Front Psychiatry February 2022 PMID 35185636

Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain.

Jenny L L Csecs, Valeria Iodice, Charlotte L Rae, Alice Brooke, Rebecca Simmons, Lisa Quadt, Georgia K Savage, Nicholas G Dowell, Fenella Prowse, Kristy Themelis, Christopher J Mathias, Hugo D Critchley, Jessica A Eccles

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Mentions

77
Peak: 9 in Feb 2022
across 3 sources since Feb 2022

Extended reach

241,484
potential audience

Total likes

181

Video views

396

Mentions per month

Feb 2022 – Jul 2025

Where it's discussed

  • X / Twitter70 posts
  • YouTube6 videos
  • Bluesky1 posts

AI synopsis

What people are saying

The discussions reveal a strong collective interest and agreement, with posts highlighting the significant links between hypermobility, neurodivergence, and autonomic issues, such as references to 'this study,' 'recent research,' and statements like 'this is a key study.' The tone and choice of words express enthusiasm, validation, and a drive to raise awareness across various communities.

AgreementStrong agreement

Most discussions agree with and support the findings of the research, emphasizing its relevance to conditions like autism, ADHD, and dysautonomia.

InterestHigh interest

The level of interest is high, as many comments reference specific studies, linkages to neurodivergent conditions, and ongoing research efforts.

EngagementHigh engagement

Posts demonstrate deep engagement through citing research papers, sharing personal insights, discussing implications, and advocating for awareness.

ImpactHigh impact

The conversations suggest that the article has a significant impact, influencing advocacy, clinical understanding, and public awareness of these interconnected conditions.

Abstract in brief

  • The study found that adults with neurodevelopmental conditions like ADHD and Tourette syndrome are more likely to have joint hypermobility, with prevalence rates over twice those of the general population.
  • Neurodivergent individuals also experience higher levels of autonomic dysfunction, such as orthostatic intolerance, and report more musculoskeletal pain compared to similar individuals without these conditions.
  • The findings suggest a link between connective tissue vulnerability (manifested as hypermobility) and increased psychological, autonomic, and physical symptoms in neurodivergent adults, especially among females.

Top posts

Most liked on X and Bluesky
SEDSConnective
@SEDSConnective · X

Yes we have been advocating this as the leading user led charity for many years. Here is a key study from our Patron's Dr Eccles' team on neurodivergence and pain. Keenly why burn out for autistic children and adults is often misattributed! https://t.co/smhY1H6Y7r https://t.co/wuciz1DoFF https://t.co/nki11zEc7U

Jun 3, 2024 · 33 likes · 7 shares · 5,644 followers View post →
Lucy K Wills FRSA
@LucyKWills · X

New research report showing clear links between #Neurodivergence, #hypermobility & #Dysautonomia. - further indication that #actuallyautistic people may have hidden disabilities & unmet health needs too. Thanks @BSMSMedSchool et al via @HMSACharity https://t.co/LgtTNGv5Qz

Oct 27, 2022 · 19 likes · 4 shares · 1,615 followers View post →
SEDSConnective
@SEDSConnective · X

It’s still #AutismAcceptanceMonth and awareness for those unaware symptomatic hypermobility is more than double to be an issue for autistic and other neurodivergent people than the general population ? https://t.co/smhY1H6qhT

Apr 22, 2024 · 16 likes · 5 shares · 5,644 followers View post →
Lucinda Miller
@NatureDocHealth · X

And here is the paper "Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain" @BendyBrain #autism #Neurodiversity #ADHD #Tourettes https://t.co/QXpy7H5VCr

Feb 3, 2022 · 10 likes · 1 share · 2,915 followers View post →
LePubScientifique
@LePubScientifiq · X

The Tuesday Paper - perfect to whet your appetite before our next event with @BendyBrain on Neurodivergence & Pain. Let’s find out how neurodivergent people are affected with pain and bring the knowledge back to the clinic https://t.co/Poaf3osZgi

