PD-1 Blockade in Mismatch Repair-Deficient, Locally Advanced Rectal Cancer.

Andrea Cercek, Melissa Lumish, Jenna Sinopoli, Jill Weiss, Jinru Shia, Michelle Lamendola-Essel, Imane H El Dika, Neil Segal, Marina Shcherba, Ryan Sugarman, Zsofia Stadler, Rona Yaeger, J Joshua Smith, Benoit Rousseau, Guillem Argiles

June 2022

Synopsis of Social media discussions

The collective sentiment is overwhelmingly positive, highlighting the extraordinary outcome where 12 out of 12 patients with advanced rectal cancer achieved complete remission without surgery or chemo. Words like 'game-changing,' 'incredible efficacy,' and 'paradigm shift' demonstrate excitement and recognition of potential medical breakthroughs, driven by the clear reporting of 100% success among study participants.

A
Agreement
 Strong agreement

Most discussions celebrate the study's remarkable results, emphasizing that all patients experienced complete remission, indicating strong consensus.

I
Interest
 High level of interest

The persistent attention and detailed commentary reflect a high level of curiosity and engagement from the community.

E
Engagement
 High engagement

Many comments analyze the significance, potential for changing treatment norms, and implications for future cancer therapy, showing deep involvement.

I
Impact
 High level of impact

Several discussions label this as a paradigm-shifting breakthrough with potentially transformative effects on cancer treatment practices.

Social Mentions

YouTube

6 Videos

Bluesky

2 Posts

Facebook

15 Posts

Twitter

369 Posts

Blogs

29 Articles

News

800 Articles

Reddit

8 Posts

Metrics

Video Views

270,164

Total Likes

11,996

Extended Reach

2,922,845

Social Features

1,229

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

PD-1 Blockade Shows Promising Results in Mismatch Repair-Deficient Rectal Cancer

PD-1 Blockade Shows Promising Results in Mismatch Repair-Deficient Rectal Cancer

Neoadjuvant chemotherapy and radiation are standard treatments for locally advanced rectal cancer, particularly in cases with mismatch repair deficiency, which may respond well to PD-1 blockade therapy. A phase 2 study used dostarlimab, an anti-PD-1 antibody, leading to complete responses in all patients without severe side

doctorpetrik

January 17, 2024

148,164 views

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New Hope in Cancer Treatment with Dostarlimab for Rectal Cancer

New Hope in Cancer Treatment with Dostarlimab for Rectal Cancer

Article httpswwwnejmorgdoifull101056NEJMoa2201445. A phase 2 study using dostarlimab, an anti-PD-1 antibody, shows complete tumor response in mismatch repair-deficient rectal cancer patients, potentially allowing some to avoid chemoradiotherapy and surgery.

Dr. Alberto E. Cuello Bioquimica

April 9, 2024

1,482 views

PD-1 Blockade Shows Promise in Advanced Mismatch Repair-Deficient Rectal Cancer

PD-1 Blockade Shows Promise in Advanced Mismatch Repair-Deficient Rectal Cancer

Locally advanced rectal cancer often involves chemotherapy, radiotherapy, and surgery. In a recent study, PD-1 inhibitor dostarlimab was used for 6 months in mismatch repair deficient tumors, leading to complete responses in all 12 patients without additional treatments.

NEJM Group

March 28, 2024

245 views

PD-1 Blockade Shows Promise in Treating Mismatch Repair-Deficient Rectal Cancer

PD-1 Blockade Shows Promise in Treating Mismatch Repair-Deficient Rectal Cancer

The video discusses a clinical trial where dostarlimab, an anti-PD-1 therapy, was used to treat 12 patients with mismatch repair-deficient rectal cancer, resulting in complete tumor disappearance and no significant adverse effects.

InformaVideos

June 9, 2022

39 views

Promising Results of PD-1 Blockade in Mismatch Repair-Deficient Rectal Cancer

Promising Results of PD-1 Blockade in Mismatch Repair-Deficient Rectal Cancer

This video discusses a phase 2 study evaluating dostarlimab, an anti-PD-1 therapy, showing a complete tumor response in all patients with mismatch repair-deficient rectal cancer, potentially reducing the need for chemoradiotherapy and surgery.

