RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction in mortality (HR 0.71, 95% CI 0.49-1.03), and statistically significant improvement in LVEF, QoL and 6MWT in the ablation arm https://t.co/JO4ghZqwji
Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients With Heart Failure and Atrial Fibrillation: Results from the RAFT-AF trial.
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Mar 2022 – Aug 2025Where it's discussed
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X / Twitter92 posts
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AI synopsis
What people are saying
Several discussions reference the trial's early termination due to perceived futility, highlighting a sense of disappointment or skepticism. Phrases like 'not much has changed' and 'similar outcomes' emphasize a critical view on the ablation versus rate control debate. The nuanced tone illustrates a blend of expectation and caution, reflecting the complexity and evolving nature of treatment practices in heart failure patients.
The discussions reveal mixed reactions regarding the trial's findings, with some seeing merit in its conclusions while others express disappointment.
Participants show moderate interest, questioning implications and contextualizing the findings within existing research.
There are instances of deeper analysis, as some commenters reference specific outcomes and trends from the trial's data.
Overall, users perceive a moderate impact of the trial on future clinical practices, with varying opinions on its significance.
Abstract in brief
- The RAFTAF trial compared ablation-based rhythm control with rate control in heart failure patients with atrial fibrillation (AF).
- The trial included 411 patients and aimed to improve clinical outcomes, with the primary outcome involving all-cause mortality and heart failure events.
- The study was halted early due to a lack of benefit, showing no significant difference in primary outcomes, although secondary measures indicated improvements in left ventricular function and quality of life for the ablation group.
Top posts
Most liked on X and BlueskyRandomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients with Heart Failure and Atrial Fibrillation: results from the RAFT-AF trial https://t.co/6USscnP9Vi @AnthonyTang6 @EPjeff17 @CHRS_SCR @CANetChat
Thank you for featuring our paper. We believe that the findings also resonate well with the results from the RAFT-AF trial (https://t.co/qjoeGXYiWJ). Very much looking forward to further progress in this area of research! https://t.co/p3aQBqKtnU
NYHA2-3の心房細動(high burden PAF&PerAF)LVEFも6割程度が <35%のTable1 このような中~高リスク患者であれば、アブレーション治療のほうが、composite (mortality % HF admission)では有意かと思っていたので少し驚き https://t.co/zd4JpvQoO8
#OriginalResearch: In the #RAFTAF #RCT, there was
RAFT-AF(サブ解析) EF<45% https://t.co/YkfQ5C4TiC #EP大学
All mentions
New Insights on Atrial Fibrillation and Treatment Strategies
This week, John Mandrola MD discusses three key aspects of the recent AF guidelines, emphasizing early rhythm-control therapy's potential to reduce cardiovascular risks. Join us for an in-depth analysis of the latest…
Ablation vs Rate Control in Heart Failure with Atrial Fibrillation
This podcast discusses the RAFT-AF trial, which compared ablation-based rhythm control versus rate control in heart failure patients with atrial fibrillation. While the study showed no significant differences in primary…
心不全および心房細動患者におけるアブレーションに基づくリズムコントロールとレートコントロールのランダム化比較試験:RAFT-AF試験の結果 https://t.co/abATesIeha
RT @Crypto1835: RAFT-AF(サブ解析) EF<45% https://t.co/YkfQ5C4TiC #EP大学
RAFT-AF(サブ解析) EF<45% https://t.co/YkfQ5C4TiC #EP大学
RT @jsenior64: Finalmente, otro estudio podría darnos la respuesta, siempre y cuando reforzara los hallazgos del CASTLE HF, sin embargo pas…
Finalmente, otro estudio podría darnos la respuesta, siempre y cuando reforzara los hallazgos del CASTLE HF, sin embargo pasó todo lo contrario. Si miran la curva de mortalidad se darán cuenta que son similares hasta los dos años y luego logran separarse. https://t.co/9V6EYg51yn
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
New2Trip: Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients w/ Heart Failure & Atrial Fibrillation: Results from RAFT-AF trial https://t.co/kdjMk2mDhu
New2Trip: Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients w/ Heart Failure & Atrial Fibrillation: Results from RAFT-AF trial https://t.co/YirSZyk0Lb
New2Trip: Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients w/ Heart Failure & Atrial Fibrillation: Results from RAFT-AF trial https://t.co/YirSZyk0Lb
New2Trip: Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients w/ Heart Failure & Atrial Fibrillation: Results from RAFT-AF trial https://t.co/kdjMk2mDhu
RT @sk2798: Thank you for featuring our paper. We believe that the findings also resonate well with the results from the RAFT-AF trial (htt…
Thank you for featuring our paper. We believe that the findings also resonate well with the results from the RAFT-AF trial (https://t.co/qjoeGXYiWJ). Very much looking forward to further progress in this area of research! https://t.co/p3aQBqKtnU
New2Trip: Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients w/ Heart Failure & Atrial Fibrillation: Results from RAFT-AF trial https://t.co/YirSZyk0Lb
New2Trip: Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients w/ Heart Failure & Atrial Fibrillation: Results from RAFT-AF trial https://t.co/kdjMk2mDhu
New2Trip: Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients w/ Heart Failure & Atrial Fibrillation: Results from RAFT-AF trial https://t.co/YirSZyk0Lb
New2Trip: Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients w/ Heart Failure & Atrial Fibrillation: Results from RAFT-AF trial https://t.co/YirSZyk0Lb
New2Trip: Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients w/ Heart Failure & Atrial Fibrillation: Results from RAFT-AF trial https://t.co/kdjMk2mDhu
⬇️本文はこちらから https://t.co/KDWVDcVz3s
2 min Cardiology(臨床論文、担当:佐藤宏行) Randomized ablation-based rhythm control versus rate-control trial in patients with heart failure and atrial fibrillation : Results from the RAFT-AF trial Circulation 2022, June 7. #Cardiology
