Science December 2021 PMID 34762488

Computed structures of core eukaryotic protein complexes.

Ian R Humphreys, Jimin Pei, Minkyung Baek, Aditya Krishnakumar, Ivan Anishchenko, Sergey Ovchinnikov, Jing Zhang, Travis J Ness, Sudeep Banjade, Saket R Bagde, Viktoriya G Stancheva, Xiao-Han Li, Kaixian Liu, Zhi Zheng, Daniel J Barrero

Mentions

179
Peak: 91 in Nov 2021
across 5 sources since Nov 2021

Extended reach

569,161
potential audience

Total likes

359

Video views

498

Mentions per month

Nov 2021 – Sep 2025

Where it's discussed

  • X / Twitter145 posts
  • News23 articles
  • Blogs6 articles
  • Facebook3 posts
  • YouTube2 videos

AI synopsis

What people are saying

Overall, the social discussions reflect high enthusiasm and support, citing examples such as models of enzyme assemblies, new insights into key cellular processes, and the use of advanced AI techniques. Words like 'exciting', 'mind-blowing', and 'game changer' demonstrate both the excitement and perceived importance of this research, revealing a community deeply engaged with the scientific breakthrough.

AgreementStrong agreement

Most discussions support the significance and innovative nature of the publication, emphasizing advances in structure prediction and biological insights.

InterestHigh interest

Posts express high interest, highlighting breakthroughs in protein modeling and potential applications in biology and medicine.

EngagementHigh engagement

Many discussions reflect deep engagement through mentioning specific methods like AlphaFold and RoseTTAFold and exploring implications for cellular functions.

ImpactHigh impact

The discussions suggest the research could have a transformative impact on understanding protein interactions and cellular machinery, with several recognizing its broad relevance.

Abstract in brief

  • Protein-protein interactions are essential for biological functions, yet many eukaryotic protein complex structures remain unknown, highlighting the need for better identification methods.
  • Using advanced techniques like coevolution analysis and deep-learning models (RoseTTAFold and AlphaFold), researchers screened 8.3 million yeast protein pairs to predict interactions and construct structural models.
  • They identified 1505 potential interacting pairs, characterized 106 previously unknown protein assemblies, and provided insights into 806 complexes not structurally documented, emphasizing their importance in key cellular processes.

Top posts

Most liked on X and Bluesky
SGD Project @yeastgenome@genomic.social (bsky too)
@yeastgenome · X

Exciting @ScienceMagazine paper from David Baker's lab @UWproteindesign describes using deep-learning algorithms #AlphaFold2 and #RoseTTAFold to model 3D structures of protein-protein interactions, including higher order complexes, in #yeast https://t.co/JSsfvbU1FL https://t.co/7gzPUMLEnY

Dec 16, 2021 · 123 likes · 27 shares · 3,423 followers View post →
Emily Leproust
@EmilyLeproust · X

I’m more of a #DNA fan myself, but this is mind blowing work in structure prediction and interaction. @UWproteindesign Computed structures of core eukaryotic protein complexes https://t.co/pf9DGgjDlI

Nov 22, 2021 · 50 likes · 12 shares · 14,162 followers View post →
Manuela Casasoli
@manuelacasasoli · X

"Using #DeepLearning methods to systematically identify and build structures for the protein complexes that mediate key processes in eukaryotes." #Science #proteins #Biology #cells ⏯️Computed structures of core eukaryotic protein complexes https://t.co/v5jMcof4dJ https://t.co/kFHc1F8tgD

Dec 10, 2021 · 45 likes · 6 shares · 11,556 followers View post →
EMBL-EBI
@emblebi · X

Using #AlphaFold to help predict the structures of large protein complexes enabled researchers at @UWproteindesign, @UTSWnews, and colleagues to gain new insights into their vital biological functions. https://t.co/8vktioTbbn https://t.co/1Rz0BM5QYu

Jul 22, 2022 · 21 likes · 4 shares · 73,162 followers View post →
Ohue M/大上雅史
@tonets · X

あ、PPI予測やられたな? Computed structures of core eukaryotic protein complexes https://t.co/QqI4H0WyHn

Nov 12, 2021 · 17 likes · 5 shares · 12,549 followers View post →
NobuoMaita
@nob_mai · X

D. Bakerも複合体予測出してきた Computed structures of core eukaryotic protein complexes https://t.co/GZgmfwR7yf

Nov 11, 2021 · 15 likes · 3 shares · 1,076 followers View post →

All mentions

Ian Humphreys
@IanRHum · X

This effort is the culmination of a series of proteome interaction prediction stories from Ecoli (https://t.co/9Cn55FaGQL), to yeast (https://t.co/DqKtaIrzXw), and human bacterial pathogens (https://t.co/NPKmEJzils)!

