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A number of discussions highlight key aspects of the article, such as comparisons between tebipenem and intravenous ertapenem, with phrases like 'non-inferior' signaling approval. Others note the challenges surrounding FDA approval, mentioning concerns about its rejection and potential implications for antibiotic resistance. The varied tone, ranging from excitement about a new treatment option to anxiety over possible misuse, underscores the complex sentiment surrounding this publication.
The overall sentiment shows moderate support for the findings of the publication, with several discussions expressing agreement about its potential efficacy.
There is high interest in the new oral antibiotic, as many users inquire about its clinical applications and express eagerness to see it available.
While many posts reflect moderate engagement, some users delve into the specifics of the research and its implications for antibiotic treatment.
The community perceives the study as important, believing it has significant implications for treating complicated urinary tract infections.
Have you read the paper? Great! Are you yet to read it? No worries We all know it's about more than just UTI treatment. Are you ready for oral carbapenems in your practice? Join #IDJCLUB tonight at 9pm EST to discuss. All are always welcome.
Great to see a new oral option for Rx of ESBL and AmpC producers: Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection | NEJM https://t.co/jRsiaP0yMf
【Journal Club】 Our fellow, @RitaWilsonDib1 presented a recent NEJM article, oral tebipenem study at Journal Club on Monday! Oral tebipenem was non-inferior to ertapenem for UTI. Great presentation, Rita! https://t.co/YeKxa9HBKv
Ya demostró #tebipenem, carbapenemico oral
@dr_bisono Maybe coming soon though? https://t.co/AwrWRSuOTd
Perorální karbapenem (tebipenem). https://t.co/vtGJckQTIE
On the verge of a postantibiotic reality, there is an urgent clinical need for new antibiotics. In this episode of Communicable, Erin McCreary hosts experts to discuss the antimicrobial development pipeline, including…
RT @ABsteward:
@IljaKarl @doc_ecmo @Chr_Schoeps Dauert nicht mehr lange… https://t.co/n4ton7XUVs Aus Indien sogar bestellbar in die EU… https://t.co/fD3Sc4p9Ba
@unadottoressa @LiffersGert @IchBinTotmuede @vmuecke_k @moritz__eckert @Chrissip81 @DrCWerner Gibt’s ja schon…
RT @accpinfdprn: UTIs, ESBLs, oral carbapenems, oh my!
박 정
@kaspants @doc_ecmo Big Pharma is one step ahead... Leider/ erfreulicherweise hat die FDA das Medikament nicht zugelassen... Ein Alptraum für ABS-Ärzte... https://t.co/n4ton7XUVs
RT @infeccHRUmalaga: Ya demostró #tebipenem, carbapenemico oral
RT @infeccHRUmalaga: Ya demostró #tebipenem, carbapenemico oral
RT @infeccHRUmalaga: Ya demostró #tebipenem, carbapenemico oral
Ya demostró #tebipenem, carbapenemico oral
RT @PharmacyJoe: @dr_bisono Maybe coming soon though? https://t.co/AwrWRSuOTd
@dr_bisono Maybe coming soon though? https://t.co/AwrWRSuOTd
RT @arvindcanchi: Oral Tebipenem is equivalent to IV Ertapenem in this study. Would just like to know how Faropenem fares in this regard.…
RT @arvindcanchi: Oral Tebipenem is equivalent to IV Ertapenem in this study. Would just like to know how Faropenem fares in this regard.…
Oral Tebipenem is equivalent to IV Ertapenem in this study. Would just like to know how Faropenem fares in this regard. #nephtwitter https://t.co/jxFr5KkpSL https://t.co/UxSMSZjEMj
RT @davidvanduin: @hboucher3 gives example of tebipenem. NI trial published in @NEJM (https://t.co/5ELSZz3LVv) but FDA did not approve lead…
@hboucher3 gives example of tebipenem. NI trial published in @NEJM (https://t.co/5ELSZz3LVv) but FDA did not approve leading to 75% layoffs at company. #IDWeek2022 https://t.co/s4hobMky5Y
The ADAPT-PO trial compared oral tebipenem with intravenous ertapenem in the treatment of complicated urinary tract infection and acute pyelonephritis. #IDWeek2022 https://t.co/oEMoGpSYax
@P_A_Bradford @safabric We have a somewhat similar product called tebipenem for cUTI: It was non-inferior to IV ertapenem in cUTI and acute pyelonephritis https://t.co/TGSrtmWgfo However, FDA rejected its approval in the US (needs more data) and the company has left the product dev. as a result
@ABsteward Is there a more detailed story on what happened between the April NEJM publication that concluded NI margin was met (https://t.co/FcXAnUVsDc) & now? Still rooting for oral therapies for cUTI!
