Nutrients September 2021 PMID 34579042

The Effects of Intermittent Fasting on Brain and Cognitive Function.

Jip Gudden, Alejandro Arias Vasquez, Mirjam Bloemendaal

Mentions

114
Peak: 16 in Sep 2021
across 5 sources since Aug 2021

Extended reach

236,119
potential audience

Total likes

296

Video views

3,113

Mentions per month

Aug 2021 – May 2025

Where it's discussed

  • X / Twitter56 posts
  • News45 articles
  • YouTube6 videos
  • Blogs5 articles
  • Bluesky2 posts

AI synopsis

What people are saying

Overall, the digital discussions reveal a balanced interest in the biological mechanisms and potential benefits of intermittent fasting, supported by references to biochemical pathways and clinical evidence. The tone varies from curiosity to cautious optimism, with posts mentioning specific effects like cellular and circadian mechanisms and highlighting ongoing research efforts, illustrating moderate engagement and perceived impact on future research directions.

AgreementModerate agreement

Most discussions acknowledge the findings, with some highlighting specific benefits to brain health and mechanisms of fasting, but there is also some skepticism about definitive effects on cognition.

InterestModerate interest

Participants show moderate curiosity, referencing various pathways, mechanisms, and implications for neurological conditions, indicating a genuine interest.

EngagementModerate engagement

Many responses mention detailed biochemical pathways, clinical benefits, and ongoing reviews, reflecting a thoughtful level of engagement rather than superficial comments.

ImpactModerate impact

The discussions suggest the research could influence future studies and health practices by focusing on neurobiological benefits and mechanisms, though some posts remain cautious about conclusive effects.

Abstract in brief

  • Intermittent fasting (IF), which involves alternating periods of calorie restriction with normal eating, shows promising neurobiological benefits in animal studies, potentially influencing brain health through metabolic, cellular, and circadian mechanisms.
  • Current clinical evidence indicates that IF can improve symptoms and disease progression in conditions like epilepsy, Alzheimer’s, and multiple sclerosis, while animal research suggests possible benefits for diseases such as Parkinson’s, stroke, autism, and mood disorders.
  • Future research needs to clarify if IF benefits are consistent regardless of age or obesity, and should focus on long-term impacts, variations in fasting protocols, nutrient intake, and conducting more rigorous studies like randomized controlled trials.]

Top posts

Most liked on X and Bluesky
Doç. Dr. Işıl
@IsilDr22 · X

Çalışmalarda süreli açlığın beyin üzerindeki olumlu etkileri ve bazı beyin patolojilerinde iyileşme sağlayabilecegi gösterilmiş ancak burada bahsedilen bunun ötesinde.Bedensel girdilerin azalması+ https://t.co/dUMgZFsXnQ

Apr 2, 2022 · 92 likes · 9 shares · 29,293 followers View post →
Mirjam Bloemendaal
@mirjam_bloem · X

out now: our review on the effects of intermittent fasting on brain and cognitive functioning

Sep 14, 2021 · 27 likes · 5 shares · 821 followers View post →
htw
@heniek_htw · X

The Effects of Intermittent Fasting on Brain and Cognitive Function ➡️ We do so by summarizing the effects of IF which through metabolic, cellular, and circadian mechanisms lead to anatomical and functional changes in the brain. https://t.co/TollZ0tsBF

Sep 10, 2021 · 19 likes · 5 shares · 11,262 followers View post →
manvir singh
@mnvrsngh · X

References: - https://t.co/MuSLhJS7AK… - https://t.co/jQuFRm9bmZ… - https://t.co/aEgG10FiLA… - https://t.co/fgUQakpeTm

Aug 10, 2022 · 15 likes · 1 share · 14,439 followers View post →
Nutrients MDPI
@Nutrients_MDPI · X

Jul 17, 2024 · 5 likes · 5 shares · 11,215 followers View post →
htw
@heniek_htw · X

Sep 10, 2021 · 4 likes · 1 share · 11,262 followers View post →

All mentions

bioRxiv Neuroscience
@biorxiv-neursci.bsky.social · Bluesky

Succinate Modulation as a Novel Mechanism Underlying the Effects of Intermittent Fasting on Brain Function and Metabolism in Diet-Induced Obesity https://www.biorxiv.org/content/10.1101/2025.05.16.654006v1

May 21, 2025 · 1 like View post →
bioRxivpreprint
@biorxivpreprint.bsky.social · Bluesky

Succinate Modulation as a Novel Mechanism Underlying the Effects of Intermittent Fasting on Brain Function and Metabolism in Diet-Induced Obesity https://www.biorxiv.org/content/10.1101/2025.05.16.654006v1

May 21, 2025 View post →
peninnah rachel
@peninnahrachel · X

The Effects of Intermittent Fasting on Brain and Cognitive Function https://t.co/wJ8xbB2BxD

