Omicron and Delta variant of SARS-CoV-2: A comparative computational study of spike protein.

Suresh Kumar, Thiviya S Thambiraja, Kalimuthu Karuppanan, Gunasekaran Subramaniam

April 2022 J Med Virol

Synopsis of Social media discussions

Discussions demonstrate a focus on the mutation details and biological implications of Omicron versus Delta, with posts mentioning mutation sharing, ACE2 binding affinity, and membrane fusion. The tone varies from informational to speculative, emphasizing scientific curiosity but not overall urgent impact, indicating a community engaging with the scientific nuances but with limited perception of immediate high impact.

A
Agreement
 Moderate agreement

Most discussions acknowledge the research, especially the computational findings on higher ACE2 affinity of Omicron and its distinct mutations, indicating general support or recognition of its relevance.

I
Interest
 High level of interest

Posts show high curiosity about Omicron's characteristics, its implications for the pandemic, and the mutation details, reflecting strong engagement with the topic.

E
Engagement
 Moderate level of engagement

Several posts reference specific findings, such as mutation comparisons and effects on infectivity, suggesting some deep engagement with the article's scientific data.

I
Impact
 Moderate level of impact

While some discussions hint at the future implications, such as the potential for Omicron to signify the 'beginning of the end,' many focus on scientific details rather than immediate policy or health impacts.

Social Mentions

YouTube

2 Videos

Facebook

11 Posts

Twitter

46 Posts

Blogs

2 Articles

News

4 Articles

Metrics

Video Views

39,429

Total Likes

1,199

Extended Reach

299,944

Social Features

65

Timeline: Posts about article

Top Social Media Posts

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  • Scott Fournier
    @scott4nier (Twitter)

    @normanpie @ClareCraigPath What is your rebuttal to the evidence presented in the the Kumar et al. study? "Omicron and Delta variant of SARS-CoV-2: A comparative computational study of spike protein"
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    May 4, 2025

  • suresh
    @MsuSuresh (Twitter)

    First to report- Omicron variant is less harmful to the lower respiratory tract (2/2) Publication link: https://t.co/NDiiXiKnaO @MSUmalaysia @MSUmalaysiaFHLS @researchMSU
    view full post

    December 1, 2023

  • suresh
    @MsuSuresh (Twitter)

    Achievements of our group (2022-2023) (1/1) 1. First to report: Omicron Variant will have higher transmission: Received Highest citation, Highly Read and Highly Downloaded article certificate. Publication: https://t.co/NDiiXiKnaO @MSUmalaysia @MSUmalaysiaFHLS @researchMSU https://t.co/QwK7vwPI40
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    December 1, 2023

  • suresh
    @MsuSuresh (Twitter)

    I am glad that our work published in 2021 in Journal of Medical Virology received certificate of appreciation from Journal for top cited, top downloaded and most read in 2022. #SARSCoV2 #COVID19 #Bioinformatics #omicron https://t.co/Hs50pW5l71
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    May 9, 2023

  • Armand du Plessis
    @Armandd59974822 (Twitter)

    @djkom1978 En ce qui concerne le variant omicron, il se distingue en particulier par des mutations de la protéine spike, par rapport à d'autres variants notables tels que le delta: https://t.co/LYD2Pkh5fM
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    October 13, 2022

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  • riddick
    @riddickghost13 (Twitter)

    @alexandrosM https://t.co/KevI6yegQm
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    August 30, 2022

  • M
    @0xcd16 (Twitter)

    @hjelle_brian NB Omicron shared 3 out of Delta's 10 Spike mutations (colored red by me). Are we ever going to see another variant without D614G? At what point do we update the boosters from Wuhan-Hu-1 - and to what? (I have no idea!) https://t.co/fR96QX7a36 https://t.co/71FrGmXBHy
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    April 1, 2022

    1

  • Andromaque@1984
    @Andromaque19841 (Twitter)

    Ce serait pas à cause de ça ??? https://t.co/qUZYBp9qot
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    March 30, 2022

  • Daniel Kerlinsky MD
    @DrDan20000 (Twitter)

    Omicron and Delta variant of SARS‐CoV‐2: A comparative computational study of spike protein - Kumar - 2022 - Journal of Medical Virology - Wiley Online Library https://t.co/5dHyZlmTP6
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    March 22, 2022

  • suresh
    @MsuSuresh (Twitter)

    Our Publication covered in news media- #delta and #Omicron Of #SARSCoV2 comparison. https://t.co/omVihnH6mR https://t.co/l5hbKVBEvI
    view full post

    February 26, 2022

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  • n_ataie
    @n_ataie (Twitter)