Sep 25, 2025 · 4 likes · 540 followers View post →
Shinya Fushinobu
@sugargroove · X

RT @oxkawaka: Computed structures of core eukaryotic protein complexes さぁ、RoseTTAFold と AlphaFoldのコンビで示してやるよ複合体たちの予測をなと言うお話。 https://t.co…

Nov 24, 2022 · 1 share · 4,102 followers View post →
LaatDovahKiin.eth | Posiedon.eth
@Keeksmyhero · X

RT @emblebi: Using #AlphaFold to help predict the structures of large protein complexes enabled researchers at @UWproteindesign, @UTSWnews,…

Jul 23, 2022 · 4 shares · 212 followers View post →
Saubashya Sur, PhD
@SaubashyaSur · X

RT @emblebi: Using #AlphaFold to help predict the structures of large protein complexes enabled researchers at @UWproteindesign, @UTSWnews,…

Jul 22, 2022 · 4 shares · 766 followers View post →
Robbie Joosten
@Robbie_Joosten · X

RT @emblebi: Using #AlphaFold to help predict the structures of large protein complexes enabled researchers at @UWproteindesign, @UTSWnews,…

Jul 22, 2022 · 4 shares · 194 followers View post →
EMBL-EBI
@emblebi · X

Using #AlphaFold to help predict the structures of large protein complexes enabled researchers at @UWproteindesign, @UTSWnews, and colleagues to gain new insights into their vital biological functions. https://t.co/8vktioTbbn https://t.co/1Rz0BM5QYu

Jul 22, 2022 · 21 likes · 4 shares · 73,162 followers View post →
WCI
@WaltherCancerIn · X

RT @CascalesLab: Proteome-wide amino-acid coevolution and structural modeling using RoseTTAFold and AlphaFold2 identified new protein comp…

Jul 2, 2022 · 2 shares · 1,114 followers View post →
Protein Data Bank
@PDBeurope · X

@sandeepbiochem1 @emblebi @UWproteindesign @ISBSIB Hi Sandeep. You can get more information about how these predicted complexes were generated from the publication: https://t.co/mUTMkiwwIL

May 5, 2022 · 1 like · 22,121 followers View post →
AIExPro
@BaixingAILab · X

An article "Computed structures of core eukaryotic protein complexes."published in #Science by a team from #UTSMC & #UW. They developed a bioinformatics and deep learning pipeline to identify potentially interacting protein pairs and model the 3D structure of protein complexes. https://t.co/JzeLa4syMc

Mar 6, 2022 · 1 followers View post →
Fei Wu
@Fei65503306 · X

@biogerontology @A_Aspuru_Guzik @MLevitt_NP2013 Congrats! Maybe predicted protein-protein interaction (https://t.co/AMw56anGoL) could further help to validate your pathways from iPANDA/PandaOmics?

Jan 27, 2022 · 3 likes · 18 followers View post →
Edu Ocaña-Pallarès
@eduocapa · X

"We developed a coevolution-guided protein interaction identification pipeline that incorporates a rapidly computable version of RoseTTAFold with the slower but more accurate AlphaFold to evaluate interactions between 8.3 million pairs of yeast proteins." https://t.co/pukTGzjr80

Jan 18, 2022 · 2 likes · 536 followers View post →
David Juergens
@DaveJuergens · X

@andrewwhite01 @LindorffLarsen Totally possible! https://t.co/RerPiBLo3A

Dec 27, 2021 · 2 likes · 3,390 followers View post →
Dennis Lal
@LalDennis · X

Computed structures of core eukaryotic protein complexes https://t.co/XTkb2V5NtC https://t.co/xSMHVskoxB

Dec 23, 2021 · 1 like · 3,307 followers View post →
Saubashya Sur, PhD
@SaubashyaSur · X

RT @yeastgenome: Exciting @ScienceMagazine paper from David Baker's lab @UWproteindesign describes using deep-learning algorithms #AlphaFol…

Dec 18, 2021 · 27 shares · 766 followers View post →
amrojasm@bsky.social
@amrojasmendoza · X

RT @yeastgenome: Exciting @ScienceMagazine paper from David Baker's lab @UWproteindesign describes using deep-learning algorithms #AlphaFol…

Dec 18, 2021 · 27 shares · 1,321 followers View post →
@parag@micro.blog
@parags · X

This takes Alphafold predicted protein structures to the next level and will advance our understanding of molecular complexes. Computed structures of core eukaryotic protein complexes https://t.co/nz1RNKwohH

Dec 17, 2021 · 384 followers View post →
Ubik
@mr_ubik · X

RT @yeastgenome: Exciting @ScienceMagazine paper from David Baker's lab @UWproteindesign describes using deep-learning algorithms #AlphaFol…

Dec 17, 2021 · 27 shares · 447 followers View post →
☀️ ℝ
@rravi · X

RT @yeastgenome: Exciting @ScienceMagazine paper from David Baker's lab @UWproteindesign describes using deep-learning algorithms #AlphaFol…

Dec 17, 2021 · 27 shares · 1,514 followers View post →
LionKing 878
@878_lionking · X

RT @yeastgenome: Exciting @ScienceMagazine paper from David Baker's lab @UWproteindesign describes using deep-learning algorithms #AlphaFol…

Dec 17, 2021 · 27 shares · 64 followers View post →
Caroline Lynn Kamerlin
@kamerlinlab · X

RT @yeastgenome: Exciting @ScienceMagazine paper from David Baker's lab @UWproteindesign describes using deep-learning algorithms #AlphaFol…

Dec 17, 2021 · 27 shares · 8,519 followers View post →
Yaser Hashem
@Hashemyaser4 · X

RT @yeastgenome: Exciting @ScienceMagazine paper from David Baker's lab @UWproteindesign describes using deep-learning algorithms #AlphaFol…

Dec 17, 2021 · 27 shares · 1,224 followers View post →
Scott C Blanchard
@TheBlanchardLab · X

