The discussions praise the study for its large dataset and novel insights into disruptor taxa and oral microbiota, using enthusiastic phrases like 'game-changing' and 'highlighting' that reflect strong interest and perceived importance. Words like 'largest dataset' and references to specific bacterial roles indicate deep engagement, while comments about the potential for better understanding gastrointestinal disorders underscore the high impact of this research.
AgreementStrong agreement
Most discussions strongly endorse the findings, highlighting the significance of the study in understanding gut microbiota and its health implications.
InterestHigh interest
Posts demonstrate high curiosity about the dataset and its implications, emphasizing terms like 'largest dataset' and 'pivotal role' which indicate active engagement.
EngagementHigh engagement
Discussions reference specific concepts such as disruptor taxa, bacterial diversity, and SIBO, showing deep understanding and thoughtful reactions.
ImpactHigh impact
Numerous comments underline the importance of this research for GI health and potential clinical applications, emphasizing its high impact.
Abstract in brief
Quantitative sequencing reveals that certain oral microbes, especially disruptor taxa like Klebsiella and Escherichia, are present in the human duodenum and may displace beneficial anaerobes, particularly in individuals with small intestinal bacterial overgrowth (SIBO).
The study highlights that higher total microbial loads and the presence of disruptor taxa are linked to more severe gastrointestinal symptoms, emphasizing the importance of measuring absolute microbial abundance to understand small intestine health.
This research is the largest to date on duodenal microbiota, demonstrating a significant connection between oral and small intestinal microbiomes and their potential impact on gastrointestinal disorders.]
#SIBO: moving from pure number of microbes ▶️ dysbiosis.
“High total microbial load alone in the small intestine was not associated with GI symptoms usually observed in subjects with SIBO and other GI conditions and diseases.”
#GITwitter #microbiome
https://t.co/mFFEoWdqnP
Nov 4, 2021 · 27 likes · 5 shares · 24,128 followersView post →
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GutMicrobiota Health
@GMFHx · X
Upper gastrointestinal disorders and abdominal pain afflict 30% of the population. @RuchiMathurMD, @MarkPimentelMD & colleagues from @MASTprogram and Caltech suggest a link between the absolute abundance of disruptor taxa, SIBO and severe GI symptoms https://t.co/eFnNBKaKPB https://t.co/Y0wYjHNU3q
Nov 11, 2021 · 22 likes · 7 shares · 35,571 followersView post →
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Ali Rezaie MD MSc
@AliRezaieMD · X
Our recent paper on the pivotal role of "anarchist bacteria" (disruptor taxa) in #microbiome balance. Aerobic disruptor taxa displace strict anaerobes and decrease bacterial diversity in the small bowel!
Nov 4, 2021 · 20 likes · 6 shares · 5,136 followersView post →
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Microbiome
@MicrobiomeJ · X
Quantitative sequencing clarifies the role of disruptor taxa, oral microbiota, and strict anaerobes in the human small-intestine microbiome https://t.co/UAqRZJye9R
Nov 2, 2021 · 10 likes · 2 shares · 20,507 followersView post →
RM
Ruchi Mathur MD
@RuchiMathurMD · X
Congrats to our @MASTprogram and colleagues at Caltech on this publication in Microbiome! This study provides the largest dataset of the absolute abundance of microbiota from the human duodenum to date! Take a look!! https://t.co/etTOr2XKqZ
Nov 4, 2021 · 8 likes · 2 shares · 1,696 followersView post →
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ismagilovlab
@ismagilovlab · X
Largest dataset of the absolute abundance of microbiota from the human duodenum to date! We found a clear relationship between oral and SI microbiota, and evidence for an association between absolute abundance of disruptor taxa, SIBO, and GI symptoms.
https://t.co/o89maCLeDR
Nov 22, 2021 · 3 likes · 2 shares · 138 followersView post →
The mouth is the gateway to the gut. Good oral health is essential for maintaining a healthy gut environment by promoting beneficial microbes and preventing harmful ones from establishing.
