Brain Responses to Propofol in Advance of Recovery from Coma and Disorders of Consciousness: A Preliminary Study.

Catherine Duclos, Charlotte Maschke, Yacine Mahdid, Danielle Nadin, Alexander Rokos, Caroline Arbour, Mohamed Badawy, Justin Létourneau, Adrian M Owen, Gilles Plourde, Stefanie Blain-Moraes

January 2022 Am J Respir Crit Care Med

Synopsis of Social media discussions

Throughout the discussions, participants demonstrate strong interest and engagement, with comments highlighting the innovative use of propofol to assess brain reconfiguration and predict recovery. Words like 'blown away,' 'fascinating,' and 'very proud' reflect excitement and respect for the research's novelty and significance, underscoring its perceived high impact on both clinical practices and future research.

A
Agreement
 Strong agreement

Most discussions express strong support and excitement about the potential uses of propofol in understanding and predicting coma recovery, evidenced by phrases like 'blown away,' 'very proud,' and 'fascinating study.'

I
Interest
 High level of interest

The posts show high curiosity, focusing on innovative methods and significant clinical implications, with repeated references to the 'adaptive reconfiguration index' and the new predictive approach.

E
Engagement
 High engagement

Many responses delve into the scientific and clinical details, referencing EEG measures, brain network reorganization, and prognostic importance, indicating deep engagement with the research findings.

I
Impact
 High level of impact

Several discussions highlight the high potential impact, mentioning breakthroughs that could improve clinical decision-making and prognosis for brain-injured patients, emphasizing words like 'broad implications' and 'game changer.'

Social Mentions

YouTube

2 Videos

Twitter

26 Posts

News

3 Articles

Metrics

Video Views

45,788

Total Likes

194

Extended Reach

132,101

Social Features

31

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

Predicting Consciousness Recovery Using Brain Responses to Propofol

Predicting Consciousness Recovery Using Brain Responses to Propofol

Brain responses to propofol can predict recovery from coma and disorders of consciousness, using a new adaptive reconfiguration index measuring EEG changes to assess patient prognosis.

McGill University

November 24, 2021

43,611 views

Predicting Coma Recovery Using EEG and Propofol Response Analysis

Predicting Coma Recovery Using EEG and Propofol Response Analysis

This study explores how brain responses to propofol can predict recovery of consciousness in brain-injured patients, highlighting an adaptive reconfiguration index based on EEG patterns to distinguish those who recover from coma.

McGill University

November 24, 2021

2,177 views

  • Curious_Seeker,MD
    @md_seeker (Twitter)

    RT @rkchoi: Blown away by this pilot trial that uses propofol to assess brain reorganization ability and thus ability to eventually regain…
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    February 14, 2022

    2

  • Richard Choi, DO, FNCS
    @rkchoi (Twitter)

    Blown away by this pilot trial that uses propofol to assess brain reorganization ability and thus ability to eventually regain consciousness. Could have very broad implications in prognostication. We need > like this to prognosticate #tbi #neuroICU https://t.co/pYAn75jCDs
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    February 14, 2022

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  • Sasha Yakhkind
    @sashkind (Twitter)

    @stephanamayer @CuringComa Another potentially cool way to look at coma recovery: https://t.co/6kmc2WgFdo
    view full post

    January 30, 2022

    1

  • Dawn P
    @finniganandme (Twitter)

    RT @CatherineDuclo6: What happens when you anesthetize an individual that’s already unconscious? Can the unconscious brain’s reaction to an…
    view full post

    January 23, 2022

    7

  • Paul E. Dux
    @PaulEDux (Twitter)

    RT @CatherineDuclo6: What happens when you anesthetize an individual that’s already unconscious? Can the unconscious brain’s reaction to an…
    view full post

    January 22, 2022

    7

  • Dominika Radziun
    @nikaradziun (Twitter)

    RT @CatherineDuclo6: What happens when you anesthetize an individual that’s already unconscious? Can the unconscious brain’s reaction to an…
    view full post

    January 22, 2022

    7

  • Tristan Bekinschtein
    @TrikBek (Twitter)

    RT @CatherineDuclo6: What happens when you anesthetize an individual that’s already unconscious? Can the unconscious brain’s reaction to an…
    view full post

    January 22, 2022

    7

  • Daniel Rodger
    @philosowhal (Twitter)

    Fascinating study! https://t.co/0LAc0eSgM8
    view full post

    January 22, 2022

  • Neil Kazimierz Sheridan 尼尔
    @KoalasWelcome (Twitter)

    RT @CatherineDuclo6: What happens when you anesthetize an individual that’s already unconscious? Can the unconscious brain’s reaction to an…
    view full post

    January 22, 2022

    7

  • Prof. Adrian M. Owen OBE, FRS
    @Comadork (Twitter)

    RT @CatherineDuclo6: What happens when you anesthetize an individual that’s already unconscious? Can the unconscious brain’s reaction to an…
    view full post

    January 22, 2022

    7

  • Stefanie Blain-Moraes
    @BlainMoraes (Twitter)

