The genetics of obesity: from discovery to biology https://t.co/Fi7W9lE78Q #Review by Ruth J. F. Loos & @gilesyeo @Metabolcenter @IcahnMountSinai @MRL_Cam Free to read here: https://t.co/pvK6Ea8wpS
The genetics of obesity: from discovery to biology.
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Sep 2021 – Aug 2025Where it's discussed
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X / Twitter101 posts
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What people are saying
Several posts highlight the publication's relevance, such as one referencing the significant insights into genetic contributions to body mass index (BMI) and another emphasizing the complexity of obesity discussed in the article. The use of terms like 'revolutionary' and 'must-read' indicates excitement and urgency, reinforcing the importance of the publication in shaping future discussions and strategies in obesity research.
A majority of the posts express support for the publication's insights, indicating a shared understanding of obesity's genetic basis.
The participants demonstrate a high level of curiosity, with many references to further readings and studies related to obesity genetics.
While several posts reference the article, the depth of discussion varies, with some users engaging more thoroughly by sharing additional studies.
Overall, contributors perceive the research as having significant implications for the treatment and understanding of obesity.
Abstract in brief
- The prevalence of obesity has surged in the last 40 years, presenting significant health challenges and distinguishing between common polygenic obesity and rare monogenic obesity.
- Recent gene discovery studies reveal shared genetic and biological characteristics in both types of obesity, highlighting the brain's crucial role in weight control.
- Advances in genome-wide association studies (GWAS) and collaborative research across disciplines are enhancing our understanding of obesity genetics and paving the way for new treatment strategies.
Top posts
Most liked on X and BlueskyThe genetics of obesity: from discovery to biology | Nature Reviews Genetics https://t.co/gHboJGyk1R by @GilesYeo & Ruth Loos - #openaccess
The genetics of obesity: from discovery to biology https://t.co/cwJbhFKapr https://t.co/ovsAF79Qso
@MiriamBerchuk @MichelleCardel @EmilyDhurandhar @sguyenet The two best reviews on this topic: [1] Variability in the Heritability of Body Mass Index: A Systematic Review and Meta-Regression https://t.co/gRT3xvXlrD [2] The genetics of obesity: from discovery to biology https://t.co/HD8gHEroeu
A review so nice @NatureRevGenet tweeted it twice!
The genetics of obesity: from discovery to biology go.nature.com/4h5x9os #WorldObesityDay Free to read here: rdcu.be/eb3bF
All mentions
Understanding Monogenic and Polygenic Obesity
This video explores the genetics of obesity, distinguishing between common polygenic and rare monogenic forms. It discusses the role of genetics and recent advancements in treatment strategies, emphasizing the…
Understanding Obesity: Choices vs. Genetic Influences
The debate around obesity encompasses complex factors beyond mere choice. While 35% of obesity cases are purely genetic, many are influenced by behavioral and environmental aspects. This video explores how genetics…
One notable paper on this topic is "The genetics of obesity: from discovery to biology" available at https://www.nature.com/articles/s41576-021-00414-z which discusses how recent gene studies are transforming our understanding of obesity's biological mechanisms.
Ser gordo é escolha, disseram... https://t.co/TmnqGxsFFW via @YouTube
Ser gordo é escolha, disseram... https://t.co/9lZ0xT7h4T via @YouTube
@betaboechat https://t.co/AMCmxJbSvR
The genetics of obesity: from discovery to biology go.nature.com/4h5x9os #WorldObesityDay Free to read here: rdcu.be/eb3bF
@whiskytast @miamologue Combien sont satisfaits et n'ont jamais repris pour combien d'échecs ? Sources : https://t.co/dTHqbWkcJl https://t.co/yrxdc0TnaY https://t.co/z6x1zUheXG https://t.co/llb3eeXeAL https://t.co/Us7eTGn0ir Et tu peux en trouver encore des tas...
