The overall tone emphasizes the robustness and importance of the findings, with discussions highlighting specific affected brain areas like the orbitofrontal cortex, and noting that effects occur even in mild cases, which underscores the broader impact. Words like 'longitudinal effects,' 'debilitating brain damage,' and references to peer-reviewed sources reflect serious, detailed engagement and indicate that the community perceives this study as highly significant for understanding COVID-19's neurological consequences.
AgreementStrong agreement
Most discussions strongly support the connection between COVID-19 and brain changes, citing the study as solid evidence.
InterestHigh interest
Posts consistently show high interest, referencing longitudinal data, specific brain regions affected, and implications for health and behavior.
EngagementHigh engagement
Many comments delve into scientific details, peer-reviewed studies, and potential health impacts, indicating deep engagement.
ImpactHigh impact
Widespread references to the research's implications for public health, brain health, and long-term effects suggest a high impact on societal awareness and policy debates.
Abstract in brief
The study found that individuals infected with SARS-CoV-2 showed significant brain changes, including reduced grey matter thickness and tissue contrast in specific areas like the orbitofrontal cortex and parahippocampal gyrus, along with a decrease in overall brain size and cognitive decline.
These changes were observed even in mild COVID-19 cases, not just hospitalized patients, indicating that SARS-CoV-2 might cause brain abnormalities across a broader spectrum of severity.
The findings suggest these brain effects could result from the virus spreading through olfactory pathways or neuroinflammatory processes, but more research is needed to determine if these changes are reversible or long-lasting.]
Dec 28, 2022 · 29 likes · 6 shares · 213,293 followersView post →
R
realtimaier
@realtimaier · X
@ahandvanish Here is a study published in “Nature” in Spring 2022.
“SARS-CoV-2 is associated with changes in brain structure in UK Biobank”
• Reduction in grey matter thickness
• Tissue damage in primary olfactory cortex
• Reduction in global brain size
https://t.co/Dxkni0Q7V0
Aug 18, 2022 · 18 likes · 8 shares · 772 followersView post →
SARS-CoV-2 is associated with changes in brain structure in UK. 1) a greater reduction in grey matter thickness and tissue contrast in the orbitofrontal cortex and parahippocampal gyrus; https://t.co/Nbfk1faVj9
This episode discusses gut problems experienced by Long Covid sufferers, focusing on treatments, management, and expected outcomes. Dr. Tim Robinson shares insights from his extensive clinical experience in Long Covid…
This episode discusses headaches experienced by Long Covid sufferers and explores brain changes associated with SARS-CoV-2 infection, including structural brain alterations even in mild cases, highlighting the…
This episode discusses Mast Cell Activation Syndrome as experienced by Long Covid sufferers, covering symptoms, assessment, diagnosis, causes, treatments, recovery timelines, and outcomes, with insights from Dr. Tim…
This episode discusses the neurological effects of COVID-19, including brain structure changes such as reduced grey matter and overall brain size, even in mild cases. Findings suggest potential long-term impacts on…
This episode discusses headache in Long Covid, covering symptoms, diagnosis, causes, and brain changes associated with SARS-CoV-2 infection, including impacts on brain structure observed even in mild cases. Further…
This episode discusses headache experienced by Long Covid sufferers, focusing on treatments, management, and outcomes, with insights from Dr. Tim Robinson, a Long Covid expert and researcher in NHS services.
@jeremyjhowes @ABridgen Covid brain damage before vaccines were released:
SARS-CoV-2 is associated with changes in brain structure in UK Biobank
“each individual in our cohort was infected between the months of March 2020 and April 2021”
https://t.co/qtNwCmTJiW
SARS-CoV-2 is associated with changes in brain structure in UK. 1) a greater reduction in grey matter thickness and tissue contrast in the orbitofrontal cortex and parahippocampal gyrus; https://t.co/Nbfk1faVj9
Aug 31, 2025 · 62 likes · 20 shares · 7,232 followersView post →
S
Sass
@sasswashere · X
@MarkJCarney @INTERPOL_CBRNE @rcmpgrcpolice @csiscanada @OCSWSSW @CanPaedSociety @UN @UNHumanRights @CIJ_ICJ “SARS-CoV-2 is associated with changes in brain structure in UK Biobank.”
