JAAD Int March 2022 PMID 35199047

Comparing the frequency of isotretinoin-induced hair loss at <0.5-mg/kg/d versus ≥0.5-mg/kg/d dosing in acne patients: A systematic review.

Yuliya Lytvyn, Katherine McDonald, Asfandyar Mufti, Jennifer Beecker

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Mentions

12
Peak: 5 in Mar 2022
across 4 sources since Feb 2022

Extended reach

67,041
potential audience

Total likes

533

Video views

29,505

Mentions per month

Feb 2022 – Nov 2023

Where it's discussed

  • X / Twitter6 posts
  • YouTube2 videos
  • Reddit2 posts
  • News2 articles

AI synopsis

What people are saying

Participants generally show high interest in the relationship between dosage and hair loss, with phrases like 'dose-related trend' and calls for better patient information indicating engagement. The tone ranges from supportive acknowledgment to curiosity about applying these findings in real-world scenarios, reflecting moderate impact awareness. Words like 'suggests' and references to further research highlight a cautious optimism about the study’s influence.

AgreementModerate agreement

Most discussions acknowledge the findings of the systematic review, with some expressing support for the idea that higher doses are linked to increased hair loss risk.

InterestHigh interest

The majority show strong interest, as they discuss the implications for treatment decisions and highlight the relevance of dosing in acne management.

EngagementModerate engagement

Some participants delve into the methodological aspects and implications, although others simply acknowledge the results without deep analysis.

ImpactModerate impact

The overall tone suggests that the study could influence clinical practice and patient awareness, though that impact appears cautious rather than transformative.

Abstract in brief

  • This systematic review compares the frequency of hair loss in acne patients taking two different doses of isotretinoin (0.5 mg/kg/day and 0.75 mg/kg/day), finding that hair loss occurs more often at the higher dose but still affects a minority of patients.
  • The review analyzed 22 studies and noted that approximately 3.2% of patients on 0.5 mg/kg/day experienced hair loss, compared to about 5.7% at the higher dose, suggesting a dose-related trend in hair loss risk.
  • The authors recommend that doctors inform patients about the risk of hair loss before starting treatment and suggest that more high-quality research is needed to better understand the relationship between dose and hair loss safety.]

Top posts

Most liked on X and Bluesky
JAAD Journals
@JAADjournals · X

Comparing the frequency of isotretinoin-induced hair loss at <0.5-mg/kg/d versus ≥0.5-mg/kg/d dosing in acne patients: A systematic review https://t.co/fPtaeHTewn https://t.co/xLy4S7q6ru

Mar 27, 2022 · 25 likes · 6 shares · 18,531 followers View post →
أ.د.فهد السيف
@drfahad1000 · X

دراسة حديثة توضح ان معدل اصابة من يستخدم دواء الروكتان بتساقط الشعر الغير طبيعى يتراوح بين ٣-٦٪؜ و يزيد هذا الاحتمال مع زيادة الجرعة اليومية. https://t.co/pUJ8HyPaHX

Feb 24, 2022 · 3 likes · 10,703 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @JAADjournals: Comparing the frequency of isotretinoin-induced hair loss at <0.5-mg/kg/d versus ≥0.5-mg/kg/d dosing in acne patients: A…

Mar 27, 2022 · 6 shares · 6,709 followers View post →
Kevin McElwee
@ResearchHair · X

RT @JAADjournals: Comparing the frequency of isotretinoin-induced hair loss at <0.5-mg/kg/d versus ≥0.5-mg/kg/d dosing in acne patients: A…

Mar 27, 2022 · 6 shares · 883 followers View post →
Aline Garcia Arteaga
@alinearteaga · X

RT @JAADjournals: Comparing the frequency of isotretinoin-induced hair loss at <0.5-mg/kg/d versus ≥0.5-mg/kg/d dosing in acne patients: A…

Mar 27, 2022 · 6 shares · 639 followers View post →
Joaquim Junior
@jxsjunior · X

RT @JAADjournals: Comparing the frequency of isotretinoin-induced hair loss at <0.5-mg/kg/d versus ≥0.5-mg/kg/d dosing in acne patients: A…

Mar 27, 2022 · 6 shares · 12 followers View post →

All mentions

Aline Garcia Arteaga
@alinearteaga · X

RT @JAADjournals: Comparing the frequency of isotretinoin-induced hair loss at <0.5-mg/kg/d versus ≥0.5-mg/kg/d dosing in acne patients: A…

Mar 27, 2022 · 6 shares · 639 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @JAADjournals: Comparing the frequency of isotretinoin-induced hair loss at <0.5-mg/kg/d versus ≥0.5-mg/kg/d dosing in acne patients: A…

Mar 27, 2022 · 6 shares · 6,709 followers View post →
Kevin McElwee
@ResearchHair · X

RT @JAADjournals: Comparing the frequency of isotretinoin-induced hair loss at <0.5-mg/kg/d versus ≥0.5-mg/kg/d dosing in acne patients: A…

Mar 27, 2022 · 6 shares · 883 followers View post →
Joaquim Junior
@jxsjunior · X

RT @JAADjournals: Comparing the frequency of isotretinoin-induced hair loss at <0.5-mg/kg/d versus ≥0.5-mg/kg/d dosing in acne patients: A…

Mar 27, 2022 · 6 shares · 12 followers View post →
JAAD Journals
@JAADjournals · X

Comparing the frequency of isotretinoin-induced hair loss at <0.5-mg/kg/d versus ≥0.5-mg/kg/d dosing in acne patients: A systematic review https://t.co/fPtaeHTewn https://t.co/xLy4S7q6ru

Mar 27, 2022 · 25 likes · 6 shares · 18,531 followers View post →
أ.د.فهد السيف
@drfahad1000 · X

دراسة حديثة توضح ان معدل اصابة من يستخدم دواء الروكتان بتساقط الشعر الغير طبيعى يتراوح بين ٣-٦٪؜ و يزيد هذا الاحتمال مع زيادة الجرعة اليومية. https://t.co/pUJ8HyPaHX

Feb 24, 2022 · 3 likes · 10,703 followers View post →