Areyouhealthy

June 8, 2022

11 views

  • Emily
    @Emily_Li8 (Twitter)

    RT @ShiningScience: Peer-reviewed Reference: Cercek A, et al. “PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer.…
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    November 19, 2025

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  • SILICONE
    @lpolq2_Yplq2l (Twitter)

    RT @ShiningScience: Peer-reviewed Reference: Cercek A, et al. “PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer.…
    view full post

    November 19, 2025

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  • @Eiernockerln (Twitter)

    RT @ShiningScience: Peer-reviewed Reference: Cercek A, et al. “PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer.…
    view full post

    November 19, 2025

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  • Deepak Sainju, Ph. D.
    @SainjuDeepak (Twitter)

    RT @ShiningScience: Peer-reviewed Reference: Cercek A, et al. “PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer.…
    view full post

    November 19, 2025

    5

  • Shining Science
    @ShiningScience (Twitter)

    Peer-reviewed Reference: Cercek A, et al. “PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer.” New England Journal of Medicine.
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    November 19, 2025

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  • Abdullah Mahmod
    @AbdullahMa90177 (Twitter)

    @edivdealed Cercek, A., Lumish, M., Sinopoli, J., Weiss, J., Yaeger, R., Cercek, A., … Diaz, L. A. Jr. (2022). PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer. The New England Journal of Medicine (NEJM), 386(25), 2363–2376. https://t.co/2F5M8RL4Ut
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    October 24, 2025

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  • gerfaud
    @Gerfaud07 (Twitter)

    @denisrancourt At the turn of the 1980s, Michel Foucault coined an expression that enjoyed dazzling success : the notion of "biopower." also immunotherapy might be useful DOI: 10.1056/NEJMoa2201445
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    August 5, 2025

  • OncoStation: Cancer Facts & Research
    @oncostation (Twitter)

    Fact #84: A small clinical trial used an immunotherapy drug that led to a 100% remission rate in rectal cancer patients. 12 patients were treated and after 6 months cancer was undetectable in each one. https://t.co/WYKEpxy9ST
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    May 30, 2025

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  • JoesBean
    @joesbean (Twitter)

    @VigilantFox https://t.co/bqkQNgLxrs
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    May 25, 2025

  • Marian Keylock
    @KeylockM (Twitter)

    RT @AndreaCercek: Very proud of our study published in @NEJM. 100% clinical complete response with dostarlimab alone in mismatch repair-def…
    view full post

    May 13, 2025

    1091

  • Speedy
    @philosospeedy (Twitter)

    RT @AndreaCercek: Very proud of our study published in @NEJM. 100% clinical complete response with dostarlimab alone in mismatch repair-def…
    view full post

    May 13, 2025

    1091

  • Marcel
    @Marcel20121994 (Twitter)

    @DefiantLs https://t.co/jQg3zmdGF4
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    May 13, 2025

  • BadgerPatriotDC
    @BadgerPatriotDC (Twitter)

    RT @AndreaCercek: Very proud of our study published in @NEJM. 100% clinical complete response with dostarlimab alone in mismatch repair-def…
    view full post

    April 12, 2025

    1091

  • Rosemary J
    @rosemary_j53210 (Twitter)

    @SPOTNEWSonIG Have you seen this Spot? Just checking. Just came out. https://t.co/pwu5CgVkUy
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    April 11, 2025

  • Ferdinanda
    @FerdinandaGiac1 (Twitter)

    RT @Robertonuzzoam: NEW ENGLAND JOURNAL MEDICINE (PDF in italiano): https://t.co/6VTK0AlKpS NEW ENGLAND JOURNAL MEDICINE 2022 (originale):…
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    April 10, 2025

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  • Annalisa B.
    @annalisa776 (Twitter)

    Notizia ORIGINALE (2022):* https://t.co/XEXKKBZjYR *Studio scientifico in italiano (pdf):* https://t.co/tfh2IRLO6f *Studio scientifico originale:* https://t.co/7ielz6OQFy
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    April 10, 2025

  • عبدالله ابوفارس
    @9Rrxrr (Twitter)

    RT @NedaaAlkhamis: دراسة طبية أوردت نتائج مذهلة لعلاج سرطان المستقيم باستخدام الأجسام المضادة وحيدة النسيلة (Monoclonal Antibodies)، سابقة…
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    April 10, 2025

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  • Fe
    @FedericaMarzan (Twitter)

    RT @Robertonuzzoam: NEW ENGLAND JOURNAL MEDICINE (PDF in italiano): https://t.co/6VTK0AlKpS NEW ENGLAND JOURNAL MEDICINE 2022 (originale):…
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    April 10, 2025

