Am J Respir Crit Care Med January 2022 PMID 34748722

Brain Responses to Propofol in Advance of Recovery from Coma and Disorders of Consciousness: A Preliminary Study.

Catherine Duclos, Charlotte Maschke, Yacine Mahdid, Danielle Nadin, Alexander Rokos, Caroline Arbour, Mohamed Badawy, Justin Létourneau, Adrian M Owen, Gilles Plourde, Stefanie Blain-Moraes

Mentions

31
Peak: 19 in Jan 2022
across 3 sources since Nov 2021

Extended reach

132,101
potential audience

Total likes

194

Video views

45,788

Mentions per month

Nov 2021 – Feb 2022

Where it's discussed

  • X / Twitter26 posts
  • News3 articles
  • YouTube2 videos

AI synopsis

What people are saying

Throughout the discussions, participants demonstrate strong interest and engagement, with comments highlighting the innovative use of propofol to assess brain reconfiguration and predict recovery. Words like 'blown away,' 'fascinating,' and 'very proud' reflect excitement and respect for the research's novelty and significance, underscoring its perceived high impact on both clinical practices and future research.

AgreementStrong agreement

Most discussions express strong support and excitement about the potential uses of propofol in understanding and predicting coma recovery, evidenced by phrases like 'blown away,' 'very proud,' and 'fascinating study.'

InterestHigh interest

The posts show high curiosity, focusing on innovative methods and significant clinical implications, with repeated references to the 'adaptive reconfiguration index' and the new predictive approach.

EngagementHigh engagement

Many responses delve into the scientific and clinical details, referencing EEG measures, brain network reorganization, and prognostic importance, indicating deep engagement with the research findings.

ImpactHigh impact

Several discussions highlight the high potential impact, mentioning breakthroughs that could improve clinical decision-making and prognosis for brain-injured patients, emphasizing words like 'broad implications' and 'game changer.'

Abstract in brief

  • Predicting recovery of consciousness in brain-injured patients is vital for clinical decision-making and may be assessed using the effects of propofol on brain networks.
  • Researchers developed an "adaptive reconfiguration index" to measure changes in EEG patterns before, during, and after propofol administration in patients with disorders of consciousness.
  • The index showed a significant difference between patients who later recovered consciousness and those who remained unresponsive, indicating its potential as a reliable tool for predicting consciousness recovery in clinical settings.

Top posts

Most liked on X and Bluesky
Catherine_Duclos
@CatherineDuclo6 · X

What happens when you anesthetize an individual that’s already unconscious? Can the unconscious brain’s reaction to anesthesia confirm the presence of some underlying capacity for consciousness? Here's our answer: https://t.co/s4rl6sNTYy

Jan 21, 2022 · 28 likes · 7 shares · 134 followers View post →
Stefanie Blain-Moraes
@BlainMoraes · X

Very proud of my lab’s article published today in the American Journal of Respiratory and Critical Care Medicine. In this preliminary study, we show that anesthesia can be used as a tool to accurately predict recovery from a disorder of consciousness. https://t.co/jWINpYj7gK https://t.co/7GY9Vg5rHd

Jan 15, 2022 · 13 likes · 2 shares · 254 followers View post →
Richard Choi, DO, FNCS
@rkchoi · X

Blown away by this pilot trial that uses propofol to assess brain reorganization ability and thus ability to eventually regain consciousness. Could have very broad implications in prognostication. We need > like this to prognosticate #tbi #neuroICU https://t.co/pYAn75jCDs

Feb 14, 2022 · 9 likes · 2 shares · 3,793 followers View post →
Jose L. Pascual, MD, PhD, FRCS(C), FACS, FCCM
@SCCMPresident · X

Administration of propofol induces brain network reconfiguration that allows EEG to measure "adaptive reconfiguration index" that predicts whether someone will recover from acute brain injury https://t.co/LIphswv4sk

Nov 20, 2021 · 5 likes · 2 shares · 12,604 followers View post →
ATS Blue Journal
@ATSBlueEditor · X