RT @yeastgenome: Exciting @ScienceMagazine paper from David Baker's lab @UWproteindesign describes using deep-learning algorithms #AlphaFol…

Dec 17, 2021 · 27 shares · 2,242 followers View post →
CK
@CK_KC_011010 · X

RT @yeastgenome: Exciting @ScienceMagazine paper from David Baker's lab @UWproteindesign describes using deep-learning algorithms #AlphaFol…

Dec 17, 2021 · 27 shares · 148 followers View post →
T Tian
@gdsttian · X

RT @yeastgenome: Exciting @ScienceMagazine paper from David Baker's lab @UWproteindesign describes using deep-learning algorithms #AlphaFol…

Dec 17, 2021 · 27 shares · 139 followers View post →
Kenneth Yaw Agyeman-Badu
@Kenzibit · X

RT @yeastgenome: Exciting @ScienceMagazine paper from David Baker's lab @UWproteindesign describes using deep-learning algorithms #AlphaFol…

Dec 17, 2021 · 27 shares · 1,629 followers View post →
Suhnylla Kler
@SuhnyllaKler · X

RT @yeastgenome: Exciting @ScienceMagazine paper from David Baker's lab @UWproteindesign describes using deep-learning algorithms #AlphaFol…

Dec 17, 2021 · 27 shares · 1,565 followers View post →
mitenaiy
@mitenaiy · X

RT @yeastgenome: Exciting @ScienceMagazine paper from David Baker's lab @UWproteindesign describes using deep-learning algorithms #AlphaFol…

Dec 17, 2021 · 27 shares · 245 followers View post →
Felipe Santibáñez Leal
@fsantiba · X

RT @yeastgenome: Exciting @ScienceMagazine paper from David Baker's lab @UWproteindesign describes using deep-learning algorithms #AlphaFol…

Dec 17, 2021 · 27 shares · 434 followers View post →
Emma Chan , PhD
@binggo203 · X

RT @yeastgenome: Exciting @ScienceMagazine paper from David Baker's lab @UWproteindesign describes using deep-learning algorithms #AlphaFol…

Dec 17, 2021 · 27 shares · 958 followers View post →
Diego Javier Zea
@diegojavierzea · X

RT @yeastgenome: Exciting @ScienceMagazine paper from David Baker's lab @UWproteindesign describes using deep-learning algorithms #AlphaFol…

Dec 17, 2021 · 27 shares · 982 followers View post →
123
@imagineNICE · X

RT @UWproteindesign: (1/8) Today we share the structures of protein complexes from nearly every core process in eukaryotic biology — from D…

Dec 16, 2021 · 258 shares · 147 followers View post →
CHARETTE LAB
@ribosome_asmbly · X

RT @yeastgenome: Exciting @ScienceMagazine paper from David Baker's lab @UWproteindesign describes using deep-learning algorithms #AlphaFol…

Dec 16, 2021 · 27 shares · 814 followers View post →
Olivier TOMAT
@oliviertomat · X

RT @yeastgenome: Exciting @ScienceMagazine paper from David Baker's lab @UWproteindesign describes using deep-learning algorithms #AlphaFol…

Dec 16, 2021 · 26 shares · 790 followers View post →
Nomad
@AuroraBoreas · X

RT @UWproteindesign: (1/8) Today we share the structures of protein complexes from nearly every core process in eukaryotic biology — from D…

Dec 16, 2021 · 258 shares · 103 followers View post →
P Kritsiligkou
@Parikki · X

RT @yeastgenome: Exciting @ScienceMagazine paper from David Baker's lab @UWproteindesign describes using deep-learning algorithms #AlphaFol…

Dec 16, 2021 · 27 shares · 762 followers View post →
Pierre Poulain
@pierrepo · X

RT @yeastgenome: Exciting @ScienceMagazine paper from David Baker's lab @UWproteindesign describes using deep-learning algorithms #AlphaFol…

Dec 16, 2021 · 27 shares · 1,615 followers View post →
SGD Project @yeastgenome@genomic.social (bsky too)
@yeastgenome · X

Exciting @ScienceMagazine paper from David Baker's lab @UWproteindesign describes using deep-learning algorithms #AlphaFold2 and #RoseTTAFold to model 3D structures of protein-protein interactions, including higher order complexes, in #yeast https://t.co/JSsfvbU1FL https://t.co/7gzPUMLEnY

Dec 16, 2021 · 123 likes · 27 shares · 3,423 followers View post →
Bastien Bissaro
@BastienBissaro · X

RT @EijsinkLab: Computed structures of core eukaryotic protein complexes https://t.co/IirHRfb1ZQ

Dec 15, 2021 · 1 share · 298 followers View post →
The PEP group
@EijsinkLab · X

Computed structures of core eukaryotic protein complexes https://t.co/IirHRfb1ZQ

Dec 15, 2021 · 3 likes · 1 share · 382 followers View post →
the paper link
@the_paper_link · X

RT @the_paper_link: Trend up+14: Humphreys IR, ..., Baker D (Science) __Computed structures of core eukaryotic protein complexes__ https:/…

Dec 12, 2021 · 1 share · 138 followers View post →
the paper link
@the_paper_link · X

Trend up+14: Humphreys IR, ..., Baker D (Science) __Computed structures of core eukaryotic protein complexes__ https://t.co/p86RkjNmhc

