XV1vydkLTW #cellinfe…

Sep 2, 2021 · 4 shares · 3 followers View post →
urban fatbiker
@urbanfatbiker · X

@PhilipFDaniels1 @VirusesImmunity More we learn, more science changes. "..still unclear how tick acquires and presents α-gal... ...various evidence suggests α-gal is possibly originating from tick itself." [The Origin of α-gal in Tick Saliva] We're barely 10 years in. A work in progress. https://t.co/04XLMzCKQv

Aug 8, 2021 · 1,402 followers View post →
food_allergy_feed
@FoodAllergyNCBI · X

Tick Saliva and the Alpha-Gal Syndrome: Finding a Needle in a Haystack https://t.co/YLGQZNdcGH

Aug 6, 2021 · 225 followers View post →
Surendra Raj Sharma
@ssurendraraj · X

RT @FrontCellInfect: New Research: Tick Saliva and the Alpha-Gal Syndrome: Finding a Needle in a Haystack https://t.co/XV1vydkLTW #cellinfe…

Jul 30, 2021 · 4 shares · 124 followers View post →
Abdulsalam Adegoke, DVM, Ph.D
@AdegokeDVM_PhD · X

Tick Saliva and the Alpha-Gal Syndrome: Finding a Needle in a Haystack https://t.co/loqnq8ADxS

Jul 21, 2021 · 1 like · 467 followers View post →