Brain Responses to Propofol in Advance of Recovery from Coma and Disorders of Consciousness: A Preliminary Study

Jan 18, 2022 · 4 likes · 20,059 followers View post →
McGill Physical & Occupational Therapy
@McGillRehab · X

New from #McGillSPOT Duclos, Maschke, Mahdid, Nadin, Rokos, & Blain-Moraes "Brain Responses to Propofol in Advance of Recovery From Coma and Disorders of Consciousness: A Preliminary Study" https://t.co/uyPwT0PzwQ

Nov 15, 2021 · 3 likes · 1 share · 1,758 followers View post →

All mentions

Curious_Seeker,MD
@md_seeker · X

RT @rkchoi: Blown away by this pilot trial that uses propofol to assess brain reorganization ability and thus ability to eventually regain…

Feb 14, 2022 · 2 shares · 118 followers View post →
Richard Choi, DO, FNCS
@rkchoi · X

Blown away by this pilot trial that uses propofol to assess brain reorganization ability and thus ability to eventually regain consciousness. Could have very broad implications in prognostication. We need > like this to prognosticate #tbi #neuroICU https://t.co/pYAn75jCDs

Feb 14, 2022 · 9 likes · 2 shares · 3,793 followers View post →
Sasha Yakhkind
@sashkind · X

@stephanamayer @CuringComa Another potentially cool way to look at coma recovery: https://t.co/6kmc2WgFdo

Jan 30, 2022 · 1 like · 407 followers View post →
Dawn P
@finniganandme · X

RT @CatherineDuclo6: What happens when you anesthetize an individual that’s already unconscious? Can the unconscious brain’s reaction to an…

Jan 23, 2022 · 7 shares · 97 followers View post →
Paul E. Dux
@PaulEDux · X

RT @CatherineDuclo6: What happens when you anesthetize an individual that’s already unconscious? Can the unconscious brain’s reaction to an…

Jan 22, 2022 · 7 shares · 1,410 followers View post →
Dominika Radziun
@nikaradziun · X

RT @CatherineDuclo6: What happens when you anesthetize an individual that’s already unconscious? Can the unconscious brain’s reaction to an…

Jan 22, 2022 · 7 shares · 1,869 followers View post →
Tristan Bekinschtein
@TrikBek · X

RT @CatherineDuclo6: What happens when you anesthetize an individual that’s already unconscious? Can the unconscious brain’s reaction to an…

Jan 22, 2022 · 7 shares · 3,660 followers View post →
Daniel Rodger
@philosowhal · X

Fascinating study! https://t.co/0LAc0eSgM8

Jan 22, 2022 · 573 followers View post →
Neil Kazimierz Sheridan 尼尔
@KoalasWelcome · X

RT @CatherineDuclo6: What happens when you anesthetize an individual that’s already unconscious? Can the unconscious brain’s reaction to an…

Jan 22, 2022 · 7 shares · 2,326 followers View post →
Prof. Adrian M. Owen OBE, FRS
@Comadork · X

RT @CatherineDuclo6: What happens when you anesthetize an individual that’s already unconscious? Can the unconscious brain’s reaction to an…

Jan 22, 2022 · 7 shares · 5,915 followers View post →
Stefanie Blain-Moraes
@BlainMoraes · X

RT @CatherineDuclo6: What happens when you anesthetize an individual that’s already unconscious? Can the unconscious brain’s reaction to an…

Jan 21, 2022 · 7 shares · 254 followers View post →
Catherine_Duclos
@CatherineDuclo6 · X

What happens when you anesthetize an individual that’s already unconscious? Can the unconscious brain’s reaction to anesthesia confirm the presence of some underlying capacity for consciousness? Here's our answer: https://t.co/s4rl6sNTYy

Jan 21, 2022 · 28 likes · 7 shares · 134 followers View post →
ATS Blue Journal
@ATSBlueEditor · X

Brain Responses to Propofol in Advance of Recovery from Coma and Disorders of Consciousness: A Preliminary Study

