Sequence-dependent model of genes with dual σ factor preference.

Ines S C Baptista, Vinodh Kandavalli, Vatsala Chauhan, Mohamed N M Bahrudeen, Bilena L B Almeida, Cristina S D Palma, Suchintak Dash, Andre S Ribeiro

April 2022 Biochim Biophys Acta Gene Regul Mech

Synopsis of Social media discussions

Several discussions highlight the role of sigma factors and gene regulation, with phrases like 'describing recent works' and 'role of sigma factors' showcasing enthusiasm and curiosity. The tone is technical yet accessible, emphasizing the research's scientific relevance and potential applications.

A
Agreement
 Moderate agreement

Most discussions acknowledge the significance of the research on sigma factors and gene regulation, reflecting general agreement with its importance.

I
Interest
 High level of interest

Posts show high interest, especially with mentions of videos explaining the work and the relevance to E. coli, which capture audience attention.

E
Engagement
 Moderate level of engagement

Comments reference specific elements like sigma factors and the functions of genes, indicating active engagement with the concepts and methods.

I
Impact
 Moderate level of impact

The discussions suggest that the publication could influence future studies and synthetic gene circuit design, indicating a moderate impact.

Social Mentions

YouTube

1 Videos

Twitter

16 Posts

News

1 Articles

Metrics

Video Views

470

Total Likes

22

Extended Reach

10,299

Social Features

18

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

E. coli Genes with Dual Sigma Factor Preference and Regulatory Dynamics

E. coli Genes with Dual Sigma Factor Preference and Regulatory Dynamics

This study examines the sequence and dynamics of E. coli genes with dual sigma factor preference, highlighting how promoter sequences influence gene responses during different growth phases and stresses, with implications for synthetic gene circuit design.

Laboratory of Biosystem Dynamics

January 10, 2023

470 views

  • Bilena Brito Almeida
    @BilenaLBAlmeida (Twitter)

    RT @AndreSR_Lab: We have published (in our laboratory's YouTube channel) a short video describing one of our recent works on the role of si…
    view full post

    January 10, 2023

    3

  • Ines S. C. Baptista
    @InesSCBaptista (Twitter)

    RT @AndreSR_Lab: We have published (in our laboratory's YouTube channel) a short video describing one of our recent works on the role of si…
    view full post

    January 10, 2023

    3

  • Vatsala Chauhan
    @vatsalachauhan7 (Twitter)

    RT @AndreSR_Lab: We have published (in our laboratory's YouTube channel) a short video describing one of our recent works on the role of si…
    view full post

    January 10, 2023

    3

  • Andre Ribeiro's Lab
    @AndreSR_Lab (Twitter)

    We have published (in our laboratory's YouTube channel) a short video describing one of our recent works on the role of sigma factors in gene expression regulation!
    view full post

    January 10, 2023

    4

    3

  • Huy Tran
    @HuyTran_hn (Twitter)

    RT @AndreSR_Lab: Do you know that some #Ecoli
    view full post

    April 4, 2022

    11

  • Jarno Mäkelä
    @MakelaJarno (Twitter)

    RT @AndreSR_Lab: Do you know that some #Ecoli
    view full post

    April 3, 2022

    11

  • Jonathan Massera
    @jon_massera (Twitter)

    RT @AndreSR_Lab: Do you know that some #Ecoli
    view full post

    April 1, 2022

    11

  • Bioinformatics Trends 
    @BinfoTrends (Twitter)

    RT @AndreSR_Lab: Do you know that some #Ecoli
    view full post

    April 1, 2022

    11

  • Vinodh Kandavalli
    @Vinod2988 (Twitter)

    RT @AndreSR_Lab: Do you know that some #Ecoli
    view full post

    April 1, 2022

    11

  • Mohamed Bahrudeen
    @MohamedBahru (Twitter)

    RT @AndreSR_Lab: Do you know that some #Ecoli
    view full post

    April 1, 2022

    11

  • Cristina Palma
    @CristinaASDP (Twitter)

    RT @AndreSR_Lab: Do you know that some #Ecoli
    view full post

    April 1, 2022

    11

  • Samuel Oliveira
    @samuel_matos_ (Twitter)

    RT @AndreSR_Lab: Do you know that some #Ecoli
    view full post

    April 1, 2022

    11

  • Bilena Brito Almeida
    @BilenaLBAlmeida (Twitter)

    RT @AndreSR_Lab: Do you know that some #Ecoli
    view full post

    April 1, 2022

    11

  • Vatsala Chauhan
    @vatsalachauhan7 (Twitter)

    RT @AndreSR_Lab: Do you know that some #Ecoli
    view full post

    April 1, 2022

    11

  • Ines S. C. Baptista
    @InesSCBaptista (Twitter)

    RT @AndreSR_Lab: Do you know that some #Ecoli
    view full post

    April 1, 2022

    11

  • Andre Ribeiro's Lab
    @AndreSR_Lab (Twitter)

    Do you know that some #Ecoli
    view full post

    April 1, 2022

    14

    11

  • Sigma Factor Relatives in Eukaryotes | Science

    Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 1865, 3, (194812), (2022).https://doi.org/10.1016/j.bbagrm.2022.194812 · Crossref. Vinodh K ...
    view full post

    December 16, 2025

    News

Abstract Synopsis

  • Most genes in E. coli respond to a single regulatory factor, but about 5% have dual factor preferences, especially for factors that control housekeeping functions and stress responses.
  • The study shows that gene activation levels are quite similar during stationary growth and other phases, and there is a quantitative link between the gene's promoter sequence and how strongly it responds to changes in factor levels.
  • They developed and validated a sequence-based model that predicts gene sensitivity during different growth phases and stresses, suggesting that these promoter variants could be used to design synthetic gene circuits with predictable responses.]