@DrAkhilX
Lipid Metabolism.
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Jan 2024 – Nov 2025Where it's discussed
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X / Twitter200 posts
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Bluesky199 posts
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YouTube3 videos
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News2 articles
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What people are saying
The overall tone reflects genuine interest, with comments highlighting how lipid metabolism influences conditions like Alzheimer’s, cancer, and neurodegenerative diseases, exemplified by mentions of genes like Pnpla2 and ABCA7, along with references to potential therapies. The words and tone emphasize scientific curiosity and recognition of potential health benefits, indicating a community engaged in advancing and applying knowledge in lipid metabolism.
Most discussions acknowledge the importance of lipid metabolism in health and disease, supporting the article's relevance.
Many posts show high curiosity, referencing detailed mechanisms and potential therapeutic targets, indicating strong engagement.
The social discussions involve technical details like specific genes and pathways, demonstrating active participation and curiosity in research implications.
While some recognize the potential for clinical applications, many posts focus on progressing scientific understanding, suggesting moderate perceived impact.
Abstract in brief
- Lipid metabolism refers to the processes by which the body digests, absorbs, and uses fats for energy and other vital functions.
- It involves breaking down lipids into components like fatty acids and glycerol, then converting these into energy or storing them for future use.
- Proper regulation of lipid metabolism is crucial for maintaining overall health and preventing conditions like obesity, diabetes, and cardiovascular diseases.]
Top posts
Most liked on X and Bluesky[Just for clarity, this is a joke. I am a scientist but I don't work on either developing therapies to make you look like your 'sona, nor do I work in lipid metabolism and adipose distribution on the body. But you know... science is still very important!!]
I am most excited to welcome 2 new Research Assistants to our lab; Sarvesh Rajkumar from @BrownUniversity and Eunsoo Hyun from @Yale to support the projects on lipid metabolism and aging. https://t.co/Rw3qf66wGw
#3 Scientific Tweet for @BioProtocol and @Aubrai_ The role of lipid metabolism in aging, lifespan regulation, and age related disease - In mice: A ketogenic diet (KD) produces ketone bodies (BHB, acetoacetate, acetone) when liver glycogen is depleted. KD extends lifespan and https://t.co/XVQ0bf6AzO https://t.co/D5toUhm5kK
Regulation of lipid metabolism is a primordial function of STING https://t.co/DjxpUIPQh5
CRP is a high-sensitivity biomarker of systemic inflammation. Even mild elevations predict metabolic dysfunction, poor glucose regulation, impaired lipid metabolism, endothelial stress, and reduced nervous-system resilience. In my approach, CRP is non-negotiable because you
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Comprehensive Metabolism Resources for Learning
This video presents free metabolism resources curated for your learning journey. Explore metabolic charts, graphics, and playlists, including insights into amino acid metabolism, which is vital for protein production…
Lipid Metabolism and Fatty Acid Synthesis Processes
This video explores lipid metabolism, focusing on how the body digests, absorbs, and utilizes fats, highlighting the importance of proper regulation to maintain health and prevent diseases.
Lipid Catabolism and Regulation with Emphasis on Beta-Oxidation
This video explores lipid digestion, mobilization, and transport, focusing on beta-oxidation and the regulation of fat metabolism. Proper lipid regulation is vital for energy production and overall health.
RT @atranscendedman: Researchers analyzed blood from 277 COVID-19 patients and found that SARS-CoV-2 disrupts ion channels and lipid metabo…
RT @atranscendedman: Researchers analyzed blood from 277 COVID-19 patients and found that SARS-CoV-2 disrupts ion channels and lipid metabo…
Researchers analyzed blood from 277 COVID-19 patients and found that SARS-CoV-2 disrupts ion channels and lipid metabolism, affecting pathways like cholesterol regulation and brain signaling. They identified 17 drugs that could target these changes. www.sciencedirect.com/science/arti...
Researchers analyzed blood from 277 COVID-19 patients and found that SARS-CoV-2 disrupts ion channels and lipid metabolism, affecting pathways like cholesterol regulation and brain signaling. They identified 17 drugs that could target these changes. https://t.co/LHb5304N6a
https://t.co/yIoxYObJ5v
RT @KrimeeraPharma: @DrAkhilX
Here, the atherogenic index of plasma (AIP), a sensitive index of lipid metabolism disorders, was associated with an increased risk of female infertility risk in US adults, particularly in younger women. https://t.co/StC70T3aND
@SomerwilTara @Chaddadbod @ketosavage If you get morning sunlight = beta oxidation, then yes, you will have a working lipid metabolism. And if you are fat adapted then yes it will work for everyone. Your oppinion doesn't change biophysics or biochemistry
RT @KrimeeraPharma: @DrAkhilX
RT @SEICannabinoide: Ahora le toca a Ramon-Duaso C que nos habla de “ASTROGLIAL LIPID METABOLISM: A LINK BETWEEN CANNABINOID DRUGS AND ALZH…
Altered Lipid Metabolism in the Vaginal Wall of Women With Pelvic Organ Prolapse: A Targeted Lipidomics Study #FASEBJ #MassSpec faseb.onlinelibrary.wiley.com/doi/10.1096/...
RT @KrimeeraPharma: @DrAkhilX
RT @KrimeeraPharma: @DrAkhilX
RT @merichyoztyurk: I’ve been involved in science communication since 2012, and I’ve learned the most while writing for @ASBMB Today. My l…
RT @KrimeeraPharma: @DrAkhilX
RT @KrimeeraPharma: @DrAkhilX
RT @KrimeeraPharma: @DrAkhilX
@DrAkhilX
Ahora le toca a Ramon-Duaso C que nos habla de “ASTROGLIAL LIPID METABOLISM: A LINK BETWEEN CANNABINOID DRUGS AND ALZHEIMER DISEASE?” https://t.co/0xQlg9929c
RT @merichyoztyurk: I’ve been involved in science communication since 2012, and I’ve learned the most while writing for @ASBMB Today. My l…
Excellent review article by Prof. Shengxi Wu’s team in Advanced Neurology highlights how lipid metabolism dysregulation drives #Parkinson’s disease via α-synuclein aggregation, mitochondrial dysfunction & #neuroinflammation. Read Freely: https://t.co/yfkEfyLkAO #Neuroscience https://t.co/Ux10KYkn0V
RT @MetabolitesMDPI:
I’ve been involved in science communication since 2012, and I’ve learned the most while writing for @ASBMB Today. My latest piece will be my last for a bit as I take a short break. I’ll return to science communication soon with fresh energy! Here it is
RT @idisbaib:
https://t.co/jqI5ezdL7q
RT @cdrjournal:
România: *ApoM & Klotho preserve nitric oxide bioavailability, lipid metabolism, & antioxidant defense *MGP modulates vascular calcification & adipose remodeling *dp-ucMGP is linked to vascular stiffness & renal decline *Eating natto carboxylates dp-ucMGP https://t.co/LdXHuQno3b
Swiss Cheese Gene Is Important for Intestinal Barrier, Microbiome, and Lipid Metabolism Regulation in Drosophila Gut #Drosophila
Oligodendrocyte lineage cells dysfunction in depression: early life stress, adolescent vulnerability and the emerging role of lipid metabolism https://t.co/E8bp2ShICz
Oligodendrocyte lineage cells dysfunction in depression: early life stress, adolescent vulnerability and the emerging role of lipid metabolism https://t.co/E8bp2Sigs7
RT @BGarcialab: This year we will be presenting two oral talks on Friday 28th November: @IreneGManzanar1 with the talk "MODELING CANNABIS-I…
This year we will be presenting two oral talks on Friday 28th November: @imanzanaressierra.bsky.social with the talk "MODELING CANNABIS-INDUCED PSYCHOTIC-LIKE STATES IN MICE" and @carlarduaso.bsky.social with "ASTROGLIAL LIPID METABOLISM: A LINK BETWEEN CANNABINOID DRUGS AND ALZHEIMER DISEASE?".
This year we will be presenting two oral talks on Friday 28th November: @IreneGManzanar1 with the talk "MODELING CANNABIS-INDUCED PSYCHOTIC-LIKE STATES IN MICE" and @CarlaRDuaso with "ASTROGLIAL LIPID METABOLISM: A LINK BETWEEN CANNABINOID DRUGS AND ALZHEIMER DISEASE?".
Prof. Nurit Argov-Argaman is a leading expert in milk-lipid metabolism and lactation physiology, uncovering how maternal biology shapes milk composition and health outcomes. We are proud to have her as part of the Lavin Food Center academic team. https://t.co/7CWk5Vlnpx
RT @Pluchinolab: Regulation of lipid metabolism is a primordial function of STING https://t.co/DjxpUIPQh5
RT @Pluchinolab: Regulation of lipid metabolism is a primordial function of STING https://t.co/DjxpUIPQh5
Asif Mohmmed works on several P. falciparum proteins that affect lipid metabolism, ER mitochondria contact sites and mitochondria division. @CSIR_CDRI https://t.co/JRq6nj7xeb
RT @Pluchinolab: Regulation of lipid metabolism is a primordial function of STING https://t.co/DjxpUIPQh5
Tesamorelin and MOTS-c are drawing attention for their potential roles in metabolic research. Both may offer insights into lipid metabolism, glucose regulation, and mitochondrial function within controlled research settings. https://t.co/HrJ0EH9N1L
RT @Pluchinolab: Regulation of lipid metabolism is a primordial function of STING https://t.co/DjxpUIPQh5
@MadAtTheGalaxy Training does differ in the EU vs Canada or US, so not sure expertise is the same. Laws may differ as well. And my claims have little to do with the DNA, more with ongoing adverse effects, drug interactions, lipid metabolism, cell biology etc....
