Biotechnol Bioeng February 2022 PMID 34778948

Systematic assessment of process analytical technologies for biologics.

Christopher Gillespie, Dhanuka P Wasalathanthri, Diana B Ritz, George Zhou, Keith A Davis, Thomas Wucherpfennig, Nadine Hazelwood

Mentions

12
Peak: 3 in Nov 2025
across 3 sources since Jan 2022

Extended reach

1,738
potential audience

Total likes

3

Video views

548

Mentions per month

Jan 2022 – Dec 2025

Where it's discussed

  • News7 articles
  • X / Twitter3 posts
  • YouTube2 videos

AI synopsis

What people are saying

The discussion highlights a recognition of the study's value with phrases like 'Worth a read,' but also emphasizes a lingering concern about limited funding for groundbreaking research in biopharma, indicating a cautious interest and moderate agreement. The tone suggests familiarity with the subject and a critical perspective on industry progress, aligning with neutral engagement and impact levels.

AgreementModerate agreement

The post shows moderate agreement, acknowledging the importance of the publication but expressing skepticism about the level of innovation in the industry.

InterestModerate interest

The discussion indicates some interest in the topic, but it’s somewhat limited to a general awareness rather than deep enthusiasm.

EngagementNeutral engagement

The post is brief and does not delve into detailed analysis or discussion, reflecting a neutral level of engagement.

ImpactNeutral impact

The reaction suggests the publication's content is somewhat impactful but not transformative, largely reaffirming existing views on industry innovation and funding.

Abstract in brief

  • This study evaluates the use of process analytical technologies (PAT) in biologics manufacturing, focusing on their technical benefits like process understanding and control, as well as their business advantages such as ease of implementation and cost savings.
  • Through an industry survey, the research identified high-value PAT tools like online liquid chromatography, inline Raman spectroscopy, and gas analysis during upstream processing, along with UV-Vis, light scattering, and automated sampling in downstream steps.
  • The insights aim to guide both current practitioners and newcomers in selecting and applying PAT tools effectively, enhancing the efficiency and quality of biotherapeutic development and production.]

Top posts

Most liked on X and Bluesky
Trent Munro
@trent_munro · X

Worth a read, but feel like industry Biopharma PD is not given sufficient blue sky research funding to change to paradigm of "next gen manufacturing", a little bit same old, same old... Systematic assessment of process analytical technologies for biologics https://t.co/jJEBCtgYnT

Jan 10, 2022 · 1 like · 998 followers View post →
CHO Cell Papers
@CHOculturePaper · X

Nov 27, 2025 · 62 followers View post →

All mentions

CHO Cell Papers
@CHOculturePaper · X

Nov 27, 2025 · 62 followers View post →
CHO Cell Papers
@CHOculturePaper · X

Oct 30, 2025 · 62 followers View post →
Trent Munro
@trent_munro · X

Worth a read, but feel like industry Biopharma PD is not given sufficient blue sky research funding to change to paradigm of "next gen manufacturing", a little bit same old, same old... Systematic assessment of process analytical technologies for biologics https://t.co/jJEBCtgYnT

Jan 10, 2022 · 1 like · 998 followers View post →
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