This has been KNOWN since 2022.
https://t.co/s9vlAqPpOm
Aug 16, 2025 · 4 likes · 8 shares · 6,029 followersView post →
EE
Entropic Equilibrium
@EntropicEq · X
SARS-CoV-2 is associated with changes in brain structure in UK Biobank
2x MRI
n=785
401cases, 384controls
51-81y
“Importantly, these imaging & cognitive longitudinal effects were still observed after excluding the 15 patients who had been hospitalised.”
https://t.co/ExEFSBVkK1
@cryptokyle_33 @VenZenix @JackHadfield14 Heart Problems After Covid-19 https://t.co/1N3Dvvk2iY
SARS-CoV-2 is associated with changes in brain structure in UK Biobank | Nature https://t.co/LzXamcBBkA
Even Mild COVID-19 May Change the Brain | Infectious Diseases | JAMA | JAMA Network https://t.co/M1je2fWpnc
Jul 12, 2025 · 1 like · 1,623 followersView post →
S
SpaS
@sipanne · X
SARS-CoV-2 is associated with changes in brain structure in UK Biobank | Nature https://t.co/mOOULhWpWP
SARS-CoV-2 is associated with changes in brain structure in UK Biobank | Nature https://t.co/98Imcu6ziX
Jun 27, 2025 · 1 like · 1,094 followersView post →
A
Ariti
@LedenUnor · X
@vicormcu @RepRobinKelly Nah. I tested my blood O2 with and without a mask. No difference. But some of the impact of covid on the brain was evidenced before the vaccine was available. https://t.co/kFpWGsFLuN
RT @sasswashere: @csiscanada @rcmpgrcpolice @JustinTrudeau @DLeBlancNB @INTERPOL_CBRNE 2022
“SARS-CoV-2 is associated with changes in brai…
Jun 8, 2025 · 5 shares · 6,029 followersView post →
ES
empathy1st.bsky.social
@empathy1st.bsky.social · Bluesky
Covid is something you want to protect your kids from.
Get them vaxed now while you still can.
Who knows what will happen with this new admin that thinks swimming in sewage overflow is a good idea.
"SARS-CoV-2 is associated with changes in brain structure"
pmc.ncbi.nlm.nih.gov/articles/PMC...
@ChefGruel @TimmyGeezus Covid can infect the brain - the UK brain bio bank study compared pre and post covid imaging and evidences that Covid changes the brain. https://t.co/kFpWGsFdFf
RT @sasswashere: @csiscanada @rcmpgrcpolice @JustinTrudeau @DLeBlancNB @INTERPOL_CBRNE 2022
“SARS-CoV-2 is associated with changes in brai…
Feb 5, 2025 · 5 shares · 6,029 followersView post →
S
Sass
@sasswashere · X
@csiscanada @rcmpgrcpolice @JustinTrudeau @DLeBlancNB @INTERPOL_CBRNE 2022
“SARS-CoV-2 is associated with changes in brain structure in UK Biobank.”
https://t.co/s9vlAqPpOm
Jan 31, 2025 · 1 like · 5 shares · 6,029 followersView post →
JT
Joanna Teglund
@JoannaTeglund · X
RT @ErinSandersNP: @DaniBeckman References:
SARS-CoV-2 infection and persistence in the human body and brain at autopsy
https://t.co/VTMBj…
Jan 8, 2025 · 10 shares · 8,604 followersView post →
DC
Dr. Paul Cottrell
@dr_cottrell · X
SARS-CoV-2 is associated with changes in brain structure in UK Biobank
https://t.co/rMK3K9bB4t
Jan 2, 2025 · 4 likes · 10,323 followersView post →
H
Hannelore
@msremagen · X
RT @danwalker9999: @Sheep_in_fog 2022 longitudinal study of pre- and post-COVID MRI scans in a group of patients aged 51-81 years (mean ~ 6…
@JamesThrot @ellenlovesrich UK Biobank scans & cognitive testing pre-and-post COVID in 785 ppl. (401 ppl w/C19; rest were controls who also had had paired scans & testing. The "recovered" Covid pop had deleterious changes in their second scans, & ⬇️ cognitive performance as well.
https://t.co/qMyQ9Ja7Wj
Hi Dr. Smith, you were an author on ‘SARS-CoV-2 is associated with changes in brain structure in UK Biobank.’ I believe it’s a longitudinal study—are there plans for the next set of brain scans? If so, when might they be available? Hope this isn’t crossing any boundaries. Respectfully asking.
