Biol Psychol April 2022 PMID 35271957

Amygdala-driven apnea and the chemoreceptive origin of anxiety.

Justin S Feinstein, Dylan Gould, Sahib S Khalsa

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Peak: 6 in Feb 2024

across 3 sources since Mar 2022

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What people are saying

Discussions highlight the article’s suggestion that the amygdala influences breathing and anxiety through interoceptive processes, with posts referencing models like 'AiA' and mentioning studies from 2011 and 2015, reflecting ongoing scientific curiosity and recognition of its potential implications for mental health research. The tone varies from supportive to inquisitive, emphasizing the importance and innovative nature of the findings.

AgreementModerate agreement

Most discussions acknowledge the novel link between the amygdala, breathing, and anxiety, showing general support for the article's findings.

InterestHigh interest

The posts demonstrate high curiosity, with mentions of models like AiA and references to studies and theories, indicating strong engagement with the topic.

EngagementModerate engagement

While some posts briefly mention the research, others delve into its implications and theoretical models, reflecting moderate analytical engagement.

ImpactModerate impact

The discussions suggest the research has potential significance for understanding mental health issues, although the overall impact remains somewhat speculative at this stage.

Abstract in brief

The article discusses how recent findings challenge traditional views of the amygdala's role in fear and anxiety, suggesting it may also be involved in initiating apnea (cessation of breathing) and modulating CO2 sensitivity.
Studies show paradoxical results, such as patients with amygdala lesions experiencing excessive fear, anxious patients having smaller amygdalae with heightened CO2 sensitivity, and epilepsy patients showing apnea following amygdala stimulation without awareness.
The authors propose a model called Apnea-induced Anxiety (AiA), where amygdala activation causes unconscious apnea episodes, leading to CO2 spikes that provoke fear and anxiety, potentially explaining the chronic nature of anxiety disorders through interoceptive processes related to breathing and homeostasis.]

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All mentions

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Amygdala's Role in Apnea and Anxiety Mechanisms

This video explores how the amygdala may trigger unconscious apnea episodes in response to perceived threats, leading to increased carbon dioxide levels and anxiety, supporting the model of Apnea-induced Anxiety (AiA).

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