12/14 A recently published trial indicated non-inferiority of tebipenem (an oral carbapenem with a similar spectrum of activity as ertapenem) to ertapenem for the treatment of complicated urinary tract infections. https://t.co/DM4y2BTShY
RT @medartbasel: Resistente Keime nehmen auch im ambulanten Setting zB bei Harnwegsinfekten immer weiter zu – sind die neuen #Antibiotika d…
Resistente Keime nehmen auch im ambulanten Setting zB bei Harnwegsinfekten immer weiter zu – sind die neuen #Antibiotika die Lösung? #medArt State of the Art Lecture mit Prof. Tschudin-Sutter Lesen Sie hierzu auch @NEJM: https://t.co/aTXQ5Lscgn #medArt22 @UniSpitalBasel https://t.co/kMREZHg9aA
Publication alert
RT @assiriama: ندرة الحلول ضد البكتيريا المقاومة للمضادات تجعل هذا الخبر مهماً للمختصين مضاد حيوي بالفم من مجموعة carbapenem اظهر فعالية…
https://t.co/SglITcW9nP
RT @ABsteward:
RT @gushamilton: So, the new oral carbapenem everyone was interested in set to be rejected by the FDA based on some post hoc analyses. A so…
RT @EUCIC1: Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection | NEJM https://t.co/vOH1dFv3JZ
RT @gushamilton: So, the new oral carbapenem everyone was interested in set to be rejected by the FDA based on some post hoc analyses. A so…
So, the new oral carbapenem everyone was interested in set to be rejected by the FDA based on some post hoc analyses. A sorry tale in drug development. Whatever you feel about pros/cons oral carbapenem, doesn't feel like a good story. https://t.co/rVPMjJXDP0
RT @EUCIC1: Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection | NEJM https://t.co/vOH1dFv3JZ
RT @EUCIC1: Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection | NEJM https://t.co/vOH1dFv3JZ
Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection | NEJM https://t.co/vOH1dFv3JZ
Coming soon from Japan!! Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection | NEJM https://t.co/anKmT8BRDn
CARBAPENEMICO VIA ORAL? Resistência bacteriana aos antimicrobianos é um grave problema. Internações hospitalares por ausência de um antibiótico oral eficaz não são raras. Esse estudo publicado no NEJM trouxe esperança para esse cenário https://t.co/CbGDQnAoGU
RT @dr_alejandromg: Un nuevo antibiótico oral: Tebipenem Pivoxil 300 miligramos cada 8 horas por 7 días fue: -No inferior que ertapenem par…
Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection https://t.co/lPYEwouIvg
RT @ut_infectious: 【Journal Club】 Our fellow, @RitaWilsonDib1 presented a recent NEJM article, oral tebipenem study at Journal Club on Mond…
RT @ut_infectious: 【Journal Club】 Our fellow, @RitaWilsonDib1 presented a recent NEJM article, oral tebipenem study at Journal Club on Mond…
【Journal Club】 Our fellow, @RitaWilsonDib1 presented a recent NEJM article, oral tebipenem study at Journal Club on Monday! Oral tebipenem was non-inferior to ertapenem for UTI. Great presentation, Rita! https://t.co/YeKxa9HBKv
#ECCMID2022 Year in Infectious Diseases Are we ready for a novel oral carbapenem for the treatment of complicated UTIs and acute pyelonephritis?