Jun 13, 2023 · 8 likes · 3 shares · 2,229 followers View post →
LePubScientifique
@LePubScientifiq · X

We are honoured to welcome Dr Jessica Eccles (@BendyBrain) to Le Pub to delve into the fascinating realm of brain-body research & how this has linked pain to neurodivergence. Included in Le Pub Premium membership https://t.co/CoCEEdNvJ0 Paper: https://t.co/Poaf3osrqK https://t.co/C0H4vxebmx

Jun 19, 2023 · 7 likes · 2,229 followers View post →

All mentions

Jack Skiba
@jackmskiba · X

@Thomasdelvasto_ perhaps not quite shamanism as such but according to this study, there’s a relationship between hypermobility & neurodivergence: https://t.co/xD1InMFfuJ

Mar 11, 2025 · 1 like · 16 followers View post →
BendyBrain: Dr Jessica Eccles
@BendyBrain · X

@Mudling83 @SEDSConnective @CKampoureli We have studied HM and ND https://t.co/dqz5zepkcW We actually collected the data for this imaging study and the ND study a long time ago. At the point of securing ethics there were no systematic studies of HM and ND - it’s likely that these are highly overlapping with anxiety.

Feb 11, 2025 · 3 likes · 8,114 followers View post →
Random stuff.
@NinaWadcock · X

@Procrastologist @stijnnoorman https://t.co/xBAkA1hrPd

Feb 3, 2025 · 3 likes · 795 followers View post →
Noora
@gynemimesis · X

@Faustina_former I think there's a common factor here. Among autistics, 50% were hypermobile, and we know that autism is overrepresented among AGPs. And hypermobile people are way more likely to be anxious - 70% compared to 22% in the control group https://t.co/XJATfHIMWI

Dec 11, 2024 · 2 likes · 303 followers View post →
SEDSConnective
@sedsconnective.org · Bluesky

We have just few of them on our website www.sedsconnective.org but as so wide ( neurodivergence and hypermobility) this is a key one pubmed.ncbi.nlm.nih.gov/35185636/

Dec 8, 2024 View post →
BendyBrain: Dr Jessica Eccles
@BendyBrain · X

@AutisticDoctor @leaferi See https://t.co/dqz5zeoMno And https://t.co/RcNRYEklgH

Nov 5, 2024 · 8,114 followers View post →
Friedrich
@Friedri23257098 · X

Csecs JLL, Iodice V, Rae CL, Brooke A, Simmons R, Quadt L, Savage GK, Dowell NG, Prowse F, Themelis K, Mathias CJ, Critchley HD and Eccles JA (2022) Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain. Front. Psychiatry 12:786916. doi: 10.3389/fpsyt.2021.786916

Oct 23, 2024 · 535 followers View post →
22Q11 Ireland
@22Q11_Ireland · X

Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain https://t.co/xdTpTQWCIM

Oct 20, 2024 · 4,761 followers View post →
Parents Voices in Wales CIC
@PCamhs · X

Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain - PubMed ⁦@WGHealthandCare⁩ ⁦@wolfsoncentre⁩ ⁦@AutisticMindsUK⁩ #NDIP https://t.co/62nxBz2Zpa

Oct 12, 2024 · 4,954 followers View post →
BendyBrain: Dr Jessica Eccles
@BendyBrain · X

@DryRoastPeanuts @AutisticDoctor Also https://t.co/0bXboUVZUN

Jul 17, 2024 · 1 like · 8,114 followers View post →
Sara
@SaraCochrane3 · X

RT @SEDSConnective: Yes we have been advocating this as the leading user led charity for many years. Here is a key study from our Patron's…

Jun 4, 2024 · 7 shares · 3,535 followers View post →
Bonnie Southgate
@hEDSrehab · X

RT @SEDSConnective: Yes we have been advocating this as the leading user led charity for many years. Here is a key study from our Patron's…

Jun 3, 2024 · 7 shares · 1,186 followers View post →
OhTWIST.bsky.social now too
@H2OhTwist · X