@KaMillYon1 @BehizyTweets @cenkuygur "SARS-CoV-2 is associated with changes in brain structure"
It's hard to overstate how dumb you'd need to be to encourage people to risk exposing themselves to brain damage but that's literally what you're advocating.
https://t.co/UGX2L2K3hN
1/2
SARS-CoV-2 is associated with changes in brain structure in UK Biobank | Nature - Douaud &a - 05 2022
785 Menschen
51 - 81 Jahre alt
401 mit C19 zwischen den beiden Aufnahmen
die folgenden Befunde alle relativ zu den Alters-verschlechterungen:weniger graue Masse im
@fascinatorfun @ChristosArgyrop had paired scans & cognitive testing. The "recovered" Covid pop had deleterious structural & functional changes in their second scans, & had deteriorated on their cognitive test performance as well.
https://t.co/qMyQ9J9A6L
SARS-CoV-2 is associated with changes in brain structure in UK Biobank | Nature
Imaging & cognitive longitudinal effects were still observed after excluding the 15 patients were hospitalised.
No wonder we’re seeing an increase in shitty behaviour! https://t.co/48PD1PRdb2
Sep 6, 2024 · 1 like · 2 shares · 573 followersView post →
SARS-CoV-2 is associated with changes in brain structure
"Changes in markers of tissue damage in regions functionally-connected to the primary olfactory cortex"
"Greater reduction in global brain size."
"Degenerative spread of the disease via olfactory pathways"
"greater
RT @bledwine: Frontal and temporal lobe damage associated with disinhibition SARS-CoV-2 is associated with changes in brain structure in UK…
Jun 29, 2024 · 1 share · 1,992 followersView post →
TK
This Salemite survived Kancamagus
@bledwine · X
Frontal and temporal lobe damage associated with disinhibition SARS-CoV-2 is associated with changes in brain structure in UK Biobank | Nature https://t.co/dHMPiJYuNl
Jun 29, 2024 · 1 like · 1 share · 3,877 followersView post →
JS
Jim Earl, jimearl.bsky.social
@jimearl666 · X
Jimmy's had covid 3 times:
Cortical Grey matter volume depletion links to neurological sequelae in post COVID-19 “long haulers”
https://t.co/9plw6I4xow
Loss of brain tissue: SARS-CoV-2 is associated with changes in brain structure in UK Biobank.
https://t.co/PSyDhk0w95 https://t.co/BeoWknAZAC
Jun 19, 2024 · 3 likes · 4,935 followersView post →
JS
Jim Earl, jimearl.bsky.social
@jimearl666 · X
@MNajeddine @jimmy_dore Jimmy's had covid 3 times:
Cortical Grey matter volume depletion links to neurological sequelae in post COVID-19 “long haulers”
https://t.co/9plw6I4xow
Loss of brain tissue: SARS-CoV-2 is associated with changes in brain structure in UK Biobank.
https://t.co/PSyDhk0w95
@Decidingfactor1 @DailyJLee @lorrain_fr51006 I did, I just couldn’t find one that said bluntly that 100% of
Covid cases had brain damage. Closest I came was this: https://t.co/pxv6AFucJP
Nature: SARS-CoV-2 is associated with changes in brain structure in UK Biobank: There is strong evidence of brain-related abnormalities in COVID-19. However, it remains unknown whether the impact of SARS-CoV-2 infection can be detected in milder cases, and whether this can reveal possible…
Douaud, G., Lee, S., Alfaro-Almagro, F. et al. SARS-CoV-2 is associated with changes in brain structure in UK Biobank. Nature 604, 697–707 (2022). https://t.co/2IvpIQTzFh
RT @danwalker9999: @Sheep_in_fog 2022 longitudinal study of pre- and post-COVID MRI scans in a group of patients aged 51-81 years (mean ~ 6…
Dec 14, 2023 · 2 shares · 6,263 followersView post →
CG
Colleen Griffith
@Griffith17431 · X
RT @DavidJoffe64: Been demonstrated for awhile...
The UK study was one of the best.
https://t.co/DdyWCtjiwm
Nov 23, 2023 · 5 shares · 948 followersView post →
TL
Terry Art Ó Laoghaire
@yabbietol · X
RT @DavidJoffe64: Been demonstrated for awhile...
