Cellular reprogramming and epigenetic rejuvenation.

Daniel J Simpson, Nelly N Olova, Tamir Chandra

September 2021

Synopsis of Social media discussions

The interactions show a recognition of the scientific significance of cellular reprogramming, with posts urging debates among prominent scientists and mentioning research such as epigenetic age reversal and Yamanaka factors. The tone and choice of words like 'refute,' 'urge debate,' and references to specific methods reflect both curiosity and cautious optimism about the potential impact of this research.

A
Agreement
 Moderate agreement

Most discussions acknowledge the potential of cellular reprogramming and epigenetic rejuvenation, with some asserting its relevance to longevity and future scientific advances.

I
Interest
 Moderate level of interest

Posts demonstrate moderate interest, sharing articles, calling for debates, and discussing scientific concepts without deeply engaging in technical details.

E
Engagement
 Moderate level of engagement

Multiple discussions reference specific scientific methods, like Yamanaka factors, and call for debates or further conversations, indicating a reasonable level of engagement.

I
Impact
 Moderate level of impact

Though some posts highlight significant potential impacts, such as reversing aging or rejuvenating tissues, many are speculative or calling for debates, so overall impact is viewed as promising but not yet conclusive.

Social Mentions

YouTube

19 Videos

Facebook

2 Posts

Twitter

97 Posts

Blogs

5 Articles

News

5 Articles

Reddit

3 Posts

Metrics

Video Views

46,986

Total Likes

1,629

Extended Reach

382,731

Social Features

131

Timeline: Posts about article

Top Social Media Posts

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  • GilbertiusIV
    @IvArends (Twitter)

    RT @003Energenic: Do you agree that the loss of fast motor units is fatal to longevity? https://t.co/wSoh2j62WY @aubreydegrey @siimland @…
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    January 8, 2025

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  • 003
    @003Energenic (Twitter)

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    January 8, 2025

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  • arctic monkeey
    @MonkeeyArctic (Twitter)

    RT @MarcosArrut: I recommend this article if you want to understand more about the logic of cellular reprogramming and aging: “https://t.co…
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    October 25, 2024

    2

  • Anthony M. Hopper
    @elander777 (Twitter)

    RT @MarcosArrut: I recommend this article if you want to understand more about the logic of cellular reprogramming and aging: “https://t.co…
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    October 24, 2024

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  • Marcos Arrut
    @MarcosArrut (Twitter)

    I recommend this article if you want to understand more about the logic of cellular reprogramming and aging: “https://t.co/0huWUDVcJN”. That's all. (actually there are more articles)
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    October 24, 2024

    29

    2

  • Marcos Arrut
    @MarcosArrut (Twitter)

    @YLX2050 Perfect, thank you for your response. Regarding scientific advances, there are a variety of scientific articles that may be of interest to you. I recommend this one: https://t.co/0huWUDVcJN Regarding the philosophical question, the books defending transhumanism may be useful to
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    October 24, 2024

    1

  • Lyn Myers
    @LynMyer28562546 (Twitter)

    "Cellular reprogramming and epigenetic rejuvenation | Clinical Epigenetics | Full Text" https://t.co/EFEghzrff9
    view full post

    May 8, 2024

    1

  • Lyn Myers
    @LynMyer28562546 (Twitter)

    "cellular reprogramming and epigenetic rejuvenation - Google Scholar" https://t.co/4qBSTuPNvz
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    May 8, 2024

    1

  • Marcos Arrut
    @MarcosArrut (Twitter)

    @reznavajo No evidence? All yours, sir: https://t.co/4G4eWboANI https://t.co/SVSUZdn67b https://t.co/zLoiuTilNN https://t.co/eeNg8ypjoW https://t.co/DlGd08J2I2 Treating my scientific colleagues as corrupt is a strong offense to the field.
    view full post

    April 7, 2024

    1

  • Jim Rice
    @JimRice1111 (Twitter)

    @statto I mean, that’s what epigenetic reprogramming with Yamanaka factors is. And this can indeed rejuvenate and repair tissue. Not sure what you’re saying here. https://t.co/xj2f8c1a53
    view full post

    August 18, 2023

  • luis hernan graffe
    @hernangraffe (Twitter)

    RT @hernangraffe: https://t.co/pEfLYLZ53N
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    August 13, 2023

    1

  • luis hernan graffe
    @hernangraffe (Twitter)

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    August 13, 2023

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  • ∤∤∤∤∤
    @punishdtriangls (Twitter)

    Cellular reprogramming and epigenetic rejuvenation https://t.co/SI1AiUuiKG
    view full post

    June 25, 2023

    2

  • Siomy Coxese
    @mujaya_ (Twitter)