Dec 11, 2021 · 1 share · 138 followers View post →
Anubi_Inpw
@Anubi_Inpw · X

RT @manuelacasasoli: "Using #DeepLearning methods to systematically identify and build structures for the protein complexes that mediate ke…

Dec 10, 2021 · 6 shares · 7,124 followers View post →
Magnetic Resonance News
@nmr900 · X

RT @manuelacasasoli: "Using #DeepLearning methods to systematically identify and build structures for the protein complexes that mediate ke…

Dec 10, 2021 · 6 shares · 6,114 followers View post →
zach
@z4chburris · X

RT @manuelacasasoli: "Using #DeepLearning methods to systematically identify and build structures for the protein complexes that mediate ke…

Dec 10, 2021 · 6 shares · 348 followers View post →
Hao Yin
@HaoYin20 · X

RT @manuelacasasoli: "Using #DeepLearning methods to systematically identify and build structures for the protein complexes that mediate ke…

Dec 10, 2021 · 6 shares · 12,197 followers View post →
YOKONANABANBOSI
@yokonanabanbosi · X

RT @manuelacasasoli: "Using #DeepLearning methods to systematically identify and build structures for the protein complexes that mediate ke…

Dec 10, 2021 · 6 shares · 466 followers View post →
Manuela Casasoli
@manuelacasasoli · X

"Using #DeepLearning methods to systematically identify and build structures for the protein complexes that mediate key processes in eukaryotes." #Science #proteins #Biology #cells ⏯️Computed structures of core eukaryotic protein complexes https://t.co/v5jMcof4dJ https://t.co/kFHc1F8tgD

Dec 10, 2021 · 45 likes · 6 shares · 11,556 followers View post →
Francesco OTERI
@FrancescoOTERI3 · X

RT @julhenri: Computed structures of core eukaryotic protein complexes https://t.co/Yq2oQ7OSgE

Dec 10, 2021 · 1 share · 108 followers View post →
Julien Henri
@julhenri · X

Computed structures of core eukaryotic protein complexes https://t.co/Yq2oQ7OSgE

Dec 9, 2021 · 3 likes · 1 share · 513 followers View post →
the paper link
@the_paper_link · X

RT @the_paper_link: Trend up+25: Humphreys IR, ..., Baker D (Science) __Computed structures of core eukaryotic protein complexes__ https:/…

Dec 6, 2021 · 1 share · 138 followers View post →
the paper link
@the_paper_link · X

Trend up+25: Humphreys IR, ..., Baker D (Science) __Computed structures of core eukaryotic protein complexes__ https://t.co/p86RkjNmhc

Dec 6, 2021 · 1 share · 138 followers View post →
Javier Santoyo
@jsantoyo · X

Computed structures of core eukaryotic protein complexes. #ComputedComplexes #ProteinInteractions https://t.co/8A691hs62J @ScienceMagazine

Dec 3, 2021 · 6,082 followers View post →
Downtown Brown
@eigenspread · X

RT @UWproteindesign: (1/8) Today we share the structures of protein complexes from nearly every core process in eukaryotic biology — from D…

Dec 2, 2021 · 258 shares · 25 followers View post →
ลัคกี้ โหมดฤดูงาน
@sr_wiz · X

Computed structures of core eukaryotic protein complexes https://t.co/Bahi5UJCS1

Dec 1, 2021 · 1,612 followers View post →
the paper link
@the_paper_link · X

https://t.co/OvYJtb0b12 #prime3 Humphreys IR, ..., Baker D (Science) __Computed structures of core eukaryotic protein complexes__ https://t.co/p86RkjNmhc

Nov 29, 2021 · 138 followers View post →
luis hernan graffe
@hernangraffe · X

RT @hernangraffe: https://t.co/3Yzelf7fnR

Nov 27, 2021 · 1 share · 3,135 followers View post →
luis hernan graffe
@hernangraffe · X

https://t.co/3Yzelf7fnR

Nov 27, 2021 · 1 share · 3,135 followers View post →
Mathilde Gauchier
@M_Gauchier · X

https://t.co/WJ2R5iQMB5 Co-evolution guided proteome interactions, orthologs from paralogs...

Nov 27, 2021 · 78 followers View post →
Victor V. Lobanenkov
@boris_ctcf · X

AI Systematically IDs Structures of Eukaryotic Proteins. - A rather interesting commentary of results published in an article titled “Computed structures of core eukaryotic protein complexes” in the recent journal of Science. https://t.co/y96xMVaClX via @GENbio

Nov 27, 2021 · 1 like · 2,046 followers View post →
scientific humanism
@oker59 · X

Computed structures of core eukaryotic protein complexes - https://t.co/hArcXvW84H

Nov 25, 2021 · 277 followers View post →
Athale Lab: CyCelS
@AthaleLab · X

RT @UWproteindesign: (1/8) Today we share the structures of protein complexes from nearly every core process in eukaryotic biology — from D…

Nov 25, 2021 · 258 shares · 1,507 followers View post →
luis hernan graffe
@hernangraffe · X

RT @hernangraffe: https://t.co/3Yzelf7fnR

Nov 24, 2021 · 1 share · 3,135 followers View post →
Mo Khalil
@MoKhalilLab · X

RT @BUCNSB: Interesting article out in @ScienceMagazine on modeling eukaryotic protein complexes. https://t.co/7c55a2a2bk

