The Effects of Intermittent Fasting on Brain and Cognitive Function.
Jip Gudden, Alejandro Arias Vasquez, Mirjam Bloemendaal
September 2021 NutrientsSynopsis of Social media discussions
Overall, the digital discussions reveal a balanced interest in the biological mechanisms and potential benefits of intermittent fasting, supported by references to biochemical pathways and clinical evidence. The tone varies from curiosity to cautious optimism, with posts mentioning specific effects like cellular and circadian mechanisms and highlighting ongoing research efforts, illustrating moderate engagement and perceived impact on future research directions.
Agreement
Moderate agreementMost discussions acknowledge the findings, with some highlighting specific benefits to brain health and mechanisms of fasting, but there is also some skepticism about definitive effects on cognition.
Interest
Moderate level of interestParticipants show moderate curiosity, referencing various pathways, mechanisms, and implications for neurological conditions, indicating a genuine interest.
Engagement
Moderate level of engagementMany responses mention detailed biochemical pathways, clinical benefits, and ongoing reviews, reflecting a thoughtful level of engagement rather than superficial comments.
Impact
Moderate level of impactThe discussions suggest the research could influence future studies and health practices by focusing on neurobiological benefits and mechanisms, though some posts remain cautious about conclusive effects.
Social Mentions
YouTube
6 Videos
Bluesky
2 Posts
56 Posts
Blogs
5 Articles
News
45 Articles
Metrics
Video Views
3,113
Total Likes
296
Extended Reach
236,119
Social Features
114
Timeline: Posts about article
Top Social Media Posts
Posts referencing the article
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Succinate Modulation as a Novel Mechanism Underlying the Effects of Intermittent Fasting on Brain Function and Metabolism in Diet-Induced Obesity https://www.biorxiv.org/content/10.1101/2025.05.16.654006v1
view full postMay 21, 2025
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bioRxivpreprint
@biorxivpreprint.bsky.social (Bluesky)Succinate Modulation as a Novel Mechanism Underlying the Effects of Intermittent Fasting on Brain Function and Metabolism in Diet-Induced Obesity https://www.biorxiv.org/content/10.1101/2025.05.16.654006v1
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peninnah rachel
@peninnahrachel (Twitter)The Effects of Intermittent Fasting on Brain and Cognitive Function https://t.co/wJ8xbB2BxD
view full postMay 10, 2025
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Maardawasnie 5.0
@maardawasnie (Twitter)@TheRealEenhoorn @MichielBilstra https://t.co/irGavzASdR
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Toplumsal Harekat
@t_harekat (Twitter)https://t.co/efWC818L1M
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Dog Playing Piano
@DogPlayingPiano (Twitter)@BioavailableNd You know intermittent fasting has similar effects? https://t.co/m890qiB8M3 https://t.co/fNe5fGOsj6
view full postNovember 30, 2024
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Dr. Robin J. Malloy
@dr_robinmalloy (Twitter)Biochemical pathways involved in the metabolic switch. https://t.co/U7Ei1fCAhC #Epigenetics #microrna #neuroscience #MedTwitter #ImmuneSystem #Nutrition #cancer #schizophrenia #microglia #pregnancy #ArtificialIntelligence https://t.co/2hO0uSW6OV
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Dr. Robin J. Malloy
@dr_robinmalloy (Twitter)Different forms of intermittent fasting. https://t.co/U7Ei1fCAhC #Epigenetics #microrna #neuroscience #MedTwitter #ImmuneSystem #Nutrition #cancer #schizophrenia #microglia #pregnancy #ArtificialIntelligence https://t.co/TieofXdgP4
view full postNovember 8, 2024
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Mar Diaz
@LaLaMarDiaz (Twitter)RT @mnvrsngh: References: - https://t.co/MuSLhJS7AK… - https://t.co/jQuFRm9bmZ… - https://t.co/aEgG10FiLA… - https://t.co/fgUQakpeTm
