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Am J Obstet Gynecol September 2022 PMID 35364061

Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive and systematic review with meta-analysis.

Ana Raquel Neves, Pedro Montoya-Botero, Nikolaos P Polyzos

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Mentions

51
Peak: 36 in Sep 2022
across 4 sources since Mar 2022

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Mar 2022 – Oct 2025

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AI synopsis

What people are saying

Several discussions highlight the detailed review of how androgens influence folliculogenesis and vary by developmental stage, with phrases like 'great job w/ literature review' and indications that some question DHEA's effectiveness. The tone varies from appreciative to mildly skeptical about the clinical implications, showing a nuanced engagement that balances recognition of scientific rigor with questions about practical outcomes.

AgreementNeither agree nor disagree

Most discussions acknowledge the thorough review process, with some uncertainty about specific claims like the efficacy of DHEA, indicating mixed levels of support.

InterestModerate interest

Posts demonstrate moderate curiosity, often referencing elements like the comprehensive nature of the review and variations in androgen effects, suggesting some engagement with the topic.

EngagementModerate engagement

Comments include noting details such as the role of androgens at different follicle stages and referencing meta-analytical findings, implying a modest but focused engagement with the study's scientific content.

ImpactNeutral impact

Overall, discussions recognize the significance of the review but do not suggest it is groundbreaking, reflecting a perception of moderate impact on clinical practice.

Abstract in brief

  • The study reviews the role of androgens in folliculogenesis and evaluates therapeutic approaches for androgen supplementation in patients with diminished ovarian reserve and poor responders in IVF treatments.
  • Data was gathered from various medical databases up until September 2021, focusing on randomized controlled trials that compared androgens like dehydroepiandrosterone and testosterone versus conventional IVF protocols.
  • The meta-analysis found no significant differences in outcomes such as the number of oocytes retrieved, clinical pregnancy rate, or live-birth rate between the androgen and placebo treatments.
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AJOG
@AJOG_thegray · X

Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive and systematic review with meta-analysis: Different androgen effects depending on the follicle developmental stage https://t.co/55aDYs1F3T https://t.co/LFDyGHYMvd

Sep 26, 2022 · 47 likes · 25 shares · 31,764 followers View post →
AJOG
@AJOG_thegray · X

AJOG Presents: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive and systematic review with meta-analysis https://t.co/twFmEFg5W9 https://t.co/P96gBIBG6B

Sep 4, 2022 · 23 likes · 8 shares · 31,764 followers View post →
AJOG
@AJOG_thegray · X

AJOG Presents: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive and systematic review with meta-analysis https://t.co/twFmEFg5W9 https://t.co/7BYZuT0LkR

Sep 18, 2022 · 18 likes · 8 shares · 31,764 followers View post →
AJOG
@AJOG_thegray · X

AJOG Presents: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive and systematic review with meta-analysis https://t.co/1LVlENrYEB https://t.co/c2oDbymtAz

Aug 25, 2022 · 9 likes · 4 shares · 31,764 followers View post →
AJOG
@AJOG_thegray · X

Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive and systematic review with meta-analysis https://t.co/1LVlEN9Pqt https://t.co/oyLHVyspMc

Aug 25, 2022 · 6 likes · 3 shares · 31,764 followers View post →
Max Ezzati, MD
@MaxEzzatiMD · X

Not necessarily agree w/suggestion that DHEA doesn’t work, but apart from that, authors did a great job w/ literature review & basic science behind it @PedroMontoyaMD @PolyzosN Androgens and diminished ovarian reserve: the long road from basic sci... https://t.co/LW2YS8bgRr

Sep 30, 2022 · 5 likes · 1,982 followers View post →

All mentions

Max Ezzati, MD
@MaxEzzatiMD · X

Not necessarily agree w/suggestion that DHEA doesn’t work, but apart from that, authors did a great job w/ literature review & basic science behind it @PedroMontoyaMD @PolyzosN Androgens and diminished ovarian reserve: the long road from basic sci... https://t.co/LW2YS8bgRr

Sep 30, 2022 · 5 likes · 1,982 followers View post →
Andres Ricaurte
@aricaurtegineco · X

RT @AJOG_thegray: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive an…

Sep 29, 2022 · 25 shares · 187 followers View post →
HORAC_Grand_Front_Osaka_Clinic【official】
@HORAC42644785 · X

RT @AJOG_thegray: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive an…

Sep 29, 2022 · 25 shares · 49 followers View post →
Ana Rejón
@TotemOso · X

RT @AJOG_thegray: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive an…

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Margalida Vicens
@MargalidaVicens · X

RT @AJOG_thegray: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive an…

Sep 28, 2022 · 25 shares · 555 followers View post →
Dr. Gpe.NavaLoya
@gpe_dra · X

RT @AJOG_thegray: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive an…

Sep 28, 2022 · 25 shares · 154 followers View post →
☀Nacira Barrios.
@nachibarrios · X

RT @AJOG_thegray: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive an…

Sep 27, 2022 · 25 shares · 455 followers View post →
DIATROS woman’s health
@ClinicaDiatros · X