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2) A revolution in obesity treatment by Ildiko Lingvay & Shubham Agarwal 3) The genetics of #obesity: from discovery to biology by Ruth Loos and Giles Yeo 4) Existing and Emerging Molecular Targets for the Pharmacotherapy of Obesity by Glykofrydi et al https://t.co/r4y084pXcW
The genetics of obesity: from discovery to biology | Nature Reviews Genetics https://t.co/k5q4PO3bmT time to recognise the complexity of Obesity @CiceroMD @DrAseemMalhotra #Obes
The genetics of obesity: from discovery to biology https://t.co/VtXKHlHhiU https://t.co/tCPy9y12Ti
@datepsych Actually, "40% to 70%" Loos, R.J.F., Yeo, G.S.H. The genetics of obesity: from discovery to biology. Nat Rev Genet 23, 120–133 (2022). "from 30% to 55%" Bouchard, C. (2021). Genetics of obesity: What we have learned over decades of research. Obesity, 29(5), 802–820.
The genetics of obesity: from discovery to biology | Nature Reviews Genetics https://t.co/OpZfXeVoco
@JayDShahMD Yup: @askdrfatima @MarsApovian Experts estimate that genetics contribute to 40-70% of the variability we see in BMI. But our genetics haven’t changed so this is just the 1st sentence of the paragraph so to speak. Read up here: https://t.co/blzGqONXeI
RT @NatureRevGenet: The genetics of obesity: from discovery to biology https://t.co/Fi7W9lE78Q #Review by Ruth J. F. Loos & @gilesyeo @Met…
RT @NatureRevGenet: The genetics of obesity: from discovery to biology https://t.co/Fi7W9lE78Q #Review by Ruth J. F. Loos & @gilesyeo @Met…
RT @NatureRevGenet: The genetics of obesity: from discovery to biology https://t.co/Fi7W9lE78Q #Review by Ruth J. F. Loos & @gilesyeo @Met…
RT @NatureRevGenet: The genetics of obesity: from discovery to biology https://t.co/Fi7W9lE78Q #Review by Ruth J. F. Loos & @gilesyeo @Met…
RT @NatureRevGenet: The genetics of obesity: from discovery to biology https://t.co/Fi7W9lE78Q #Review by Ruth J. F. Loos & @gilesyeo @Met…
RT @Metabolcenter: A review so nice @NatureRevGenet tweeted it twice!
RT @Metabolcenter: A review so nice @NatureRevGenet tweeted it twice!
RT @NatureRevGenet: The genetics of obesity: from discovery to biology https://t.co/Fi7W9lE78Q #Review by Ruth J. F. Loos & @gilesyeo @Met…
RT @Metabolcenter: A review so nice @NatureRevGenet tweeted it twice!
RT @NatureRevGenet: The genetics of obesity: from discovery to biology https://t.co/Fi7W9lE78Q #Review by Ruth J. F. Loos & @gilesyeo @Met…
RT @Metabolcenter: A review so nice @NatureRevGenet tweeted it twice!
RT @NatureRevGenet: The genetics of obesity: from discovery to biology https://t.co/Fi7W9lE78Q #Review by Ruth J. F. Loos & @gilesyeo @Met…
RT @NatureRevGenet: The genetics of obesity: from discovery to biology https://t.co/Fi7W9lE78Q #Review by Ruth J. F. Loos & @gilesyeo @Met…
RT @Metabolcenter: A review so nice @NatureRevGenet tweeted it twice!
A review so nice @NatureRevGenet tweeted it twice!