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  • Ricky Shields
    @ParkerRick64 (Twitter)

    RT @drCParks1: The original paper. https://t.co/ftnr06q489
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    April 9, 2025

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  • Galactic Shield Maiden
    @GalacticShield (Twitter)

    RT @Humanspective: SOURCE research paper (1) https://t.co/SAKXP1oiY0 https://t.co/oBq3VJXASB
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    April 9, 2025

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  • Galactic Shield Maiden
    @GalacticShield (Twitter)

    RT @Humanspective: SOURCE (1) Andrea Cerceck Regarding clinical trial research paper - "PD-1 Blockade in Mismatch Repair–Deficient, Locally…
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    April 9, 2025

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  • leone5464
    @leone52641 (Twitter)

    RT @Robertonuzzoam: NEW ENGLAND JOURNAL MEDICINE (PDF in italiano): https://t.co/6VTK0AlKpS NEW ENGLAND JOURNAL MEDICINE 2022 (originale):…
    view full post

    April 9, 2025

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  • Antonio Greco
    @steve_241_bis (Twitter)

    RT @Robertonuzzoam: NEW ENGLAND JOURNAL MEDICINE (PDF in italiano): https://t.co/6VTK0AlKpS NEW ENGLAND JOURNAL MEDICINE 2022 (originale):…
    view full post

    April 9, 2025

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  • Roberto Nuzzo
    @Robertonuzzoam (Twitter)

    NEW ENGLAND JOURNAL MEDICINE (PDF in italiano): https://t.co/6VTK0AlKpS NEW ENGLAND JOURNAL MEDICINE 2022 (originale): https://t.co/pE0uuMMEHN SCIENCE DIRECT 2024 (pdf in italiano): https://t.co/St8NXPjfig SCIENCE DIRECT (originale): https://t.co/lWOX0TW2Pz https://t.co/LGLp7oAe7c
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    April 9, 2025

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  • Christina Parks
    @drCParks1 (Twitter)

    The original paper. https://t.co/ftnr06q489
    view full post

    April 9, 2025

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    1

  • Veronique B
    @cleopatra77210 (Twitter)

    Studie: https://t.co/VUhGe6jZOX
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    April 8, 2025

  • dennisgagnon
    @ReDG88775871 (Twitter)

    Study: https://t.co/krUINxLvJX https://t.co/uyum4NBX4u
    view full post

    April 8, 2025

  • جـ❤ـمـ❤ـآلَ آنـ❤ـشـ❤ـيـ❤ـد
    @elhelladj (Twitter)

    RT @NedaaAlkhamis: دراسة طبية أوردت نتائج مذهلة لعلاج سرطان المستقيم باستخدام الأجسام المضادة وحيدة النسيلة (Monoclonal Antibodies)، سابقة…
    view full post

    April 8, 2025

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  • TJ..Troy 4 short :)
    @kuhnu2012 (Twitter)

    RT @Humanspective: SOURCE (1) Andrea Cerceck Regarding clinical trial research paper - "PD-1 Blockade in Mismatch Repair–Deficient, Locally…
    view full post

    April 8, 2025

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  • إبراهيـم البنـاوي☀
    @Albnawi8 (Twitter)

    RT @NedaaAlkhamis: دراسة طبية أوردت نتائج مذهلة لعلاج سرطان المستقيم باستخدام الأجسام المضادة وحيدة النسيلة (Monoclonal Antibodies)، سابقة…
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    April 8, 2025

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  • Johannes ✞
    @Johannes101021 (Twitter)

    @MichaiMorin @TheProjectUnity Until then you can read the origin study here: https://t.co/uLSvA6vgkb (I dont get how one can skip that simple research to provide the paper in his post about it, but I know this is how social media works
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    April 8, 2025

  • oddDuck
    @oddDuck54 (Twitter)

    RT @Humanspective: SOURCE research paper (1) https://t.co/SAKXP1oiY0 https://t.co/oBq3VJXASB
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    April 8, 2025

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  • oddDuck
    @oddDuck54 (Twitter)

    RT @Humanspective: SOURCE (1) Andrea Cerceck Regarding clinical trial research paper - "PD-1 Blockade in Mismatch Repair–Deficient, Locally…
    view full post

    April 8, 2025

    16

  • Aris Gkikas
    @aris_gkikas (Twitter)