view full postAugust 8, 2024
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Benjamin Horne
@DrBenjaminHorne (Twitter)Effects of #IntermittentFasting on Cognition: "Our review shows...no clear evidence of a positive short-term effect of [fasting] on cognition in healthy subjects. Clinical studies show benefits for epilepsy, Alzheimer’s..." & MS https://t.co/0HCpJkkvnj @Nutrients_MDPI
view full postJuly 26, 2024
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Benjamin Horne
@DrBenjaminHorne (Twitter)RT @Nutrients_MDPI:
view full postJuly 26, 2024
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.c.a.r.l.o.s
@galantee28 (Twitter)RT @Nutrients_MDPI:
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Rodrigo Nunes Cal
@CalZole (Twitter)RT @Nutrients_MDPI:
view full postJuly 17, 2024
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Manoj Mayogi Mishra
@mayogisense (Twitter)RT @Nutrients_MDPI:
view full postJuly 17, 2024
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Martin
@MartinMeinung (Twitter)Tierstudien zeigen Mechanismen, mit denen Parkinson-Krankheit, ischämischer Schlaganfall, Autismus-Spektrum-Störung sowie Stimmungs- und Angststörungen von Intervall Fasten (IF) profitieren könnten https://t.co/L58aZkK7vu
view full postJuly 17, 2024
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Fernando Vidal-Ostos De Lara
@drvidalostos (Twitter)RT @Nutrients_MDPI:
view full postJuly 17, 2024
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Nutrients MDPI
@Nutrients_MDPI (Twitter)July 17, 2024
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Ravi Kumar
@RaviKum13662523 (Twitter)The Effects of Intermittent Fasting on Brain and Cognitive Function. https://t.co/jTLPHnvo2J
view full postApril 18, 2024
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Birgitta Neher
@NeBirgitta (Twitter)The Effects of Intermittent Fasting on Brain and Cognitive Function https://t.co/u2aF94jgnx
view full postFebruary 29, 2024
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Sandra minguez
@Sandraming68789 (Twitter)3. Puede prevenir el desarrollo de enfermedades neurológicas https://t.co/JPSCVsmRBC #intermittentfasting #Neurology
view full postDecember 12, 2023
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DrRPalmquist
@DrPalmquist (Twitter)The Effects of Intermittent Fasting on Brain and Cognitive Function https://t.co/tmFVxSxGxc
view full postDecember 6, 2023
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G K Y
@_gopiy (Twitter)https://t.co/tax3XaIc84 #IntermittentFasting #ADHD #ASD https://t.co/oFAhJOvT7D
view full postMay 14, 2023
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Artemisa
@Artha_misa (Twitter)@ghunter_frager Y más https://t.co/VSCjspQ8B8
view full postNovember 14, 2022
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Startup
@StartupSanatana (Twitter)@hamsanandi The Effects of Intermittent Fasting on Brain and Cognitive Function https://t.co/jw1NGD4yl8
view full postOctober 26, 2022
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manvir singh
@mnvrsngh (Twitter)References: - https://t.co/MuSLhJS7AK… - https://t.co/jQuFRm9bmZ… - https://t.co/aEgG10FiLA… - https://t.co/fgUQakpeTm
view full postAugust 10, 2022
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Alejandro Arias
@TulipanTricolor (Twitter)RT @mirjam_bloem: Het resultaat van Jips werk in de werkplaats van @UniversiteitNL
view full postMay 18, 2022
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Mirjam Bloemendaal
@mirjam_bloem (Twitter)Het resultaat van Jips werk in de werkplaats van @UniversiteitNL
view full postMay 17, 2022
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Zöhre Kanar
@KanarZohre (Twitter)RT @UzunDr: Çalışmalarda süreli açlığın beyin üzerindeki olumlu etkileri ve bazı beyin patolojilerinde iyileşme sağlayabilecegi gösterilmiş…
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Eda