https://t.co/lQjWSicUZ4
RT @ABsteward:
RT @Yalsowaida: دراسة جديد RCT لأول مضاد حيوي من عائلة
RT @IDJClub: Have you read the paper? Great! Are you yet to read it? No worries We all know it's about more than just UTI treatment. Are y…
RT @IDJClub: Are excited about oral carbapenems? Are you terrified by their broader implications? Join us on the next #IDJClub to discuss t…
RT @IDJClub: Are excited about oral carbapenems? Are you terrified by their broader implications? Join us on the next #IDJClub to discuss t…
Tebipenem, an oral carbapenem, was noninferior to intravenous ertapenem in the treatment of complicated urinary tract infection and acute #pyelonephritis and had a similar safety profile. #antibiotics #UTI @NEJM https://t.co/Qha2bHnI3A
RT @MHcsba: Tebipenem (primer carbapenémico oral) en ITU complicada PD: Buena o mala decisión? DOI: 10.1056/NEJMoa2105462 https://t.co/qiLt…
RT @IDJClub: Are excited about oral carbapenems? Are you terrified by their broader implications? Join us on the next #IDJClub to discuss t…
RT @IDJClub: Have you read the paper? Great! Are you yet to read it? No worries We all know it's about more than just UTI treatment. Are y…
RT @IDJClub: Have you read the paper? Great! Are you yet to read it? No worries We all know it's about more than just UTI treatment. Are y…
RT @IDJClub: Have you read the paper? Great! Are you yet to read it? No worries We all know it's about more than just UTI treatment. Are y…
RT @IDJClub: Have you read the paper? Great! Are you yet to read it? No worries We all know it's about more than just UTI treatment. Are y…
RT @davidantibiotic: Great to see a new oral option for Rx of ESBL and AmpC producers: Oral Tebipenem Pivoxil Hydrobromide in Complicated U…
RT @IDJClub: Have you read the paper? Great! Are you yet to read it? No worries We all know it's about more than just UTI treatment. Are y…
Have you read the paper? Great! Are you yet to read it? No worries We all know it's about more than just UTI treatment. Are you ready for oral carbapenems in your practice? Join #IDJCLUB tonight at 9pm EST to discuss. All are always welcome.
Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection | NEJM https://t.co/VquopbJWSC
経口テビペネム - CCR 50mL/min以下では投与量調節が必要 先日発表されたNEJMの論文と同じグループの著者https://t.co/DREUHdrLA0 戦略的に研究してるなーって思いました！ https://t.co/ZUFlSaRnHK
El tebipenem oral fue no inferior al ertapenem intravenoso en el tratamiento de las ITU complicadas y la pielonefritis aguda: https://t.co/8qWyG707Py vía @NEJM
Perorální karbapenem (tebipenem). https://t.co/vtGJckQTIE
Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection https://t.co/YBXrMrOrqY
An oral carbapenem! https://t.co/eViUfzqct4
RT @IDJClub: Are excited about oral carbapenems? Are you terrified by their broader implications? Join us on the next #IDJClub to discuss t…
RT @ABsteward:
(NEJM) Tebipenem pivoxil oral resultó no inferior a ertapenem IV en el tratamiento de ITU complicada, con un perfil de seguridad similar: ADAPT-PO (EC fase III) https://t.co/alRVFbFxb6
RT @ABsteward:
RT @MHcsba: Tebipenem (primer carbapenémico oral) en ITU complicada PD: Buena o mala decisión? DOI: 10.1056/NEJMoa2105462 https://t.co/qiLt…
RT @accpinfdprn: UTIs, ESBLs, oral carbapenems, oh my!
Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection https://t.co/q5HRsWbCIs
RT @ABsteward:
RT @ABsteward:
RT @ABsteward:
RT @IDJClub: Are excited about oral carbapenems? Are you terrified by their broader implications? Join us on the next #IDJClub to discuss t…
RT @micromunidad: Aunque el ensayo sea en ITUs complicadas, todos somos capaces de ver la borrasca... https://t.co/WRmZhWuSw3
RT @ABsteward:
RT @MHcsba: Tebipenem (primer carbapenémico oral) en ITU complicada PD: Buena o mala decisión? DOI: 10.1056/NEJMoa2105462 https://t.co/qiLt…
RT @Yalsowaida: دراسة جديد RCT لأول مضاد حيوي من عائلة
RT @MHcsba: Tebipenem (primer carbapenémico oral) en ITU complicada PD: Buena o mala decisión? DOI: 10.1056/NEJMoa2105462 https://t.co/qiLt…
Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection | NEJM https://t.co/KqHD9YW0hm
RT @MHcsba: Tebipenem (primer carbapenémico oral) en ITU complicada PD: Buena o mala decisión? DOI: 10.1056/NEJMoa2105462 https://t.co/qiLt…
RT @MHcsba: Tebipenem (primer carbapenémico oral) en ITU complicada PD: Buena o mala decisión? DOI: 10.1056/NEJMoa2105462 https://t.co/qiLt…
RT @the_paper_link: Trend new: Eckburg PB, ..., Talley AK (N Engl J Med) __Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Trac…
RT @MHcsba: Tebipenem (primer carbapenémico oral) en ITU complicada PD: Buena o mala decisión? DOI: 10.1056/NEJMoa2105462 https://t.co/qiLt…
RT @MHcsba: Tebipenem (primer carbapenémico oral) en ITU complicada PD: Buena o mala decisión? DOI: 10.1056/NEJMoa2105462 https://t.co/qiLt…
RT @MHcsba: Tebipenem (primer carbapenémico oral) en ITU complicada PD: Buena o mala decisión? DOI: 10.1056/NEJMoa2105462 https://t.co/qiLt…
RT @MHcsba: Tebipenem (primer carbapenémico oral) en ITU complicada PD: Buena o mala decisión? DOI: 10.1056/NEJMoa2105462 https://t.co/qiLt…
RT @MHcsba: Tebipenem (primer carbapenémico oral) en ITU complicada PD: Buena o mala decisión? DOI: 10.1056/NEJMoa2105462 https://t.co/qiLt…
Trend new: Eckburg PB, ..., Talley AK (N Engl J Med) __Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection__ https://t.co/gA499aQyVr
RT @MHcsba: Tebipenem (primer carbapenémico oral) en ITU complicada PD: Buena o mala decisión? DOI: 10.1056/NEJMoa2105462 https://t.co/qiLt…
RT @MHcsba: Tebipenem (primer carbapenémico oral) en ITU complicada PD: Buena o mala decisión? DOI: 10.1056/NEJMoa2105462 https://t.co/qiLt…
RT @MHcsba: Tebipenem (primer carbapenémico oral) en ITU complicada PD: Buena o mala decisión? DOI: 10.1056/NEJMoa2105462 https://t.co/qiLt…
RT @MHcsba: Tebipenem (primer carbapenémico oral) en ITU complicada PD: Buena o mala decisión? DOI: 10.1056/NEJMoa2105462 https://t.co/qiLt…
RT @MHcsba: Tebipenem (primer carbapenémico oral) en ITU complicada PD: Buena o mala decisión? DOI: 10.1056/NEJMoa2105462 https://t.co/qiLt…
RT @MHcsba: Tebipenem (primer carbapenémico oral) en ITU complicada PD: Buena o mala decisión? DOI: 10.1056/NEJMoa2105462 https://t.co/qiLt…
RT @MHcsba: Tebipenem (primer carbapenémico oral) en ITU complicada PD: Buena o mala decisión? DOI: 10.1056/NEJMoa2105462 https://t.co/qiLt…
On the one hand I am quite excited to see Tebipenem as an oral carbapenem choice, but I also am worried about potential misuse https://t.co/KhkQMrDr06 #medicine #healthcare #residency #USMLE #medschool #doctor
RT @MHcsba: Tebipenem (primer carbapenémico oral) en ITU complicada PD: Buena o mala decisión? DOI: 10.1056/NEJMoa2105462 https://t.co/qiLt…
RT @MHcsba: Tebipenem (primer carbapenémico oral) en ITU complicada PD: Buena o mala decisión? DOI: 10.1056/NEJMoa2105462 https://t.co/qiLt…
