Arch Toxicol February 2022 PMID 34988610

Methanol-induced optic neuropathy: a still-present problem.

Sławomir Liberski, Bartlomiej J Kaluzny, Jarosław Kocięcki

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Mentions

Peak: 2 in Jan 2022

across 3 sources since Jan 2022

Extended reach

9,365

potential audience

Total likes

299

Video views

7,053

Mentions per month

Jan 2022 – Oct 2025

Where it's discussed

X / Twitter3 posts
YouTube3 videos
News2 articles

AI synopsis

What people are saying

Discussions show strong agreement with the article by referencing the longstanding knowledge of methanol’s toxicity, as in the comment about 'literally 1000s of papers,' which underscores the severity and historical recognition of the issue. The tone combines concern with factual reference, revealing both a recognition of ongoing problems and a desire to reinforce public awareness of methanol's dangers.

AgreementModerate agreement

Several discussions confirm the ongoing danger of methanol toxicity and support the article's emphasis on its relevance.

InterestHigh interest

Social discussions demonstrate high curiosity about the topic, especially regarding its long history and persistent issues.

EngagementModerate engagement

Posts reference broader research and emphasize the need to recognize methanol's dangers, indicating a moderate depth of engagement.

ImpactModerate impact

While not universally declared as transformative, discussions highlight the importance of awareness and continued research in this area.

Abstract in brief

Methanolinduced optic neuropathy (MeION) is a serious condition that can cause long-term or permanent vision loss due to damage to the optic nerve and retina, especially in poorer developing countries where mass poisonings are more common.
The primary cause of MeION is the inhibition of mitochondrial energy production caused by formic acid, a toxic metabolite of methanol, which damages eye tissues through mechanisms like oxidative stress and inflammation.
Despite advances in treatment, many survivors still experience significant vision problems, making MeION an ongoing global health concern that requires continued attention and intervention.

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