    RT @n_ataie: There are a large number of mutational differences between Delta/original Covid and Omicron. This needed an explanation. The v…
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    February 6, 2022

    1

  • Mariola Zwolak
    @ZwolakMariola (Twitter)

    https://t.co/oDTFbKAYeD
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    January 30, 2022

  • n_ataie
    @n_ataie (Twitter)

    There are a large number of mutational differences between Delta/original Covid and Omicron. This needed an explanation. The virus was evolving at a certain rate, then suddenly we see an acceleration, what can account for this? https://t.co/O0GF3iFqR7 https://t.co/0LkVkcB3Q9
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    January 30, 2022

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  • müller
    @mller55938632 (Twitter)


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    January 30, 2022

  • Ananda
    @Ananda10149510 (Twitter)

    RT @PatrickSSte: @Daoyu15 @tony_vandongen @breakfast_dogs @dmoulding 1/ Morning everyone I'm confused about Omicron now I think it's clea…
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    January 14, 2022

    1

  • Patrick Shaw Stewart
    @PatrickSSte (Twitter)

    @Daoyu15 @tony_vandongen @breakfast_dogs @dmoulding 1/ Morning everyone I'm confused about Omicron now I think it's clear that Om's a very different strain from previous variants because it doesn’t fuse membranes ⬇️ https://t.co/EQL60fco8h https://t.co/y1iVV00uQz
    view full post

    January 14, 2022

    2

    1

  • 四谷言ノ助
    @g_yotuya (Twitter)

    @nukomarun 翻訳して読んでいただければ。 かなり違います。 https://t.co/ZcuCeWIiAT
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    January 13, 2022

  • j christian
    @jchrist57239072 (Twitter)

    RT @PatrickSSte: A recent paper shows that Omicron Spike probably doesn’t fuse cells like eg Delta, which suggests that Spike no longer "fl…
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    January 12, 2022

    1

  • Patrick Shaw Stewart
    @PatrickSSte (Twitter)

    A recent paper shows that Omicron Spike probably doesn’t fuse cells like eg Delta, which suggests that Spike no longer "flips"⬇️ https://t.co/EQL60fco8h https://t.co/2pHHOgSx3A
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    January 11, 2022

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  • Patrick Shaw Stewart
    @PatrickSSte (Twitter)

    @K_G_Andersen @macroliter @stuartjdneil Om spike is predicted to bind ACE2 with higher affinity than Delta https://t.co/EQL60fco8h However it doesn't appear to cause ANY cell-cell fusion⬇️ https://t.co/EQL60fco8h It seems possible that it no longer "flips" with all those disruptive mutations https://t.co/jgD0Oo0As9
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    January 11, 2022

    2

  • 四谷言ノ助
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    @disco_v8 ああ、あった https://t.co/ZcuCeWIiAT
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    January 10, 2022

    1

  • News Diversifier
    @NewsDiversifier (Twitter)

    Hey @MikeParrot87: url | source | doi 1) https://t.co/uhLVN2rUCr | Medline | 10.1038/s41467-021-27369-3 2) https://t.co/j3u7jyd0GN | Medline | 10.1002/jmv.27526
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    January 8, 2022

  • En la Puerta de Urgencias
    @p_de_urgencias (Twitter)

    ¿Es ómicron el principio del fin de la pandemia? #OmicronVarient #pandemia #coronavirus https://t.co/v3CcckNSP5
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    January 7, 2022

  • OmicronVariant
    @OmicronDaily (Twitter)

    Omicron and Delta Variant of SARS‐CoV‐2: A Comparative Computational Study of Spike Protein https://t.co/1Ta0CmhmEy #Omicron #OmicronVariant #b11529
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    December 17, 2021

  • Phage Papers
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    Omicron and Delta Variant of SARS-CoV-2: A Comparative Computational Study of Spike Protein https://t.co/rUs8NjFm4L
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    December 16, 2021

  • Apolinar Picado Jr.
    @ilsvezio (Twitter)

    Omicron and Delta Variant of SARS-CoV-2: A Comparative Computational Study of Spike protein https://t.co/ccT4xuyWpX
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    December 6, 2021

  • Dr Elizabeth Annabel O'Donnell PhD CPsychol
    @AnnabelDonnell (Twitter)

    Omicron and Delta Variant of SARS-CoV-2: A Comparative Computational Study of Spike protein https://t.co/4TuB9oeYLZ
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  • Isatou Sarr
    @IsatouSarr4 (Twitter)

    Omicron and Delta Variant of SARS-CoV-2: A Comparative Computational Study of Spike protein https://t.co/KApt4xNZQj
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    December 6, 2021

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  • MASALUD Laboratorio Clínico
    @masalud1 (Twitter)