RT @NatureRevGenet: The genetics of obesity: from discovery to biology https://t.co/Fi7W9lE78Q #Review by Ruth J. F. Loos & @gilesyeo @Met…
RT @NatureRevGenet: The genetics of obesity: from discovery to biology https://t.co/Fi7W9lE78Q #Review by Ruth J. F. Loos & @gilesyeo @Met…
RT @NatureRevGenet: The genetics of obesity: from discovery to biology https://t.co/Fi7W9lE78Q #Review by Ruth J. F. Loos & @gilesyeo @Met…
RT @NatureRevGenet: The genetics of obesity: from discovery to biology https://t.co/Fi7W9lE78Q #Review by Ruth J. F. Loos & @gilesyeo @Met…
RT @NatureRevGenet: The genetics of obesity: from discovery to biology https://t.co/Fi7W9lE78Q #Review by Ruth J. F. Loos & @gilesyeo @Met…
RT @NatureRevGenet: The genetics of obesity: from discovery to biology https://t.co/Fi7W9lE78Q #Review by Ruth J. F. Loos & @gilesyeo @Met…
RT @NatureRevGenet: The genetics of obesity: from discovery to biology https://t.co/Fi7W9lE78Q #Review by Ruth J. F. Loos & @gilesyeo @Met…
RT @NatureRevGenet: The genetics of obesity: from discovery to biology https://t.co/Fi7W9lE78Q #Review by Ruth J. F. Loos & @gilesyeo @Met…
RT @NatureRevGenet: The genetics of obesity: from discovery to biology https://t.co/Fi7W9lE78Q #Review by Ruth J. F. Loos & @gilesyeo @Met…
RT @NatureRevGenet: The genetics of obesity: from discovery to biology https://t.co/Fi7W9lE78Q #Review by Ruth J. F. Loos & @gilesyeo @Met…
RT @NatureRevGenet: The genetics of obesity: from discovery to biology https://t.co/Fi7W9lE78Q #Review by Ruth J. F. Loos & @gilesyeo @Met…
The genetics of obesity: from discovery to biology https://t.co/Fi7W9lE78Q #Review by Ruth J. F. Loos & @gilesyeo @Metabolcenter @IcahnMountSinai @MRL_Cam Free to read here: https://t.co/pvK6Ea8wpS
@LuaWilkinson Recent review papers: https://t.co/Lz4NzOJ0Na https://t.co/xdiQOJ9D3J Endo Soc statement on obesity pathogenesis: https://t.co/G9IDgG1CGe Technical review of VMH lesion studies: https://t.co/rHoZyhZW9G Identification of leptin: https://t.co/rOOHytt6ta
RT @MichaelAlbertMD: @MiriamBerchuk @MichelleCardel @EmilyDhurandhar @sguyenet The two best reviews on this topic: [1] Variability in the H…
@MiriamBerchuk @MichelleCardel @EmilyDhurandhar @sguyenet The two best reviews on this topic: [1] Variability in the Heritability of Body Mass Index: A Systematic Review and Meta-Regression https://t.co/gRT3xvXlrD [2] The genetics of obesity: from discovery to biology https://t.co/HD8gHEroeu
RT @WiringTheBrain: The genetics of obesity: from discovery to biology https://t.co/3uSUxjWCIi - excellent review of progress over 30 years…
RT @WiringTheBrain: The genetics of obesity: from discovery to biology https://t.co/3uSUxjWCIi - excellent review of progress over 30 years…
RT @WiringTheBrain: The genetics of obesity: from discovery to biology https://t.co/3uSUxjWCIi - excellent review of progress over 30 years…
RT @ObesityMS: The genetics of obesity: from discovery to biology https://t.co/cwJbhFKapr https://t.co/ovsAF79Qso
RT @eurogene: The genetics of obesity: from discovery to biology | Nature Reviews Genetics https://t.co/gHboJGyk1R by @GilesYeo & Ruth Loos…
RT @eurogene: The genetics of obesity: from discovery to biology | Nature Reviews Genetics https://t.co/gHboJGyk1R by @GilesYeo & Ruth Loos…