May 10, 2025 · 882 followers View post →
Maardawasnie 5.0
@maardawasnie · X

@TheRealEenhoorn @MichielBilstra https://t.co/irGavzASdR

May 9, 2025 · 1 like · 17,230 followers View post →
Toplumsal Harekat
@t_harekat · X

https://t.co/efWC818L1M

Feb 28, 2025 · 1 like · 2,225 followers View post →
Dog Playing Piano
@DogPlayingPiano · X

@BioavailableNd You know intermittent fasting has similar effects? https://t.co/m890qiB8M3 https://t.co/fNe5fGOsj6

Nov 30, 2024 · 774 followers View post →
Dr. Robin J. Malloy
@dr_robinmalloy · X

Biochemical pathways involved in the metabolic switch. https://t.co/U7Ei1fCAhC #Epigenetics #microrna #neuroscience #MedTwitter #ImmuneSystem #Nutrition #cancer #schizophrenia #microglia #pregnancy #ArtificialIntelligence https://t.co/2hO0uSW6OV

Nov 8, 2024 · 198 followers View post →
Dr. Robin J. Malloy
@dr_robinmalloy · X

Different forms of intermittent fasting. https://t.co/U7Ei1fCAhC #Epigenetics #microrna #neuroscience #MedTwitter #ImmuneSystem #Nutrition #cancer #schizophrenia #microglia #pregnancy #ArtificialIntelligence https://t.co/TieofXdgP4

Nov 8, 2024 · 198 followers View post →
Mar Diaz
@LaLaMarDiaz · X

RT @mnvrsngh: References: - https://t.co/MuSLhJS7AK… - https://t.co/jQuFRm9bmZ… - https://t.co/aEgG10FiLA… - https://t.co/fgUQakpeTm

Aug 8, 2024 · 1 share · 53 followers View post →
Benjamin Horne
@DrBenjaminHorne · X

Effects of #IntermittentFasting on Cognition: "Our review shows...no clear evidence of a positive short-term effect of [fasting] on cognition in healthy subjects. Clinical studies show benefits for epilepsy, Alzheimer’s..." & MS https://t.co/0HCpJkkvnj @Nutrients_MDPI

Jul 26, 2024 · 1,541 followers View post →
Benjamin Horne
@DrBenjaminHorne · X

RT @Nutrients_MDPI:

Jul 26, 2024 · 5 shares · 1,541 followers View post →
.c.a.r.l.o.s
@galantee28 · X

RT @Nutrients_MDPI:

Jul 18, 2024 · 5 shares · 34 followers View post →
Rodrigo Nunes Cal
@CalZole · X

RT @Nutrients_MDPI:

Jul 17, 2024 · 5 shares · 2,863 followers View post →
Manoj Mayogi Mishra
@mayogisense · X

RT @Nutrients_MDPI:

Jul 17, 2024 · 5 shares · 573 followers View post →
Martin
@MartinMeinung · X

Tierstudien zeigen Mechanismen, mit denen Parkinson-Krankheit, ischämischer Schlaganfall, Autismus-Spektrum-Störung sowie Stimmungs- und Angststörungen von Intervall Fasten (IF) profitieren könnten https://t.co/L58aZkK7vu

Jul 17, 2024 · 1 like · 11,253 followers View post →
Fernando Vidal-Ostos De Lara
@drvidalostos · X

RT @Nutrients_MDPI:

Jul 17, 2024 · 5 shares · 424 followers View post →
Nutrients MDPI
@Nutrients_MDPI · X

Jul 17, 2024 · 5 likes · 5 shares · 11,215 followers View post →
Ravi Kumar
@RaviKum13662523 · X

The Effects of Intermittent Fasting on Brain and Cognitive Function. https://t.co/jTLPHnvo2J

Apr 18, 2024 View post →
Birgitta Neher
@NeBirgitta · X

The Effects of Intermittent Fasting on Brain and Cognitive Function https://t.co/u2aF94jgnx

Feb 29, 2024 · 2,843 followers View post →
Sandra minguez
@Sandraming68789 · X

3. Puede prevenir el desarrollo de enfermedades neurológicas https://t.co/JPSCVsmRBC #intermittentfasting #Neurology

Dec 12, 2023 View post →
DrRPalmquist
@DrPalmquist · X

The Effects of Intermittent Fasting on Brain and Cognitive Function https://t.co/tmFVxSxGxc

Dec 6, 2023 · 3 likes · 3,159 followers View post →
G K Y
@_gopiy · X

https://t.co/tax3XaIc84 #IntermittentFasting #ADHD #ASD https://t.co/oFAhJOvT7D

May 14, 2023 · 2 likes · 432 followers View post →
Artemisa
@Artha_misa · X

@ghunter_frager Y más https://t.co/VSCjspQ8B8

Nov 14, 2022 · 1 like · 7,237 followers View post →
Startup
@StartupSanatana · X

@hamsanandi The Effects of Intermittent Fasting on Brain and Cognitive Function https://t.co/jw1NGD4yl8