RT @Pluchinolab: Regulation of lipid metabolism is a primordial function of STING https://t.co/DjxpUIPQh5
The first challenge came up in a conversation about a project: how can I check gene sets across different databases (e.g., GO terms, KEGG Pathways, ...) involved in specific processes, like iron processing or lipid metabolism?
@Pluchinolab Nice study! The role of STING in regulating lipid metabolism adds a new dimension to our understanding of this protein beyond its involvement in the immune response. Could this open pathways for therapeutic interventions in metabolic diseases? I'm keen to see more longitudinal
Phospholipase A2 from Porcine Pancreas Catalog Number: B2025850 (1 mg) PLA2 from porcine pancreas is an enzyme that hydrolyzes phospholipids, vital for cell membranes. It is involved in lipid metabolism and has a catalytic site influenced by calcium ions. https://t.co/NyKZ1S8Ymb
RT @Pluchinolab: Regulation of lipid metabolism is a primordial function of STING https://t.co/DjxpUIPQh5
RT @Pluchinolab: Regulation of lipid metabolism is a primordial function of STING https://t.co/DjxpUIPQh5
RT @Pluchinolab: Regulation of lipid metabolism is a primordial function of STING https://t.co/DjxpUIPQh5
Interventions that promote healthy #aging differ in their effectiveness between individuals. This #Celegans study shows that the effect of a pro- #longevity intervention can be strongly influenced by early-life #splicing factor activity & metabolic landscape @plosbiology.org
Breakthrough in gastric cancer! #HKUMed research led by Prof. Alan Wong, Prof. Leung Suet-yi, and Prof. Helen Yan discovered that nerve-driven lipid metabolism promotes tumour growth. More info: www.sbms.hku.hk/news/press-r...
How lipid metabolism shapes sperm development https://www.newsbeep.com/ie/160432/ Sperm cells are among the most specialized in the body, designed for a single purpose: fertilization. Each carries…
How lipid metabolism shapes sperm development https://www.europesays.com/ie/200989/ Sperm cells are among the most specialized in the body, designed for a single purpose: fertilization. Each carries…
How lipid metabolism shapes sperm development https://www.newsbeep.com/nz/154443/ Sperm cells are among the most specialized in the body, designed for a single purpose: fertilization. Each carries…
Regulation of lipid metabolism is a primordial function of STING https://t.co/DjxpUIPQh5
Interventions that promote healthy #aging differ in their effectiveness between individuals. This #Celegans study shows that the effect of a pro- #longevity intervention can be strongly influenced by early-life #splicing factor activity & metabolic landscape @plosbiology.org
@demystifysci CTP is apparently involved in some lipid metabolism but idk about that. The real answer to your question tho is that mitochondria have ATP synthase and that's the molecule that makes all of these.
@newstart_2024 But cancer is a disease where DNA mutations exist that allow the cell to grow in a manner that is not natural. This leads to dysfunctional metabolism. In part, it has crazy lipid metabolism and the signaling is way off with regards to normal lipid-mediated signaling.
Interventions that promote healthy #aging differ in their effectiveness between individuals. This #Celegans study shows that the effect of a pro- #longevity intervention can be strongly influenced by early-life #splicing factor activity & metabolic landscape @plosbiology.org
Xiang Ren et al. from Huazhong University of Science and Technology find that RPGRORF15 mutations disrupt lysosomal lipid metabolism in retinal pigment epithelium cells and cause retinitis pigmentosa. https://t.co/JobRmsaf0Y https://t.co/Mod35uCcOm
Blocking cholesterol metabolic pathways in gastric cancer cells reduced tumor growth by 65% in mice, highlighting lipid metabolism as a promising target for future precision therapies. doi.org/g9428b
Microscopy-Guided Spatial Proteomics Reveals Novel Proteins at the Mitochondria-Lipid Droplet Interface and Their Role in Lipid Metabolism www.biorxiv.org/content/10.1...
Exercise enhances fatty acid composition in the longissimus dorsi muscle of Sunit lambs and improves dressing percentage by supporting better digestion, absorption and lipid metabolism. A clear link between activity and quality. Read full article at : https://t.co/RQRzczlSWJ https://t.co/LRn1HrX91f
On the front cover of issue 23 of Food & Function: Green tea prepared via the daily infusion method prevents non-alcoholic fatty liver disease by targeting intestinal lipid absorption, hepatic lipid metabolism and gut microbiota composition. De-Xing Hou et al. pubs.rsc.org/en/content/a...
RT @TejasTekk: Choline is not popularly discussed on social media, so sharing a detailed post on choline. Choline is an essential nutrient…
Choline is not popularly discussed on social media, so sharing a detailed post on choline. Choline is an essential nutrient for proper liver, muscle, and brain functions as well as for lipid metabolism and cellular membrane composition and repair. Humans can produce small
TAp73 mediates anti-tumor immunity through regulation of lipid metabolism in the lung tumor microenvironment https://t.co/dMQJ69xFm5 #biorxiv_cancer
TAp73 mediates anti-tumor immunity through regulation of lipid metabolism in the lung tumor microenvironment https://www.biorxiv.org/content/10.1101/2025.11.21.689807v1
TAp73 mediates anti-tumor immunity through regulation of lipid metabolism in the lung tumor microenvironment https://www.biorxiv.org/content/10.1101/2025.11.21.689807v1
Successful endodontic treatment improves glucose and lipid metabolism: a longitudinal metabolomic study ... https://t.co/N1k9qAlDnL
New Questions and Answers Included 100 Correct 2024 CPPS 303 - Lipid Metabolism 1 New Questions and Answers ( Included ) 100% Correct What leads to the development of metabolic diseases? Answer: Dietary lipid over- loads https://t.co/XFsDCeFH3F https://t.co/Uj4D2Puvfb
RT @5HTskeptic: “Oxidative-Inflammatory Modulation of Skin Lipid Metabolism by Linoleic Acid” https://t.co/gzx1IUX3c0 SKIN FOOD solves this
New publication! USC researchers used our 3D InSight™ Human Liver Microtissues to study PFAS effects with single-cell sequencing. They found cell-type, donor, and sex-specific responses, plus disrupted lipid metabolism and immune signaling, advancing PFAS liver research. Publication linked below.
“Oxidative-Inflammatory Modulation of Skin Lipid Metabolism by Linoleic Acid” https://t.co/gzx1IUX3c0 SKIN FOOD solves this https://t.co/bkYM6rfxoU
@CaryKelly11 1. Mouse UVcancer studies don’t translate cleanly to humans.The classic papers showed that certain high-PUFA chow amplified UV tumor formation in hairless lab mice.Those mice have radically different skin biology, immune response, lipid metabolism, and UV sensitivity vs to humans
RT @Womens_onlin: トリキュラーの禁忌で脂質代謝異常のある患者とは #トリキュラー #オンライン診療 #ミニピル #スリンダ #ノルレボ #PMS #レボノルゲストレル #ラベルフィーユ #マーベロン #ファボワール #アフターピル #…
RT @Womens_onlin: トリキュラーの禁忌で脂質代謝異常のある患者とは #トリキュラー #オンライン診療 #ミニピル #スリンダ #ノルレボ #PMS #レボノルゲストレル #ラベルフィーユ #マーベロン #ファボワール #アフターピル #…
RT @Womens_onlin: トリキュラーの禁忌で脂質代謝異常のある患者とは #トリキュラー #オンライン診療 #ミニピル #スリンダ #ノルレボ #PMS #レボノルゲストレル #ラベルフィーユ #マーベロン #ファボワール #アフターピル #…
@SamaHoole vitamin D interferes with the entire lipid metabolism. It's only used to counter effects of allowed ergot & smutballs in grain that causes fetal absorption. Rickets was rediscovered and renamed as fortification was announced a success. (McCune Albright's syndrome, Albright's
トリキュラーの禁忌で脂質代謝異常のある患者とは #トリキュラー #オンライン診療 #ミニピル #スリンダ #ノルレボ #PMS #レボノルゲストレル #ラベルフィーユ #マーベロン #ファボワール #アフターピル #ピル #afterpill #telemedicine #pill https://t.co/TqoV8PPp7b
RT @xiahepublishing:
https://t.co/9li7rXGl1r
RT @jasmeet481: CRP is a high-sensitivity biomarker of systemic inflammation. Even mild elevations predict metabolic dysfunction, poor gluc…
@FrontImmunol This is an intriguing area of study! Lipid metabolic reprogramming plays a substantial role in shaping the immune responses within the tumor microenvironment. How do you think this could influence future immunotherapy approaches? Could targeting lipid metabolism offer new
Endothelial Cells in Liver Zonation & Regeneration
RT @ZdenekVrozina: SARS-CoV-2 doesn’t produce a classic toxin. But it reprograms our lipid metabolism so deeply that the cell enters a toxi…
RT @ZdenekVrozina: SARS-CoV-2 doesn’t produce a classic toxin. But it reprograms our lipid metabolism so deeply that the cell enters a toxi…
New Research: Bidirectional regulation of lipid metabolism and the tumor microenvironment: new perspectives from mechanism to therapy https://t.co/hpQU2HmZm8 #FrontiersIn #Immunology
@BowTiedBiotech Interesting perspective on treating arteries as an immune entity rather than just a mechanical issue. The interplay between inflammation and lipid metabolism could indeed open new therapeutic doors. What roles do T-cells and macrophages play in immune atherogenesis from your
RT @jasmeet481: CRP is a high-sensitivity biomarker of systemic inflammation. Even mild elevations predict metabolic dysfunction, poor gluc…
@idkactual @mixxpilled Many peptides influence lipid metabolism by modulating pathways like lipolysis or adipogenesis, not a direct dissolving action. It's about cellular signaling.
