February 2022 PMID 34532853

The role of glucagon-like peptide 1 (GLP-1) in addictive disorders.

Mette Kruse Klausen, Morgane Thomsen, Gitta Wortwein, Anders Fink-Jensen

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Mentions

166
Peak: 9 in May 2023
across 6 sources since Jan 2021

Extended reach

862,190
potential audience

Total likes

354

Video views

4,133

Mentions per month

Jan 2021 – Oct 2025

Where it's discussed

  • News119 articles
  • X / Twitter29 posts
  • Blogs12 articles
  • Bluesky2 posts
  • YouTube2 videos
  • Facebook2 posts

AI synopsis

What people are saying

The discussions reveal a keen interest in the emerging research on GLP-1’s role in addiction, with posts citing recent publications, mechanisms involving dopamine pathways, and the therapeutic promise of medications like Ozempic. The tone varies from enthusiastic praise—calling it 'psychiatry’s secret weapon'—to more cautious notes about mechanisms still being investigated, illustrating a mix of optimism and critical curiosity that enriches the overall conversation.

AgreementModerate agreement

Most discussions acknowledge the promising role of GLP-1 in addiction treatment, with several posts referencing research evidence and therapeutic potential.

InterestHigh interest

The posts demonstrate high curiosity, referencing new research, mechanisms, potential applications, and even celebrity influence, indicating strong engagement with the topic.

EngagementHigh engagement

Many discussions go beyond superficial mentions, including mentions of mechanisms, clinical trials, and calls for further exploration, reflecting deep engagement.

ImpactModerate impact

Posts generally see GLP-1 research as impactful, discussing its potential to revolutionize addiction and mental health treatment, though some skepticism remains.

Abstract in brief

  • Glucagonlike peptide 1 (GLP1) plays a potential role in treating addiction, including alcohol and tobacco use disorders, by reducing drug intake and craving.
  • Research in animals and early clinical trials suggest that GLP1 receptor agonists, which are already used for diabetes and obesity, might help decrease substance use possibly by affecting dopamine pathways in the brain.
  • While promising, the exact mechanisms of how GLP1 influences addictive behaviors are still being studied, but it is believed to involve central nervous system effects related to dopamine signaling.]

Top posts

Most liked on X and Bluesky
Prof Francois Balloux
@BallouxFrancois · X

@VPrasadMDMPH I agree this is plausible. There are obvious parallels between overeating and addictions to alcohol and drugs. GLP-1R agonists have been suggested to have a broad effect on reducing addictive behaviours (eg. below). https://t.co/m23DBtBftJ

May 20, 2023 · 33 likes · 2 shares · 143,357 followers View post →
C. Michael Gibson MD
@CMichaelGibson · X

The role of glucagon‐like peptide 1 (GLP‐1) in addictive disorders https://t.co/3bFOqGmeLn

Oct 13, 2022 · 16 likes · 6 shares · 431,990 followers View post →
KSalberta @k_salberta@masto.ai @ksalberta.bsky.soc
@k_salberta · X

@vijaypande There's solid evidence that GLP-1 inhibitors do affect addictive behaviors. Here's a paper: https://t.co/NIhdu50hkk

May 19, 2023 · 12 likes · 2 shares · 984 followers View post →
Frontiers - Neuroscience
@FrontNeurosci · X

New Research: Can GLP-1 Be a Target for Reward System Related Disorders? A Qualitative Synthesis and Systematic Review Analysis of Studies on Palatable Food, Drugs of Abuse, and Alcohol: The role of glucagon-like peptide 1 (GLP-1) in… https://t.co/6s1EXay1Wx #neuroscience

Jan 30, 2021 · 4 likes · 4 shares · 80,922 followers View post →
Sulman Aziz Mirza, MD? | TheKicksShrink
@sulmoney · X

@yash_adroja @thehouseofpod @DrNadolsky @DrKarlNadolsky came here to say this i could also talk about it from the psych point of view where we have seen amazing results and different utilizations

May 25, 2024 · 4 likes · 7,341 followers View post →
Sulman Aziz Mirza, MD? | TheKicksShrink
@sulmoney · X

@therealRYC @nplusyears @JAMAPsych Made a video on the topic a bit ago (need to make a new thumbnail haha) Long and short, no need to adjust dosing either. Work them independently. Can My Psychiatrist Prescribe Ozempic? | Ozempic And Mental Health https://t.co/6jqEe8L8UP