Nov 24, 2021 · 1 share · 9,116 followers View post →
Center for Network Systems Biology, Boston U
@BUCNSB · X

Interesting article out in @ScienceMagazine on modeling eukaryotic protein complexes. https://t.co/7c55a2a2bk

Nov 24, 2021 · 5 likes · 1 share · 452 followers View post →
RJ Nowling
@discretestates · X

RT @EmilyLeproust: I’m more of a #DNA fan myself, but this is mind blowing work in structure prediction and interaction. @UWproteindesign…

Nov 23, 2021 · 12 shares · 1,064 followers View post →
BiolocoUSB
@biolocousb · X

RT @EmilyLeproust: I’m more of a #DNA fan myself, but this is mind blowing work in structure prediction and interaction. @UWproteindesign…

Nov 23, 2021 · 12 shares · 1,085 followers View post →
Carolina Soares
@C_FonsecaSoares · X

Incredible!! Computed structures of core eukaryotic protein complexes https://t.co/Z4CSkZ8IJd

Nov 23, 2021 · 400 followers View post →
Vastogen
@vastogen · X

RT @EmilyLeproust: I’m more of a #DNA fan myself, but this is mind blowing work in structure prediction and interaction. @UWproteindesign…

Nov 23, 2021 · 12 shares · 174 followers View post →
Rosario Strano
@Rosario_Strano · X

RT @EmilyLeproust: I’m more of a #DNA fan myself, but this is mind blowing work in structure prediction and interaction. @UWproteindesign…

Nov 23, 2021 · 12 shares · 6,986 followers View post →
Jacob Roberts
@jacoberts · X

RT @EmilyLeproust: I’m more of a #DNA fan myself, but this is mind blowing work in structure prediction and interaction. @UWproteindesign…

Nov 23, 2021 · 12 shares · 65 followers View post →
GEN Biotechnology
@GENBiotechJrnl · X

RT @EmilyLeproust: I’m more of a #DNA fan myself, but this is mind blowing work in structure prediction and interaction. @UWproteindesign…

Nov 23, 2021 · 12 shares · 2,541 followers View post →
Shaohe Wang
@snownontrace · X

RT @UWproteindesign: (1/8) Today we share the structures of protein complexes from nearly every core process in eukaryotic biology — from D…

Nov 23, 2021 · 258 shares · 669 followers View post →
Kaveh N
@kaveh_Nasr · X

RT @EmilyLeproust: I’m more of a #DNA fan myself, but this is mind blowing work in structure prediction and interaction. @UWproteindesign…

Nov 23, 2021 · 12 shares · 207 followers View post →
Sam Finlayson
@IAmSamFin · X

RT @EmilyLeproust: I’m more of a #DNA fan myself, but this is mind blowing work in structure prediction and interaction. @UWproteindesign…

Nov 23, 2021 · 12 shares · 5,263 followers View post →
Sten Linnarsson
@slinnarsson · X

RT @EmilyLeproust: I’m more of a #DNA fan myself, but this is mind blowing work in structure prediction and interaction. @UWproteindesign…

Nov 23, 2021 · 12 shares · 8,956 followers View post →
WeiTing Lin(GR15
@weitinglin66 · X

RT @EmilyLeproust: I’m more of a #DNA fan myself, but this is mind blowing work in structure prediction and interaction. @UWproteindesign…

Nov 22, 2021 · 12 shares · 1,289 followers View post →
Biotech Madoff
@biotech_madoff · X

RT @EmilyLeproust: I’m more of a #DNA fan myself, but this is mind blowing work in structure prediction and interaction. @UWproteindesign…

Nov 22, 2021 · 12 shares · 36 followers View post →
luis hernan graffe
@hernangraffe · X

https://t.co/3Yzelf7fnR

Nov 22, 2021 · 1 share · 3,135 followers View post →
Emily Leproust
@EmilyLeproust · X

I’m more of a #DNA fan myself, but this is mind blowing work in structure prediction and interaction. @UWproteindesign Computed structures of core eukaryotic protein complexes https://t.co/pf9DGgjDlI

Nov 22, 2021 · 50 likes · 12 shares · 14,162 followers View post →
Fei Wang
@Fei_Wang87 · X

RT @NatureBiotech: Deep learning predicts the structure of protein complexes based on paired multiple sequence alignments and amino acid co…

Nov 22, 2021 · 15 shares · 5 followers View post →
あさまさき
@kedama1202 · X

RT @Bio_stations: タンパク質"複合体"の構造を予測 近年進歩しているAIによるタンパク質の構造予測を複合体にも拡張。アミノ酸共振化解析と深層学習で真核生物のタンパク質複合体の構造を予測。機能未知の因子とかも見ている 時代の進歩すごい、!もう複合体も見れるの…

Nov 21, 2021 · 9 shares · 7 followers View post →
MarkQuarter
@MarkQuarter · X

RT @UWproteindesign: (1/8) Today we share the structures of protein complexes from nearly every core process in eukaryotic biology — from D…

Nov 20, 2021 · 258 shares · 1,602 followers View post →
Vladimir Y-Y
@vyy_sf · X

RT @UWproteindesign: (1/8) Today we share the structures of protein complexes from nearly every core process in eukaryotic biology — from D…