@bnoktaeda (Twitter)RT @UzunDr: Çalışmalarda süreli açlığın beyin üzerindeki olumlu etkileri ve bazı beyin patolojilerinde iyileşme sağlayabilecegi gösterilmiş…
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ϜϓſϞ
@oyuncak_dunya_ (Twitter)RT @UzunDr: Çalışmalarda süreli açlığın beyin üzerindeki olumlu etkileri ve bazı beyin patolojilerinde iyileşme sağlayabilecegi gösterilmiş…
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adilce bir yaşam sürmek
@harunar87731903 (Twitter)RT @UzunDr: Çalışmalarda süreli açlığın beyin üzerindeki olumlu etkileri ve bazı beyin patolojilerinde iyileşme sağlayabilecegi gösterilmiş…
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Şimşek Çakar
@yldrmztrk8 (Twitter)https://t.co/LhMypQq0IG
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Şimşek Çakar
@yldrmztrk8 (Twitter)RT @UzunDr: Çalışmalarda süreli açlığın beyin üzerindeki olumlu etkileri ve bazı beyin patolojilerinde iyileşme sağlayabilecegi gösterilmiş…
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Kedilere Fısıldayan Kadın
@sour1881 (Twitter)RT @UzunDr: Çalışmalarda süreli açlığın beyin üzerindeki olumlu etkileri ve bazı beyin patolojilerinde iyileşme sağlayabilecegi gösterilmiş…
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Hulin...
@Rukiyestn7 (Twitter)RT @UzunDr: Çalışmalarda süreli açlığın beyin üzerindeki olumlu etkileri ve bazı beyin patolojilerinde iyileşme sağlayabilecegi gösterilmiş…
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Doç. Dr. Işıl
@IsilDr22 (Twitter)Çalışmalarda süreli açlığın beyin üzerindeki olumlu etkileri ve bazı beyin patolojilerinde iyileşme sağlayabilecegi gösterilmiş ancak burada bahsedilen bunun ötesinde.Bedensel girdilerin azalması+ https://t.co/dUMgZFsXnQ
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Mirjam Bloemendaal
@mirjam_bloem (Twitter)@nieuwenhuijze @EditieNL @RTLnieuws Door periodiek vasten kom je ketose door de afwezigheid van eten/koolhydraten als bron van energie. Zie ons review hierover: https://t.co/Cku3oPm9JL
view full postFebruary 1, 2022
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SorenCS
@SorenCS1 (Twitter)RT @agingdoc1: The Effects of Intermittent Fasting on Brain and Cognitive Function https://t.co/UINCJudGGq
view full postNovember 16, 2021
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The Phoenix Lab
@The_Phoenix_Lab (Twitter)RT @agingdoc1: The Effects of Intermittent Fasting on Brain and Cognitive Function https://t.co/UINCJudGGq
view full postNovember 16, 2021
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Agingdoc
@agingdoc1 (Twitter)The Effects of Intermittent Fasting on Brain and Cognitive Function https://t.co/UINCJudGGq
view full postNovember 16, 2021
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Peter Dingle (PhD)
@drdingle (Twitter)The Effects of Intermittent Fasting on Brain and Cognitive Function https://t.co/TM84tE3Uut #mdpinutrients via @Nutrients_MDPI
view full postOctober 22, 2021
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#Autism
@Autism_Journal (Twitter)The Effects of Intermittent Fasting on Brain and Cognitive Function https://t.co/ODTwKa9H9i #PubMed #Autism
view full postSeptember 29, 2021
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Chris Trejbal, CNP, NNCP, PTS, RNT
@TrejbalChris (Twitter)The Effects of Intermittent Fasting on Brain and Cognitive Function https://t.co/TLgXdLyAzk
view full postSeptember 17, 2021
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湘南なぎさクラブ*パーキンソン病患者家族会
@ShonanNagisaC (Twitter)断食が脳・認知機能に及ぼす影響について 「断食パターン、総カロリー摂取量、および特定の栄養素の摂取量の違いが、IF(間欠的断食)の成功に関連する要素である可能性。長期的な研究と無作為化臨床試験によって脳関連疾患の発症と進展に対するIFの長期的な効果」 nutrients https://t.co/6OY7sg0spo
view full postSeptember 15, 2021
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Lieneke Janssen
@lkjanssen (Twitter)RT @mirjam_bloem: out now: our review on the effects of intermittent fasting on brain and cognitive functioning
view full postSeptember 14, 2021
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Wanda Zarzycka