    RT @AndreaCercek: Very proud of our study published in @NEJM. 100% clinical complete response with dostarlimab alone in mismatch repair-def…
    view full post

    April 8, 2025

    1091

  • hanan
    @hanana269890 (Twitter)

    RT @NedaaAlkhamis: دراسة طبية أوردت نتائج مذهلة لعلاج سرطان المستقيم باستخدام الأجسام المضادة وحيدة النسيلة (Monoclonal Antibodies)، سابقة…
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    April 8, 2025

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  • LunaBucky
    @Paulina57256038 (Twitter)

    RT @Humanspective: SOURCE research paper (1) https://t.co/SAKXP1oiY0 https://t.co/oBq3VJXASB
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    April 8, 2025

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  • LunaBucky
    @Paulina57256038 (Twitter)

    RT @Humanspective: SOURCE (1) Andrea Cerceck Regarding clinical trial research paper - "PD-1 Blockade in Mismatch Repair–Deficient, Locally…
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    April 8, 2025

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  • BrainbellJangler
    @WaitingForPerot (Twitter)

    Important to note that this all happened before RFK Jr was at the helm of HHS. The original study was published in June 2022: https://t.co/7XLKNYPWVj And yes, there was government funding involved.
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    April 8, 2025

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  • B Strick
    @JustBeGood11 (Twitter)

    RT @Humanspective: SOURCE (1) Andrea Cerceck Regarding clinical trial research paper - "PD-1 Blockade in Mismatch Repair–Deficient, Locally…
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    April 8, 2025

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  • andrea seghizzi
    @aseghizzi (Twitter)

    @VigilantFox https://t.co/dSAi5V8Gdc
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    April 8, 2025

  • monkeyglasses33
    @monkeyglasses33 (Twitter)

    RT @Humanspective: SOURCE research paper (1) https://t.co/SAKXP1oiY0 https://t.co/oBq3VJXASB
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    April 8, 2025

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  • monkeyglasses33
    @monkeyglasses33 (Twitter)

    RT @Humanspective: SOURCE (1) Andrea Cerceck Regarding clinical trial research paper - "PD-1 Blockade in Mismatch Repair–Deficient, Locally…
    view full post

    April 8, 2025

    16

  • Jackie Lawlor
    @JackieLawlor (Twitter)

    RT @AndreaCercek: Very proud of our study published in @NEJM. 100% clinical complete response with dostarlimab alone in mismatch repair-def…
    view full post

    April 8, 2025

    1091

  • ❤️عشق الشام ( ٢٠٢٤/١٢/٨)
    @sham1567 (Twitter)

    RT @NedaaAlkhamis: دراسة طبية أوردت نتائج مذهلة لعلاج سرطان المستقيم باستخدام الأجسام المضادة وحيدة النسيلة (Monoclonal Antibodies)، سابقة…
    view full post

    April 8, 2025

    7

  • د. نداء الخميس
    @NedaaAlkhamis (Twitter)

    دراسة طبية أوردت نتائج مذهلة لعلاج سرطان المستقيم باستخدام الأجسام المضادة وحيدة النسيلة (Monoclonal Antibodies)، سابقة غير مسبوقة في علاج السرطان. •عنوان الدراسة: PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer •الجهة التي أجرت الدراسة: مركز https://t.co/4zOmKbxh7O
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    April 8, 2025

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  • Andrew Crockett - Australia
    @andrew_crockett (Twitter)

    @SigrunHring @VigilantFox Date on the paper is 2022. https://t.co/i7v7BY4pl1
    view full post

    April 8, 2025

    2

  • Julie Errickson
    @ErricksonJulie (Twitter)

    RT @Humanspective: SOURCE (1) Andrea Cerceck Regarding clinical trial research paper - "PD-1 Blockade in Mismatch Repair–Deficient, Locally…
    view full post

    April 7, 2025

    16

  • BrainbellJangler
    @WaitingForPerot (Twitter)

    @serviceguynj @VigilantFox @RobertKennedyJr The original study was published in June 2022: https://t.co/7XLKNYPWVj Since then, additional work has been done and the treatment was given the green light late last year: https://t.co/B6EfIncWdG This was before RFK Jr got involved. https://t.co/7Gjf83G1ol
    view full post

    April 7, 2025

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  • BrainbellJangler
    @WaitingForPerot (Twitter)

    @STLCards42069 @bimald @VigilantFox The study was first published in June 2022, and was funded in part by the NIH: https://t.co/7XLKNYPWVj https://t.co/O0w7bHO3AL
    view full post

