April 2022 PMID 35463332

SIRT6 Widely Regulates Aging, Immunity, and Cancer.

Yunjia Li, Jing Jin, Yi Wang

Mentions

7
Peak: 2 in Jun 2025
across 2 sources since Apr 2022

Extended reach

18,170
potential audience

Total likes

90

Video views

2,691

Mentions per month

Apr 2022 – Jun 2025

Where it's discussed

  • X / Twitter5 posts
  • YouTube2 videos

AI synopsis

What people are saying

The groups of discussions highlight the significance of SIRT6's biochemical functions and its potential for developing therapies, with phrases like 'potential therapeutic target' and explanations of its roles in aging and immunity indicating high engagement and impact, driven by technical language and focus on medical advances.

AgreementModerate agreement

Most discussions recognize the importance of SIRT6 in regulating aging, immunity, and cancer, indicating broad agreement with the publication's findings.

InterestHigh interest

The posts express high curiosity about the biological mechanisms and therapeutic potential, highlighting strong interest.

EngagementModerate engagement

Posts delve into details such as SIRT6's biochemical activities and potential as a treatment target, showing active engagement.

ImpactHigh impact

The discussions emphasize the profound implications for disease treatment and aging research, demonstrating high perceived impact.

Abstract in brief

  • SIRT6 is a protein in mammals that has multiple biochemical activities, including deacetylation, defattyacylation, and monoADPribosylation, which are important for its regulatory roles in various physiological and pathological processes.
  • The review highlights the significant role of SIRT6 in aging, cancer, and especially immune system regulation, focusing on how it affects immune cell function through mechanisms like immunesenescence, immunometabolism, and tumor immunology.
  • Due to its influence on immune system regulation, SIRT6 is viewed as a promising target for developing treatments for age-related diseases, cancer, and immune-related conditions.]

Top posts

Most liked on X and Bluesky
老化を遅らせることに成功しているかも
@roukaokurasu · X

SIRT6と老化 "SIRT6は、細胞、組織、臓器、そして身体に抗老化作用を持つ重要なタンパク質です。DNA損傷修復の促進、染色体の正常なテロメア構造の維持、グルコースとNAD +の代謝バランスの調節、そしてSASPの調節という4つの主要な経路を介して老化を抑制します。" https://t.co/OcDO1oncQK

Jun 27, 2025 · 3 likes · 2,581 followers View post →
Orlando_uy
@Orlando_uy · X

SIRT6 Widely Regulates Aging, Immunity, and Cancer. SIRT6 can be considered to be a potential therapeutic target for the treatment of diseases. https://t.co/EEzcFd1IeZ

May 10, 2022 · 3 likes · 698 followers View post →
老化を遅らせることに成功しているかも
@roukaokurasu · X

老化におけるSIRT6の生理学と病理学 "SIRT6は老化を遅らせ、テロメアとゲノムの安定性維持に関与する長寿タンパク質である。" https://t.co/OcDO1omF1c

May 29, 2025 · 1 like · 2,581 followers View post →
Frontiers - Oncology
@FrontOncology · X

New research: SIRT6 Widely Regulates Aging, Immunity, and Cancer: SIRT6 is a member of the Sir2-like family in mammals. Recent structural and biochemical studies have characterized SIRT6 as having deacetylation, defatty-acylation, and… https://t.co/IlIU2gMzwI #oncology

Apr 6, 2022 · 6,509 followers View post →

All mentions

老化を遅らせることに成功しているかも
@roukaokurasu · X

SIRT6と老化 "SIRT6は、細胞、組織、臓器、そして身体に抗老化作用を持つ重要なタンパク質です。DNA損傷修復の促進、染色体の正常なテロメア構造の維持、グルコースとNAD +の代謝バランスの調節、そしてSASPの調節という4つの主要な経路を介して老化を抑制します。" https://t.co/OcDO1oncQK

Jun 27, 2025 · 3 likes · 2,581 followers View post →
luis hernan graffe
@hernangraffe · X

https://t.co/pSevGt4c3i

Jun 26, 2025 · 3,111 followers View post →
老化を遅らせることに成功しているかも
@roukaokurasu · X

老化におけるSIRT6の生理学と病理学 "SIRT6は老化を遅らせ、テロメアとゲノムの安定性維持に関与する長寿タンパク質である。" https://t.co/OcDO1omF1c

May 29, 2025 · 1 like · 2,581 followers View post →
Orlando_uy
@Orlando_uy · X

SIRT6 Widely Regulates Aging, Immunity, and Cancer. SIRT6 can be considered to be a potential therapeutic target for the treatment of diseases. https://t.co/EEzcFd1IeZ

May 10, 2022 · 3 likes · 698 followers View post →
Frontiers - Oncology
@FrontOncology · X

New research: SIRT6 Widely Regulates Aging, Immunity, and Cancer: SIRT6 is a member of the Sir2-like family in mammals. Recent structural and biochemical studies have characterized SIRT6 as having deacetylation, defatty-acylation, and… https://t.co/IlIU2gMzwI #oncology

Apr 6, 2022 · 6,509 followers View post →