RT @eurogene: The genetics of obesity: from discovery to biology | Nature Reviews Genetics https://t.co/gHboJGyk1R by @GilesYeo & Ruth Loos…
RT @eurogene: The genetics of obesity: from discovery to biology | Nature Reviews Genetics https://t.co/gHboJGyk1R by @GilesYeo & Ruth Loos…
RT @eurogene: The genetics of obesity: from discovery to biology | Nature Reviews Genetics https://t.co/gHboJGyk1R by @GilesYeo & Ruth Loos…
RT @eurogene: The genetics of obesity: from discovery to biology | Nature Reviews Genetics https://t.co/gHboJGyk1R by @GilesYeo & Ruth Loos…
RT @ObesityMS: The genetics of obesity: from discovery to biology https://t.co/cwJbhFKapr https://t.co/ovsAF79Qso
RT @ObesityMS: The genetics of obesity: from discovery to biology https://t.co/cwJbhFKapr https://t.co/ovsAF79Qso
RT @ObesityMS: The genetics of obesity: from discovery to biology https://t.co/cwJbhFKapr https://t.co/ovsAF79Qso
RT @ObesityMS: The genetics of obesity: from discovery to biology https://t.co/cwJbhFKapr https://t.co/ovsAF79Qso
RT @ObesityMS: The genetics of obesity: from discovery to biology https://t.co/cwJbhFKapr https://t.co/ovsAF79Qso
RT @ObesityMS: The genetics of obesity: from discovery to biology https://t.co/cwJbhFKapr https://t.co/ovsAF79Qso
RT @ObesityMS: The genetics of obesity: from discovery to biology https://t.co/cwJbhFKapr https://t.co/ovsAF79Qso
RT @ObesityMS: The genetics of obesity: from discovery to biology https://t.co/cwJbhFKapr https://t.co/ovsAF79Qso
RT @ObesityMS: The genetics of obesity: from discovery to biology https://t.co/cwJbhFKapr https://t.co/ovsAF79Qso
RT @ObesityMS: The genetics of obesity: from discovery to biology https://t.co/cwJbhFKapr https://t.co/ovsAF79Qso
RT @ObesityMS: The genetics of obesity: from discovery to biology https://t.co/cwJbhFKapr https://t.co/ovsAF79Qso
RT @ObesityMS: The genetics of obesity: from discovery to biology https://t.co/cwJbhFKapr https://t.co/ovsAF79Qso
RT @ObesityMS: The genetics of obesity: from discovery to biology https://t.co/cwJbhFKapr https://t.co/ovsAF79Qso
The genetics of obesity: from discovery to biology https://t.co/cwJbhFKapr https://t.co/ovsAF79Qso
RT @WiringTheBrain: The genetics of obesity: from discovery to biology https://t.co/3uSUxjWCIi - excellent review of progress over 30 years…
RT @eurogene: The genetics of obesity: from discovery to biology | Nature Reviews Genetics https://t.co/gHboJGyk1R by @GilesYeo & Ruth Loos…
RT @NatureRevGenet: Today is #WorldObesityDay! Read all about 'The genetics of obesity: from discovery to biology' https://t.co/Fi7W9lDzji…
RT @NatureRevGenet: Today is #WorldObesityDay! Read all about 'The genetics of obesity: from discovery to biology' https://t.co/Fi7W9lDzji…
RT @NatureRevGenet: Today is #WorldObesityDay! Read all about 'The genetics of obesity: from discovery to biology' https://t.co/Fi7W9lDzji…
RT @NatureRevGenet: Today is #WorldObesityDay! Read all about 'The genetics of obesity: from discovery to biology' https://t.co/Fi7W9lDzji…
RT @NatureRevGenet: Today is #WorldObesityDay! Read all about 'The genetics of obesity: from discovery to biology' https://t.co/Fi7W9lDzji…
RT @NatureRevGenet: Today is #WorldObesityDay! Read all about 'The genetics of obesity: from discovery to biology' https://t.co/Fi7W9lDzji…
RT @NatureRevGenet: Today is #WorldObesityDay! Read all about 'The genetics of obesity: from discovery to biology' https://t.co/Fi7W9lDzji…
