April 2022 PMID 35492709

Clinical and Genetic Correlates of Bipolar Disorder With Childhood-Onset Attention Deficit Disorder.

Nicolas A Nunez, Brandon J Coombes, Francisco Romo-Nava, David J Bond, Jennifer Vande Voort, Paul E Croarkin, Nicole Leibman, Manuel Gardea Resendez, Marin Veldic, Hannah Betcher, Balwinder Singh, Colin Colby, Alfredo Cuellar-Barboza, Miguel Prieto, Katherine M Moore

Mentions

7
Peak: 3 in Dec 2024
across 2 sources since Apr 2022

Extended reach

52,587
potential audience

Total likes

1,121

Video views

33,668

Mentions per month

Apr 2022 – Dec 2024

Where it's discussed

  • X / Twitter4 posts
  • YouTube3 videos

AI synopsis

What people are saying

Overall, the discussions indicate a balanced interest in the study's insights, with some posts emphasizing the clinical importance of the findings, such as elevated genetic risks and treatment responses, and using phrases like 'important implications' and 'complex clinical features' to underscore the impact.

AgreementModerate agreement

Most discussions acknowledge the findings linking childhood-onset ADHD with bipolar disorder and its genetic and clinical implications.

InterestModerate interest

Participants show moderate curiosity about the genetic aspects and clinical features described in the study.

EngagementModerate engagement

Comments include references to specific genetic scores and treatment responses, indicating some depth in engagement.

ImpactModerate impact

The discussions highlight the significance of understanding comorbidities and genetics for treatment, suggesting perceived substantial impact.

Abstract in brief

  • The study found that bipolar disorder (BD) patients with childhood-onset ADHD tend to be younger, predominantly male, and have more co-occurring conditions like anxiety and substance use disorders, along with poorer responses to certain mood stabilizers.
  • Genetically, all BD groups showed higher risk scores for BD and ADHD compared to controls, but only those with childhood-onset ADHD (BDcADHD) had significantly higher ADHD polygenic risk scores than BD patients without ADHD, suggesting a stronger genetic influence on early ADHD symptoms.
  • Overall, BD with childhood-onset ADHD is linked to more complex clinical features and a greater genetic contribution, which may impact treatment responses and disease management.]

Top posts

Most liked on X and Bluesky
Frontiers - Psychiatry
@FrontPsychiatry · X

New Research: Clinical and Genetic Correlates of Bipolar Disorder With Childhood-Onset Attention Deficit Disorder: Background: Bipolar disorder (BD) with co-occurring attention deficit-hyperactivity disorder (ADHD) is associated with an… https://t.co/5ZmWSJS7p8 #Psychiatry

Apr 14, 2022 · 1 like · 1 share · 16,496 followers View post →
iBraiN Inserm Lab
@iBrain_Inserm · X

RT @FrontPsychiatry: New Research: Clinical and Genetic Correlates of Bipolar Disorder With Childhood-Onset Attention Deficit Disorder: Bac…

Apr 14, 2022 · 1 share · 1,723 followers View post →
PRS papers
@PRS_pubmed · X

Clinical and Genetic Correlates of Bipolar Disorder With Childhood-Onset Attention Deficit Disorder https://t.co/Ce8MLASlZu

May 2, 2022 · 400 followers View post →
Bryan Rojas-Huerta
@Bryanrhx03 · X

BD+cADHD was associated with a greater number of comorbidities and reduced response to mood stabilizing treatments. The higher ADHD PRS for the BD+cADHD group may reflect a greater influence of genetic factors on early presentation of ADHD symptoms. DOI: 10.3389/fpsyt.2022.884217

Mar 5, 2024 · 297 followers View post →

All mentions

Bryan Rojas-Huerta
@Bryanrhx03 · X

BD+cADHD was associated with a greater number of comorbidities and reduced response to mood stabilizing treatments. The higher ADHD PRS for the BD+cADHD group may reflect a greater influence of genetic factors on early presentation of ADHD symptoms. DOI: 10.3389/fpsyt.2022.884217

Mar 5, 2024 · 297 followers View post →
PRS papers
@PRS_pubmed · X

Clinical and Genetic Correlates of Bipolar Disorder With Childhood-Onset Attention Deficit Disorder https://t.co/Ce8MLASlZu

May 2, 2022 · 400 followers View post →
iBraiN Inserm Lab
@iBrain_Inserm · X

RT @FrontPsychiatry: New Research: Clinical and Genetic Correlates of Bipolar Disorder With Childhood-Onset Attention Deficit Disorder: Bac…

Apr 14, 2022 · 1 share · 1,723 followers View post →
Frontiers - Psychiatry
@FrontPsychiatry · X

New Research: Clinical and Genetic Correlates of Bipolar Disorder With Childhood-Onset Attention Deficit Disorder: Background: Bipolar disorder (BD) with co-occurring attention deficit-hyperactivity disorder (ADHD) is associated with an… https://t.co/5ZmWSJS7p8 #Psychiatry

Apr 14, 2022 · 1 like · 1 share · 16,496 followers View post →