RT @Outdoctrination: Nattokinase has multiple other effects that prevent the plaque buildup process. ➥ Reduces key inflammatory pathways (…
RT @jasmeet481: CRP is a high-sensitivity biomarker of systemic inflammation. Even mild elevations predict metabolic dysfunction, poor gluc…
RT @jasmeet481: CRP is a high-sensitivity biomarker of systemic inflammation. Even mild elevations predict metabolic dysfunction, poor gluc…
@anonemus349832 @SamaHoole Ronald Krauss holds a professorship in Pediatrics at UCSF, but is board-certified in internal medicine and endocrinology, with expertise in lipid metabolism and CVD risk (UCSF Profiles). He has disclosed funding from dairy and beef associations (Wikipedia; JACC 2020). ApoB is
RT @jasmeet481: CRP is a high-sensitivity biomarker of systemic inflammation. Even mild elevations predict metabolic dysfunction, poor gluc…
New Full Questions and Answers Included 100 Correct 2024 CPPS 303 - Liver Lipid Metabolism New Full Questions and Answers ( Included ) 100% Correct Where are bile acids synthesized? Answer: The liver Where are bile acids stored? https://t.co/8nulyfdsdW https://t.co/Px02mZAKpc
RT @jasmeet481: CRP is a high-sensitivity biomarker of systemic inflammation. Even mild elevations predict metabolic dysfunction, poor gluc…
CRP is a high-sensitivity biomarker of systemic inflammation. Even mild elevations predict metabolic dysfunction, poor glucose regulation, impaired lipid metabolism, endothelial stress, and reduced nervous-system resilience. In my approach, CRP is non-negotiable because you
RT @jasmeet481: CRP is a high-sensitivity biomarker of systemic inflammation. Even mild elevations predict metabolic dysfunction, poor gluc…
RT @jasmeet481: CRP is a high-sensitivity biomarker of systemic inflammation. Even mild elevations predict metabolic dysfunction, poor gluc…
RT @jasmeet481: CRP is a high-sensitivity biomarker of systemic inflammation. Even mild elevations predict metabolic dysfunction, poor gluc…
CRP is a high-sensitivity biomarker of systemic inflammation. Even mild elevations predict metabolic dysfunction, poor glucose regulation, impaired lipid metabolism, endothelial stress, and reduced nervous-system resilience. In my approach, CRP is non-negotiable because you
Desaturase-dependent secretory functions of hepatocyte-like cells control systemic lipid metabolism during starvation in Drosophila #Drosophila
A lots, can’t even remember all, Prof Onyeagala courses,Medical microbiology, MSc, Functional disorder,biochemistry of lipid metabolism https://t.co/KIesTDXeAM
RT @ghotamis: I am most excited to welcome 2 new Research Assistants to our lab; Sarvesh Rajkumar from @BrownUniversity and Eunsoo Hyun fro…
RT @nick_krontiris: Here, the atherogenic index of plasma (AIP), a sensitive index of lipid metabolism disorders, either alone or combined…
Impact of annual health check-ups on improvement in hypertension and abnormalities of glucose and lipid metabolism ->Nature | #Health | More from Lil Dr Glen EcoChat at BigEarthData.ai
@dr_ericberg Grounded in morning sunlight to start beta-oxidation which revs up the lipid metabolism, without it, it doesn't happen
Published a new piece on Biohackers Media, Chemerin Receptors Unveil Lipid Metabolism Mechanisms #science #longevity #biohacking
New structural insights into chemerin receptors reveal how GPR1 and CMKLR1 coordinate to regulate lipid metabolism and immune cell trafficking, offering potential targets for metabolic disease therapies. doi.org/hbb5th
Here, the atherogenic index of plasma (AIP), a sensitive index of lipid metabolism disorders, either alone or combined with obesity-related indicators (particularly AIP-CVAI), was associated with an increased risk of incident cardiovascular disease, especially in diabetes https://t.co/sL8f9ebGGE
Loss of Nuclear TDP-43 Impairs Lipid Metabolism in Microglia-Like Cells #NeuroDegeneration
Discovery of Lipid Metabolism Networks as Key Pathways in Breast Cancer via Genomic Data Integration and WGCNA https://t.co/a7OwATYnQ1
Excited to share my first-author study showing how cannabis cigarette smoking, combined with an obesogenic environment, disrupts multi-organ bioactive lipid metabolism and inflammation-resolution pathways. https://t.co/FfyqVzHAda
One of the results of ocean warming and acidification is the changes in lipid metabolism occurring in algal populations. Along with tropic cascade of nutrients, there’s more to fish than Omega/DHAs. Soon enough, omega will be lab synthesised as a sustainable source. https://t.co/u9pcqGTXvI
Sex-specific effects of GnIH on lipid metabolism in SD rats Phys&Beh
RT @HemostasisToday: Amelia Carro Hevia Spotlights New Review: Lipid Metabolism in Women @maryamkavousi https://t.co/PL5MfTJoUX #Atheros…
RT @interactivefly: Lago Solis, B., Koch, R., Nagoshi, E. (2025).. Circadian clock-independent ultradian rhythms in lipid metabolism in the…
Check out this new position in my lab! We investigate lipid metabolism in the brain and are looking for a new team member to join us. If you know someone who is a great fit, please feel free to share! https://t.co/ijlDimZNVv
I am most excited to welcome 2 new Research Assistants to our lab; Sarvesh Rajkumar from @BrownUniversity and Eunsoo Hyun from @Yale to support the projects on lipid metabolism and aging. https://t.co/Rw3qf66wGw
Also in Issue 21: - Research Highlights on force transduction and lipid metabolism - Mole's Comedia III - A tribute to Günther Gerisch - A Hypothesis article on hormones and RNP granules - Sphingolipids and methionine metabolism Review https://t.co/ZH7ei5CZjD https://t.co/dGLL1ZBnZq
Also in Issue 21: - Research Highlights on force transduction and lipid metabolism - Mole's Comedia III - A tribute to Günther Gerisch - A Hypothesis article on hormones and RNP granules - Sphingolipids and methionine metabolism Review journals.biologists.com/jcs/issue/13...
In #AnimalMicrobiome
A new fluorescent probe enables real-time visualization of metabolic activity in individual lipid droplets, revealing diverse breakdown rates in liver cancer cells and advancing lipid metabolism research. doi.org/hbbw6j
@vinitiwari1.bsky.social & Mikael Simons review the relationship between lipid #metabolism & CNS #inflammation & how disruptions in this interplay contribute to neurological disorders rupress.org/jem/article/...
@biorxivpreprint.bsky.social Regulation of lipid metabolism is a primordial function of STING @igmm-montpel.bsky.social www.biorxiv.org/content/10.1... @nadinelaguette.bsky.social
Identification and tissue-specific expression of genes involved in lipid metabolism in broad-snouted caiman zslpublications.onlinelibrary.wiley.com/doi/10.1111/... #crocodilians #physiology #metabolism #lipids @amcell.bsky.social @elissazcameron.bsky.social @wileyecology.bsky.social
Targeting lipid metabolism in neurodegenerative diseases: From experimental to clinical www.metabolismjournal.com/article/S002...
Bone, Muscle & Beyond webinar series: Lipids metabolism in bone health - Join the October ECTS webinar on November 20, 2025, featuring Elisabeth Rendina-Ruedy, University of Oklahoma Health Campus, presenting on "Lipid Metabolism in Bone Health." The live webinar is free. See more: buff.ly/pbq1roB
Chrysanthemum morifolium extract improves metabolic dysfunction-associated fatty liver disease by regulating lipid metabolism ->Nature | #Health #Disease | More from Lil Dr Glen EcoChat at BigEarthData.ai
Regulation of lipid metabolism is a primordial function of STING https://www.biorxiv.org/content/10.1101/2025.11.17.688879v1
Regulation of lipid metabolism is a primordial function of STING https://www.biorxiv.org/content/10.1101/2025.11.17.688879v1
Lago Solis, B., Koch, R., Nagoshi, E. (2025).. Circadian clock-independent ultradian rhythms in lipid metabolism in the Drosophila fat body. J Biol Chem, 301(6):110245 www.jbc.org/article/S002...