@WandaZarzycka (Twitter)RT @mirjam_bloem: out now: our review on the effects of intermittent fasting on brain and cognitive functioning
view full postSeptember 14, 2021
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Marcus Böhme
@BoehmeMarcus (Twitter)RT @mirjam_bloem: out now: our review on the effects of intermittent fasting on brain and cognitive functioning
view full postSeptember 14, 2021
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Isabella Wagner
@isabellawagnr (Twitter)RT @mirjam_bloem: out now: our review on the effects of intermittent fasting on brain and cognitive functioning
view full postSeptember 14, 2021
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Mirjam Bloemendaal
@mirjam_bloem (Twitter)out now: our review on the effects of intermittent fasting on brain and cognitive functioning
view full postSeptember 14, 2021
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emerson florez
@laniga771209 (Twitter)RT @heniek_htw: The Effects of Intermittent Fasting on Brain and Cognitive Function ➡️ We do so by summarizing the effects of IF which thr…
view full postSeptember 11, 2021
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plantbhai - 3bdu Al-Hakim
@HakimBGZ (Twitter)RT @heniek_htw: The Effects of Intermittent Fasting on Brain and Cognitive Function ➡️ We do so by summarizing the effects of IF which thr…
view full postSeptember 10, 2021
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Frederic Danel
@Frederic_Danel (Twitter)RT @heniek_htw:
view full postSeptember 10, 2021
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Andres Felipe
@Anferupu (Twitter)RT @heniek_htw: The Effects of Intermittent Fasting on Brain and Cognitive Function ➡️ We do so by summarizing the effects of IF which thr…
view full postSeptember 10, 2021
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Oscar Andres
@OscarAndresMD (Twitter)RT @heniek_htw: The Effects of Intermittent Fasting on Brain and Cognitive Function ➡️ We do so by summarizing the effects of IF which thr…
view full postSeptember 10, 2021
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Constanza G. ☀️⚡️
@constanzag77 (Twitter)RT @heniek_htw: The Effects of Intermittent Fasting on Brain and Cognitive Function ➡️ We do so by summarizing the effects of IF which thr…
view full postSeptember 10, 2021
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htw
@heniek_htw (Twitter)September 10, 2021
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htw
@heniek_htw (Twitter)The Effects of Intermittent Fasting on Brain and Cognitive Function ➡️ We do so by summarizing the effects of IF which through metabolic, cellular, and circadian mechanisms lead to anatomical and functional changes in the brain. https://t.co/TollZ0tsBF
view full postSeptember 10, 2021
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Preprints.org
@Preprints_org (Twitter)The Effects of Intermittent Fasting on Brain and Cognitive Function https://t.co/S9o3ybIeGR #MedPreprints #PharmaPreprints #PreprintsOrg @TulipanTricolor @mirjam_bloem
view full postAugust 27, 2021
Abstract Synopsis
- Intermittent fasting (IF), which involves alternating periods of calorie restriction with normal eating, shows promising neurobiological benefits in animal studies, potentially influencing brain health through metabolic, cellular, and circadian mechanisms.
- Current clinical evidence indicates that IF can improve symptoms and disease progression in conditions like epilepsy, Alzheimer’s, and multiple sclerosis, while animal research suggests possible benefits for diseases such as Parkinson’s, stroke, autism, and mood disorders.
- Future research needs to clarify if IF benefits are consistent regardless of age or obesity, and should focus on long-term impacts, variations in fasting protocols, nutrient intake, and conducting more rigorous studies like randomized controlled trials.]

bioRxiv Neuroscience
@biorxiv-neursci.bsky.social (Bluesky)