Stride-level analysis of mouse open field behavior using deep-learning-based pose estimation.

Keith Sheppard, Justin Gardin, Gautam S Sabnis, Asaf Peer, Megan Darrell, Sean Deats, Brian Geuther, Cathleen M Lutz, Vivek Kumar

January 2022 Cell Rep

Synopsis of Social media discussions

The discussions emphasize the importance of reproducibility through mentions of RRIDs and highlight the study's broad utility across multiple papers, indicating deep engagement with the research’s methods and implications. Words like 'utility,' 'support,' and 'reproducibility' suggest positive consensus about the study’s impact and significance in advancing mouse behavior analysis.

A
Agreement
 Moderate agreement

Most discussions recognize the scientific value and reproducibility aspects of the study, indicating overall support, though some may show mild skepticism about generalizability.

I
Interest
 High level of interest

The posts display high interest, with mentions of the utility of video data, specific methods, and the significance of the findings for understanding ASD and gait traits.

E
Engagement
 Moderate level of engagement

Several posts delve into methodological details, such as the inclusion of RRIDs and the implications for reproducibility, reflecting thoughtful engagement.

I
Impact
 High level of impact

There is a consensus that the study’s contributions—like high accuracy analysis across multiple strains and insights into heritability—could influence future research directions significantly.

Social Mentions

YouTube

1 Videos

Twitter

8 Posts

News

2 Articles

Metrics

Video Views

221

Total Likes

7

Extended Reach

4,913

Social Features

11

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

Advanced Gait Analysis Using DeepLabCut and Pose Estimation Techniques

Advanced Gait Analysis Using DeepLabCut and Pose Estimation Techniques

This Python-based tool provides a detailed analysis of animal behavior in videos, focusing on tests like openfield. It leverages modern pose estimation data from DeepLabCut models to generate data summaries and visualizations of key metrics, including gait and posture analysis.

NeuroTech

July 27, 2025

221 views

  • Vivek Kumar
    @Vivekdna (Twitter)

    The dataset was used in the following papers, a true testament to the utility of video data. - https://t.co/UofLNYPXrU - https://t.co/r9L05a2Kwx - https://t.co/DogHpPV1xb - https://t.co/Qh2ZTqwA4h
    view full post

    August 8, 2024

  • Vivek Kumar
    @Vivekdna (Twitter)

    Example papers from our lab: Mouse Grooming https://t.co/iEDgadAUYR Mouse Pose and Gait https://t.co/DogHpPUtHD Mouse Frailty https://t.co/UOS79KDbQ7
    view full post

    June 13, 2023

    3

  • Diego Forero MD, PhD
    @daforerog (Twitter)

    Stride-level analysis of mouse open field behavior using deep-learning-based pose estimation https://t.co/3OFDpfGFt0
    view full post

    February 7, 2022

  • RRID Robot
    @RobotRrid (Twitter)

    RRIDs were included in the Cell Reports paper "Stride-level analysis of mouse open field behavior…" (https://t.co/EWLrDK529v). RRIDs like this improve reproducibility in scientific research. #RRID #methodsmatter
    view full post

    February 2, 2022

  • RRID Robot
    @RobotRrid (Twitter)

    RRIDs were included in the Cell Reports paper "Stride-level analysis of mouse open field behavior…" (https://t.co/EWLrDK529v). We appreciate the author's support of reproducibility. #RRID #STMpublishing
    view full post

    January 17, 2022

  • robo_gwas
    @robo_gwas (Twitter)

    Stride-level analysis of mouse open field behavior using deep-learning-based pose estimation https://t.co/WujWkZAb1p
    view full post

    January 13, 2022

  • Psychiatric Genomics Bot
    @PsychGenPapers (Twitter)

    Stride-level analysis of mouse open field behavior using deep-learning-based pose estimation https://t.co/XnbaVL8RiO
    view full post

    January 13, 2022

    1

  • neuropsychgenpapers
    @neuropsychgenp1 (Twitter)

    Stride-level analysis of mouse open field behavior using deep-learning-based pose estimation https://t.co/m1oV9yiCVd https://t.co/6mkmuFXSGt
    view full post

    January 13, 2022

    1

Abstract Synopsis

  • This study introduces a machine learning-based method to analyze mouse gait and posture in an open field setup, achieving high accuracy across 62 different mouse strains.
  • Researchers used this method to examine four mutants with known gait issues and found that many autism spectrum disorder (ASD) mouse models also display gait and posture problems, suggesting these are common features of ASD.
  • The study shows that mouse gait and posture traits are highly heritable, can be grouped into three categories, and their genetic basis was explored through a genome-wide association study, providing a valuable resource for future research.]