    April 7, 2025

  • Cheryl DeCaire
    @edecaire2979 (Twitter)

    RT @Humanspective: SOURCE research paper (1) https://t.co/SAKXP1oiY0 https://t.co/oBq3VJXASB
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    April 7, 2025

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  • Armed Throbbery
    @ArmedThrobber (Twitter)

    @VigilantFox https://t.co/CZWQJ5f8Dr
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    April 7, 2025

  • Clockwork Orange Magazine
    @kportocali (Twitter)

    RT @Humanspective: SOURCE (1) Andrea Cerceck Regarding clinical trial research paper - "PD-1 Blockade in Mismatch Repair–Deficient, Locally…
    view full post

    April 1, 2025

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  • Piotr Rieske
    @rieske_piotr (Twitter)

    Miejmy nadzieję, że dla pacjentów z rakiem jelita grubego (odbytu) związanym z mutacjami genów naprawy uszkodzeń DNA, ta terapia okaże się tak skuteczna jak imatinib w PBS. Ale to nie są najczęstsze raki jelita grubego. https://t.co/HYmyLuARnO
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    February 22, 2025

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  • Dr. Nina Niu Sanford
    @NiuSanford (Twitter)

    @sujanapriya Based on MSKCC dostarlimab study. Update presented at ASCO 2024 I believe w 40+ patients, still 100% CR. Azur 1 trial completed not yet reported. All not randomized trials but most would not have equipoise at this pt for RCT. https://t.co/t9OAT4lpHk
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    February 5, 2025

  • gerfaud
    @Gerfaud07 (Twitter)

    @Pr_Chabriere_E exemple; cet article montre la disparition sous traitement d'une forme particulière de tumeur rectale chez 12 patients sur 12. le NEJM le publie à juste titre en 2022 https://t.co/a7grKIhI1G
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    January 10, 2025

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  • FORVET
    @KopruTahta11005 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
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    January 8, 2025

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  • MolBio_Concepts_News_Updates
    @newincancer (Twitter)

    Dostarlimab (GSK), एक एंटी-PD1 एंटीबॉडी को स्थानीय रूप से उन्नत dMMR/MSI-H रेक्टल कैंसर के लिए दिसंबर 2024 में ब्रेकथ्रू थेरेपी पदनाम से सम्मानित किया गया था। मूल शोध लेख एनईजेएम, 2022 (https://t.co/tAnZorpcYF) में प्रकाशित हुआ।
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    January 4, 2025

  • MolBio_Concepts_News_Updates
    @newincancer (Twitter)

    Dostarlimab (GSK), an anti-PD1 antibody was awarded breakthrough therapy designation in Dec 2024 for locally advanced dMMR/MSI-H rectal cancers. Original research article published in NEJM, 2022 (https://t.co/tAnZorpcYF).
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    January 4, 2025

  • Yemlihan
    @Yemlihan76 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
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    December 27, 2024

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  • mertbiri
    @halilmertalkan (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
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    December 26, 2024

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  • alı ayşe
    @AMuge30304 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
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    December 26, 2024

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  • Frida
    @neyleyekki (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
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    December 26, 2024

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  • Efnan
    @Efnan436706 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
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    December 25, 2024

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  • ysmin
    @ysmin465901 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
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    December 25, 2024

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  • Rukya
    @rukiabbas (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
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    December 25, 2024

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  • каос тхеорй
    @chaostheoryyyyy (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
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    December 25, 2024

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  • Aslan Aslan
    @AslanAslan19819 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
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  • @9216Sahin (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
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  • cem
    @masmavicem1 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
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  • Oğuzhan
    @oguzhanoguz (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
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  • vatandaşın(1)i
    @1vatandas (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
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    December 25, 2024

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  • Başar AKGÜL
    @clown_1983 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • ziraatfa
    @ziraatfa (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • RB
    @RasitBaysal007 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • Hasan Korkmaz
    @Kuzgungunes1912 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • 06mevlut
    @mevlut06eyt (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • Kazım Alkan
    @kazimalkan64 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • Muzaffer Yasa
    @muzafferyasa (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • mikailuzala
    @mikailuzala (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • Dilek Gürel
    @dilek_gurel_19 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • Ahmet
    @marginalarter (Twitter)