How do RNA viruses manage plant lipid metabolism at high temperatures? Read more https://bit.ly/4nt5Bgc
Many of these Mtb genes were associated with lipid metabolism, so we orthogonally validated these observations by tracking Mtb acquisition and storage of lipids using established techniques and found that Mtb readily forms intracellular lipid inclusions in mouse but not human macrophages
Amino acid and lipid metabolism: an overview, focusing on key points youtu.be/luUpILOx-5k
Research shows that C3G may help reduce oxidative stress, limit neuroinflammation, support brown fat thermogenesis, regulate glucose and lipid metabolism, and interact with gut microbiota to form additional beneficial compounds.
#OTILT estrogen increases a persons risk for gallstones because it effects lipid metabolism by increasing hepatic secretion of cholesterol into the bile @sophiaylee.bsky.social @yoon-jun.bsky.social @bwdionne.bsky.social @jeffpears0n.bsky.social pmc.ncbi.nlm.nih.gov/articles/PMC...
I wish I could go back 20 years jn time and tell BSc student me how cool lipid metabolism and metabolism regulation is! Basic stuff seen through the eyes of an experienced researcher!
Based on extensive mouse studies demonstrating miR-432 exacerbates #obesity induced dysregulation of glucose and lipid metabolism, the authors propose miR-342 antagonist to treat cardiometabolic disorders diabetesjournals.org/diabetes/art... ada.silverchair-cdn.com/ada/content_...
‘Using an in vivo mouse model, we further demonstrate the interactions of a representative pesticide-gut microbiota pair & verify the inflammation-inducing effects of pesticide exposure on the host, mediated by microbially dysregulated lipid metabolism’
Turicibacter in gut microbiome may help mice (and possibly people) lean by modifying the host lipid metabolism. www.nature.com/articles/d41...
The genome reveals a diverse array of biosynthetic capabilities, including over 750 genes involved in lipid metabolism across 12 KEGG pathways.
Transcriptomic analyses revealed that DAF-16 and HLH-30 cooperate to induce expression of lipid metabolism genes, including vps-34 and bec-1, that support lysosome membrane remodeling.
In our newest paper published in @natcomms.nature.com, we show that DAF-16/FOXO and HLH-30/TFRB promote healthy aging, in part, by activating lipid metabolism genes that remodel lysosomes into tubular networks (more in comments below). www.nature.com/articles/s41...
Effect of exercise on multi-compartment lipid metabolism in murine models fed an obesogenic diet using non-targeted LC/MS #FrontNutr www.frontiersin.org/journals/nut...
New review to read! #Bioenergetics and #lipid metabolism in #Alzheimer's disease: From cell biology to systemic health.
Several of the introgressed genes have clear functional relevance: THRB affecting visual development, the Pacific variant may enhance vision under the red-shifted light of the Baltic’s shallows. SEC16B, involved in lipid metabolism; possibly improving energy storage during long, cold winters.
Join the ECTS webinar, featuring Elisabeth Rendina-Ruedy, University of Oklahoma Health Campus, presenting on "Lipid Metabolism in Bone Health." Time: Thursday, 20 November, 16.00 CET
Mendelian Randomization using UK Biobank data indicates that branched-chain amino acids (BCAAs) may causally affect lipid metabolism. Raina Jia et al. propose understanding tissue-specific pathways of BCAA induced lipid dysregulation could inform their use as clinical targets. buff.ly/4CaaJWq
Bioenergetics and lipid metabolism in Alzheimer's disease: From cell biology to systemic health
Our new paper reveals that chronic active MS lesions feature CD8⁺ T cell niches with lipid-laden, inflamed microglia. IFN-γ drives cholesterol buildup, linking dysregulated lipid metabolism to inflammation and meurodeg. Check it out @cp-immunity.bsky.social www.sciencedirect.com/science/arti...
Higher miR-33a & miR-122 levels in T2DM patients with metabolic syndrome correlate with lipid metabolism issues. #MicroRNAs #MetabolicSyndrome www.rimpacts.com/rd/p?c=10126...
Recently, a rare pediatric case revealed a role for Site1-protease in development and lipid metabolism. Lijun Xia & team generated mouse models, discovering S1P/SREBP2-mediated cholesterol biosynthesis is necessary for lymphatic vascular development: insight.jci.org/articles/vie...
Understand abetalipoproteinemia and its impact on lipid metabolism. #Biochemistry #USMLE #MetabolicDisorder #MedicalEducation #LipidTransport
Differential effects of Nordic and Vegetarian diets on lipid metabolism, gut microbiome and cardiometabolic risk factors: A multi-omic perspective from a randomized clinical intervention trial https://www.medrxiv.org/content/10.1101/2025.11.03.25337885v1
• Cross-species comparison reveals links between lipoprotein metabolism & longevity • High HDL & efficient cholesterol transport support longevity • Molecular pathways AMPK, mTOR, SIRT integrate lipid metabolism with aging regulation • CR & lipid-modifying therapies improve healthspan
Study: Recent evolution in human intestines shows changes in immune barrier and lipid metabolism compared to chimpanzees, mice. PMID:40674448, Science 2025, @ScienceMagazine https://doi.org/10.1126/science.adr8628 #Medsky #Pharmsky #RNA #ASHG #ESHG
ADAR RNA editing for cardiovascular disease: Targeting B4GALT1 to modulate lipid metabolism through reduced galactosyltransferase activity https://www.biorxiv.org/content/10.1101/2025.10.30.685343v1
ADAR RNA editing for cardiovascular disease: Targeting B4GALT1 to modulate lipid metabolism through reduced galactosyltransferase activity https://www.biorxiv.org/content/10.1101/2025.10.30.685343v1
The study's findings have significant implications for understanding the fundamental mechanisms underlying lipid metabolism and signaling pathways.
We provide mechanistic insight linking key biological risk factors for AD to molecular regulation in the LC of lipid metabolism, calcium regulation, oxidative stress, and autophagy, processes broadly relevant to neurodegeneration.
Tesamorelin Another GHRH analog shown to help reduce visceral fat and improve lipid metabolism. It supports cellular energy and body composition goals tied to healthy aging.
Metabolism: Hormonal shifts can affect insulin sensitivity, lipid metabolism, and body fat distribution, contributing to an increased risk of metabolic syndrome and type 2 diabetes.
Yerba mate and green tea Interesting. Studies show matcha can improve lipid metabolism in rats anyway. Careful with the cocktails though booze may negate benefits. https://share.consumers.app/web/news/fkJ51PYd
Comprehensive transcriptomic analysis of larval and adult liver tissues revealed widespread dysregulation of biological processes involved in lipid metabolism, energy homeostasis, and inflammatory responses.
Piperonyl butoxide induces a unique gene expression of both detoxification and lipid metabolism genes and is independent of nutrition, microbiota, and genetic background #Drosophila
Cool story. Emphasizes the role of CD8 T cells at the chronic active lesion edge and the cross-talk with microglia. IFN-signaling and dysregulated lipid metabolism take center-stage. www.cell.com/immunity/ful...
Spatially resolved atlas of chronic active multiple sclerosis lesions reveals CD8 T cell niches enriched with inflamed microglia (⬆️IFN responses, ⬇️lipid metabolism) @cp-immunity.bsky.social @lenaspieth.bsky.social www.cell.com/immunity/ful...
Lipid Metabolism classification of gliomas #SingleCell
#Tau PET/CT
Impact of aging on gut-lung-adipose tissue interactions and lipid metabolism during influenza infection in mice www.nature.com/articles/s41...
PROFOLUS: Obesity usually raises heart risk. But not always. New research shows one gene can alter fat and lipid metabolism and reduce cardiovascular danger.
#ImmunologyNews A new study has uncovered a surprising link between lipid metabolism and the immune system’s ability to deliver its lethal cargo…#research #science Read more here: www.immunopaedia.org.za/breaking-new...
Olive Oil, Lipid Metabolism, and the Real Story Behind the Mediterranean Diet and Alzheimer’s • Could a Mediterranean diet reduce Alzheimer’s risk for some people more than others? I unpack a new study that shows why those with ApoE4 should (or should not) pay attention to these new data...
The results indicate that lipid metabolism-related genes (LMRGs) & certain cholesterol biosynthetic enzymes, such as 3β-hydroxysteroid Δ24-reductase gene (DHCR24), are broadly downregulated in AD patients.
FABP5 regulates ether lipid metabolism to ameliorate atopic dermatitis https://www.biorxiv.org/content/10.1101/2025.10.24.684205v1
FABP5 regulates ether lipid metabolism to ameliorate atopic dermatitis https://www.biorxiv.org/content/10.1101/2025.10.24.684205v1
Mechanistic insights revealed that improving mitochondrial function enhanced hepatic lipid metabolism and gluconeogenesis, elevated glucose and lipid handling capacity in skeletal muscle, and promoted thermogenesis in brown adipose tissue. www.sciencedirect.com/science/arti...
Homeostasis of glucose and lipid metabolism during physiological responses to a simulated hypoxic high altitude environment ->Nature | More from Lil' Dr Glen EcoChat at BigEarthData.ai
Comparative transcriptomics reveals differential carbohydrate and lipid metabolism in roots and nodules of Rhizobia-Inoculated alfalfa (Medicago sativa L.) | BMC Plant Biology | Full Text
Announcing the newest addition to our editorial board in the Cell & Molecular Biology section - Dr. Ainara Gonzalez-Cabodevilla! We're thrilled to have Dr. Gonzalez-Cabodevilla's expertise in lipid metabolism, lipid droplet biology, endothelial cell biology, lipoproteins, and atherosclerosis.