RT @AJOG_thegray: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive an…

Sep 27, 2022 · 25 shares · 1,301 followers View post →
Ros Alba
@RosAlba59703658 · X

RT @AJOG_thegray: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive an…

Sep 26, 2022 · 25 shares · 2 followers View post →
CAOG
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Babu Karavadra
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GynEstetica
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Patty Irala MD.
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RT @AJOG_thegray: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive an…

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Dr. Arturo Mancera
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DiatrosAcademy
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Victor Rangel
@victorsr2 · X

RT @AJOG_thegray: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive an…

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Dr. Jose Alejandro Mendoza
@DrAlejandroMR · X

RT @AJOG_thegray: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive an…

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Nahla نهلة
@nahlabk · X

RT @AJOG_thegray: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive an…

Sep 26, 2022 · 25 shares · 255 followers View post →
Dr. José Luis Neyro
@doctorneyro · X

RT @AJOG_thegray: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive an…

Sep 26, 2022 · 25 shares · 3,861 followers View post →
Ariel Leonor
@arielstgoleonor · X

RT @AJOG_thegray: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive an…

Sep 26, 2022 · 25 shares · 735 followers View post →
Mauricio Moreno
@msmorenob · X

RT @AJOG_thegray: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive an…

Sep 26, 2022 · 25 shares · 21 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @AJOG_thegray: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive an…

Sep 26, 2022 · 25 shares · 6,703 followers View post →
AJOG
@AJOG_thegray · X

Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive and systematic review with meta-analysis: Different androgen effects depending on the follicle developmental stage https://t.co/55aDYs1F3T https://t.co/LFDyGHYMvd

Sep 26, 2022 · 47 likes · 25 shares · 31,764 followers View post →
Carolyn Alexander
@DrCAlexanderFer · X

RT @AJOG_thegray: AJOG Presents: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A…

Sep 18, 2022 · 8 shares · 1,550 followers View post →
Stephanie McDonnell
@spmReproPhys · X

RT @AJOG_thegray: AJOG Presents: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A…

Sep 18, 2022 · 8 shares · 480 followers View post →
Dr. Helen E. Collins
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Sep 18, 2022 · 8 shares · 2,231 followers View post →
Nasser Baabel
@NasserBZ · X

RT @AJOG_thegray: AJOG Presents: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A…

Sep 18, 2022 · 8 shares · 513 followers View post →
SystematicReviewBot
@EvidenceRobot · X

RT @AJOG_thegray: AJOG Presents: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A…

Sep 18, 2022 · 8 shares · 6,703 followers View post →
AJOG
@AJOG_thegray · X

AJOG Presents: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive and systematic review with meta-analysis https://t.co/twFmEFg5W9 https://t.co/7BYZuT0LkR

Sep 18, 2022 · 18 likes · 8 shares · 31,764 followers View post →
Nikolaos P. Polyzos
@PolyzosN · X

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Sep 6, 2022 · 8 shares · 510 followers View post →
SEF
@Sefertilidad · X

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Gerardo Ohara
@OharaGerardo · X

RT @AJOG_thegray: AJOG Presents: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A…

Sep 5, 2022 · 8 shares · 9 followers View post →
Utpal D.Barma
@BarmaUtpal · X

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Nasser Baabel
@NasserBZ · X

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Abdullah Agabawi
@AbdullahAgabawi · X

RT @AJOG_thegray: AJOG Presents: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A…

Sep 4, 2022 · 8 shares · 705 followers View post →
AJOG
@AJOG_thegray · X

AJOG Presents: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive and systematic review with meta-analysis https://t.co/twFmEFg5W9 https://t.co/P96gBIBG6B

Sep 4, 2022 · 23 likes · 8 shares · 31,764 followers View post →
Rafael SchezBorrego
@SchezBorrego · X

RT @AJOG_thegray: AJOG Presents: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A…

Aug 26, 2022 · 4 shares · 3,348 followers View post →
Abdullah Agabawi
@AbdullahAgabawi · X

RT @AJOG_thegray: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive an…

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Cristiano de Pádua Souza
@DrCrisPadua · X

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PedroMontoyaMD
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RT @AJOG_thegray: AJOG Presents: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A…

Aug 25, 2022 · 4 shares · 259 followers View post →
AJOG
@AJOG_thegray · X

AJOG Presents: Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive and systematic review with meta-analysis https://t.co/1LVlENrYEB https://t.co/c2oDbymtAz

Aug 25, 2022 · 9 likes · 4 shares · 31,764 followers View post →
AJOG
@AJOG_thegray · X

Androgens and diminished ovarian reserve: the long road from basic science to clinical implementation. A comprehensive and systematic review with meta-analysis https://t.co/1LVlEN9Pqt https://t.co/oyLHVyspMc

Aug 25, 2022 · 6 likes · 3 shares · 31,764 followers View post →
INDoximity
@indoximity · X

Androgens and diminished ovarian reserve: The long road from basic science to clinical implementation. A comprehensive and systematic review with meta-analysis https://t.co/StG6QWxtHY

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