    @AdelinaSfishta Orjinal makale: https://t.co/rhHlOgHinW
    view full post

    December 25, 2024

    1

  • Yasin YILDIZ
    @_yasince (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • RUH HASTASI
    @RUHHASTASI6161 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • Yakup Taşci
    @Avykptsc (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • wifmot
    @cevik62604 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • Mazhar Ozmen
    @MazharOzme68579 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • GulS
    @gulse1905gs (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • ruben frihet
    @FrihetRube75981 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • Halil
    @Halil_izmitli (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • Yonkers
    @caferozkaya41 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • Neslihan
    @Nesliha68813199 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • hakan
    @hakan21058088 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • kamil kayaş
    @kamiL_Kys (Twitter)

    RT @ilyassahinMD: T:
    view full post

    December 25, 2024

    11

  • DURSUNALİRİZELİ
    @Siyahkarga1962 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    269

  • ozan yaralı
    @ozanyar27 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • ibrahim çetin
    @ibrahim00103416 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • Ayten Elidar
    @elidar_ayt31235 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • Fatih
    @fatihaksu19 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • Selim Siyami Uz
    @SiyamiUz (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • İbrahim Dinçer
    @idincer17 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • Avukat cihangir Cayrancı-Law
    @avukatcihangir (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • serdarari
    @serdarari1966 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • kardelen
    @Zeynep66059047 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • Xen Oz
    @xen_oz (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • metin karaduman
    @metinKARADUMAN (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • Alp Batur
    @Batur237077 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • Tuna R.
    @Tuna_r0 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • carpe_diem_
    @tarykyalcin (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • M.Taner ÇELİKSOY
    @TanerCeliksoy (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • Deniz Cem
    @DenizCemM (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • pudu
    @TezTezbahar (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • Ümit İŞBAKAN
    @umitisbakan52 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • YurdaerDemiralp
    @YurdaerDemiralp (Twitter)

    RT @DrGunerSonmez: Küçük bir araştırma ama şimdiye kadar duyulmamış muhteşem bir sonuç; •Kolorektal (kalın bağırsak-makat) kanseri olan 12…
    view full post

    December 25, 2024

    803

  • Stellarslap
    @stellarslap (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • Ersin
    @eyagmur63 (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • Alaattin CEREN
    @alaattinceren (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • Y/C
    @27Yucer (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • odun
    @neopojen (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • Khryst
    @LesiaPiaza (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • MEHMET L. K.
    @memetlutfukinag (Twitter)

    RT @AdelinaSfishta: Haberde 2 link var onları buraya koydum.. ABD ilgili birimi onaylamış, satışa konmuş.. https://t.co/tt21V9VHMF https://…
    view full post

    December 25, 2024

    274

  • Biologist *nostraydogs
    @no_straydogs_ (Twitter)

    RT @drkaanyl: Yeni bir çalışmada: Rektal kanserde bir tek immunoterapi ilacı ile yüzde yüz başarı elde edildi. Cerrahi yok, kemoterapi yok,…
    view full post

    December 25, 2024

    25

  • サイエンスあれこれ
    @sarekore (Twitter)

    毎年約 46,220 人が直腸がんと診断されており、そのうち最大 10% が 局所進行性dMMR/MSI-H 直腸がんです。https://t.co/NBF7eaz8Js
    view full post

    December 22, 2024

  • Tatyana Shamliyan
    @ShamliyanTA (Twitter)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | New England Journal of Medicine https://t.co/6IEH5QuoOD https://t.co/NIoZRoiP2P
    view full post

    November 20, 2024

  • Zeyad Yassin
    @0zeyad_yassin0 (Twitter)

    @Marzouk_Khawaga موضوع ال microbiome ده معقد جدا أنا كنت بقرأ في بيبر (PD-1 Blockade in Mismatch Repair–Deficient, Locally) Advanced Rectal Cancer) وكانت بتقول إن ممكن يكون سبب استجابة النوع ده من الورم للعلاج بنسبة كبيرة عن غيره هو تأثير ال gut microbiome https://t.co/Wy1Yuh8HXS
    view full post

    November 10, 2024

    1

  • Red Piller
    @itsvikasgupta (Twitter)

    RT @Humanspective: SOURCE (1) Andrea Cerceck Regarding clinical trial research paper - "PD-1 Blockade in Mismatch Repair–Deficient, Locally…
    view full post

    September 9, 2024

    16

  • HCH
    @Sammy20545318 (Twitter)