Quantitative sequencing reveals the presence of oral microbes, particularly disruptor taxa like Klebsiella and Escherichia, in the human duodenum, and their potential to displace beneficial anaerobes, especially in SIBO…
Largest dataset of the absolute abundance of microbiota from the human duodenum to date! We found a clear relationship between oral and SI microbiota, and evidence for an association between absolute abundance of disruptor taxa, SIBO, and GI symptoms.
https://t.co/o89maCLeDR
Nov 22, 2021 · 3 likes · 2 shares · 138 followersView post →
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Pam Emmer
@lifeaftersibo · X
RT @GMFHx: Upper gastrointestinal disorders and abdominal pain afflict 30% of the population. @RuchiMathurMD, @MarkPimentelMD & colleagues…
Nov 11, 2021 · 7 shares · 830 followersView post →
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MAST Research Program
@MASTprogram · X
RT @GMFHx: Upper gastrointestinal disorders and abdominal pain afflict 30% of the population. @RuchiMathurMD, @MarkPimentelMD & colleagues…
Nov 11, 2021 · 7 shares · 3,139 followersView post →
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Vibrant Labs
@VibrantLabs1 · X
RT @GMFHx: Upper gastrointestinal disorders and abdominal pain afflict 30% of the population. @RuchiMathurMD, @MarkPimentelMD & colleagues…
Nov 11, 2021 · 7 shares · 137 followersView post →
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fausto heredia z.
@drfherediaz · X
RT @GMFHx: Upper gastrointestinal disorders and abdominal pain afflict 30% of the population. @RuchiMathurMD, @MarkPimentelMD & colleagues…
Nov 11, 2021 · 7 shares · 4,445 followersView post →
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Pau Oller
@PauOller · X
RT @GMFHx: Upper gastrointestinal disorders and abdominal pain afflict 30% of the population. @RuchiMathurMD, @MarkPimentelMD & colleagues…
Nov 11, 2021 · 7 shares · 7,398 followersView post →
GH
GutMicrobiota Health
@GMFHx · X
Upper gastrointestinal disorders and abdominal pain afflict 30% of the population. @RuchiMathurMD, @MarkPimentelMD & colleagues from @MASTprogram and Caltech suggest a link between the absolute abundance of disruptor taxa, SIBO and severe GI symptoms https://t.co/eFnNBKaKPB https://t.co/Y0wYjHNU3q
Nov 11, 2021 · 22 likes · 7 shares · 35,571 followersView post →
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Robin Berlin RDN
@robinberlinrd · X
RT @RuchiMathurMD: Congrats to our @MASTprogram and colleagues at Caltech on this publication in Microbiome! This study provides the larg…
Nov 5, 2021 · 2 shares · 1,149 followersView post →
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Gabriela Leite, PhD
@GabrielaGSLeite · X
RT @AliRezaieMD: Our recent paper on the pivotal role of "anarchist bacteria" (disruptor taxa) in #microbiome balance. Aerobic disruptor t…
RT @AliRezaieMD: Our recent paper on the pivotal role of "anarchist bacteria" (disruptor taxa) in #microbiome balance. Aerobic disruptor t…
Nov 4, 2021 · 6 shares · 4,480 followersView post →
DK
Dr. M. Azzam Kayasseh
@drmakclinic · X
RT @AliRezaieMD: Our recent paper on the pivotal role of "anarchist bacteria" (disruptor taxa) in #microbiome balance. Aerobic disruptor t…
Nov 4, 2021 · 6 shares · 2,715 followersView post →
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Chase P. Kelley
@chasepkelley · X
Fantastic work from Jacob Barlow, @GabrielaGSLeite and @ismagilovlab on using quantitative sequencing to study the duodenum microbiome, identifying disruptor taxa and illuminating an association between bacterial composition and SIBO. https://t.co/CTdA7i9dvL
RT @john_damianosMD: #SIBO: moving from pure number of microbes ▶️ dysbiosis.