Nov 19, 2021 · 258 shares · 250 followers View post →
Vladimir Y-Y
@vyy_sf · X

RT @IanRHum: We use recent advances in proteome-wide coevolution analysis and breakthroughs in artificial-intelligence-based structure mode…

Nov 19, 2021 · 103 shares · 250 followers View post →
AI Bot
@Artificialbra1n · X

RT @sekmi: The artificial intelligence #AI revolution in #structuralbiology continues and begins a new era in which computation plays a fun…

Nov 19, 2021 · 5 shares · 1,962 followers View post →
the paper link
@the_paper_link · X

Trend up+7: Humphreys IR, ..., Baker D (Science) __Computed structures of core eukaryotic protein complexes__ https://t.co/p86RkjNmhc

Nov 19, 2021 · 138 followers View post →
Jean CAYEUX (Hour CET)
@jeancayeux · X

RT @RebeccaRambar: L'intelligence artificielle prédit avec succès les interactions entre des complexes protéiques eucaryotes selon une étud…

Nov 19, 2021 · 6 shares · 14,381 followers View post →
Hiroki Onoda
@onoda_hiroki · X

@t2438 それがあってもこの論文に近しい事をする能力も技術もないので止めておきます。 https://t.co/Y4tRCUq4uy

Nov 19, 2021 · 530 followers View post →
luis hernan graffe
@hernangraffe · X

RT @IanRHum: We use recent advances in proteome-wide coevolution analysis and breakthroughs in artificial-intelligence-based structure mode…

Nov 18, 2021 · 103 shares · 3,135 followers View post →
luis hernan graffe
@hernangraffe · X

RT @UWproteindesign: (1/8) Today we share the structures of protein complexes from nearly every core process in eukaryotic biology — from D…

Nov 18, 2021 · 258 shares · 3,135 followers View post →
AIMBE
@aimbe · X

RT @UWproteindesign: (1/8) Today we share the structures of protein complexes from nearly every core process in eukaryotic biology — from D…

Nov 18, 2021 · 258 shares · 4,171 followers View post →
Science Press Package
@scipak · X

SciPak Multimedia Highlight: Research on the structures and applications of eukaryotic protein complexes @UWproteindesign: https://t.co/N71XT79kzE Photo credit: Ian C. Haydon / UW Medicine Institute for Protein Design https://t.co/TQoh2HIuln

Nov 18, 2021 · 1 like · 4,867 followers View post →
Molecular and Cellular Biochemistry
@mole_biochem · X

RT @UWproteindesign: (1/8) Today we share the structures of protein complexes from nearly every core process in eukaryotic biology — from D…

Nov 18, 2021 · 258 shares · 5 followers View post →
BFML at UNIST
@bfml_unist · X

Computed structures of core eukaryotic protein complexes https://t.co/brURC0Bspy #generalscience #feedly

Nov 18, 2021 · 1,165 followers View post →
Akira Matsuura
@AkiraMatsuura · X

RT @Bio_stations: タンパク質"複合体"の構造を予測 近年進歩しているAIによるタンパク質の構造予測を複合体にも拡張。アミノ酸共振化解析と深層学習で真核生物のタンパク質複合体の構造を予測。機能未知の因子とかも見ている 時代の進歩すごい、!もう複合体も見れるの…

Nov 18, 2021 · 9 shares · 921 followers View post →
Ellen Allwood
@ellen_allwood · X

RT @UWproteindesign: (1/8) Today we share the structures of protein complexes from nearly every core process in eukaryotic biology — from D…

Nov 18, 2021 · 258 shares · 4 followers View post →
Ike Usawa
@IkeUsawa · X

Researchers used #AI & evolutionary analysis to make 3D models of eukaryotic #protein interactions. The #study found 100+ probable protein complexes for the first time and provided structural models for 700+ more. https://t.co/JUrarUWoXz #innovation https://t.co/QVYSsPvi3z

Nov 18, 2021 · 385 followers View post →
W.E.P.S.Y.
@_WEPSY_ · X

RT @ScienceMagazine: Using a combination of #RoseTTAFold and #AlphaFold to screen millions of pairs of yeast proteins, researchers in Scien…

Nov 17, 2021 · 42 shares · 27 followers View post →
Paul Lourdu Xavier
@PaulLXavier · X

RT @IanRHum: We use recent advances in proteome-wide coevolution analysis and breakthroughs in artificial-intelligence-based structure mode…

Nov 17, 2021 · 103 shares · 1,178 followers View post →
Nick Schnicker
@n_schnicker · X

RT @ScienceMagazine: Using a combination of #RoseTTAFold and #AlphaFold to screen millions of pairs of yeast proteins, researchers in Scien…

Nov 17, 2021 · 42 shares · 537 followers View post →
Yizhou (Eugene) Hu
@YizhouHu_Eugene · X

RT @ScienceMagazine: Using a combination of #RoseTTAFold and #AlphaFold to screen millions of pairs of yeast proteins, researchers in Scien…

Nov 17, 2021 · 42 shares · 218 followers View post →
Alessio G
@ptialex77 · X

RT @RebeccaRambar: L'intelligence artificielle prédit avec succès les interactions entre des complexes protéiques eucaryotes selon une étud…

Nov 17, 2021 · 6 shares · 658 followers View post →
hausa/a personal account
@metaphysicalsou · X

RT @ScienceMagazine: Using a combination of #RoseTTAFold and #AlphaFold to screen millions of pairs of yeast proteins, researchers in Scien…