Sep 5, 2025 · 2 likes · 7,341 followers View post →

All mentions

Sulman Aziz Mirza, MD? | TheKicksShrink
@sulmoney · X

@therealRYC @nplusyears @JAMAPsych Made a video on the topic a bit ago (need to make a new thumbnail haha) Long and short, no need to adjust dosing either. Work them independently. Can My Psychiatrist Prescribe Ozempic? | Ozempic And Mental Health https://t.co/6jqEe8L8UP

Sep 5, 2025 · 2 likes · 7,341 followers View post →
Obstetrics & Gynecology (the Green Journal)
@greenjrnl.bsky.social · Bluesky

What you need to know on the "Role of Glucagon-Like Peptide-1 Receptor Agonists in People With Infertility and Pregnancy" -- read now at ow.ly/Ywno50V9FhU

Mar 4, 2025 View post →
Jim Myers
@kidneystories.bsky.social · Bluesky

An analysis on the role of glucagon-like peptide-1 receptor agonists in cognitive and mental .. - goo.gl/alerts/qmw8HR #GoogleAlerts

Feb 13, 2025 View post →
Queen
@_forever_queen · X

RT @dextrodexter: @vijaypande That been said, there’s more to investigated about the mechanism. I posit this interaction occurs at the casc…

Jun 27, 2024 · 1 share · 3,991 followers View post →
Sulman Aziz Mirza, MD? | TheKicksShrink
@sulmoney · X

@yash_adroja @thehouseofpod @DrNadolsky @DrKarlNadolsky came here to say this i could also talk about it from the psych point of view where we have seen amazing results and different utilizations

May 25, 2024 · 4 likes · 7,341 followers View post →
Hope never surrenders
@Fear_Not_Ever · X

Tons of negative attention on Ozempic, while silent on the other 7 FDA approved weight loss medications. Is it the fact GLP-1s like Ozempic are being studied as potential drug & alcohol anti-addiction treatments or the fact celebrities are misusing them. https://t.co/74ac0yWZ8k https://t.co/4VDjLZ4ga1

Feb 3, 2024 · 800 followers View post →
Sulman Aziz Mirza, MD? | TheKicksShrink
@sulmoney · X

@RecoveryDoctor @rogersmcintyre Yeah my initial version of the tweet was medicine instead of psychiatry. I call it the biggest advancement in medicine since Viagra in my video I did on it a little while ago. Why Ozempic Is Psychiatry's SECRET Weapon! https://t.co/6jqEe8L8UP

Jan 2, 2024 · 1 like · 7,341 followers View post →
Sulman Aziz Mirza, MD? | TheKicksShrink
@sulmoney · X

https://t.co/zfyWSoqXaU

Nov 9, 2023 · 7,341 followers View post →
Gustavo Bras
@GustavoBras · X

@l_oshman @MWeintraubMD https://t.co/Kw4UucftEm

Jul 22, 2023 · 301 followers View post →
Mehmet Akif
@mehmett_aakif · X

@chagataikhante @oozn GLP-1'in alkol ve madde kullanım bozukluklarındaki etkilerine merkezi olarak, en azından kısmen dopamin sinyali yoluyla aracılık edildiğini, ancak kesin mekanizmaların hala ortaya çıkarılmadığını öne sürüyoruz. https://t.co/xpTDzTkDa5

May 28, 2023 · 8 followers View post →
Hillary Lin, MD
@HillaryLinMD · X

Ozempic, Wegovy, Mounjaro - GLP-1 Agonists for Addiction? This is just hitting the mainstream headlines now, but there has been research on non-human models on substance abuse disorders and the role of GLP-1 in reducing addiction for years now. https://t.co/GRo3aCGhIX

May 22, 2023 · 1 like · 590 followers View post →
…
@dextrodexter · X

@vijaypande That been said, there’s more to investigated about the mechanism. I posit this interaction occurs at the cascading level because both GLP-1 and dopamine patronize cyclic AMP and it’s associates. More info here in this publication

May 21, 2023 · 1 share · 1,543 followers View post →
Rich Law
@drrichjlaw · X

RT @k_salberta: @vijaypande There's solid evidence that GLP-1 inhibitors do affect addictive behaviors. Here's a paper: https://t.co/NIhdu5…

May 20, 2023 · 2 shares · 4,180 followers View post →
showmethescience
@friiedaaaaaa · X

RT @BallouxFrancois: @VPrasadMDMPH I agree this is plausible. There are obvious parallels between overeating and addictions to alcohol and…

May 20, 2023 · 2 shares · 208 followers View post →
Progressive_Einsteinia
@Prog4_1st_Amend · X

RT @k_salberta: @vijaypande There's solid evidence that GLP-1 inhibitors do affect addictive behaviors. Here's a paper: https://t.co/NIhdu5…

