Pharmacoeconomics November 2021 PMID 34368939

How Much Does It Cost to Research and Develop a New Drug? A Systematic Review and Assessment.

Michael Schlander, Karla Hernandez-Villafuerte, Chih-Yuan Cheng, Jorge Mestre-Ferrandiz, Michael Baumann

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Mentions

106

Peak: 11 in Mar 2025

across 5 sources since Aug 2020

Extended reach

486,613

potential audience

Total likes

16,051

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418,040

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Aug 2020 – Apr 2025

Where it's discussed

News66 articles
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AI synopsis

What people are saying

The collective discussions reveal a balanced view of the publication, with participants referencing its insights into the high and variable costs of drug research, as seen in comments about billion-dollar R&D expenses and the importance of transparency. The tone varies from analytical to concerned, illustrating active deliberation on the economic and societal significance of the findings.

AgreementModerate agreement

Most discussions acknowledge the high costs and complexity of drug development, which aligns with the publication's findings emphasizing cost variability and uncertainty.

InterestHigh interest

Posts demonstrate high interest by referencing the systematic review, exploring topics like Big Pharma, the economic aspects of research, and public perceptions, reflecting active engagement with the subject.

EngagementModerate engagement

Some comments go beyond mere sharing, discussing the implications on healthcare, funding, and societal perceptions, showing active participation and reflection.

ImpactModerate impact

The discussions have a moderate perceived impact, as users express concern about drug costs, the role of the pharmaceutical industry, and the potential influence of the research on policy debates.

Abstract in brief

The systematic review examined published estimates of research and development (R&D) costs for bringing a new drug to market, finding a wide range from $161 million to $454 billion, with higher costs for cancer drugs.
The study assessed the quality of these cost estimates based on how the data were collected, considered variability sources, and included cost components, but found no improvement in estimate reliability over time.
Overall, the review highlights that R&D costs are highly uncertain and there is no definitive or universally accepted average cost for developing a new drug.]

Read the full abstract

All mentions

Real Pharmaceutical Scandals and Industry Oversight Explained

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The Factors Behind High Cost of New Drugs and Development Challenges

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You have just discovered the organ-on-a-chip project developed by students from the University of São Paulo, highlighting the reliance on these innovative microdevices for more accurate drug testing. Explore how they…

Vegantec · Oct 23, 2021 420 views

Loony Raven

@loonyraven.bsky.social · Bluesky

2v2 Das »End-Video-90er-Medley: I like to proof it! [FF: Factman【Maddin" Schneider

Apr 28, 2025 View post →

Loony Raven

@loonyraven · X

Im »zeitlichen« (3d?) Zusammenhang mit @Karl_Lauterbach + der ePAT-Situation April 2025 ist die WDH von »MaiThinkX: Big Pharma« heute Nacht (28./29.04.) »interessant«. Auf »GEZ-Medium«?! Why? Das »End-Video-Medley: I'd like to proof it! Ff« = Mega!!!

Apr 28, 2025 · 492 followers View post →

Helgo

@helgol · X

Teetrinken mit Mai. Immer besser als Wahl von Merz. https://t.co/hEctvZ6I5x

Mar 4, 2025 · 3,232 followers View post →

Waldläuferin

@waldlaeuferin.bsky.social · Bluesky

youtu.be/PjGZ8ORHZc8?... GIER

Mar 4, 2025 · 22 likes · 11 shares View post →

Poppy Phoenix_embroidery

@poppy_phoenixda · X

https://t.co/qQWfszvE6H Ja, wir müssen vielleicht Teile der Medizin von der Börse holen und Medikamente (vor allem der alternativ Medizin) besser Prüfen, aber die Schulmedizin ist besser als Bleiche und nix für die #AFD

Mar 4, 2025 · 62 followers View post →

Andreas Schöpf

@andreasschoepf.bsky.social · Bluesky

Wie immer sehr sehenswert, das neue Video von Mai Thi Nguyen-Kim: Geldgier. #Pharmaindustrie #BigPharma youtu.be/PjGZ8ORHZc8?... @maithinkx.bsky.social

Mar 3, 2025 · 1 like View post →

Don van Win

@donvanwin.mastodon.social.ap.brid.gy · Bluesky

https://www.youtube.com/watch?v=PjGZ8ORHZc8

Mar 3, 2025 View post →

☢️

@DrakoonLP · X

Liked on YouTube: BIG PHARMA | Das Milliardengeschäft https://t.co/Lc7FYeOWfi

Mar 2, 2025 · 114 followers View post →

OMG Torsten

@tngraessler · X

Wie geil ist bitteschön die neue Folge von @maithinkx?!? @maithi_nk #SchöneSonndaaach

Mar 2, 2025 · 1 like · 606 followers View post →

Haroun

@HHerdick57816 · X

Zeer interessant. Over 'Big Pharma". Zij is chemicus. Voor diegenen, die het Duits machtig zijn. https://t.co/9dba3MkWJo

Mar 2, 2025 · 139 followers View post →

Adolfs Enkel

@AdolfsErbe · X

Nimmst Du auch so viele Pillen? https://t.co/VadHcglRLV

Mar 2, 2025 · 20 followers View post →

Dieter Brunzel

@DieterBrunzel · X

BIG PHARMA | Das Milliardengeschäft https://t.co/o1nIfCVbtP via @YouTube Danke Mailab ,das du auch mal die Schattenseiten ansprchst ,das gehört eben dar zu!!!

