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Nat Methods January 2022 PMID 35017724

Deep learning and protein structure modeling.

Minkyung Baek, David Baker

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Mentions

26
Peak: 18 in Jan 2022
across 3 sources since Jan 2022

Extended reach

228,747
potential audience

Total likes

82

Video views

498

Mentions per month

Jan 2022 – Apr 2023

Where it's discussed

  • X / Twitter22 posts
  • YouTube2 videos
  • Blogs2 articles

AI synopsis

What people are saying

The discussions primarily highlight the promising capabilities of deep learning models like RoseTTAFold and AlphaFold, emphasizing their role in predicting protein structures from sequences. Words such as 'revolutionized' and 'significantly advanced' convey a sense of importance and optimism, though the tone remains largely supportive without deep critique or technical debate.

AgreementModerate agreement

Most discussions acknowledge the significance of deep learning in advancing protein structure prediction, with phrases like 'significantly advanced' and 'revolutionized' reflecting broad support.

InterestModerate interest

Comments show moderate curiosity, as evidenced by mentions of methods like RoseTTAFold and AlphaFold, but lack detailed analysis or skepticism.

EngagementNeutral engagement

The overall engagement appears neutral, with references to methods and articles but limited depth or critical evaluation in the discussions.

ImpactModerate impact

The discussions recognize the potential of these technologies to impact fields such as drug discovery and bioinformatics, indicating a notable but not overwhelming perceived influence.

Abstract in brief

  • Deep learning has revolutionized protein structure modeling by enabling more accurate predictions of 3D structures from amino acid sequences.
  • Techniques like neural networks and algorithms such as AlphaFold have significantly advanced the understanding of protein folding and interactions.
  • These developments are crucial for drug discovery, understanding diseases, and designing new proteins with specific functions.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Jason H. Moore, PhD
@moorejh · X

Deep learning and protein structure modeling https://t.co/Pf3WnhOjBv #deeplearning #bioinformatics

Jan 13, 2022 · 50 likes · 11 shares · 34,216 followers View post →
Kresten Lindorff-Larsen
@LindorffLarsen · X

@michael_nielsen It's still not clear exactly how these methods work, but there are indications they have learnt some "physics". This means, for example, that RoseTTAFold (similar to AF) can predict structures of some designed proteins from just a single sequence https://t.co/EV2Go9mgLL https://t.co/JXIxnR1As7

Apr 13, 2023 · 6 likes · 14,524 followers View post →
Data science
@Datascience__ · X

Deep learning and protein structure modeling | Nature Methods https://t.co/UrLRP07ZwB #DeepLearning

Jan 18, 2022 · 3 likes · 1 share · 33,275 followers View post →
Data science
@Datascience__ · X

Deep learning and protein structure modeling - Methods https://t.co/VF2jdbNhXq #DeepLearning

Feb 2, 2022 · 2 likes · 1 share · 33,275 followers View post →
Data science
@Datascience__ · X

Deep learning and protein structure modeling - Methods https://t.co/VF2jdbNhXq #DeepLearning

Jan 12, 2022 · 1 share · 33,275 followers View post →
Data science
@Datascience__ · X

Deep learning and protein structure modeling - Methods https://t.co/VF2jdbNhXq #DeepLearning

Feb 6, 2022 · 33,275 followers View post →

All mentions

Kresten Lindorff-Larsen
@LindorffLarsen · X

@michael_nielsen It's still not clear exactly how these methods work, but there are indications they have learnt some "physics". This means, for example, that RoseTTAFold (similar to AF) can predict structures of some designed proteins from just a single sequence https://t.co/EV2Go9mgLL https://t.co/JXIxnR1As7

Apr 13, 2023 · 6 likes · 14,524 followers View post →
Data science
@Datascience__ · X

Deep learning and protein structure modeling - Methods https://t.co/VF2jdbNhXq #DeepLearning

Feb 6, 2022 · 33,275 followers View post →
#ghost
@O_G_Log · X

RT @Datascience__: Deep learning and protein structure modeling - Methods https://t.co/VF2jdbNhXq #DeepLearning

Feb 2, 2022 · 1 share · 4,918 followers View post →
Data science
@Datascience__ · X

Deep learning and protein structure modeling - Methods https://t.co/VF2jdbNhXq #DeepLearning

Feb 2, 2022 · 2 likes · 1 share · 33,275 followers View post →
EliZa BOT
@elizabot9 · X