RT @NatureRevGenet: Today is #WorldObesityDay! Read all about 'The genetics of obesity: from discovery to biology' https://t.co/Fi7W9lDzji…
RT @NatureRevGenet: Today is #WorldObesityDay! Read all about 'The genetics of obesity: from discovery to biology' https://t.co/Fi7W9lDzji…
RT @NatureRevGenet: Today is #WorldObesityDay! Read all about 'The genetics of obesity: from discovery to biology' https://t.co/Fi7W9lDzji…
RT @NatureRevGenet: Today is #WorldObesityDay! Read all about 'The genetics of obesity: from discovery to biology' https://t.co/Fi7W9lDzji…
RT @NatureRevGenet: Today is #WorldObesityDay! Read all about 'The genetics of obesity: from discovery to biology' https://t.co/Fi7W9lDzji…
RT @NatureRevGenet: Today is #WorldObesityDay! Read all about 'The genetics of obesity: from discovery to biology' https://t.co/Fi7W9lDzji…
RT @NatureRevGenet: Today is #WorldObesityDay! Read all about 'The genetics of obesity: from discovery to biology' https://t.co/Fi7W9lDzji…
RT @NatureRevGenet: Today is #WorldObesityDay! Read all about 'The genetics of obesity: from discovery to biology' https://t.co/Fi7W9lDzji…
RT @NatureRevGenet: Today is #WorldObesityDay! Read all about 'The genetics of obesity: from discovery to biology' https://t.co/Fi7W9lDzji…
RT @NatureRevGenet: Today is #WorldObesityDay! Read all about 'The genetics of obesity: from discovery to biology' https://t.co/Fi7W9lDzji…
RT @eurogene: The genetics of obesity: from discovery to biology | Nature Reviews Genetics https://t.co/gHboJGyk1R by @GilesYeo & Ruth Loos…
RT @eurogene: The genetics of obesity: from discovery to biology | Nature Reviews Genetics https://t.co/gHboJGyk1R by @GilesYeo & Ruth Loos…
RT @eurogene: The genetics of obesity: from discovery to biology | Nature Reviews Genetics https://t.co/gHboJGyk1R by @GilesYeo & Ruth Loos…
RT @eurogene: The genetics of obesity: from discovery to biology | Nature Reviews Genetics https://t.co/gHboJGyk1R by @GilesYeo & Ruth Loos…
RT @eurogene: The genetics of obesity: from discovery to biology | Nature Reviews Genetics https://t.co/gHboJGyk1R by @GilesYeo & Ruth Loos…
RT @eurogene: The genetics of obesity: from discovery to biology | Nature Reviews Genetics https://t.co/gHboJGyk1R by @GilesYeo & Ruth Loos…
RT @eurogene: The genetics of obesity: from discovery to biology | Nature Reviews Genetics https://t.co/gHboJGyk1R by @GilesYeo & Ruth Loos…
RT @NeilFlochMD: The #genetics of #obesity: from discovery to biology | Nature Reviews Genetics https://t.co/4xjgePY8SH
The #genetics of #obesity: from discovery to biology | Nature Reviews Genetics https://t.co/4xjgePY8SH
The genetics of obesity: from discovery to biology | Nature Reviews Genetics https://t.co/gHboJGyk1R by @GilesYeo & Ruth Loos - #openaccess
Dans cet article, je reviens sur la génétique et la biochimie de l'obésité à l'aide d'une revue récente parue dans @NatureGenet par @GilesYeo et Ruth Loss. https://t.co/Jifqg45CT5
@whsource @MichaelMindrum @JohnSpeakman4 @davidludwigmd @KevinH_PhD It's not the GWAS that is hypothesis-driven, but what the genes identified do and, yah, where they do it. As Loos and Yeo say, that's the "arduous task." FTO, e.g. 1st ob-related gene ID'd by GWAS, largest effect, mechanism and location still a guess. https://t.co/xAbtElc1Wy https://t.co/xefbfKFyS7