Mar 2, 2025 · 54 followers View post →

Mirko von Hein

@vonHeinMirko · X

Aug 19, 2024 · 66 followers View post →

Quintin Pope

@QuintinPope5 · X

@matthew_d_green @GarettJones @james_dedir If you look at the actual past of drug development, then you'd predict that drugs actually become **more** expensive per drug to develop. E.g., https://t.co/vsT9KPG69U https://t.co/w0X8L3V6Ge

Jul 14, 2024 · 2,988 followers View post →

RaisedRight120

@RaisedRight120 · X

@margyusc @Heritage https://t.co/CwpisvU0t2 It costs up to $5Billion PER DRUG for research and development - and many don’t make it past their clinical trials.

Mar 7, 2024 · 1,062 followers View post →

Phys.org Chemistry

@physorg_chem · X

Organ-on-a-chip models allow researchers to conduct studies closer to real-life conditions @ConversationEDU https://t.co/GBMMDKXkIZ https://t.co/ALQRzuitDH

Jan 11, 2023 · 7,202 followers View post →

Dan

@MrDanNovotny · X

@donwinslow https://t.co/Hg9KeXTRC5 $161 million to $4.5 billion to develop a new medication. Impose price controls and pharmaceutical development stops in its tracks. No new treatments for Alzheimer's, cancer, MS, Parkinson's, etc. Keep talking.

Oct 18, 2022 · 1,414 followers View post →

Лея

@KattieBanned · X

@oneflewbytheby @LeilaniDowding I am talking exactly about Big Pharma and you're talking nonsense. Every pharmaceutical company needs investment as developing of medicine is extremely expensive. Don't argue about the topic you totally ignorant about. https://t.co/VOg7nDLdVQ

Aug 27, 2022 · 179 followers View post →

LawLoreG

@LawLoreG · X

RT @3sbien: ¿Cuánto cuesta investigar y desarrollar un nuevo fármaco? Una revisión y evaluación sistemáticas. 《 desde $ 161 millones hast…

Jun 6, 2022 · 3 shares · 16,162 followers View post →

MARIA TAPIA

@MaRosaTapiaEc · X

RT @3sbien: ¿Cuánto cuesta investigar y desarrollar un nuevo fármaco? Una revisión y evaluación sistemáticas. 《 desde $ 161 millones hast…

Jun 5, 2022 · 3 shares · 1,027 followers View post →

π Pi π

@TornCurtainPI · X

RT @3sbien: ¿Cuánto cuesta investigar y desarrollar un nuevo fármaco? Una revisión y evaluación sistemáticas. 《 desde $ 161 millones hast…

Jun 5, 2022 · 3 shares · 11,422 followers View post →

Carlos

@3sbien · X

¿Cuánto cuesta investigar y desarrollar un nuevo fármaco? Una revisión y evaluación sistemáticas. 《 desde $ 161 millones hasta $ 4.54 mil millones (2019 US $) https://t.co/9kKDr59TFi

Jun 5, 2022 · 5 likes · 3 shares · 6,724 followers View post →

Órgão em Chip

@orgaoemchip · X

Oct 9, 2021 · 2 likes · 11 followers View post →

Frank S. David

@Frank_S_David · X

Haven’t read this yet, but the topic of pharma R&D costs is catnip for me, so I’m looking forward! Article: https://t.co/QHj3t5Ok3w https://t.co/3OFqAOg75v

Aug 15, 2021 · 1 like · 7,309 followers View post →

MeowX

@leninwtigger · X

RT @sagisapi: How Much Does It Cost to Research and Develop a New Drug? A Systematic Review and Assessment | SpringerLink https://t.co/iZK8…

Aug 12, 2021 · 1 share · 609 followers View post →

Salamanca-Pinzón S.G.

@sagisapi · X

How Much Does It Cost to Research and Develop a New Drug? A Systematic Review and Assessment | SpringerLink https://t.co/iZK8budk8w

Aug 12, 2021 · 1 like · 1 share · 585 followers View post →

Shan Jiang

@ShanJiangHE · X

RT @JorgeMestreFerr: If you are interested and want to know more, have a look at our paper “How Much Does It Cost to Research and Develop a…

Aug 11, 2021 · 2 shares · 212 followers View post →

Kareem El-Fass BSc, PharmD, MSc

@kareemelfass · X

https://t.co/ZOAshhRmot

Aug 11, 2021 · 1,257 followers View post →

Chris Carswell

@PECjournal · X

RT @JorgeMestreFerr: If you are interested and want to know more, have a look at our paper “How Much Does It Cost to Research and Develop a…

Aug 11, 2021 · 2 shares · 2,386 followers View post →

Jorge Mestre-Ferrand

@JorgeMestreFerr · X

Aug 11, 2021 · 3 likes · 2 shares · 701 followers View post →

Chris Carswell

@PECjournal · X

How much does it cost to research and develop a new drug? https://t.co/ygaNh6xeNn https://t.co/Tce4f5yGEc

Aug 10, 2021 · 2,386 followers View post →

VegaVortexCN

@cn_vega · X

@thecolj @billshortenmp @YaThinkN https://t.co/gYMOYISpZ3 https://t.co/accDK6qHue https://t.co/BpIobh1jpN https://t.co/9it2QWNNLr Here are some of the sources I used. From most of the stuff I have looked at, most of the "rushing" is actually the paperwork part that approves the next step

Aug 31, 2020 · 91 followers View post →

How Much Does It Cost to Research and Develop a New Drug? A Systematic Review and Assessment.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Real Pharmaceutical Scandals and Industry Oversight Explained

The Factors Behind High Cost of New Drugs and Development Challenges

Human Organ Chips: Advancements and Implications for Drug Testing

Drug Development Process from Lab to Patient: Key Steps Explained

Advancements in Human Organ Chips for Drug Testing Validation