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    view full post

    May 19, 2023

  • 西澤三橋NishizawaMihashi
    @TakashiMichaels (Twitter)

    RT @NameIsSpartacus: @carl_jurassic @GrantCardone This is what they're after: https://t.co/MtXMVpa2O6 https://t.co/3uBLoHcPyO https://t.…
    view full post

    April 10, 2023

    2

  • R.A
    @raan62 (Twitter)

    RT @agingdoc1: Cellular reprogramming and epigenetic rejuvenation https://t.co/ITAaYwmbll
    view full post

    March 21, 2023

    1

  • One Health Genomics Edinburgh
    @GenomicsEdi (Twitter)

    New paper: Cellular reprogramming and epigenetic rejuvenation @mrc_hgu @EdinUni_IGC https://t.co/dVDs2ZmIx1 https://t.co/rIcrRuQxlj
    view full post

    March 3, 2023

  • Jurassic Carl
    @carl_jurassic (Twitter)

    RT @NameIsSpartacus: @carl_jurassic @GrantCardone This is what they're after: https://t.co/MtXMVpa2O6 https://t.co/3uBLoHcPyO https://t.…
    view full post

    February 7, 2023

    2

  • WeAreIceni
    @NameIsSpartacus (Twitter)

    @carl_jurassic @GrantCardone This is what they're after: https://t.co/MtXMVpa2O6 https://t.co/3uBLoHcPyO https://t.co/KHQAM99dkd https://t.co/PMG5WfmMv3 Using Yamanaka Factors to reset the epigenome without going too far and turning the patient into a blob of fresh induced pluripotent stem cells.
    view full post

    February 7, 2023

    4

    2

  • bladerunner
    @bladerunner3049 (Twitter)

    https://t.co/MhWHpncNuF
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    @LongevityTao (Twitter)

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    January 2, 2023

  • BreakthroughMedicine&AdvancedResearchTools
    @JayChance12 (Twitter)

    @NIHDirector @doudna_lab @UCBerkeley @SFNeurologie @CHU_Grenoble @HopPitieSalpe @biorxiv_neursci @NeuroscienceNew @ImagingOrg @Nanowerk @NatureNeuro @InstitutCerveau @mitbrainandcog @Cognition_ENS @Eduscol @EPFL @Inria @Inserm @GoogleAI @IBM ⬆️From https://t.co/DjR7pyH4cY https://t.co/aum3D5TOiy 2019Preprint #DNA #epigenetics https://t.co/7h8assUYP4 #Telomere BasicComprehensive ➡️https://t.co/hpUpo9eQ6r https://t.co/wo1NJ5TE0h https://t.co/HtaWvTlgRW https://t.co/2UyEIxqy3J 2021 ➡️https://t.co/CM1LGrK6Dc .
    view full post

    December 13, 2022

  • Madam Mitochondria
    @Madam_Mito (Twitter)

    @traceflow_ @KiesowPaul @yeeseak https://t.co/tbMpQHwvpo
    view full post

    November 24, 2022

  • Alison Wright
    @alisonmwright45 (Twitter)

    "(T)he ageing process may not be as inevitable as previously thought. Young blood has been shown to have rejuvenative properties through heterochronic parabiosis, whereby the circulatory systems of a young and old organism are connected." https://t.co/wnugJE1fdr
    view full post

    September 10, 2022

  • Alison Wright
    @alisonmwright45 (Twitter)

    RT @alisonmwright45: @enemy2me "Young blood has been shown to have rejuvenative properties through heterochronic parabiosis, whereby the ci…
    view full post

    September 10, 2022

    1

  • Alison Wright
    @alisonmwright45 (Twitter)

    @enemy2me "Young blood has been shown to have rejuvenative properties through heterochronic parabiosis, whereby the circulatory systems of a young and old organism are connected". Think about what a group of psychopaths might have been doing with this knowledge. https://t.co/wnugJE1fdr
    view full post

    September 10, 2022

    2

    1

  • Biotechnomuffin | Divulgación
    @biotechnomuffin (Twitter)

    FUENTES: Cell Reprogramming: The Many Roads to Success ➡️ https://t.co/p7LOluglKo Somatic Cell Nuclear Transfer Reprogramming: Mechanisms and Applications ➡️ https://t.co/uzrFCLtW5D Cellular reprogramming and epigenetic rejuvenation ➡️ https://t.co/VZxdhk0N08
    view full post

    August 27, 2022

    1

  • luis hernan graffe
    @hernangraffe (Twitter)

    RT @hernangraffe: https://t.co/pEfLYLZ53N
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    August 5, 2022