Nov 17, 2021 · 42 shares · 1,412 followers View post →
ملتقى علوم الاحياء
@Biology1802 · X

RT @ScienceMagazine: Using a combination of #RoseTTAFold and #AlphaFold to screen millions of pairs of yeast proteins, researchers in Scien…

Nov 17, 2021 · 42 shares · 54,629 followers View post →
EtienneCartier
@EtienneCartier · X

RT @ScienceMagazine: Using a combination of #RoseTTAFold and #AlphaFold to screen millions of pairs of yeast proteins, researchers in Scien…

Nov 17, 2021 · 42 shares · 630 followers View post →
夢を見られた・・・⠠⠁⠍⠁⠝⠙⠁
@Amolain · X

RT @ScienceMagazine: Using a combination of #RoseTTAFold and #AlphaFold to screen millions of pairs of yeast proteins, researchers in Scien…

Nov 17, 2021 · 42 shares · 212 followers View post →
DOLORES VESTRICH
@DOLORESVESTRICH · X

Computed structures of core eukaryotic protein complexes https://t.co/ScacbdT7rC

Nov 17, 2021 · 1,758 followers View post →
Cascales Lab
@CascalesLab · X

Proteome-wide amino-acid coevolution and structural modeling using RoseTTAFold and AlphaFold2 identified new protein complexes and computed their structures. Computed structures of core eukaryotic protein complexes https://t.co/ETeOdAcCzf

Nov 16, 2021 · 8 likes · 2 shares · 4,558 followers View post →
Enrico Guarnera
@piproide · X

...and protein complexes! Computed structures of core eukaryotic protein complexes - https://t.co/M5tsy2BAK2 https://t.co/cE6luxVXX0

Nov 16, 2021 · 218 followers View post →
Twist Bioscience
@TwistBioscience · X

This is so cool! @UWProteinDesign makes protein structures freely available for almost all key processes in eukaryotic cells. #Alphafold, #RoseTTAFold Computed structures of core eukaryotic protein complexes https://t.co/5zfopf6McY

Nov 15, 2021 · 3 likes · 25,290 followers View post →
Andras Toth
@tothur · X

Computed structures of core eukaryotic protein complexes https://t.co/pW3UTTlT7F

Nov 14, 2021 · 1,822 followers View post →
matiere*
@matiere · X

Open-sourcing of protein-structure software is already paying off | Ars Technica https://t.co/uLXPabAbBg https://t.co/Gi854RElES

Nov 13, 2021 · 2,834 followers View post →
Edinburgh Watch
@EdinburghWatch · X

RT @jsantoyo: Computed structures of core eukaryotic protein complexes. #ProteinComplexes #ComputedStructures https://t.co/8A691hs62J @Scie…

Nov 13, 2021 · 1 share · 12,044 followers View post →
Javier Santoyo
@jsantoyo · X

Computed structures of core eukaryotic protein complexes. #ProteinComplexes #ComputedStructures https://t.co/8A691hs62J @ScienceMagazine

Nov 13, 2021 · 1 share · 6,082 followers View post →
Calì_Lab
@lab_cali · X

RT @_VerenaKohler: Computed structures of core eukaryotic protein complexes https://t.co/CV6FRiKrno

Nov 13, 2021 · 2 shares · 2,102 followers View post →
Verena Kohler
@_VerenaKohler · X

Computed structures of core eukaryotic protein complexes https://t.co/CV6FRiKrno

Nov 13, 2021 · 4 likes · 2 shares · 3,554 followers View post →
Alok Jha
@AlokGene · X

Computed structures of core eukaryotic protein complexes. https://t.co/YoABTY4ILX

Nov 12, 2021 · 359 followers View post →
Tominaga K. (tomiken)
@pacyc1841 · X

Computed structures of core eukaryotic protein complexes https://t.co/2pMO95SEag

Nov 12, 2021 · 855 followers View post →
Moustafa Saleh
@M_Saleh90 · X

Computed structures of core eukaryotic protein complexes https://t.co/ONTZb1ZAaZ

Nov 12, 2021 · 124 followers View post →
Ah-Ram Kim
@ahramkim1128 · X

Computed structures of core eukaryotic protein complexes https://t.co/TAIFvhpVo1

Nov 12, 2021 · 282 followers View post →
Rob Field, PVC Science, UEA
@Rob_Field_Lab · X

RT @KampranisLab: So many enzyme assemblies, not seen before, but could be very important for regulating growth and other key functions

Nov 12, 2021 · 1 share · 3,448 followers View post →
Pastel BioScience
@PastelBio · X

Computed structures of core eukaryotic protein complexes | https://t.co/3jHZQMcIcK #proteomics https://t.co/Z3kxuxNG05

Nov 12, 2021 · 1 like · 5,375 followers View post →
Destiny Konadu
@K_Destiny1 · X

RT @waynestatechem: #WSUchemistry's Tamara Hendrickson (@Prof_Tamara) and Travis Ness contributed to this important research article in @Sc…

Nov 12, 2021 · 1 share · 6,436 followers View post →
waynestatechem
@waynestatechem · X

#WSUchemistry's Tamara Hendrickson (@Prof_Tamara) and Travis Ness contributed to this important research article in @ScienceMagazine: "Computed structures of core #eukaryotic protein complexes." https://t.co/L06CcEudrx