    RT @Humanspective: SOURCE (1) Andrea Cerceck Regarding clinical trial research paper - "PD-1 Blockade in Mismatch Repair–Deficient, Locally…
    view full post

    September 9, 2024

    16

  • Tyee
    @Tyee2012 (Twitter)

    RT @Humanspective: SOURCE (1) Andrea Cerceck Regarding clinical trial research paper - "PD-1 Blockade in Mismatch Repair–Deficient, Locally…
    view full post

    September 4, 2024

    16

  • Sandra Fredrick
    @SandraFredrick (Twitter)

    RT @Humanspective: SOURCE (1) Andrea Cerceck Regarding clinical trial research paper - "PD-1 Blockade in Mismatch Repair–Deficient, Locally…
    view full post

    August 31, 2024

    16

  • Dr. Adam Middleton
    @DrAdamMiddleto1 (Twitter)

    RT @Humanspective: SOURCE (1) Andrea Cerceck Regarding clinical trial research paper - "PD-1 Blockade in Mismatch Repair–Deficient, Locally…
    view full post

    August 23, 2024

    16

  • Bob Von Bruns
    @bobv48 (Twitter)

    RT @Humanspective: SOURCE (1) Andrea Cerceck Regarding clinical trial research paper - "PD-1 Blockade in Mismatch Repair–Deficient, Locally…
    view full post

    August 19, 2024

    16

  • Tammy
    @Tammy6061040277 (Twitter)

    RT @Humanspective: SOURCE (1) Andrea Cerceck Regarding clinical trial research paper - "PD-1 Blockade in Mismatch Repair–Deficient, Locally…
    view full post

    August 19, 2024

    16

  • Joe
    @JEB_i (Twitter)

    This will not help with the quadrennial pain-in-the-ass of election cycles. ‘Unprecedented’, ‘Remarkable’: Cancer Study Leaves Every Patient Cancer-Free https://t.co/AEStmcfHCQ PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer https://t.co/plZMc5WNOr
    view full post

    August 17, 2024

  • Mark Rosanova
    @Drexcimer (Twitter)

    RT @Humanspective: SOURCE (1) Andrea Cerceck Regarding clinical trial research paper - "PD-1 Blockade in Mismatch Repair–Deficient, Locally…
    view full post

    August 15, 2024

    16

  • Humanspective
    @Humanspective (Twitter)

    SOURCE (1) Andrea Cerceck Regarding clinical trial research paper - "PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer" "Such incredible efficacy, with really almost no toxicity" https://t.co/YlItz6TYaz
    view full post

    August 15, 2024

    42

    16

  • Zer07JK
    @ZER07_JK (Twitter)

    @HartvNL Kunt de informatie mogelijk doorgeven? https://t.co/ZgQi7ueuTe New England Journal of Medicine PD-1 blockade in mismatch Repair-Deficient, Locally Advanced Rectal Cancer.
    view full post

    August 6, 2024

    1

  • Zer07JK
    @ZER07_JK (Twitter)

    @lmschrijver Ik hoop dat u dit nog onder ogen komt. https://t.co/ZgQi7ueuTe "New England of Medicine PD-1 Blockade in mismatch repair-deficient, locally advanced rectal cancer.
    view full post

    August 6, 2024

    1

  • john ogrady
    @ogradysays (Twitter)

    This looks promising ⁦@DrJohnCampbell3⁩ PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | New England Journal of Medicine https://t.co/Y1i8pm87p7
    view full post

    July 4, 2024

    1

  • Whiskey Dale
    @Whiskey_Dale (Twitter)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | New England Journal of Medicine https://t.co/eNQPNvA9ln
    view full post

    June 24, 2024

  • Dr. Brad Reinfeld, MD PhD
    @BReinfeld (Twitter)

    @brian_rini @TresUramigas @Uromigos @neerajaiims @TiansterZhang @HHammersMD @tompowles1 @montypal Older (2020, ICIs move so fast!) review but concepts remain the same! https://t.co/O8fwsaozVQ benefit is seen in non melanoma tumors as well! https://t.co/w9kODUyxIM a trial in RCC is a must!
    view full post

    June 2, 2024

    1

  • Bat Pitt
    @mannilotrader (Twitter)

    DOSTARLIMAB anti-PD-1 Monoclonal antibody phase 2 study in which single-agent dostarlimab, an anti–PD-1 monoclonal antibody PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer https://t.co/sGcw0xwU40
    view full post