    1

  • luis hernan graffe
    @hernangraffe (Twitter)

    https://t.co/pEfLYLZ53N
    view full post

    August 5, 2022

    1

  • Raghav Agrawal
    @impactology (Twitter)

    [open access] Cellular reprogramming and epigenetic rejuvenation by Daniel J. Simpson, Nelly N. Olova & Tamir Chandra https://t.co/XW61ZgOvVk https://t.co/u28nzFXEwf
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    July 7, 2022

  • Brushed Alloy
    @BrushedAlloy (Twitter)

    Review: Cellular reprogramming and epigenetic rejuvenation. https://t.co/QpO78EbYrV
    view full post

    May 5, 2022

  • Nelly Olova
    @NeliOlova (Twitter)

    @GeneInvesting @adanguyenx It has already been shown in 2018 that in a reprogramming time course (in a dish yes) epigenetic age of skin cells drops with ~30 years in the first two weeks. This method has been used by many by now, a summary can be found here: https://t.co/ewlZn6DfWN
    view full post

    April 11, 2022

  • Xapiens at MIT
    @XapiensMIT (Twitter)

    Cellular reprogramming and epigenetic rejuvenation https://t.co/sznkXbh50p https://t.co/afgm9Z8oSo
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    March 21, 2022

  • Genetics at BMC
    @OAgenetics (Twitter)

    Clinical Epigenetics: Check out what your peers read. Highly viewed articles from 2021: https://t.co/wXaLAvint5, https://t.co/sCMLPiMft8, https://t.co/PsAjTG73Ss https://t.co/9enUSK8yNz
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    February 14, 2022

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  • J Fuller
    @jordan_emmitt (Twitter)

    RT @jnearestn: @KKajderowicz @ArtirKel @realNathanCheng @adanguyenx @michellebkwok @gottapatchemall @AlexandreTrapp I'll list the obvious b…
    view full post

    December 24, 2021

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  • jared tumiel
    @jnearestn (Twitter)

    @KKajderowicz @ArtirKel @realNathanCheng @adanguyenx @michellebkwok @gottapatchemall @AlexandreTrapp I'll list the obvious but this was a great start https://t.co/7rbd91A8r2
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    December 19, 2021

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  • Cecile Tamura
    @ceciletamura (Twitter)

    https://t.co/sCSln7Cr9g
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    December 17, 2021

    1

  • Cecile Tamura
    @ceciletamura (Twitter)

    Cellular reprogramming and epigenetic rejuvenation https://t.co/2CqHOwfD41
    view full post

    December 17, 2021

  • Patriot Boy Von Milky Way
    @HelgerOun (Twitter)

    RT @ydeigin: Fresh paper from Olova — the author of my favorite graph tracking epigenetic age reversal during reprogramming — and coauthors…
    view full post

    October 17, 2021

    4

  • Liz Rose
    @LizRose14449371 (Twitter)

    RT @ydeigin: Fresh paper from Olova — the author of my favorite graph tracking epigenetic age reversal during reprogramming — and coauthors…
    view full post

    October 16, 2021

    4

  • Healthspan
    @HealthspanBot (Twitter)

    #FightAging #EndAging #Lifespan #Healthspan https://t.co/602ZDqb53h
    view full post

    October 9, 2021

    1

  • Liz Rose
    @LizRose14449371 (Twitter)

    RT @dives86: A great summary of Reprogramming Induced Rejuvenation (RIR) studies https://t.co/5nfjLqf7do
    view full post

    September 21, 2021

    1

  • Daniel Ives
    @dives86 (Twitter)

    A great summary of Reprogramming Induced Rejuvenation (RIR) studies https://t.co/5nfjLqf7do
    view full post

    September 21, 2021

    11

    1

  • Travis Statham
    @Travis_Statham (Twitter)

    I just posted "Cellular reprogramming and epigenetic rejuvenation -- Various diets (e.g. calorie restriction, IF, ketogenic diet) manipulate nutrient sensing pathways, particularly those involving mTOR and insulin/i..." on Reddit https://t.co/tTsIAwCFuM
    view full post

    September 16, 2021

  • Mogrify
    @Mogrify_UK (Twitter)

    Recent research has shown that OKSM #transcriptionfactors can induce #epigenetic #rejuvenation via particle #cellreprogramming, a potential strategy against #aging. Read more in the latest review from @mrc_hgu. @BioMedCentral #ClinicalEpigenetics https://t.co/IpiNxDg8q1 https://t.co/UCHFxAePJ3
    view full post

    September 14, 2021

  • Michael Buratovich
    @MichaelBuratovi (Twitter)

    RT @ESC_iPSC_News: A team of @EdinUni_IGC investigators at @EdinburghUni reviewed the development and potential of #reprogramming-induced r…
    view full post