    RT @emulenews: #bioRxiv Omicron and Delta Variant of SARS-CoV-2: A Comparative Computational Study of Spike protein https://t.co/Z2BNxKJbqz…
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    December 5, 2021

    6

  • Enrique Viguera
    @EnriqueViguera (Twitter)

    RT @emulenews: #bioRxiv Omicron and Delta Variant of SARS-CoV-2: A Comparative Computational Study of Spike protein https://t.co/Z2BNxKJbqz…
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    December 5, 2021

    6

  • Angel Galan Galan
    @AngelGalanGalan (Twitter)

    RT @emulenews: #bioRxiv Omicron and Delta Variant of SARS-CoV-2: A Comparative Computational Study of Spike protein https://t.co/Z2BNxKJbqz…
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    December 5, 2021

    6

  • Nisus Medical
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    RT @emulenews: #bioRxiv Omicron and Delta Variant of SARS-CoV-2: A Comparative Computational Study of Spike protein https://t.co/Z2BNxKJbqz…
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    December 5, 2021

    6

  • Jaime Díez
    @astrofotografia (Twitter)

    RT @emulenews: #bioRxiv Omicron and Delta Variant of SARS-CoV-2: A Comparative Computational Study of Spike protein https://t.co/Z2BNxKJbqz…
    view full post

    December 5, 2021

    6

  • Francis Villatoro
    @emulenews (Twitter)

    #bioRxiv Omicron and Delta Variant of SARS-CoV-2: A Comparative Computational Study of Spike protein https://t.co/Z2BNxKJbqz computational studies found that the Omicron variant had a higher affinity for human ACE2 than the Delta variant. https://t.co/HubGlrKgR9
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    December 5, 2021

    13

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  • PromisingPreprints
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    Omicron and Delta Variant of SARS-CoV-2: A Comparative Computational Study of Spike protein https://t.co/oSJBXVBMvL
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    December 5, 2021

  • K.S. Chew
    @cksheng74 (Twitter)

    Omicron and Delta Variant of SARS-CoV-2: A Comparative Computational Study of Spike protein https://t.co/VYlanljD6y
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    December 5, 2021

  • troy
    @_tjganz_ (Twitter)

    RT @biorxivpreprint: Omicron and Delta Variant of SARS-CoV-2: A Comparative Computational Study of Spike protein https://t.co/e3hIrK8W1L #…
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    December 4, 2021

    1

  • HelmaHase
    @HaseHelma (Twitter)

    Omicron and Delta Variant of SARS-CoV-2: A Comparative Computational Study of Spike protein https://t.co/ORwvxCsiAm
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    December 4, 2021

  • Sushil Pokhrel
    @sushilpokhrel (Twitter)

    Omicron and Delta Variant of SARS-CoV-2: A Comparative Computational Study of Spike protein https://t.co/Fq5z3XvQzT
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    December 4, 2021

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  • Zohra Bulgari
    @BulgariZohra (Twitter)

    Omicron and Delta Variant of SARS-CoV-2: A Comparative Computational Study of Spike protein https://t.co/KSjANEbv5z Рецептор-связывающий домен Omicron с его 15 мутациями по сравнению с 2-мя мутациями Delta, и, согласно прогнозам, это приводит к более высокому связыванию/
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    December 4, 2021

  • Gris
    @degogrim (Twitter)

    Omicron and Delta Variant of SARS-CoV-2: A Comparative Computational Study of Spike protein | bioRxiv https://t.co/LBeIHs8XLX
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    December 4, 2021

  • Enrico K.
    @vt27kolt11 (Twitter)

    Omicron and Delta Variant of SARS-CoV-2: A Comparative Computational Study of Spike protein https://t.co/ICWWFR5i2c
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    December 4, 2021

  • Helio Rocha
    @_elioRocha (Twitter)

    #bioRxiv Omicron and Delta Variant of SARS-CoV-2: A Comparative Computational Study of Spike protein #bioinfo https://t.co/cMRJcMUNNr
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    December 4, 2021

  • giovanni dall'olio
    @giovannidalloli (Twitter)

    Omicron and Delta Variant of SARS-CoV-2: A Comparative Computational Study of Spike protein https://t.co/I6lytgQbdC"
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    December 3, 2021

  • bioRxiv Bioinfo
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    Omicron and Delta Variant of SARS-CoV-2: A Comparative Computational Study of Spike protein https://t.co/gLt3xP051z #biorxiv_bioinfo
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    December 3, 2021

    1

  • bioRxiv
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    Omicron and Delta Variant of SARS-CoV-2: A Comparative Computational Study of Spike protein https://t.co/e3hIrK8W1L #bioRxiv
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    December 3, 2021

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