RT @moorejh: Deep learning and protein structure modeling https://t.co/Pf3WnhOjBv #deeplearning #bioinformatics

Jan 22, 2022 · 11 shares · 481 followers View post →
HubOfML
@hubofml · X

RT @moorejh: Deep learning and protein structure modeling https://t.co/Pf3WnhOjBv #deeplearning #bioinformatics

Jan 22, 2022 · 11 shares · 9,015 followers View post →
Richard Kim ↙️
@richardkimphd · X

RT @Datascience__: Deep learning and protein structure modeling | Nature Methods https://t.co/UrLRP07ZwB #DeepLearning

Jan 18, 2022 · 1 share · 4,645 followers View post →
Data science
@Datascience__ · X

Deep learning and protein structure modeling | Nature Methods https://t.co/UrLRP07ZwB #DeepLearning

Jan 18, 2022 · 3 likes · 1 share · 33,275 followers View post →
Kevin Morgan
@KevinMo95499403 · X

Deep learning and protein structure modeling https://t.co/dPR4gk2WyQ

Jan 17, 2022 · 68 followers View post →
Bacterial ChemBot
@bacterialchem · X

RT @moorejh: Deep learning and protein structure modeling https://t.co/Pf3WnhOjBv #deeplearning #bioinformatics

Jan 15, 2022 · 11 shares · 310 followers View post →
BiolocoUSB
@biolocousb · X

RT @moorejh: Deep learning and protein structure modeling https://t.co/Pf3WnhOjBv #deeplearning #bioinformatics

Jan 15, 2022 · 11 shares · 1,091 followers View post →
EGLlilly
@EGL_Lilly · X

RT @moorejh: Deep learning and protein structure modeling https://t.co/Pf3WnhOjBv #deeplearning #bioinformatics

Jan 14, 2022 · 11 shares · 24 followers View post →
HubOfML
@hubofml · X

RT @moorejh: Deep learning and protein structure modeling https://t.co/Pf3WnhOjBv #deeplearning #bioinformatics

Jan 14, 2022 · 11 shares · 9,015 followers View post →
Alexander Neils
@360CRISPRCAS · X

RT @moorejh: Deep learning and protein structure modeling https://t.co/Pf3WnhOjBv #deeplearning #bioinformatics

Jan 14, 2022 · 11 shares · 91 followers View post →
Mo Salinas
@MoSalinas_ · X

RT @moorejh: Deep learning and protein structure modeling https://t.co/Pf3WnhOjBv #deeplearning #bioinformatics

Jan 14, 2022 · 11 shares · 121 followers View post →
Muhammad Asim Javed
@asimjaved777 · X

RT @moorejh: Deep learning and protein structure modeling https://t.co/Pf3WnhOjBv #deeplearning #bioinformatics

Jan 13, 2022 · 11 shares · 493 followers View post →
Bioinformatics Trends 
@BinfoTrends · X

RT @moorejh: Deep learning and protein structure modeling https://t.co/Pf3WnhOjBv #deeplearning #bioinformatics

Jan 13, 2022 · 11 shares · 8,157 followers View post →
CompChemBio Bot
@CompChemBioBot · X

RT @moorejh: Deep learning and protein structure modeling https://t.co/Pf3WnhOjBv #deeplearning #bioinformatics

Jan 13, 2022 · 11 shares · 2,761 followers View post →
Jason H. Moore, PhD
@moorejh · X

Deep learning and protein structure modeling https://t.co/Pf3WnhOjBv #deeplearning #bioinformatics

Jan 13, 2022 · 50 likes · 11 shares · 34,216 followers View post →
Richard Kim ↙️
@richardkimphd · X

RT @Datascience__: Deep learning and protein structure modeling - Methods https://t.co/VF2jdbNhXq #DeepLearning

Jan 12, 2022 · 1 share · 4,645 followers View post →
Data science
@Datascience__ · X

Deep learning and protein structure modeling - Methods https://t.co/VF2jdbNhXq #DeepLearning

Jan 12, 2022 · 1 share · 33,275 followers View post →
TechontheEdge
@Tech_on_Edge · X

Most tweeted articles today in Deep Learning: - Deep learning and protein structure modeling, #AI #bigdata #DataScience #ArtificialIntelligence #neuralnetworks Read all new articles on: https://t.co/9Zxi644ZyJ , https://t.co/l0Cb2DZgDN

Jan 11, 2022 · 299 followers View post →