RT @SEDSConnective: Yes we have been advocating this as the leading user led charity for many years. Here is a key study from our Patron's…

Jun 3, 2024 · 7 shares · 8,339 followers View post →
lightseeker22
@lightseeker22 · X

RT @SEDSConnective: Yes we have been advocating this as the leading user led charity for many years. Here is a key study from our Patron's…

Jun 3, 2024 · 7 shares · 872 followers View post →
Mary Starbuck
@MaryStarbuck3 · X

RT @SEDSConnective: Yes we have been advocating this as the leading user led charity for many years. Here is a key study from our Patron's…

Jun 3, 2024 · 7 shares · 656 followers View post →
Jane Green MBE FCCT connective
@JGjanegreenMBE · X

RT @SEDSConnective: Yes we have been advocating this as the leading user led charity for many years. Here is a key study from our Patron's…

Jun 3, 2024 · 7 shares · 5,968 followers View post →
SEDSConnective
@SEDSConnective · X

Yes we have been advocating this as the leading user led charity for many years. Here is a key study from our Patron's Dr Eccles' team on neurodivergence and pain. Keenly why burn out for autistic children and adults is often misattributed! https://t.co/smhY1H6Y7r https://t.co/wuciz1DoFF https://t.co/nki11zEc7U

Jun 3, 2024 · 33 likes · 7 shares · 5,644 followers View post →
IGC Bone Research Team
@IGCBRT · X

RT @kathrynberg_: 1/ As part of the wider hEDS-START Study, we wanted to look at diagnostic rates of various neurodivergent conditions in a…

May 23, 2024 · 3 shares · 32 followers View post →
Dervil Dockrell
@dervidock · X

RT @kathrynberg_: 1/ As part of the wider hEDS-START Study, we wanted to look at diagnostic rates of various neurodivergent conditions in a…

May 23, 2024 · 3 shares · 146 followers View post →
Kathryn Berg
@kathrynberg_ · X

1/ As part of the wider hEDS-START Study, we wanted to look at diagnostic rates of various neurodivergent conditions in a group diagnosed with hEDS/HSD, in response to a 2022 paper in which 51% of a neurodivergent population were found to be hypermobile (https://t.co/eQOFvCXXzX). https://t.co/YgEakUTFw8

May 23, 2024 · 2 likes · 3 shares · 56 followers View post →
Caroline Keep
@Ka81 · X

@LesleyABMcP @jdurran @ADHDFoundation @ADHDUKcharity And #EDS #heds happens alot. I have that mix of them. https://t.co/bS2TX4cU0f

May 10, 2024 · 2 likes · 13,534 followers View post →
hEDSErica (Barnacles)
@Barnacl3s · X

RT @SEDSConnective: It’s still #AutismAcceptanceMonth and awareness for those unaware symptomatic hypermobility is more than double to be a…

Apr 24, 2024 · 5 shares · 107 followers View post →
Red ♿️
@RedIsND · X

RT @SEDSConnective: It’s still #AutismAcceptanceMonth and awareness for those unaware symptomatic hypermobility is more than double to be a…

Apr 23, 2024 · 5 shares · 1,290 followers View post →
⚡️
@MedicallyGaslit · X

RT @SEDSConnective: It’s still #AutismAcceptanceMonth and awareness for those unaware symptomatic hypermobility is more than double to be a…

Apr 23, 2024 · 5 shares · 739 followers View post →
Grace
@gracearmagh · X

RT @SEDSConnective: It’s still #AutismAcceptanceMonth and awareness for those unaware symptomatic hypermobility is more than double to be a…

Apr 22, 2024 · 5 shares · 896 followers View post →
SEDSConnective
@SEDSConnective · X

It’s still #AutismAcceptanceMonth and awareness for those unaware symptomatic hypermobility is more than double to be an issue for autistic and other neurodivergent people than the general population ? https://t.co/smhY1H6qhT

Apr 22, 2024 · 16 likes · 5 shares · 5,644 followers View post →
SEDSConnective
@SEDSConnective · X

@Seonaidanderso2 @TS_Researcher Interesting but no mention of symptomaticHypermobility (gJH EDS ) or key cooccurring conditions like neurodivergence research ? https://t.co/smhY1H6qhT

Feb 28, 2024 · 1 like · 5,644 followers View post →
흰뺨검둥요를레히리
@amaite_ · X

Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain https://t.co/CEwFIh7rWh 이거 너무 신기하다....