The UK study was one of the best.
https://t.co/DdyWCtjiwm
Nov 23, 2023 · 5 shares · 1,798 followersView post →
N
Narelle
@narelleford · X
RT @DavidJoffe64: Been demonstrated for awhile...
The UK study was one of the best.
https://t.co/DdyWCtjiwm
Nov 23, 2023 · 5 shares · 5,212 followersView post →
PD
Peter Davidson
@petedavo_au · X
RT @DavidJoffe64: Been demonstrated for awhile...
The UK study was one of the best.
https://t.co/DdyWCtjiwm
Nov 23, 2023 · 5 shares · 1,000 followersView post →
DF
David Joffe MB BS (Hons), PhD, FRACP
@DavidJoffe64 · X
Been demonstrated for awhile...
The UK study was one of the best.
https://t.co/DdyWCtjiwm https://t.co/4q9tEiJGVI
Nov 23, 2023 · 11 likes · 5 shares · 17,983 followersView post →
DW
Daniel A. Walker
@danwalker9999 · X
@Sheep_in_fog 2022 longitudinal study of pre- and post-COVID MRI scans in a group of patients aged 51-81 years (mean ~ 60 years).
Douaud et al. 2022. SARS-CoV-2 is associated with changes in brain structure in UK Biobank.
https://t.co/5Sp5w1RkDx https://t.co/DolXmnQNIu
Nov 2, 2023 · 8 likes · 2 shares · 1,791 followersView post →
MS
@marcusfitzsimons.bsky.social Woke Green Socialist
@MarcusFitzsimon · X
@pot8um @1goodtern to be fair, covid is known to cause changes in the brain, which the West is taking no action to ascertain
where brain scans ARE performed, the following is found
diagnoses occur based on symptoms, impacts & effects, & behaviour / ability to concentrate
https://t.co/PCmUCRFnGL https://t.co/MLOekih8Iw
Oct 30, 2023 · 13 likes · 1 share · 19,093 followersView post →
A
AmiableSharpen
@AmiableSharpen · X
Thanks for the reminder, but two pet peeves:
1) Articles with questions pretending to be titles and
2) No link to the exact reference they are discussing.
I think they are talking about this article:
https://t.co/KZikkSZhsn https://t.co/B5pHtbkgj6
RT @sasswashere: https://t.co/s9vlAqPpOm causing brain damage, cognitive decline. Do I have to repost all of the peer reviewed medial journ…
Jan 17, 2023 · 4 shares · 6,029 followersView post →
S
Sass
@sasswashere · X
RT @sasswashere: https://t.co/s9vlAqPpOm you’re also causing BRAIN DAMAGE to kids, public. But you care about mental health right? IN SCHO…
Jan 12, 2023 · 1 share · 6,029 followersView post →
S
Sass
@sasswashere · X
https://t.co/s9vlAqPpOm you’re also causing BRAIN DAMAGE to kids, public. But you care about mental health right? IN SCHOOLS to kids. And THE Vector out. You don’t want this to end, you’re causing it
Jan 12, 2023 · 1 like · 1 share · 6,029 followersView post →
Dec 28, 2022 · 29 likes · 6 shares · 213,293 followersView post →
DD
Dra. Julia Salinas Dücker
@juliasalinas · X
@Roberto31252452 aqui la liga al articulo completo:
Douaud, G., Lee, S., Alfaro-Almagro, F. et al. SARS-CoV-2 is associated with changes in brain structure in UK Biobank. Nature 604, 697–707 (2022). https://t.co/WunrokiukK
Douaud, G., Lee, S., Alfaro-Almagro, F. et al. SARS-CoV-2 is associated with changes in brain structure in UK Biobank. Nature 604, 697–707 (2022). https://t.co/pCsFPCUBgJ
@aysiati @Robert83563198 @Karl_Lauterbach Nicht reingeschaut?
Schau mal die Quellenangaben im Link.
[1] Douaud G, Lee S, Alfaro-Almagro F et al. SARS-CoV-2 is associated with changes in brain structure in UK Biobank. Nature 2022 Mar 7. doi: 10.1038/s41586-022-04569-5. Online ahead of print.
ist also peer-reviewed
RT @realtimaier: @ahandvanish Here is a study published in “Nature” in Spring 2022.
“SARS-CoV-2 is associated with changes in brain struct…
Aug 18, 2022 · 8 shares · 232 followersView post →
JW
Justine Wellens
@wellens_justine · X
RT @realtimaier: @ahandvanish Here is a study published in “Nature” in Spring 2022.