Moving to brown adipose tissue to learn about function of VW8A function in lipid metabolism from Habib Hayat.
(RCM) Lipidomic Profiling Reveals Phenotype‐Specific Metabolic Signatures in Obese and Hyperuricemic Children: ABSTRACT Objective This study aims to investigate the phenotype-specific alterations in lipid metabolism among children with obesity,… #RapidCommunMassSpectrom #MassSpecRSS
Lipid metabolism associated with efficacy of metronomic capecitabine and camrelizumab in gastrointestinal cancer: an exploratory clinical trial #BMCMed #MassSpec bmcmedicine.biomedcentral.com/articles/10....
Lipid Metabolism Remodeling in Human Cardiomyocyte Differentiation and Maturation https://www.biorxiv.org/content/10.1101/2025.10.21.682321v1
Lipid Metabolism Remodeling in Human Cardiomyocyte Differentiation and Maturation https://www.biorxiv.org/content/10.1101/2025.10.21.682321v1
[Just for clarity, this is a joke. I am a scientist but I don't work on either developing therapies to make you look like your 'sona, nor do I work in lipid metabolism and adipose distribution on the body. But you know... science is still very important!!]
Infection rewires sugar & lipid metabolism ⬇️ Fecundity, ⬆️ parasite growth & longevity
(BioRxiv All) The yeast peroxisomal proteome at absolute quantitative scale: Peroxisomes are dynamic organelles vital for lipid metabolism and redox homeostasis. In Saccharomyces cerevisiae, the expression of peroxisomal proteins is tightly regulated in response to metabolic… #BioRxiv #MassSpecRSS
Regulation of lipid metabolism in Spodoptera frugiperda by the symbiotic bracovirus of the gregarious parasitoid Cotesia ruficrus journals.plos.org/plospathogen...
Inhibition of CGRP receptor ameliorates AD pathology by reprogramming lipid metabolism through HDAC11/LXRβ/ABCA1 signaling #NeuroDegeneration
Inhibition of CGRP receptor ameliorates AD pathology by reprogramming lipid metabolism through HDAC11/LXRβ/ABCA1 signaling https://www.biorxiv.org/content/10.1101/2025.10.17.683079v1
Dietary cholesterol-fat type combinations and carbohydrate and lipid metabolism in rats and mice
We show that anemones absorb #lipid nanoparticles directly from seawater, stimulating their #metabolism. Details, and potential applications for #coral reef restoration and aquaculture, in our new preprint! www.biorxiv.org/content/10.1... #science #marinebiology #symbiosis #proteomics
Uncover the genetic roots of abdominal aortic aneurysm (AAA) and discover how PCSK9 - a key player in lipid metabolism - could unlock new prevention and treatment strategies for this life...
MTCH2 modulates CPT1 activity to regulate lipid metabolism of adipocytes | Nature Communications www.nature.com/articles/s41...
MTCH2 Controls CPT1 to Regulate Adipocyte Lipids In a groundbreaking study published in Nature Communications, researchers have unveiled a pivotal mechanism behind lipid metabolism regulation in adipocytes, centered around the mitochondrial protein MTCH2 and its influence on CPT1 activity. This…
Determination of metabolic markers for lipid metabolism disorders and liver injury recovery via PXR/FXR-CYP7A1 regulation by Folium Ginkgo #JPBA #MassSpec www.sciencedirect.com/science/arti...
Congrats to Dr. Richard Bazinet, recipient of the Western University 2025 Alumni of Distinction Award! With over 200 publications he has made compelling and impactful progress towards the advancement of brain lipid metabolism research! www.uwo.ca/fhs/fns/abou...
Huge milestone for the #RasheedLab, celebrating our first publication!
ER stress can mess with #fat cells! This new intramuscular adipocyte model reveals how cellular stress impacts adipogenesis and lipid #metabolism
Nanomedicine targeting PPAR in adipose tissue macrophages improves lipid metabolism and obesity-induced metabolic dysfunction Science Advances www.science.org/doi/10.1126/...
Other preclinical studies have seen knocking down GCGR has loads of deleterious downstream results. Abnormal electrolytes, increased blood pressure, abnormal lipid metabolism etc etc. we see it in humans too. Elevated cholesterol & BP, liver derangements.
In a new study, experts discovered that older people produce a glycosylated protein called apoplipoprotein D (ApoD), which is involved in lipid metabolism and inflammation, at much higher levels than in younger people
I couldn’t be prouder of Liuyu (Elle) Peng from my lab who submitted her PhD thesis yesterday. Her research was a tour de force in developing a multi-omics workflow for global lipid-protein ‘interactome’ analysis to understand the role of aberrant lipid metabolism in multisystem Mitochondial disease
Scientists at the University of Alberta showed how ectosomes facilitate the spread of misfolded alpha synuclein, and how lipid metabolism could be a therapeutic target to limit this spread in #neurodegenerative diseases. Learn more on the blog
Individual lipid alterations at the origin of neuronal Ceramide Synthase defects #CerS. #PLoSGenet @unibonn.bsky.social #ThieleLab; #BauerLab; #SobaLab; #brain; #lipid #metabolism; shorturl.at/O6LBn
RT @HEP_Journal: Original Article Human-induced pluripotent stem cell–based hepatic modeling of lipid metabolism–associated TM6SF2-E167K v…
@Callawaygolfpro ### Dave Feldman's Views on High Total Cholesterol Dave Feldman, a software engineer turned citizen scientist and founder of the Citizen Science Foundation, is best known for his research on lipid metabolism, particularly in the context of low-carb, high-fat (LCHF) or ketogenic
@Tonmapu @BioProtocol @Aubrai_ The post discusses the role of lipid metabolism in aging and lifespan regulation, highlighting the ketogenic diet's effects on extending lifespan and healthspan in mice and improving cognition in a 71-year-old woman with Alzheimer's. It also raises questions about the mechanisms
@0x_mcp @BioProtocol @Aubrai_ lipid metabolism sits at the heart of energy mate
@ccejw شكلك تدرسين lipid metabolism ولا انا غلطانه ؟
Unlock the Secrets to Living Longer! #shorts https://t.co/EPayFreMC0 via @YouTube The secret to a long life is to choose your parents wisely. Supercentenarians have genetic variants that promote good lipid metabolism & an immune system that ages well. 15% of the population did
Rosmarinic acid regulates lipid accumulation through lipid metabolism and anti-inflammatory https://t.co/OJiPhNiCwQ
@Tonmapu @BioProtocol @Aubrai_ interesting insights on lipid metabolism's impact on aging and cognition in mice and humans highlighting potential benefits of ketogenic diet.
Sex-Based Differences in Long-Term Lipid Metabolism, Inflammation and Stress Regulation After Non-Severe Paediatric Burns https://www.medrxiv.org/content/10.1101/2025.09.23.25336456v1
Sex-Based Differences in Long-Term Lipid Metabolism, Inflammation and Stress Regulation After Non-Severe Paediatric Burns https://t.co/IWAWJ4Vfov #medRxiv
Scientists at the University of Alberta showed how ectosomes facilitate the spread of misfolded alpha synuclein, and how lipid metabolism could be a therapeutic target to limit this spread in #neurodegenerative diseases. Learn more on the blog
@cell_club Steric repulsion in cellular membranes is a fascinating concept! It seems to regulate protein dynamics from the ER to lipid droplets through spatial constraints, influencing cellular lipid metabolism. How do you think such intrinsic properties can be leveraged for therapeutic
@Tonmapu @BioProtocol @Aubrai_ Lipid metabolism is crucial for understanding longevity and combating age-related diseases.
@Tonmapu @BioProtocol @Aubrai_ It is very exciting to see the important role lipid metabolism plays in regulating longevity and age-related diseases!
RT @IsabelRamirezRD: Some of the same elements we discuss in @remissionbiome and work on modulating M116’s microbiome may promote anti-in…
#3 Scientific Tweet for @BioProtocol and @Aubrai_ The role of lipid metabolism in aging, lifespan regulation, and age related disease - In mice: A ketogenic diet (KD) produces ketone bodies (BHB, acetoacetate, acetone) when liver glycogen is depleted. KD extends lifespan and https://t.co/XVQ0bf6AzO https://t.co/D5toUhm5kK
@greenisbright Some studies link stinging nettle to potential weight loss benefits, like reducing body weight gain in rats on high-fat diets by inhibiting fat absorption and boosting lipid metabolism (e.g., PMC articles and UMD research). It may aid metabolism via anti-inflammatory effects and
Original Article Human-induced pluripotent stem cell–based hepatic modeling of lipid metabolism–associated TM6SF2-E167K variant Faccioli et al. #LiverX https://t.co/Oft6IqWeKU https://t.co/AYwtZFANY2
Preclinical study: the TCM formula TiaoGanXiaoZhi mitigates MAFLD progression—shifting gut microbiota, improving lipid metabolism, and dampening hepatic inflammation with multi-omics support. Read: https://t.co/xcGrB8ziAj #Hepatology #MAFLD #Microbiome #TCM #LiverTwitter https://t.co/BzcwyLMNz5
with lipids, impairing their ability to clear debris and fueling inflammation. The study, published today, suggests targeting lipid #metabolism could open new #therapeutic avenues.