Aug 20, 2023 · 1,793 followers View post →
Dr Tammy Davidson Thompson
@TammyDavidsonTh · X

@dgurdasani1 https://t.co/ZtIldVibPm Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain

Aug 18, 2023 · 878 followers View post →
Stickman Communications ltd
@stickmancrips · X

@AnnLedington Yep. Definitely a thing - and the autism plus autonomic stuff usually goes hand in hand with hypermobility. Here's a summary article of recent research: https://t.co/6qODn3TCtA

Jul 10, 2023 · 7,034 followers View post →
DrRPalmquist
@DrPalmquist · X

Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain https://t.co/jTyQ40iXga

Jun 25, 2023 · 3,168 followers View post →
LePubScientifique
@LePubScientifiq · X

We are honoured to welcome Dr Jessica Eccles (@BendyBrain) to Le Pub to delve into the fascinating realm of brain-body research & how this has linked pain to neurodivergence. Included in Le Pub Premium membership https://t.co/CoCEEdNvJ0 Paper: https://t.co/Poaf3osrqK https://t.co/C0H4vxebmx

Jun 19, 2023 · 7 likes · 2,229 followers View post →
Isobel Knight
@IsobelKnight2 · X

RT @LePubScientifiq: The Tuesday Paper - perfect to whet your appetite before our next event with @BendyBrain on Neurodivergence & Pain.…

Jun 15, 2023 · 3 shares · 7,867 followers View post →
Jay Murugavel
@JayMurugavel · X

RT @LePubScientifiq: The Tuesday Paper - perfect to whet your appetite before our next event with @BendyBrain on Neurodivergence & Pain.…

Jun 13, 2023 · 3 shares · 277 followers View post →
BendyBrain: Dr Jessica Eccles
@BendyBrain · X

RT @LePubScientifiq: The Tuesday Paper - perfect to whet your appetite before our next event with @BendyBrain on Neurodivergence & Pain.…

Jun 13, 2023 · 3 shares · 8,114 followers View post →
LePubScientifique
@LePubScientifiq · X

The Tuesday Paper - perfect to whet your appetite before our next event with @BendyBrain on Neurodivergence & Pain. Let’s find out how neurodivergent people are affected with pain and bring the knowledge back to the clinic https://t.co/Poaf3osZgi

Jun 13, 2023 · 8 likes · 3 shares · 2,229 followers View post →
SimpsonUpperLimb
@LimbSimpson · X

Important for all MSK clinicians to take onboard. Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain - PubMed https://t.co/hZzmh2Jitv

May 6, 2023 · 97 followers View post →
CHRONIC
@chronic_action · X

RT @Szyzygy2: Joint hypermobility links neurodivergence to dysautonomia and pain https://t.co/EGo1WLMOFY

Mar 26, 2023 · 1 share · 1,171 followers View post →
Szyzygy
@Szyzygy2 · X

Joint hypermobility links neurodivergence to dysautonomia and pain https://t.co/EGo1WLMOFY

Mar 26, 2023 · 7 likes · 1 share · 1,175 followers View post →
Mary Lewis
@mem_lewis · X

Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain https://t.co/aT9KjAwBST

Feb 20, 2023 · 1,444 followers View post →
The Roaring Mouse
@emmiellifluous · X

Posted this previously. Reposting in this

Feb 13, 2023 · 7 likes · 678 followers View post →
The Roaring Mouse
@emmiellifluous · X