“SARS-CoV-2 is associated with changes in brain struct…
Aug 18, 2022 · 8 shares · 254 followersView post →
J
JSwaine
@jillian_swaine · X
RT @realtimaier: @ahandvanish Here is a study published in “Nature” in Spring 2022.
“SARS-CoV-2 is associated with changes in brain struct…
Aug 18, 2022 · 8 shares · 1,992 followersView post →
PS
PF Anderson @pfanderson@disabled.social
@pfanderson · X
RT @realtimaier: @ahandvanish Here is a study published in “Nature” in Spring 2022.
“SARS-CoV-2 is associated with changes in brain struct…
Aug 18, 2022 · 8 shares · 10,772 followersView post →
MC
@mellenoweth@federate.social Carol Clarke
@mellenoweth · X
RT @realtimaier: @ahandvanish Here is a study published in “Nature” in Spring 2022.
“SARS-CoV-2 is associated with changes in brain struct…
Aug 18, 2022 · 8 shares · 1,124 followersView post →
D
DocValerie
@Doc_Valerie · X
RT @realtimaier: @ahandvanish Here is a study published in “Nature” in Spring 2022.
“SARS-CoV-2 is associated with changes in brain struct…
Aug 18, 2022 · 8 shares · 2,181 followersView post →
CG
Colleen Griffith
@Griffith17431 · X
RT @realtimaier: @ahandvanish Here is a study published in “Nature” in Spring 2022.
“SARS-CoV-2 is associated with changes in brain struct…
Aug 18, 2022 · 8 shares · 948 followersView post →
R
realtimaier
@realtimaier · X
@ahandvanish Here is a study published in “Nature” in Spring 2022.
“SARS-CoV-2 is associated with changes in brain structure in UK Biobank”
• Reduction in grey matter thickness
• Tissue damage in primary olfactory cortex
• Reduction in global brain size
https://t.co/Dxkni0Q7V0
Aug 18, 2022 · 18 likes · 8 shares · 772 followersView post →
hedef alıyor, nöronlarda membran intakt olsa da olfaktör reseptör düzeyleri azalmakta ve nükleer mimaride de değişimler izlenmekte. Ayrıca İngiltere 785 kişide yapılan çalışmada koku ile ilgili kortikal bölgelerdeki gri cevher kaybı gösterilmişti.
https://t.co/z6j3qhgBpB https://t.co/6IAoMiEZUJ
RT @Rozmelliott: https://t.co/9uTPsMg68e wear a mask
May 31, 2022 · 1 share · 4,642 followersView post →
RE
Rosalind Elliott
@Rozmelliott · X
https://t.co/9uTPsMg68e wear a mask
May 29, 2022 · 5 likes · 1 share · 395 followersView post →
JK
Jay Kusnetz
@jayrtfm · X
@SadlyItsBradley Up until 2021 I did not give much credence to SETI's self inflicted "great filter" explanation for the current results of the Drake Equation, but now I've reconsidered. Seriously, since long term effects are still mostly unknown, best not taking chances. https://t.co/rD2xjmWT7x
2/N "[... significant longitudinal effects when comparing the two groups, including (1) greater reduction in grey matter thickness and tissue contrast in the orbitofrontal cortex & parahippocampal gyrus; (2) greater changes in markers of tissue damage...]"
https://t.co/LPz2XE9v0d
May 18, 2022 · 1 like · 2,601 followersView post →
@BoobyJargon @StormyAutistic @ZakMcclintock @morgan_sung @TaylorLorenz Yes. Google exists, but since the MD in your screen name is only for show, I share now one of many examples. https://t.co/s65Ef56WZO https://t.co/ASShDYeYSM
Christoph Arthofer — Oxford University Centre for Integrative ...
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... 10.1038/s41398-024-03108-2, https: //www.nature.com/articles/s41398-024 ... com/articles/s41586-022-04569-5. Scans reveal how Covid may change the brain.
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org/10.1038/s41586-022-04569-5 https://www.nature. com/articles/s41586-022-04569-5#citeas Текст: Шахматова О.О. Больше новостеи и информации о ФГБУ «НМИЦ ...
Estudos como este são importantes formas de sedimentarmos cada vez mais este conhecimento. DOI: https://doi.org/10.1038/s41586-022-04569-5 #neurociencia # ...
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