RT @IsabelRamirezRD: Some of the same elements we discuss in @remissionbiome and work on modulating M116’s microbiome may promote anti-in…
Some of the same elements we discuss in @remissionbiome and work on modulating M116’s microbiome may promote anti-inflammatory responses, short-chain fatty acid production, healthy gut lining, and favorable lipid metabolism cross-talk high Actinobacteriota, driven by https://t.co/ZEmdTqHw3r
Trend up+7: Haykal T, ..., Tohme S (Cancer Res) __Surgery-Induced Neutrophil Extracellular Traps Promote Tumor Metastasis by Reprogramming Cancer Cell Lipid Metabolism__ https://t.co/mbbYRo4vHl
"The multiomics blueprint of the individual with the most extreme lifespan" www.cell.com/cell-reports... @manelesteller.bsky.social & colleagues @carrerasijc.bsky.social @cp-cellrepmed.bsky.social
@CellReports This is an interesting study! Adjusting the sphingolipid-glycerolipid balance to influence caveolin-1 trafficking might have far-reaching implications in cell signaling and membrane biology. How might these findings impact our understanding of lipid metabolism disorders? For
Association of Early Clinical Response to Laser Rejuvenation of Photoaged Skin with Increased Lipid Metabolism and Restoration of Skin Barrier Function https://t.co/NhDUutSl2y
RT @lipo_fan: ❤️"LIPID METABOLISM DISORDER IS A PREREQUISITE FOR THE FORMATION OF ATHEROSCLEROSIS"
RT @jmirpub: New in JMIR mhealth: Impact of a 24-Week #Mobile #App–Based Human Coaching Program on Body Composition and Lipid Metabolism in…
New in JMIR mhealth: Impact of a 24-Week #Mobile #App–Based Human Coaching Program on Body Composition and Lipid Metabolism in Breast #Cancer Survivors With #Overweight or #Obesity: Single-Arm Prospective Cohort Study
New in JMIR mhealth: Impact of a 24-Week #Mobile #App–Based Human Coaching Program on Body Composition and Lipid Metabolism in Breast #Cancer Survivors With #Overweight or #Obesity: Single-Arm Prospective Cohort Study https://t.co/7NLBlUP7qt https://t.co/hmfXFEOjNd
The intricate balance between long-chain saturated fatty acids (SFAs) and polyunsaturated fatty acids (PUFAs) is indeed vital for understanding not just lipid metabolism but also its implications in autoimmune conditions like systemic lupus erythematosus (SLE). https://t.co/bbRkNJf4uK
Conclusion: ➡️ Lipid metabolism plays a central role in pulmonary embolism among severe COVID-19 patients. However, since early metabolic warning signs are subtle, predicting PE in advance remains challenging, and more research is needed to develop clinical applications. 2/2 https://t.co/w01QLdFomy
Indeed, the interplay between long-chain saturated fatty acids (SFAs) and polyunsaturated fatty acids (PUFAs) is complex and crucial for understanding lipid metabolism in tissues. https://t.co/xaZhBCkRCQ
@saffronandsky Effects of dietary alpha- and gamma-linolenic acids on liver fatty acids, lipid metabolism, and survival in sepsis https://t.co/LEtVruEnZC https://t.co/mahE48TdKA "GLA, as a dietary supplement, can help to prevent and treat NAFLD by regulating lipid metabolism and autophagy."
@drabhi619 @theliverdr Many elements align with scientific evidence for liver health: - Bitter greens: Supported for detoxification and reducing inflammation. - Fruits like pomegranate/apples: Pomegranate shows strong benefits; apples generally positive. - Barley: Helps with lipid metabolism and fatty
Chronic cellular stress can alter gut lipid metabolism, increasing long-chain fatty acids that support cancer-promoting bacteria and shift the microbiome toward a state linked to cancer risk. doi.org/g94n27
Rictor stability mediated by USP9X regulates embryo implantation by participating in lipid metabolism of endometrium† https://t.co/RUSabNebbD
Cinnamon Plus™ with Green Coffee and Banaba supports healthy blood sugar metabolism and assists with weight management.* This specialty supplement harnesses the power of 200mg Cinnulin PF™ Cinnamon Extract to support healthy blood pressure and lipid metabolism. Learn more and https://t.co/gGvhHPpUn8
"findings reveal a previously unrecognized role for #mitochondrial #lipid #metabolism in #ALS #pathogenesis & identify a therapeutic pathway for mitigating the #cytotoxic consequences of lipid and acylcarnitine accumulation in FUS-associated #ALS" https://t.co/MtfunJn9Hy
>7M Americans live with Alzheimer’s, and that number could reach 13M by 2050. Cholesterol plays a critical role in brain health, and research suggests there could be a link between lipid metabolism in the brain and Alzheimer’s. Take a closer look at the science: bit.ly/3KhaOty
RT @NEIDirector: Loss of Pnpla2 --a gene crucial for lipid metabolism and retina survival -- accelerates #AMD-like features in mice, unders…
Over 7 million Americans are living with Alzheimer’s disease. By 2050, that number is projected to reach nearly 13 million. Cholesterol plays a critical role in brain health, and research suggests there could be a link between lipid metabolism in the brain and Alzheimer’s. Take https://t.co/48ci7j4Vwh
@geeakinyi_ @amerix Yes, the above advice is not for people with lipid metabolism disorders . My learned friend amerix should put a carvet.
Study from @CQU1929 shows that CSC-derived EVs deliver lncRNA ROLLCSC to LUAD cells by reshaping lipid metabolism & boosting ferroptosis resistance. #OpenAccess: https://t.co/4rO8bZGyGb https://t.co/x4OoUj90HC
Loss of Pnpla2 --a gene crucial for lipid metabolism and retina survival -- accelerates #AMD-like features in mice, underscoring its protective role in retinal health and potential as a therapeutic target. @ARVOtvst paper: https://t.co/p8sGsGZ7nz #NIHfunded @IRPatNIH https://t.co/JS0FkAddTn
@_hairyarse_ It's being claimed eggs with phosphatidylcholine help store Vitamin A in the liver which is disingenuous because PC helps lipid metabolism, improve liver function and improves Vitamin A storage, cholesterol metabolism, bile flow, helps remove fat from the liver, helps
@rust_ruslan This research is quite intriguing and opens new doors in understanding ALS. Targeting lipid droplets may offer fresh therapeutic pathways for reducing neuronal damage in FUS-related ALS cases. I'm curious about the potential side effects of modulating lipid metabolism in neurons
BPA and its alternatives BPF and BPAF exaggerate hepatic lipid metabolism disorders in male mice fed a high fat diet https://t.co/hyb5KhB0PN Science of the Total Environment 867: 161521 2023 ISSN/ISBN: 1879-1026 PMID: 36632902 https://t.co/XZ5qbdgK6c
RT @ARKInvest: Cardiovascular disease is the world’s leading killer. With CRISPR-based therapies targeting lipid metabolism genes, a one-ti…
Mouse PLA2G7 Protein C-His Tag Catalog Number: B2025336 (100 ug) Mouse PLA2G7, is an enzyme involved in lipid metabolism and inflammation. The C-His Tag is a protein tag for purification and detection. https://t.co/6NP1mgSMyu
@TuckerGoodrich The insights shared by @TuckerGoodrich highlight a critical aspect of lipid metabolism and its implications for metabolic health.
@RevereCA2VA @wideawake_media @MohammedAlo Mechanism: Vitamin D plays a role in regulating lipid metabolism and can influence the production of inflammatory markers, which are important in the development of atherosclerosis (plaque buildup in arteries).
The reason why I shill Telmisartan + statin. Is not that your numbers will look good. It’s that they work synergistically. Telmisartan actually enhances lipid metabolism. So when we combine it with cholesterol regulating medication we get 1+1=3
RT @AJPathology: Perilipin 2 Mediates Progression of Lung Adenocarcinoma by Modulating Lipid Metabolism. #OpenAccess text: https://t.co/Jg…
In intestinal organoids, SCD inhibition disrupts lipid metabolism, elevates ER stress, and reduces proliferation, effects rescued by oleic acid. In vivo, Scd1/2 loss may be compensated by dietary lipids, but under nutrient stress or DSS-induced injury, regenerative capacity can become compromised.
John Gordon on Mitochondrial Lipid Metabolism as a Therapeutic Target in Cancer @_AnaBelenAg https://t.co/VTfp6CfYtL #OncoDaily #Oncology #Cancer #Health #Medicine #MedX #MedEd #MedNews @CancerWorldmag https://t.co/hYLVt07cje
"findings reveal a previously unrecognized role for #mitochondrial lipid #metabolism in #ALS pathogenesis & identify a therapeutic pathway for mitigating the #cytotoxic consequences of #lipid & acylcarnitine accumulation in FUS-associated ALS" #LongCovid #ME #PCS https://t.co/9N94tfEiFa
. A healthy lipid metabolism requires - biomonitoring of environmental pollutants, - and adequate sunlight prescriptions. .