“Joint #Hypermobility Links Neurodivergence to #Dysautonomia and Pain” https://t.co/EG1TBWQSXZ #hEDS #POTS #ActuallyAutistic #ADHD #AuDHD #TS #ChronicPain

Feb 4, 2023 · 2 likes · 678 followers View post →
Nix P
@NixP330 · X

Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain https://t.co/pAmLPiyiel

Nov 30, 2022 · 34 followers View post →
Peripheral Minds
@PeripheralMinds · X

Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain https://t.co/5lNohf4bNl

Nov 5, 2022 · 1 like · 1,570 followers View post →
Peripheral Minds
@PeripheralMinds · X

Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain https://t.co/VkOJlbitmN

Oct 30, 2022 · 1,570 followers View post →
Susan
@SusanLa69642683 · X

RT @LucyKWills: New research report showing clear links between #Neurodivergence, #hypermobility & #Dysautonomia. - further indication tha…

Oct 29, 2022 · 4 shares · 1,061 followers View post →
Dr Melanie
@MelanieWeckert · X

RT @LucyKWills: New research report showing clear links between #Neurodivergence, #hypermobility & #Dysautonomia. - further indication tha…

Oct 29, 2022 · 4 shares · 11,245 followers View post →
hypermobility.org
@HMSACharity · X

Our Lara's a bit whelmed (long day) and has made a smart pacing decision. She's nesting on a sofa with dog, so we pulled an FAQ out of the hat. Is there a link between joint hypermobility and neurodivergence? Why yes there is, here's some of the why... https://t.co/BuJCmxjqyZ https://t.co/9JZtNZq0cl

Oct 28, 2022 · 6 likes · 1 share · 11,531 followers View post →
Cheryl Iny Harris, MPH, RD
@CherylharrisRD · X

RT @LucyKWills: New research report showing clear links between #Neurodivergence, #hypermobility & #Dysautonomia. - further indication tha…

Oct 27, 2022 · 4 shares · 1,804 followers View post →
hypermobility.org
@HMSACharity · X

RT @LucyKWills: New research report showing clear links between #Neurodivergence, #hypermobility & #Dysautonomia. - further indication tha…

Oct 27, 2022 · 4 shares · 11,531 followers View post →
Lucy K Wills FRSA
@LucyKWills · X

New research report showing clear links between #Neurodivergence, #hypermobility & #Dysautonomia. - further indication that #actuallyautistic people may have hidden disabilities & unmet health needs too. Thanks @BSMSMedSchool et al via @HMSACharity https://t.co/LgtTNGv5Qz

Oct 27, 2022 · 19 likes · 4 shares · 1,615 followers View post →
Mary Doherty
@AutisticDoctor · X

@aSENDnavigator @PhysioPainAssoc Great to hear. Have you seen this fab paper by @BendyBrain & team? https://t.co/pZolagyW87

Sep 15, 2022 · 2 likes · 12,280 followers View post →
Diane Wass
@DianeWass1 · X

RT @SENDinfoBucks: https://t.co/hPunchbpm0 Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain https://t.co/AO56Ov1kax https…

Jul 8, 2022 · 1 share · 285 followers View post →
Autism and ADHD Journey
@SENDinfoBucks · X

https://t.co/hPunchbpm0 Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain https://t.co/AO56Ov1kax https://t.co/2MieQuqDsm

Jul 8, 2022 · 3 likes · 1 share · 1,660 followers View post →
Caroline Ange
@Carolineangen · X

Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain https://t.co/yNaG9nNRJa

Jun 29, 2022 · 124 followers View post →
Margie Olds
@margie_olds · X

Hmm… this is interesting. https://t.co/DPDv1vMxOL https://t.co/BOgKfdfWXI

Jun 19, 2022 · 5 likes · 1,092 followers View post →
Karyn RN
@KarynRN4 · X

Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain https://t.co/waX7L8Cicz My 15 & I are interested in the connection between neurodivergence &EDS. 15 does not have ND dx (at this point). She is an smart young lady! #MyEDSChallenge @TheEDSociety #RareDisease