Oct 26, 2022 · 2,810 followers View post →
manvir singh
@mnvrsngh · X

References: - https://t.co/MuSLhJS7AK… - https://t.co/jQuFRm9bmZ… - https://t.co/aEgG10FiLA… - https://t.co/fgUQakpeTm

Aug 10, 2022 · 15 likes · 1 share · 14,439 followers View post →
Alejandro Arias
@TulipanTricolor · X

RT @mirjam_bloem: Het resultaat van Jips werk in de werkplaats van @UniversiteitNL

May 18, 2022 · 1 share · 282 followers View post →
Mirjam Bloemendaal
@mirjam_bloem · X

Het resultaat van Jips werk in de werkplaats van @UniversiteitNL

May 17, 2022 · 3 likes · 1 share · 821 followers View post →
Zöhre Kanar
@KanarZohre · X

RT @UzunDr: Çalışmalarda süreli açlığın beyin üzerindeki olumlu etkileri ve bazı beyin patolojilerinde iyileşme sağlayabilecegi gösterilmiş…

Apr 3, 2022 · 9 shares · 186 followers View post →
Eda
@bnoktaeda · X

RT @UzunDr: Çalışmalarda süreli açlığın beyin üzerindeki olumlu etkileri ve bazı beyin patolojilerinde iyileşme sağlayabilecegi gösterilmiş…

Apr 3, 2022 · 9 shares · 23 followers View post →
ϜϓſϞ
@oyuncak_dunya_ · X

RT @UzunDr: Çalışmalarda süreli açlığın beyin üzerindeki olumlu etkileri ve bazı beyin patolojilerinde iyileşme sağlayabilecegi gösterilmiş…

Apr 2, 2022 · 9 shares · 3,527 followers View post →
adilce bir yaşam sürmek
@harunar87731903 · X

RT @UzunDr: Çalışmalarda süreli açlığın beyin üzerindeki olumlu etkileri ve bazı beyin patolojilerinde iyileşme sağlayabilecegi gösterilmiş…

Apr 2, 2022 · 9 shares · 2,242 followers View post →
Şimşek Çakar
@yldrmztrk8 · X

https://t.co/LhMypQq0IG

Apr 2, 2022 · 12,598 followers View post →
Şimşek Çakar
@yldrmztrk8 · X

RT @UzunDr: Çalışmalarda süreli açlığın beyin üzerindeki olumlu etkileri ve bazı beyin patolojilerinde iyileşme sağlayabilecegi gösterilmiş…

Apr 2, 2022 · 9 shares · 12,598 followers View post →
Kedilere Fısıldayan Kadın
@sour1881 · X

RT @UzunDr: Çalışmalarda süreli açlığın beyin üzerindeki olumlu etkileri ve bazı beyin patolojilerinde iyileşme sağlayabilecegi gösterilmiş…

Apr 2, 2022 · 9 shares · 1,911 followers View post →
Hulin...
@Rukiyestn7 · X

RT @UzunDr: Çalışmalarda süreli açlığın beyin üzerindeki olumlu etkileri ve bazı beyin patolojilerinde iyileşme sağlayabilecegi gösterilmiş…

Apr 2, 2022 · 9 shares · 629 followers View post →
Doç. Dr. Işıl
@IsilDr22 · X

Çalışmalarda süreli açlığın beyin üzerindeki olumlu etkileri ve bazı beyin patolojilerinde iyileşme sağlayabilecegi gösterilmiş ancak burada bahsedilen bunun ötesinde.Bedensel girdilerin azalması+ https://t.co/dUMgZFsXnQ

Apr 2, 2022 · 92 likes · 9 shares · 29,293 followers View post →
Mirjam Bloemendaal
@mirjam_bloem · X

@nieuwenhuijze @EditieNL @RTLnieuws Door periodiek vasten kom je ketose door de afwezigheid van eten/koolhydraten als bron van energie. Zie ons review hierover: https://t.co/Cku3oPm9JL

Feb 1, 2022 · 1 like · 821 followers View post →
SorenCS
@SorenCS1 · X

RT @agingdoc1: The Effects of Intermittent Fasting on Brain and Cognitive Function https://t.co/UINCJudGGq

Nov 16, 2021 · 2 shares · 217 followers View post →
The Phoenix Lab
@The_Phoenix_Lab · X

RT @agingdoc1: The Effects of Intermittent Fasting on Brain and Cognitive Function https://t.co/UINCJudGGq

Nov 16, 2021 · 2 shares · 210 followers View post →
Agingdoc
@agingdoc1 · X

The Effects of Intermittent Fasting on Brain and Cognitive Function https://t.co/UINCJudGGq