Nov 12, 2021 · 8 likes · 1 share · 1,548 followers View post →
Kampranis Lab
@KampranisLab · X

So many enzyme assemblies, not seen before, but could be very important for regulating growth and other key functions

Nov 12, 2021 · 1 like · 1 share · 1,090 followers View post →
Yicheng Wang
@YichengWang16 · X

Amazing work using RoseTTAFold and AlphaFold predicts many yeast protein complexes, including a very reasonalbe model for GPI transamidase complex formed by 5 subunits!!! Computed structures of core eukaryotic protein complexes https://t.co/rhwYFvoVWx

Nov 12, 2021 · 1 like · 76 followers View post →
CrocodileChuck
@CrocodileChuck · X

Molecular Machines Are The Engines Of Biological Processes The Recently Parsed Computed Structures of Core Eukaryotic Protein Complexes: https://t.co/i1Z8R2H0LM… Hat Tip: Drew Berry, Replisome Animation https://t.co/xBXRnwVkSA

Nov 12, 2021 · 563 followers View post →
Hiroki Onoda
@onoda_hiroki · X

RT @tonets: あ、PPI予測やられたな? Computed structures of core eukaryotic protein complexes https://t.co/QqI4H0WyHn

Nov 12, 2021 · 5 shares · 530 followers View post →
Tomohito Higashi
@To_Higashi · X

RT @tonets: あ、PPI予測やられたな? Computed structures of core eukaryotic protein complexes https://t.co/QqI4H0WyHn

Nov 12, 2021 · 5 shares · 477 followers View post →
鈴仙
@URRK12 · X

RT @nob_mai: D. Bakerも複合体予測出してきた Computed structures of core eukaryotic protein complexes https://t.co/GZgmfwR7yf

Nov 12, 2021 · 3 shares · 409 followers View post →
a
@ayanosatoh · X

RT @tonets: あ、PPI予測やられたな? Computed structures of core eukaryotic protein complexes https://t.co/QqI4H0WyHn

Nov 12, 2021 · 5 shares · 621 followers View post →
Ohue M/大上雅史
@tonets · X

あ、PPI予測やられたな? Computed structures of core eukaryotic protein complexes https://t.co/QqI4H0WyHn

Nov 12, 2021 · 17 likes · 5 shares · 12,549 followers View post →
Ryota IINO 飯野亮太
@ryotaiino · X

Computed structures of core eukaryotic protein complexes https://t.co/d0EOIpzuZp

Nov 11, 2021 · 2 likes · 6,433 followers View post →
Sandeep Pulim
@SPulim · X

Computed structures of core eukaryotic protein complexes https://t.co/O8VOcmQEqC

Nov 11, 2021 · 5,340 followers View post →
LMBLib
@LMB_Library · X

NEW #LMBpublications Computed structures of core eukaryotic protein complexes https://t.co/cBVhcjuwXe

Nov 11, 2021 · 1 like · 318 followers View post →
Yutaka Maruyama
@drmaruyama · X

RT @nob_mai: D. Bakerも複合体予測出してきた Computed structures of core eukaryotic protein complexes https://t.co/GZgmfwR7yf

Nov 11, 2021 · 3 shares · 688 followers View post →
priya joseph
@ayirpelle · X

RT @westr: Computed structures of core eukaryotic protein complexes https://t.co/YekdQfna0R ... within the #yeast #proteome.

Nov 11, 2021 · 2 shares · 4,902 followers View post →
Kato
@oxkawaka · X

Computed structures of core eukaryotic protein complexes さぁ、RoseTTAFold と AlphaFoldのコンビで示してやるよ複合体たちの予測をなと言うお話。 https://t.co/yq2HpOSwzD

Nov 11, 2021 · 6 likes · 1 share · 5,814 followers View post →
Ramon Guixà-González
@ramonguixxa · X

Computed structures of core eukaryotic protein complexes https://t.co/XrIM8F03WK

Nov 11, 2021 · 1 like · 490 followers View post →
NobuoMaita
@nob_mai · X

D. Bakerも複合体予測出してきた Computed structures of core eukaryotic protein complexes https://t.co/GZgmfwR7yf

Nov 11, 2021 · 15 likes · 3 shares · 1,076 followers View post →
Jason H. Moore, PhD
@moorejh · X

RT @westr: Computed structures of core eukaryotic protein complexes https://t.co/YekdQfna0R ... within the #yeast #proteome.

Nov 11, 2021 · 2 shares · 34,224 followers View post →
Robert West, PhD ✝️
@westr · X

Computed structures of core eukaryotic protein complexes https://t.co/YekdQfna0R ... within the #yeast #proteome.

Nov 11, 2021 · 2 shares · 19,329 followers View post →
Cell Biology J-Club
@cell_club · X

Computed structures of core eukaryotic protein complexes https://t.co/DjZOiVBc1C

Nov 11, 2021 · 6,085 followers View post →
Tae Hoon Kim
@taehoonkim · X

Computed structures of core eukaryotic protein complexes https://t.co/6Gntm3eaKx

Nov 11, 2021 · 2 likes · 786 followers View post →
FrezzaLab
@FrezzaLab · X

Computed structures of core eukaryotic protein complexes https://t.co/Scls6r6pZn

Nov 11, 2021 · 3 likes · 1 share · 26,997 followers View post →