RT @RevistaMFSamfyc: Ensayo aleatorizado de ablación según ritmo frente a según frecuencia en pacientes con insuficiencia cardiaca y fibril…
Ensayo aleatorizado de ablación según ritmo frente a según frecuencia en pacientes con insuficiencia cardiaca y fibrilación auricular: resultados del ensayo RAFT-AF https://t.co/VB9ZZCb76u PMID 35313733
Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients With Heart Failure and Atrial Fibrillation: Results from the RAFT-AF trial https://t.co/hub3GwolX6
RT @CampusArritmias:
Trending on #ReadbyQxMD. The RAFT-AF trial from @CircAHA is being hotly discussed given it's possible impact on future practice and guidelines. Check it out via the link below. https://t.co/eZvEF89KNZ #CardioTwitter #ACC22 https://t.co/Rhvdo0TiS8
RT @CircAHA: #OriginalResearch: In the #RAFTAF #RCT, there was
RT @CircAHA: #OriginalResearch: In the #RAFTAF #RCT, there was
RT @CircAHA: #OriginalResearch: In the #RAFTAF #RCT, there was
RT @CircAHA: #OriginalResearch: In the #RAFTAF #RCT, there was
RT @CircAHA: #OriginalResearch: In the #RAFTAF #RCT, there was
RT @CircAHA: #OriginalResearch: In the #RAFTAF #RCT, there was
#OriginalResearch: In the #RAFTAF #RCT, there was
Some striking features: high procedure-related complications (11%) even though in top centres. Took 6 years to recruit. Circulation 2022 https://t.co/pnq6mNjGYD
RAFT-AF published on line: no effect of AF ablation in HF on all-cause mortality + all HF events. Circulation 2022 https://t.co/pnq6mNjGYD
Strict rate control compared well to rhythm control in AF+HF; maybe lenient rates (RACE-II) not best Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients with Heart Failure and Atrial Fibrillation: Results from the RAFT-AF trial https://t.co/tJcY6BvdB7
https://t.co/qnev86wyet
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
RT @CampusArritmias:
RT @CampusArritmias:
RT @CampusArritmias:
Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients with Heart Failure and Atrial Fibrillation: Results from the RAFT-AF trial https://t.co/biM5QXrqmm
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
RT @Yuki_Sahashi: NYHA2-3の心房細動(high burden PAF&PerAF)LVEFも6割程度が <35%のTable1 このような中~高リスク患者であれば、アブレーション治療のほうが、composite (mortality % HF admi…
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
Ablación en pacientes con FA y falla cardiaca detenido por futilidad. No impacta desenlace primario, aunque si algunos subrogados. https://t.co/9V6EYg51yn
RT @Yuki_Sahashi: NYHA2-3の心房細動(high burden PAF&PerAF)LVEFも6割程度が <35%のTable1 このような中~高リスク患者であれば、アブレーション治療のほうが、composite (mortality % HF admi…
Results from the RAFT-AF trial: EF, functional capacity, life quality improves but not all cause mortality and HF measures https://t.co/ISWIcJGDDE
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
RT @ratika_parkash: Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients with Heart Failure and Atrial Fibrillati…
RT @ratika_parkash: Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients with Heart Failure and Atrial Fibrillati…
RT @ratika_parkash: Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients with Heart Failure and Atrial Fibrillati…
RT @ratika_parkash: Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients with Heart Failure and Atrial Fibrillati…
RT @ratika_parkash: Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients with Heart Failure and Atrial Fibrillati…
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
RT @ratika_parkash: Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients with Heart Failure and Atrial Fibrillati…
Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients with Heart Failure and Atrial Fibrillation: Results from the RAFT-AF trial from Canada
NYHA2-3の心房細動(high burden PAF&PerAF)LVEFも6割程度が <35%のTable1 このような中~高リスク患者であれば、アブレーション治療のほうが、composite (mortality % HF admission)では有意かと思っていたので少し驚き https://t.co/zd4JpvQoO8
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
RT @ratika_parkash: Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients with Heart Failure and Atrial Fibrillati…
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
RT @ratika_parkash: Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients with Heart Failure and Atrial Fibrillati…
@Dominik_Linz @FH_Verbrugge @YMareev @FudimMarat @VKutyifa @AndreasGevaert @F_dalgaard @SolovevaAnzhela @DrMikeDrozd @MihaiTrofenciuc And things will only fall further apart between HF and EP… https://t.co/WUflhx0q3O https://t.co/4gWdmr6bBp
Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients with Heart Failure and Atrial Fibrillation: Results from the RAFT-AF trial https://t.co/0sWpKuGB0X
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
RT @ratika_parkash: Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients with Heart Failure and Atrial Fibrillati…
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
RT @ratika_parkash: Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients with Heart Failure and Atrial Fibrillati…
RT @ratika_parkash: Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients with Heart Failure and Atrial Fibrillati…
Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients with Heart Failure and Atrial Fibrillation: Results from the RAFT-AF trial | Circulation https://t.co/LyoChYBCdX
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
RT @ratika_parkash: Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients with Heart Failure and Atrial Fibrillati…
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
RT @Dr_Santangeli: RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction…
RAFT-AF just published. Trial stopped early by DSMB for apparent futility. However, there was a trend towards reduction in mortality (HR 0.71, 95% CI 0.49-1.03), and statistically significant improvement in LVEF, QoL and 6MWT in the ablation arm https://t.co/JO4ghZqwji
Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients with Heart Failure and Atrial Fibrillation: results from the RAFT-AF trial https://t.co/6USscnP9Vi @AnthonyTang6 @EPjeff17 @CHRS_SCR @CANetChat