Nov 16, 2021 · 3 likes · 2 shares · 41,316 followers View post →
Peter Dingle (PhD)
@drdingle · X

The Effects of Intermittent Fasting on Brain and Cognitive Function https://t.co/TM84tE3Uut #mdpinutrients via @Nutrients_MDPI

Oct 22, 2021 · 2 likes · 2,299 followers View post →
#Autism
@Autism_Journal · X

The Effects of Intermittent Fasting on Brain and Cognitive Function https://t.co/ODTwKa9H9i #PubMed #Autism

Sep 29, 2021 · 388 followers View post →
Chris Trejbal, CNP, NNCP, PTS, RNT
@TrejbalChris · X

The Effects of Intermittent Fasting on Brain and Cognitive Function https://t.co/TLgXdLyAzk

Sep 17, 2021 · 365 followers View post →
湘南なぎさクラブ*パーキンソン病患者家族会
@ShonanNagisaC · X

断食が脳・認知機能に及ぼす影響について 「断食パターン、総カロリー摂取量、および特定の栄養素の摂取量の違いが、IF(間欠的断食)の成功に関連する要素である可能性。長期的な研究と無作為化臨床試験によって脳関連疾患の発症と進展に対するIFの長期的な効果」 nutrients https://t.co/6OY7sg0spo

Sep 15, 2021 · 76 followers View post →
Lieneke Janssen
@lkjanssen · X

RT @mirjam_bloem: out now: our review on the effects of intermittent fasting on brain and cognitive functioning

Sep 14, 2021 · 5 shares · 924 followers View post →
Wanda Zarzycka
@WandaZarzycka · X

RT @mirjam_bloem: out now: our review on the effects of intermittent fasting on brain and cognitive functioning

Sep 14, 2021 · 5 shares · 69 followers View post →
Marcus Böhme
@BoehmeMarcus · X

RT @mirjam_bloem: out now: our review on the effects of intermittent fasting on brain and cognitive functioning

Sep 14, 2021 · 5 shares · 4,320 followers View post →
Isabella Wagner
@isabellawagnr · X

RT @mirjam_bloem: out now: our review on the effects of intermittent fasting on brain and cognitive functioning

Sep 14, 2021 · 5 shares · 864 followers View post →
Mirjam Bloemendaal
@mirjam_bloem · X

out now: our review on the effects of intermittent fasting on brain and cognitive functioning

Sep 14, 2021 · 27 likes · 5 shares · 821 followers View post →
emerson florez
@laniga771209 · X

RT @heniek_htw: The Effects of Intermittent Fasting on Brain and Cognitive Function ➡️ We do so by summarizing the effects of IF which thr…

Sep 11, 2021 · 5 shares · 24 followers View post →
plantbhai - 3bdu Al-Hakim
@HakimBGZ · X

RT @heniek_htw: The Effects of Intermittent Fasting on Brain and Cognitive Function ➡️ We do so by summarizing the effects of IF which thr…

Sep 10, 2021 · 5 shares · 2,738 followers View post →
Frederic Danel
@Frederic_Danel · X

RT @heniek_htw:

Sep 10, 2021 · 1 share · 336 followers View post →
Andres Felipe
@Anferupu · X

RT @heniek_htw: The Effects of Intermittent Fasting on Brain and Cognitive Function ➡️ We do so by summarizing the effects of IF which thr…

Sep 10, 2021 · 5 shares · 52 followers View post →
Oscar Andres
@OscarAndresMD · X

RT @heniek_htw: The Effects of Intermittent Fasting on Brain and Cognitive Function ➡️ We do so by summarizing the effects of IF which thr…

Sep 10, 2021 · 5 shares · 556 followers View post →
Constanza G. ☀️⚡️
@constanzag77 · X

RT @heniek_htw: The Effects of Intermittent Fasting on Brain and Cognitive Function ➡️ We do so by summarizing the effects of IF which thr…

Sep 10, 2021 · 5 shares · 3,733 followers View post →
htw
@heniek_htw · X

Sep 10, 2021 · 4 likes · 1 share · 11,262 followers View post →
htw
@heniek_htw · X

The Effects of Intermittent Fasting on Brain and Cognitive Function ➡️ We do so by summarizing the effects of IF which through metabolic, cellular, and circadian mechanisms lead to anatomical and functional changes in the brain. https://t.co/TollZ0tsBF

Sep 10, 2021 · 19 likes · 5 shares · 11,262 followers View post →
Preprints.org
@Preprints_org · X

The Effects of Intermittent Fasting on Brain and Cognitive Function https://t.co/S9o3ybIeGR #MedPreprints #PharmaPreprints #PreprintsOrg @TulipanTricolor @mirjam_bloem

Aug 27, 2021 · 3,984 followers View post →