RT @MHcsba: Tebipenem (primer carbapenémico oral) en ITU complicada PD: Buena o mala decisión? DOI: 10.1056/NEJMoa2105462 https://t.co/qiLt…
This is a disaster. Small benefit for 1%. Huge risks for the planet. Will do to carbapenems what cefixime has done to 3GCs in countries where more than half the world live. Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection | NEJM https://t.co/uvRoIrAuHM
Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection | NEJM https://t.co/b5I2m4KMXz
Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection | NEJM https://t.co/ISmWgYnzDC
Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection https://t.co/D4PKuiEX91
Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection | NEJM https://t.co/73jlhsMEhh
RT @davidantibiotic: Great to see a new oral option for Rx of ESBL and AmpC producers: Oral Tebipenem Pivoxil Hydrobromide in Complicated U…
RT @LauraPiddock: Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection https://t.co/ypjnU4V7CZ
RT @LuisZuritaG: Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection | NEJM https://t.co/2GarzbeNhj
Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection https://t.co/05UYd5vbv3 https://t.co/vOMxjeXgie
Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection https://t.co/ypjnU4V7CZ
Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection | NEJM https://t.co/2GarzbeNhj
Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection | NEJM https://t.co/nSK4m4bCvw
I wonder how much this is going to cost!! Looks promising. Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection. https://t.co/zgVvd7lszi
Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection | NEJM https://t.co/7OjcVkeFu2
RT @proacyl: Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection ✅ Nueva terapia que reduciría hospitalización ‼️To…
RT @davidantibiotic: Great to see a new oral option for Rx of ESBL and AmpC producers: Oral Tebipenem Pivoxil Hydrobromide in Complicated U…
RT @proacyl: Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection ✅ Nueva terapia que reduciría hospitalización ‼️To…
RT @proacyl: Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection ✅ Nueva terapia que reduciría hospitalización ‼️To…
Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection ✅ Nueva terapia que reduciría hospitalización ‼️Todos serán bienvenidos, siempre que se prescriban bajo supervisión #PROA ‼️ https://t.co/imjkivjvkO
Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection https://t.co/am6uqGITdG
RT @davidantibiotic: Great to see a new oral option for Rx of ESBL and AmpC producers: Oral Tebipenem Pivoxil Hydrobromide in Complicated U…
Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection | NEJM https://t.co/U5aPK0gaH0
Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection @NEJM https://t.co/B1nyxu2YCf #infection #clinicaltrials #research @TheInnovation_M @The_InnovationJ
RT @davidantibiotic: Great to see a new oral option for Rx of ESBL and AmpC producers: Oral Tebipenem Pivoxil Hydrobromide in Complicated U…
Great to see a new oral option for Rx of ESBL and AmpC producers: Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection | NEJM https://t.co/jRsiaP0yMf
Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection | NEJM https://t.co/iU9E3T0UwH
Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection | NEJM https://t.co/Y6N4WhhYTn Nice but still no oral agents against DTR Pseudomonas
Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection | NEJM https://t.co/Zju5cKSEXJ