    RT @CatherineDuclo6: What happens when you anesthetize an individual that’s already unconscious? Can the unconscious brain’s reaction to an…
    view full post

    January 21, 2022

    7

  • Catherine_Duclos
    @CatherineDuclo6 (Twitter)

    What happens when you anesthetize an individual that’s already unconscious? Can the unconscious brain’s reaction to anesthesia confirm the presence of some underlying capacity for consciousness? Here's our answer: https://t.co/s4rl6sNTYy
    view full post

    January 21, 2022

    28

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  • ATS Blue Journal
    @ATSBlueEditor (Twitter)

    Brain Responses to Propofol in Advance of Recovery from Coma and Disorders of Consciousness: A Preliminary Study
    view full post

    January 18, 2022

    4

  • McGill Physical & Occupational Therapy
    @McGillRehab (Twitter)

    RT @BlainMoraes: Very proud of my lab’s article published today in the American Journal of Respiratory and Critical Care Medicine. In this…
    view full post

    January 16, 2022

    2

  • Danielle
    @DanielleSipsTea (Twitter)

    RT @BlainMoraes: Very proud of my lab’s article published today in the American Journal of Respiratory and Critical Care Medicine. In this…
    view full post

    January 15, 2022

    2

  • Stefanie Blain-Moraes
    @BlainMoraes (Twitter)

    Very proud of my lab’s article published today in the American Journal of Respiratory and Critical Care Medicine. In this preliminary study, we show that anesthesia can be used as a tool to accurately predict recovery from a disorder of consciousness. https://t.co/jWINpYj7gK https://t.co/7GY9Vg5rHd
    view full post

    January 15, 2022

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  • Michele Introna
    @MichiIntrona (Twitter)

    RT @cu_bas: Wow https://t.co/AHV6UVEt03 Prognostication of #consciousness recovery
    view full post

    January 15, 2022

    1

  • Luca Bastia
    @cu_bas (Twitter)

    Wow https://t.co/AHV6UVEt03 Prognostication of #consciousness recovery
    view full post

    January 15, 2022

    2

    1

  • @SoMe4MV
    @some4mv (Twitter)

    RT @some4mv: Brain Responses to Propofol in Advance of Recovery from Coma and Disorders of Consciousness: A Preliminary Study https://t.co/z1LCqWdqNG #SoMe4MV from @ATSBlueEditor
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    January 15, 2022

  • @SoMe4MV
    @some4mv (Twitter)

    RT @some4mv: Brain Responses to Propofol in Advance of Recovery from Coma and Disorders of Consciousness: A Preliminary Study https://t.co/z1LCqWdqNG #SoMe4MV from @ATSBlueEditor
    view full post

    January 14, 2022

    2

  • @SoMe4MV
    @some4mv (Twitter)

    Brain Responses to Propofol in Advance of Recovery from Coma and Disorders of Consciousness: A Preliminary Study https://t.co/z1LCqWdqNG #SoMe4MV from @ATSBlueEditor
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    January 14, 2022

  • Dr Damm
    @DrDamm (Twitter)

    RT @SCCMPresident: Administration of propofol induces brain network reconfiguration that allows EEG to measure "adaptive reconfiguration in…
    view full post

    November 23, 2021

    2

  • Greg Martin
    @gsmartinmd (Twitter)

    RT @SCCMPresident: Administration of propofol induces brain network reconfiguration that allows EEG to measure "adaptive reconfiguration in…
    view full post

    November 22, 2021

    2

  • Jose L. Pascual, MD, PhD, FRCS(C), FACS, FCCM
    @SCCMPresident (Twitter)

    Administration of propofol induces brain network reconfiguration that allows EEG to measure "adaptive reconfiguration index" that predicts whether someone will recover from acute brain injury https://t.co/LIphswv4sk
    view full post

    November 20, 2021

    5

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  • Sarah C. Marshall
    @PhysioSarahPT (Twitter)

    RT @McGillRehab: New from #McGillSPOT Duclos, Maschke, Mahdid, Nadin, Rokos, & Blain-Moraes "Brain Responses to Propofol in Advance of Reco…
    view full post

    November 15, 2021

    1

  • McGill Physical & Occupational Therapy
    @McGillRehab (Twitter)

    New from #McGillSPOT Duclos, Maschke, Mahdid, Nadin, Rokos, & Blain-Moraes "Brain Responses to Propofol in Advance of Recovery From Coma and Disorders of Consciousness: A Preliminary Study" https://t.co/uyPwT0PzwQ
    view full post

    November 15, 2021

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Abstract Synopsis

  • Predicting recovery of consciousness in brain-injured patients is vital for clinical decision-making and may be assessed using the effects of propofol on brain networks.
  • Researchers developed an "adaptive reconfiguration index" to measure changes in EEG patterns before, during, and after propofol administration in patients with disorders of consciousness.
  • The index showed a significant difference between patients who later recovered consciousness and those who remained unresponsive, indicating its potential as a reliable tool for predicting consciousness recovery in clinical settings.