Jan 18, 2022 · 4 likes · 20,059 followers View post →
McGill Physical & Occupational Therapy
@McGillRehab · X

RT @BlainMoraes: Very proud of my lab’s article published today in the American Journal of Respiratory and Critical Care Medicine. In this…

Jan 16, 2022 · 2 shares · 1,758 followers View post →
Danielle
@DanielleSipsTea · X

RT @BlainMoraes: Very proud of my lab’s article published today in the American Journal of Respiratory and Critical Care Medicine. In this…

Jan 15, 2022 · 2 shares · 2,356 followers View post →
Stefanie Blain-Moraes
@BlainMoraes · X

Very proud of my lab’s article published today in the American Journal of Respiratory and Critical Care Medicine. In this preliminary study, we show that anesthesia can be used as a tool to accurately predict recovery from a disorder of consciousness. https://t.co/jWINpYj7gK https://t.co/7GY9Vg5rHd

Jan 15, 2022 · 13 likes · 2 shares · 254 followers View post →
Michele Introna
@MichiIntrona · X

RT @cu_bas: Wow https://t.co/AHV6UVEt03 Prognostication of #consciousness recovery

Jan 15, 2022 · 1 share · 798 followers View post →
Luca Bastia
@cu_bas · X

Wow https://t.co/AHV6UVEt03 Prognostication of #consciousness recovery

Jan 15, 2022 · 2 likes · 1 share · 196 followers View post →
@SoMe4MV
@some4mv · X

RT @some4mv: Brain Responses to Propofol in Advance of Recovery from Coma and Disorders of Consciousness: A Preliminary Study https://t.co/z1LCqWdqNG #SoMe4MV from @ATSBlueEditor

Jan 15, 2022 · 6,328 followers View post →
@SoMe4MV
@some4mv · X

RT @some4mv: Brain Responses to Propofol in Advance of Recovery from Coma and Disorders of Consciousness: A Preliminary Study https://t.co/z1LCqWdqNG #SoMe4MV from @ATSBlueEditor

Jan 14, 2022 · 2 likes · 6,328 followers View post →
@SoMe4MV
@some4mv · X

Brain Responses to Propofol in Advance of Recovery from Coma and Disorders of Consciousness: A Preliminary Study https://t.co/z1LCqWdqNG #SoMe4MV from @ATSBlueEditor

Jan 14, 2022 · 6,328 followers View post →
Dr Damm
@DrDamm · X

RT @SCCMPresident: Administration of propofol induces brain network reconfiguration that allows EEG to measure "adaptive reconfiguration in…

Nov 23, 2021 · 2 shares · 266 followers View post →
Greg Martin
@gsmartinmd · X

RT @SCCMPresident: Administration of propofol induces brain network reconfiguration that allows EEG to measure "adaptive reconfiguration in…

Nov 22, 2021 · 2 shares · 5,766 followers View post →
Jose L. Pascual, MD, PhD, FRCS(C), FACS, FCCM
@SCCMPresident · X

Administration of propofol induces brain network reconfiguration that allows EEG to measure "adaptive reconfiguration index" that predicts whether someone will recover from acute brain injury https://t.co/LIphswv4sk

Nov 20, 2021 · 5 likes · 2 shares · 12,604 followers View post →
Sarah C. Marshall
@PhysioSarahPT · X

RT @McGillRehab: New from #McGillSPOT Duclos, Maschke, Mahdid, Nadin, Rokos, & Blain-Moraes "Brain Responses to Propofol in Advance of Reco…

Nov 15, 2021 · 1 share · 807 followers View post →
McGill Physical & Occupational Therapy
@McGillRehab · X

New from #McGillSPOT Duclos, Maschke, Mahdid, Nadin, Rokos, & Blain-Moraes "Brain Responses to Propofol in Advance of Recovery From Coma and Disorders of Consciousness: A Preliminary Study" https://t.co/uyPwT0PzwQ

Nov 15, 2021 · 3 likes · 1 share · 1,758 followers View post →