May 4, 2022 · 1 like · 2,374 followers View post →
Cynthia Archer, M.D.
@YesIAmTheDoctor · X

This pearl was buried in a comment about #dysautonomia #hEDS , #neurodivergence and #pain , amongst other things including #migraine . Unifying dx? *Occam’s Razor.* Frontiers | Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain | Psychiatry https://t.co/CREqIuPaX3

Apr 29, 2022 · 2 likes · 527 followers View post →
OhTWIST.bsky.social now too
@H2OhTwist · X

RT @jan_nahlinke: @H2OhTwist @drclairetaylor @EvidenceTroll @Dan_Wyke Interesting. I know of the the pentad but wholly agree with your assu…

Apr 25, 2022 · 1 share · 8,339 followers View post →
janna
@jan_nahlinke · X

@H2OhTwist @drclairetaylor @EvidenceTroll @Dan_Wyke Interesting. I know of the the pentad but wholly agree with your assumptions here. I have EDS and Co and current being investigated for a PID. Also this article recently is v interesting https://t.co/oIMUPt1jBA.

Apr 25, 2022 · 7 likes · 1 share · 696 followers View post →
janna
@jan_nahlinke · X

@SHughesDr @drclairetaylor @npayne9000 https://t.co/oIMUPt1jBA. This paper is v interesting on this topic.

Apr 25, 2022 · 696 followers View post →
Silver Foxette
@Zekupha · X

RT @dr_todd: #Autism, #ADHD, and #Tourettesyndrome (#TS) are associated with a higher prevalence of joint hypermobility, #dysautonomia, and…

Mar 3, 2022 · 1 share · 292 followers View post →
Paul Whiteley
@PaulWhiteleyPhD · X

Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain https://t.co/J3BS8TYfQU Aside from the misnomer that is 'neurodivergence' (diverging from what?), joint hypermobility is an important feature coinciding with autism, ADHD, etc https://t.co/OzYXw2vkbp

Feb 22, 2022 · 4,984 followers View post →
ACPSEMdance
@ACPSEMdance · X

RT @LucindaNatDoc: And here is the paper "Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain" @BendyBrain #autism #Neurodiv…

Feb 3, 2022 · 1 share · 2,968 followers View post →
Lucinda Miller
@NatureDocHealth · X

And here is the paper "Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain" @BendyBrain #autism #Neurodiversity #ADHD #Tourettes https://t.co/QXpy7H5VCr

Feb 3, 2022 · 10 likes · 1 share · 2,915 followers View post →
Peripheral Minds
@PeripheralMinds · X

Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain https://t.co/fK3amaFlEI

Feb 3, 2022 · 3 likes · 1,570 followers View post →
Sue Barrett
@sue_barrett2 · X

RT @twillierod: Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain https://t.co/9oJf1U6hAt

Feb 3, 2022 · 4 shares · 265 followers View post →
Isobel Knight
@IsobelKnight2 · X

Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain https://t.co/khwKrZsJhR

Feb 2, 2022 · 3 likes · 7,867 followers View post →
Let Us Communicate - Independent SEND Support Grp
@LUC_autism · X

RT @twillierod: Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain https://t.co/9oJf1U6hAt

Feb 2, 2022 · 4 shares · 3,102 followers View post →
Graham Mead (NeuroPleb)
@twillierod · X

Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain https://t.co/9oJf1U6hAt

Feb 2, 2022 · 4 likes · 4 shares · 1,448 followers View post →
Frontiers - Psychiatry
@FrontPsychiatry · X

New Research: Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain: Objectives Autism, attention deficit hyperactivity disorder (ADHD), and tic disorder (Tourette syndrome; TS) are neurodevelopmental conditions that frequently… https://t.co/WNpmI0mjFK #Psychiatry

Feb 2, 2022 · 1 like · 16,545 followers View post →