RT @JPBY_official: PGC-1α activation boosts exercise-dependent cellular response in the skeletal muscle https://t.co/A5IfLfyU9f @GUMedGda…
RT @JPBY_official: PGC-1α activation boosts exercise-dependent cellular response in the skeletal muscle https://t.co/A5IfLfyU9f @GUMedGda…
PGC-1α activation boosts exercise-dependent cellular response in the skeletal muscle https://t.co/A5IfLfyU9f @GUMedGdansk @Ningbo_Uni @waseda_univ #Skeletal_muscle #PGC_1α_overexpression #Exercise #Mitochondrial_function #Lipid_Metabolism https://t.co/ODCz5JsGKu
Our faculty's newest paper: 'Ginger Extract-Loaded Chitosan Nanoparticles: Investigating their Impact on Lipid Metabolism and Obesity in a Rat Model through In vitro and In vivo Analysis' authored by Gao R.. Available at: https://t.co/UvtbiadVlk
RT @AJPathology: Perilipin 2 Mediates Progression of Lung Adenocarcinoma by Modulating Lipid Metabolism. #OpenAccess text: https://t.co/Jg…
Mazdutide, a Dual GLP-1R/GCGR Agonist, Reduces Hyperuricemia by Modulating Energy and Lipid Metabolism and Inhibiting Hepatic Purine Metabolism https://t.co/tVTBmaVI7u
Perilipin 2 Mediates Progression of Lung Adenocarcinoma by Modulating Lipid Metabolism. #OpenAccess text: https://t.co/Jgp85yyZkf
Perilipin 2 Mediates Progression of Lung Adenocarcinoma by Modulating Lipid Metabolism. #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00202-0/fulltext
GUT MICROBIOME + GLUCOSE METABOLISM A 2025 study on the antidiabetic mechanisms of cinnamon extract found it had positive impacts on intestinal lining integrity & gut microbiota, supporting healthy glucose and lipid metabolism. https://t.co/UBtFGHMcaj https://t.co/XLl4QhWJBX
RT @sahmriAU: On #WorldCMLDay, we've published a review showing that lipid metabolism in leukaemia cells may play a role in CML treatment.…
RT @sahmriAU: On #WorldCMLDay, we've published a review showing that lipid metabolism in leukaemia cells may play a role in CML treatment.…
RT @sahmriAU: On #WorldCMLDay, we've published a review showing that lipid metabolism in leukaemia cells may play a role in CML treatment.…
RT @ASBMB: A recording of our latest #ASBMBBreakthroughs webinar, "Reciprocal regulation between fibrinolysis and lipid metabolism" is now…
Endothelial CEPT1 Regulates Hepatic MTTP-Mediated Lipid Metabolism and Impacts Aortic Atherosclerosis https://www.biorxiv.org/content/10.1101/2025.09.21.677657v1
Endothelial CEPT1 Regulates Hepatic MTTP-Mediated Lipid Metabolism and Impacts Aortic Atherosclerosis https://www.biorxiv.org/content/10.1101/2025.09.21.677657v1
Endothelial CEPT1 Regulates Hepatic MTTP-Mediated Lipid Metabolism and Impacts Aortic Atherosclerosis https://t.co/1ArnOAeqtU #biorxiv_molbio
On World CML Day, we've published a new review showing that lipid metabolism inside leukaemia cells may play a role in CML treatment. Researchers Dr Ilaria Pagani and Molly Tolland say the review offers a fresh perspective on where the next breakthroughs may come from.
5/ Earlier work had hinted that ERAD can target properly folded proteins, mainly regulating lipid metabolism. Our study now links ERAD activity directly to hormone signaling and plant growth control.
On #WorldCMLDay, we've published a review showing that lipid metabolism in leukaemia cells may play a role in CML treatment. Dr Ilaria Pagani and Molly Tolland say the review offers a fresh perspective on where the next breakthroughs may come from.
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RT @ASBMB: A recording of our latest #ASBMBBreakthroughs webinar, "Reciprocal regulation between fibrinolysis and lipid metabolism" is now…
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A recording of our latest #ASBMBBreakthroughs webinar, "Reciprocal regulation between fibrinolysis and lipid metabolism" is now available! ⏯️Watch here: https://t.co/psG6ypvRJY. Ze Zheng of Versiti presented her research on lipid metabolism. #Lipids #LipidMetabolism
Immunometabolic defects of CD8+ T cells disrupt gut barrier integrity in people with #HIV. Lipid metabolism of colon CD8+ T cells is disrupted by PPARγ loss in PWH on ART. PPARγ-deficient colon CD8+ T cells induce epithelial apoptosis. https://t.co/dA4zqQDjjS #AIDS https://t.co/7kHWYjHYwI
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@LyedigCell @MaleehaHashmey Eating early in the evening, such as dinner by 6-7 PM, offers benefits based on studies: - Improves blood glucose control and reduces diabetes risk by lowering nighttime levels. - Boosts lipid metabolism and fat burning after meals. - Decreases hunger and supports weight
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But here’s the hope: If we can fix lipid metabolism or rescue these stem cells… We may finally crack “irreversible” alopecias.
https://t.co/zanwSi0ReK
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Protein kinase A scaffolding by AKAP12 sustains its activation and promotes phosphorylation of its downstream substrates involved in lipid metabolism, thus mitigating #Steatosis & #inflammation in alcohol-associated liver disease. #STTT #OpenAccess: doi.org/10.1038/s413...
This review examines the critical role of lipid metabolism dysregulation in oral cancer development and progression.
UCLA's Dr. Peter Tontonoz wins AHA Basic Research Prize for groundbreaking work in lipid metabolism and cardiovascular science, revealing new insights into heart disease prevention and treatment #Research #Healthcare
Targeting Lipid Metabolism to Enhance Antitumor Immunity Recent advances in oncological research have led to innovative therapeutic strategies aimed at manipulating the body's immune response against tumors. A groundbreaking study by Yang, Zhu, and Yang, as outlined in their publication, presents…
Exploring sex-specific causal links between thousands of proteins and lipid metabolism using the UK Biobank Pharma proteomics data. https://www.medrxiv.org/content/10.1101/2025.09.16.25335948v1
Loss of Nuclear TDP-43 Impairs Lipid Metabolism in Microglia-Like Cells https://www.biorxiv.org/content/10.1101/2025.09.17.676815v1
Loss of Nuclear TDP-43 Impairs Lipid Metabolism in Microglia-Like Cells https://www.biorxiv.org/content/10.1101/2025.09.17.676815v1
TSPO deficiency reveals a novel role for porphyrins in regulating white adipose tissue lipid metabolism https://www.biorxiv.org/content/10.1101/2025.09.14.676078v1
TSPO deficiency reveals a novel role for porphyrins in regulating white adipose tissue lipid metabolism https://www.biorxiv.org/content/10.1101/2025.09.14.676078v1
New Study Explores the Link Between Lipid Metabolism and Parkinson’s Disease Parkinson's Disease (PD), a debilitating neurodegenerative disorder affecting more than 10 million people globally, continues to challenge scientists and clinicians alike due to its complex pathology and lack of curative…
@vinitiwari1.bsky.social and Simons review the relationship between lipid #metabolism & CNS #inflammation and how disruptions in this interplay contribute to neurological disorders. rupress.org/jem/article/...
Mitochondrial lipid metabolism in tumor immunosurveillance and evasion #immunology
Insomnia also reduces insulin sensitivity and negatively affects lipid metabolism. It raises levels of "bad" cholesterol and accelerates the formation of atherosclerotic blades.
Lipid metabolism involved in progression and drug resistance of breast cancer doi.org/10.1016/j.ge...
Immunometabolic defects of CD8+ T cells disrupt gut barrier integrity in people with #HIV. Lipid metabolism of colon CD8+ T cells is disrupted by PPARγ loss in PWH on ART. PPARγ-deficient colon CD8+ T cells induce epithelial apoptosis. www.cell.com/cell/fulltex... #AIDS #MicroSky #IDSky #MedSky
[Nature.com]ABCA7 variants impact phosphatidylcholine and mitochondria in neurons - Nature Loss-of-function variants of ABCA7, associated with Alzheimer’s disease, result in disrupted lipid metabolism, mitochondrial function, DNA repair and synaptic signalling pathways in the human brain.
SOX2 drives esophageal squamous carcinoma by reprogramming lipid metabolism and histone acetylation landscape www.nature.com/articles/s4... After you go through my tutorial github.com/crazyhottom..., you should be able to replicate this figure.
Study explains how a rare gene variant contributes to Alzheimer’s disease news.mit.edu/2025/study-e... Lipid metabolism and cell membrane function can be disrupted in the neurons of people who carry rare variants of ABCA7
Dietary glycerol monolaurate mitigates heat stress-induced disruption of intestinal homeostasis and hepatic lipid metabolism in laying hens Jiang Gao, Hongrui Ren ... Bin He, Wenqiang Ma link.springer.com/article/10.1... #Metabolomic #Transcriptomic #IntestinalBarrier
[Nature.com]ABCA7 variants impact phosphatidylcholine and mitochondria in neurons - Nature Loss-of-function variants of ABCA7, associated with Alzheimer’s disease, result in disrupted lipid metabolism, mitochondrial function, DNA repair and synaptic signalling pathways in the human brain.
