Cell Rep January 2022 PMID 35021077

Stride-level analysis of mouse open field behavior using deep-learning-based pose estimation.

Keith Sheppard, Justin Gardin, Gautam S Sabnis, Asaf Peer, Megan Darrell, Sean Deats, Brian Geuther, Cathleen M Lutz, Vivek Kumar

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Mentions

Peak: 4 in Jan 2022

across 3 sources since Jan 2022

Extended reach

4,913

potential audience

Total likes

Video views

221

Mentions per month

Jan 2022 – Jul 2025

Where it's discussed

X / Twitter8 posts
News2 articles
YouTube1 videos

AI synopsis

What people are saying

The discussions emphasize the importance of reproducibility through mentions of RRIDs and highlight the study's broad utility across multiple papers, indicating deep engagement with the research’s methods and implications. Words like 'utility,' 'support,' and 'reproducibility' suggest positive consensus about the study’s impact and significance in advancing mouse behavior analysis.

AgreementModerate agreement

Most discussions recognize the scientific value and reproducibility aspects of the study, indicating overall support, though some may show mild skepticism about generalizability.

InterestHigh interest

The posts display high interest, with mentions of the utility of video data, specific methods, and the significance of the findings for understanding ASD and gait traits.

EngagementModerate engagement

Several posts delve into methodological details, such as the inclusion of RRIDs and the implications for reproducibility, reflecting thoughtful engagement.

ImpactHigh impact

There is a consensus that the study’s contributions—like high accuracy analysis across multiple strains and insights into heritability—could influence future research directions significantly.

Abstract in brief

This study introduces a machine learning-based method to analyze mouse gait and posture in an open field setup, achieving high accuracy across 62 different mouse strains.
Researchers used this method to examine four mutants with known gait issues and found that many autism spectrum disorder (ASD) mouse models also display gait and posture problems, suggesting these are common features of ASD.
The study shows that mouse gait and posture traits are highly heritable, can be grouped into three categories, and their genetic basis was explored through a genome-wide association study, providing a valuable resource for future research.]

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All mentions

Advanced Gait Analysis Using DeepLabCut and Pose Estimation Techniques

This Python-based tool provides a detailed analysis of animal behavior in videos, focusing on tests like openfield. It leverages modern pose estimation data from DeepLabCut models to generate data summaries and…

NeuroTech · Jul 27, 2025 221 views

Vivek Kumar

@Vivekdna · X

The dataset was used in the following papers, a true testament to the utility of video data. - https://t.co/UofLNYPXrU - https://t.co/r9L05a2Kwx - https://t.co/DogHpPV1xb - https://t.co/Qh2ZTqwA4h

Aug 8, 2024 · 1,204 followers View post →

Vivek Kumar

@Vivekdna · X

Example papers from our lab: Mouse Grooming https://t.co/iEDgadAUYR Mouse Pose and Gait https://t.co/DogHpPUtHD Mouse Frailty https://t.co/UOS79KDbQ7

Jun 13, 2023 · 3 likes · 1,204 followers View post →

Diego Forero MD, PhD

@daforerog · X

Stride-level analysis of mouse open field behavior using deep-learning-based pose estimation https://t.co/3OFDpfGFt0

Feb 7, 2022 · 1,596 followers View post →

RRID Robot

@RobotRrid · X

RRIDs were included in the Cell Reports paper "Stride-level analysis of mouse open field behavior…" (https://t.co/EWLrDK529v). RRIDs like this improve reproducibility in scientific research. #RRID #methodsmatter

Feb 2, 2022 · 161 followers View post →

RRID Robot

@RobotRrid · X

RRIDs were included in the Cell Reports paper "Stride-level analysis of mouse open field behavior…" (https://t.co/EWLrDK529v). We appreciate the author's support of reproducibility. #RRID #STMpublishing

Jan 17, 2022 · 161 followers View post →

robo_gwas

@robo_gwas · X

Stride-level analysis of mouse open field behavior using deep-learning-based pose estimation https://t.co/WujWkZAb1p

Jan 13, 2022 · 169 followers View post →

Psychiatric Genomics Bot

@PsychGenPapers · X

Stride-level analysis of mouse open field behavior using deep-learning-based pose estimation https://t.co/XnbaVL8RiO

Jan 13, 2022 · 1 like · 180 followers View post →

neuropsychgenpapers

@neuropsychgenp1 · X

Stride-level analysis of mouse open field behavior using deep-learning-based pose estimation https://t.co/m1oV9yiCVd https://t.co/6mkmuFXSGt

Jan 13, 2022 · 1 like · 18 followers View post →