May 20, 2023 · 2 shares · 734 followers View post →
Agnes Wold
@AgnesWold · X

RT @BallouxFrancois: @VPrasadMDMPH I agree this is plausible. There are obvious parallels between overeating and addictions to alcohol and…

May 20, 2023 · 2 shares · 113,275 followers View post →
Prof Francois Balloux
@BallouxFrancois · X

@VPrasadMDMPH I agree this is plausible. There are obvious parallels between overeating and addictions to alcohol and drugs. GLP-1R agonists have been suggested to have a broad effect on reducing addictive behaviours (eg. below). https://t.co/m23DBtBftJ

May 20, 2023 · 33 likes · 2 shares · 143,357 followers View post →
KSalberta @k_salberta@masto.ai @ksalberta.bsky.soc
@k_salberta · X

@vijaypande There's solid evidence that GLP-1 inhibitors do affect addictive behaviors. Here's a paper: https://t.co/NIhdu50hkk

May 19, 2023 · 12 likes · 2 shares · 984 followers View post →
Linda
@wordfinga · X

RT @CMichaelGibson: The role of glucagon‐like peptide 1 (GLP‐1) in addictive disorders https://t.co/3bFOqGmeLn

Dec 14, 2022 · 6 shares · 4,587 followers View post →
Cristal Palacios Yumar
@CristalPalacios · X

@hubermanlab Hi! I'd love your take on this. Perhaps a deep-dive podcast? So interesting and so much potential! https://t.co/t6CsgBLjCq.

Nov 17, 2022 · 6,648 followers View post →
Gufran
@Gufransir · X

RT @CMichaelGibson: The role of glucagon‐like peptide 1 (GLP‐1) in addictive disorders https://t.co/3bFOqGmeLn

Oct 14, 2022 · 6 shares · 813 followers View post →
Donna LeNarz, RN, BSN
@donna_lenarz · X

RT @CMichaelGibson: The role of glucagon‐like peptide 1 (GLP‐1) in addictive disorders https://t.co/3bFOqGmeLn

Oct 13, 2022 · 6 shares · 1,103 followers View post →
Karthik Balachandran
@karthik2k2 · X

RT @CMichaelGibson: The role of glucagon‐like peptide 1 (GLP‐1) in addictive disorders https://t.co/3bFOqGmeLn

Oct 13, 2022 · 6 shares · 21,955 followers View post →
Aesculapius1898
@Aesculapius1898 · X

RT @CMichaelGibson: The role of glucagon‐like peptide 1 (GLP‐1) in addictive disorders https://t.co/3bFOqGmeLn

Oct 13, 2022 · 6 shares · 538 followers View post →
C. Michael Gibson MD
@CMichaelGibson · X

The role of glucagon‐like peptide 1 (GLP‐1) in addictive disorders https://t.co/3bFOqGmeLn

Oct 13, 2022 · 16 likes · 6 shares · 431,990 followers View post →
MyJournals
@myjournals · X

The role of glucagon‐like peptide 1 (GLP‐1) in addictive disorders https://t.co/IpNAFDB0ha

Sep 17, 2021 · 557 followers View post →
COLLINS MALLACS
@CMallacs · X

RT @FrontNeurosci: New Research: Can GLP-1 Be a Target for Reward System Related Disorders? A Qualitative Synthesis and Systematic Review A…

Feb 1, 2021 · 4 shares · 171 followers View post →
Ariakas Enoreth
@Aenoreth · X

RT @FrontNeurosci: New Research: Can GLP-1 Be a Target for Reward System Related Disorders? A Qualitative Synthesis and Systematic Review A…

Jan 31, 2021 · 4 shares · 1,004 followers View post →
AbizaidAlfie
@AbizaidAlfie · X

RT @FrontNeurosci: New Research: Can GLP-1 Be a Target for Reward System Related Disorders? A Qualitative Synthesis and Systematic Review A…

Jan 31, 2021 · 4 shares · 1,585 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @FrontNeurosci: New Research: Can GLP-1 Be a Target for Reward System Related Disorders? A Qualitative Synthesis and Systematic Review A…

Jan 30, 2021 · 4 shares · 6,710 followers View post →
Frontiers - Neuroscience
@FrontNeurosci · X

New Research: Can GLP-1 Be a Target for Reward System Related Disorders? A Qualitative Synthesis and Systematic Review Analysis of Studies on Palatable Food, Drugs of Abuse, and Alcohol: The role of glucagon-like peptide 1 (GLP-1) in… https://t.co/6s1EXay1Wx #neuroscience

Jan 30, 2021 · 4 likes · 4 shares · 80,922 followers View post →