“High total microbial load alone in the small intestine was…
Nov 4, 2021 · 5 shares · 12,432 followersView post →
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Shima Ghavimi
@ShimaghavimiMD · X
RT @john_damianosMD: #SIBO: moving from pure number of microbes ▶️ dysbiosis.
“High total microbial load alone in the small intestine was…
Nov 4, 2021 · 5 shares · 4,480 followersView post →
JD
John Damianos, M.D.
@john_damianosMD · X
#SIBO: moving from pure number of microbes ▶️ dysbiosis.
“High total microbial load alone in the small intestine was not associated with GI symptoms usually observed in subjects with SIBO and other GI conditions and diseases.”
#GITwitter #microbiome
https://t.co/mFFEoWdqnP
Nov 4, 2021 · 27 likes · 5 shares · 24,128 followersView post →
EF
Emma Fogt
@emmafogt · X
RT @AliRezaieMD: Our recent paper on the pivotal role of "anarchist bacteria" (disruptor taxa) in #microbiome balance. Aerobic disruptor t…
Nov 4, 2021 · 6 shares · 1,458 followersView post →
MP
MAST Research Program
@MASTprogram · X
RT @AliRezaieMD: Our recent paper on the pivotal role of "anarchist bacteria" (disruptor taxa) in #microbiome balance. Aerobic disruptor t…
Nov 4, 2021 · 6 shares · 3,139 followersView post →
AM
Ali Rezaie MD MSc
@AliRezaieMD · X
Our recent paper on the pivotal role of "anarchist bacteria" (disruptor taxa) in #microbiome balance. Aerobic disruptor taxa displace strict anaerobes and decrease bacterial diversity in the small bowel!
Nov 4, 2021 · 20 likes · 6 shares · 5,136 followersView post →
MP
MAST Research Program
@MASTprogram · X
RT @RuchiMathurMD: Congrats to our @MASTprogram and colleagues at Caltech on this publication in Microbiome! This study provides the larg…
Nov 4, 2021 · 2 shares · 3,139 followersView post →
RM
Ruchi Mathur MD
@RuchiMathurMD · X
Congrats to our @MASTprogram and colleagues at Caltech on this publication in Microbiome! This study provides the largest dataset of the absolute abundance of microbiota from the human duodenum to date! Take a look!! https://t.co/etTOr2XKqZ
Nov 4, 2021 · 8 likes · 2 shares · 1,696 followersView post →
SM
Stacy B.Mcclain
@mcclain_stay · X
RT @MicrobiomeJ: Quantitative sequencing clarifies the role of disruptor taxa, oral microbiota, and strict anaerobes in the human small-int…
RT @MicrobiomeJ: Quantitative sequencing clarifies the role of disruptor taxa, oral microbiota, and strict anaerobes in the human small-int…
Nov 2, 2021 · 2 shares · 1,274 followersView post →
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Microbiome
@MicrobiomeJ · X
Quantitative sequencing clarifies the role of disruptor taxa, oral microbiota, and strict anaerobes in the human small-intestine microbiome https://t.co/UAqRZJye9R
Nov 2, 2021 · 10 likes · 2 shares · 20,507 followersView post →
SP
Symbiosis papers
@Symbiosispapers · X
Quantitative sequencing clarifies the role of disruptor taxa, oral microbiota, and strict anaerobes in the human small-intestine microbiome https://t.co/uxhGcKcI5U
Quantitative sequencing clarifies the role of disruptor taxa, oral microbiota, and strict anaerobes in the human small-intestine microbiome https://t.co/DOmXeAe9G2 https://t.co/oYk0ix3IEu
Microbiota Oral e Intestinal | PDF | Gastrointestinal Tract | Microbiota
News
doi: 10.1186/ Engevik, M. A., Danhof, H. A., Auchtung, J., Endres, B. T., Ruan, W., Basseres, E., et al. s40168-021-01162-2 (2021a). Fusobacteriumnucleatum ...
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