Nodal/Smad2 signaling sustains developmental pausing by repressing Pparg-mediated lipid metabolism https://www.biorxiv.org/content/10.1101/2025.09.08.674904v1
Nodal/Smad2 signaling sustains developmental pausing by repressing Pparg-mediated lipid metabolism https://www.biorxiv.org/content/10.1101/2025.09.08.674904v1
Host and microbiome lipid metabolism in colorectal cancer development and therapy
Better late than never. Cancer metabolism: literature from July 2025 (The MetaboList) Amino acids, lipid metabolism, diet and cancer and more... metabolist.wordpress.com/2025/09/02/m...
#SeminarioDeInvestigación
Rare variants of the ABCA7 gene can disrupt lipid metabolism in neurons, increasing Alzheimer's risk; restoring lipid balance with choline may help reverse related cellular dysfunction.
NEW ISSUE! With articles on cancer cachexia, circadian dysruption, lipid metabolism in T cell antitumor activity, brain myelin as an energy source and more! www.cell.com/issue/S1043-...
ER crosstalk in kidney disease: Crucial for Ca²⁺ homeostasis, protein folding, lipid metabolism, and signaling via contact sites. PMID:40745061, Nat Rev Nephrol 2025, @NatRevNeph https://doi.org/10.1038/s41581-025-00989-4 #Medsky #Pharmsky #RNA #ASHG #ESHG
PF-07853578: Leveraging Chemical Biology to Target a Genetically Defined Driver of MASLD | PF-07853578 covalently binds to PNPLA3(I148M), displacing it from lipid droplets and promoting its degradation: a novel strategy to restore lipid metabolism. Read more: drughunter.com/molecule/pf-...
Accumulation of fat within brain immune cells impairs their ability to clear toxic proteins in Alzheimer's, suggesting new therapeutic strategies targeting lipid metabolism in neurodegeneration. doi.org/g923cx
The findings showed that LPEVs reduced body weight, improved aberrant lipid metabolism and inflammation, enhanced intestinal structure, enriched gut flora, influenced metabolite production, and regulated key genes involved in lipid metabolism.
This study investigated the effects of Lactobacillus plantarum extracellular vesicles (LPEVs) on lipid metabolism in mice fed a high-fat diet. Researchers used ultracentrifugation to obtain LPEVs and characterized them.
Importantly, β-hydroxybutyrate also triggered epigenetic changes, opening up chromatin regions associated with lipid metabolism while compacting regions linked to immune function.
“Peroxisomal lipid metabolism inhibits Pimozide-induced cancer cell death by regulating ATP homeostasis”
‘..CSF-specific differentially expressed genes in.. Long COVID, including in genes related to oxidative stress, reactive oxygen species & P53 response, indicating compartment-specific immune responses’ dysregulated pathways ‘..related to androgen response, MTORC1 signaling & lipid metabolism’
Inhibition of autophagy-lysosomal function exacerbates microglial and monocyte lipid metabolism reprograming and dysfunction after brain injury https://www.biorxiv.org/content/10.1101/2025.09.04.674092v1
Inhibition of autophagy-lysosomal function exacerbates microglial and monocyte lipid metabolism reprograming and dysfunction after brain injury https://www.biorxiv.org/content/10.1101/2025.09.04.674092v1
Aging cells struggle to recycle waste. Lysosomes are the cell’s recycling hubs. When they fade, damage builds up. We asked: can lipid metabolism (via PLAG-15) “wake up” lysosome genes and improve cellular housekeeping?
Aging cells struggle to recycle waste. Lysosomes are the cell’s recycling hubs. When they fade, damage builds up. We asked: can lipid metabolism (via PLAG-15) “wake up” lysosome genes and improve cellular housekeeping?
Decoding the Tumor-Suppressive Landscape of SCARA5: A Network-Based Analysis Linking Lipid Metabolism and Immune Regulation in Breast Cancer #SingleCell
Decoding the Tumor-Suppressive Landscape of SCARA5: A Network-Based Analysis Linking Lipid Metabolism and Immune Regulation in Breast Cancer https://www.biorxiv.org/content/10.1101/2025.09.02.672764v1
Decoding the Tumor-Suppressive Landscape of SCARA5: A Network-Based Analysis Linking Lipid Metabolism and Immune Regulation in Breast Cancer https://www.biorxiv.org/content/10.1101/2025.09.02.672764v1
This week selection of articles and #preprints on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/... Highlight: ATF6 activation alters colonic lipid metabolism causing tumour-associated microbial adaptation www.nature.com/articles/s42...
Multi-frequency electromagnetic radiation promoted hepatic lipid metabolism via the adiponectin pathway in mice www.sciencedirect.com/science/arti...
Alterations in ether lipid metabolism in obesity revealed by systems genomics of multi-omics datasets @PLOSBiology.org
Epigenetics Update - SOX2 drives esophageal squamous carcinoma by reprogramming lipid metabolism and histone acetylation landscape go.nature.com/3HP7swZ #Epigenetics #Cancer #HistoneAcetylation #Chromatin --- Gain deeper insights into gene regulation; epigenometech.com
Ophthopedia Update: The role of lipid metabolism disorder in the progression and treatment of ocular vascular diseases: Lipid metabolism plays a critical role in maintaining normal physiological functions and is strongly linked to the pathogenesis of ocular… #Ophthalmology #Eye #Ophthotwitter
Alterations in ether lipid metabolism in obesity revealed by systems genomics of multi-omics datasets @PLOSBiology.org
The findings revealed significant differences in the abundance of proteins involved in carbohydrate metabolism, lipid metabolism, immune response, and complement and coagulation cascades across the infection stages.
Very happy to share our latest publication unravelling how the #ERstress sensor ATF6 stirs up trouble (and tumors) in #colorectalcancer. ATF6 drives CRC by reshaping lipid #metabolism and the intestinal #microbiota. A huge thank you to all co-authors! #lifesciences www.nature.com/articles/s42...
The 13th Xiamen Winter Symposium on Lipid Metabolism and Physiology January 15-18, 2026 Learn more: xws.xmu.edu.cn
Kidney-specific lipid metabolism underlies stable chemical individuality in domestic cats and other felids https://www.biorxiv.org/content/10.1101/2025.09.01.673589v1
Kidney-specific lipid metabolism underlies stable chemical individuality in domestic cats and other felids https://www.biorxiv.org/content/10.1101/2025.09.01.673589v1
Alterations in ether lipid metabolism in obesity revealed by systems genomics of multi-omics datasets @PLOSBiology.org
Save the date for our next #ASBMBBreakthroughs webinar, "Reciprocal regulation between fibrinolysis and lipid metabolism." Details ⬇️ ⬇️ ⬇️ Sept. 17, 2025 | 12:15 p.m. EDT Ze Zheng of @versitiresearch.bsky.social will present her research on lipid metabolism.
SOX2 Rewires Lipid Metabolism in Esophageal Cancer In a groundbreaking study published in Nature Communications, researchers have uncovered a pivotal mechanism by which SOX2, a well-known transcription factor, orchestrates the malignant progression of esophageal squamous cell carcinoma (ESCC). By…
#Lipidomic profiling has linked plasma #EtherLipids with #obesity. This study analyzes a set of biologically informed lipid ratios to reveal obesity-related alterations in enzymatic activity & #GeneticVariants not apparent in traditional lipidomic analyses @plosbiology.org
ATF6 activation alters colonic lipid metabolism causing tumor-associated microbial adaptation @natmetabolism.nature.com www.nature.com/articles/s42...
#Lipidomic profiling has linked plasma #EtherLipids with #obesity. This study analyzes a set of biologically informed lipid ratios to reveal obesity-related alterations in enzymatic activity & #GeneticVariants not apparent in traditional lipidomic analyses @plosbiology.org
Neurovascular Sequelae of SARS-CoV-2: A Comprehensive Analysis of Blood-Brain Barrier Disruption, Microthrombosis, and Cognitive Impairment in Long COVID Study reveals how SARS-CoV-2 hijacks testicular lipid metabolism to replicate. Covid Could Be Quietly Aging Your Arteries by Five Years.
#Lipidomic profiling has linked plasma #EtherLipids with #obesity. This study analyzes a set of biologically informed lipid ratios to reveal obesity-related alterations in enzymatic activity & #GeneticVariants not apparent in traditional lipidomic analyses @plosbiology.org
ATF6 activation alters colonic lipid metabolism causing tumour-associated microbial adaptation ->Nature | More info from EcoSearch
ATF6 Activation Shifts Colon Lipids, Drives Microbial Change In a groundbreaking study poised to reshape our understanding of tumor biology and microbiome interactions, researchers have unearthed the intricate ways in which activation of the transcription factor ATF6 alters lipid metabolism in the…
#MicroSky: Yarrowia is a rising star in synthetic biology — GRAS, strong lipid metabolism & efficient secretion. But, there are Bottlenecks: weak dynamic promoters + low-efficiency gene editing. Li &Qi in MBT doi.org/10.1111/1751... provide Solutions: ML-driven regulatory modules & orthogonal CRISPR
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