    September 11, 2021

    4

  • Antonei B Csoka, PhD
    @abcsoka (Twitter)

    RT @ESC_iPSC_News: A team of @EdinUni_IGC investigators at @EdinburghUni reviewed the development and potential of #reprogramming-induced r…
    view full post

    September 11, 2021

    4

  • Ahmed Morsy
    @morsyfuture (Twitter)

    RT @ESC_iPSC_News: A team of @EdinUni_IGC investigators at @EdinburghUni reviewed the development and potential of #reprogramming-induced r…
    view full post

    September 10, 2021

    4

  • maria marquez
    @lormarmar (Twitter)

    RT @ESC_iPSC_News: A team of @EdinUni_IGC investigators at @EdinburghUni reviewed the development and potential of #reprogramming-induced r…
    view full post

    September 10, 2021

    4

  • ESC & iPSC News
    @ESC_iPSC_News (Twitter)

    A team of @EdinUni_IGC investigators at @EdinburghUni reviewed the development and potential of #reprogramming-induced rejuvenation as an anti-aging strategy.
    view full post

    September 10, 2021

    10

    4

  • Nelly Olova
    @NeliOlova (Twitter)

    RT @RuggGunnLab: "Cellular reprogramming and epigenetic rejuvenation" by @BiologyAgeing, @DanielJSimpson4, @NeliOlova. Congratulations to t…
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    September 9, 2021

    2

  • Angel David
    @AngelDavid_96 (Twitter)

    RT @RuggGunnLab: "Cellular reprogramming and epigenetic rejuvenation" by @BiologyAgeing, @DanielJSimpson4, @NeliOlova. Congratulations to t…
    view full post

    September 9, 2021

    2

  • Rugg-Gunn Lab
    @RuggGunnLab (Twitter)

    "Cellular reprogramming and epigenetic rejuvenation" by @BiologyAgeing, @DanielJSimpson4, @NeliOlova. Congratulations to the authors! This is the third article in the series "Regenerative Medicine and Epigenetics". https://t.co/Zfw0cSrGy4
    view full post

    September 9, 2021

    6

    2

  • Nelly Olova
    @NeliOlova (Twitter)

    RT @OAgenetics: Proud to publish the latest in Clinical Epigenetics' series on "Regenerative Medicine and Epigenetics", a review on cellula…
    view full post

    September 7, 2021

    2

  • Daniel J. Simpson
    @DanielJSimpson4 (Twitter)

    RT @OAgenetics: Proud to publish the latest in Clinical Epigenetics' series on "Regenerative Medicine and Epigenetics", a review on cellula…
    view full post

    September 7, 2021

    2

  • Genetics at BMC
    @OAgenetics (Twitter)

    Proud to publish the latest in Clinical Epigenetics' series on "Regenerative Medicine and Epigenetics", a review on cellular reprogramming & epigenetic rejuvenation by @DanielJSimpson4, @NeliOlova, @BiologyAgeing @EdinburghUni @mrc_hgu https://t.co/sCMLPiMft8
    view full post

    September 7, 2021

    2

    2

  • Agingdoc
    @agingdoc1 (Twitter)

    Cellular reprogramming and epigenetic rejuvenation https://t.co/ITAaYwmbll
    view full post

    September 7, 2021

    6

    1

  • hoeman
    @_hoeman (Twitter)

    RT @ydeigin: Fresh paper from Olova — the author of my favorite graph tracking epigenetic age reversal during reprogramming — and coauthors…
    view full post

    September 7, 2021

    4

  • alex
    @alexsisu (Twitter)

    RT @ydeigin: Fresh paper from Olova — the author of my favorite graph tracking epigenetic age reversal during reprogramming — and coauthors…
    view full post

    September 7, 2021

    4


  • @0xGEONEO (Twitter)

    RT @ydeigin: Fresh paper from Olova — the author of my favorite graph tracking epigenetic age reversal during reprogramming — and coauthors…
    view full post

    September 7, 2021

    4

  • Yuri Deigin
    @ydeigin (Twitter)

    Fresh paper from Olova — the author of my favorite graph tracking epigenetic age reversal during reprogramming — and coauthors: https://t.co/ds5vasuEkL
    view full post

    September 7, 2021

    8

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Abstract Synopsis

  • Cellular reprogramming, like creating induced pluripotent stem cells, shows potential to slow down or reverse aging but typically involves losing the original cell identity.
  • Epigenetic rejuvenation aims to separate the beneficial rejuvenating effects of reprogramming from complete cell dedifferentiation, making it a safer anti-aging strategy.
  • Reprogramming-induced rejuvenation using Yamanaka factors is a promising approach to reducing biological age without fully reverting cells to a pluripotent state.]