    June 1, 2024

  • James
    @Product_007 (Twitter)

    ALL 12 patients with locally advanced rectal cancer had a clinical complete response with no evidence of tumors. No invasive surgery, no radiation, no chemotherapy. This is literally a cure for cancer! https://t.co/2HDfuDaW6D
    view full post

    May 28, 2024

  • Lily
    @Lily4Lily2 (Twitter)

    100% remissie van kanker bereikt bij ALLE patiënten in baanbrekend onderzoek bij Rectale Kanker PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer https://t.co/pkkIMbdFik https://t.co/Nd4oeNSa7Y
    view full post

    May 26, 2024

    4

  • chris bolles
    @bolles_chris33 (Twitter)

    ⁦@HedgeyeHC⁩ PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | New England Journal of Medicine https://t.co/QHyxAEkfIB
    view full post

    May 25, 2024

  • John Maki
    @John_W_Maki (Twitter)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | New England Journal of Medicine https://t.co/zMh5MFuUzK
    view full post

    May 25, 2024

  • Andrea Apolo, M.D.
    @apolo_andrea (Twitter)

    RT @EliasChandran: dMMR / MSI-H tumors express more neoantigens, making them more immunogenic. Recent trials have shown exquisite sensitivi…
    view full post

    May 1, 2024

    1

  • Elias Chandran, MBBS
    @EliasChandran (Twitter)

    dMMR / MSI-H tumors express more neoantigens, making them more immunogenic. Recent trials have shown exquisite sensitivity of localized dMMR / MSI-H rectal and colon cancer to immune checkpoint inhibitors. https://t.co/LsP8T4hNDs https://t.co/Mea900LDZl
    view full post

    April 30, 2024

    2

    1

  • ごはん
    @tamanegiR41120 (Twitter)

    RT @Tamama0306: PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer https://t.co/clCmLkPzWc
    view full post

    April 20, 2024

    3

  • まひる
    @mahiru_tk (Twitter)

    RT @Tamama0306: PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer https://t.co/clCmLkPzWc
    view full post

    April 20, 2024

    3

  • mili mili
    @milimil10525873 (Twitter)

    RT @Tamama0306: PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer https://t.co/clCmLkPzWc
    view full post

    April 19, 2024

    3

  • タマホイ
    @Tamama0306 (Twitter)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer https://t.co/clCmLkPzWc
    view full post

    April 19, 2024

    16

    3

  • A
    @highoncoffeine (Twitter)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | New England Journal of Medicine https://t.co/M2tI7CyQB0
    view full post

    April 17, 2024

  • Cristina Wonder
    @Wondercri1982 (Twitter)

    Trovata una cura efficace al 100% per il cancro in uno studio clinico Questi pazienti non hanno ricevuto chemio, radioterapia e intervento chirurgico. Ciò che è inquietante è che lo studio è stato pubblicato 2022 e non sembra aver fatto notizia https://t.co/E2ApPCIEWQ https://t.co/sjK0kZs0n4
    view full post

    April 9, 2024

    1

  • ANNA
    @ANNACippiu (Twitter)

    https://t.co/xLSRurvZyQ
    view full post

    April 8, 2024

  • Thomas Stelter
    @stelter_th39394 (Twitter)

    The original source from post below: PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | New England Journal of Medicine https://t.co/CvciPKxzIE
    view full post

    April 7, 2024

  • JRS-Tabarnia
    @barnablues (Twitter)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | New England Journal of Medicine https://t.co/5dHD3mUHoZ
    view full post

    April 7, 2024

  • Ronald Vandenboom
    @twiddledee1 (Twitter)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | New England Journal of Medicine https://t.co/MQZomqFiKH
    view full post

    April 7, 2024

  • John Hancock
    @JohnHan28576306 (Twitter)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | New England Journal of Medicine https://t.co/1NdhngUv44
    view full post

    April 7, 2024

    2

  • Fay Moore
    @MooreFay (Twitter)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | New England Journal of Medicine https://t.co/DsNMK64A56 This is promising. 100% "cure" in clinical trial of 12.
    view full post

    April 6, 2024

  • MountStHelen
    @HelenY55598508 (Twitter)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | New England Journal of Medicine https://t.co/mmqZsBpL0P
    view full post

    April 6, 2024

  • poetic justice
    @EplurebusUnum (Twitter)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | New England Journal of Medicine. 100% remission rates in new cancer drug https://t.co/bn8T6K1HFF
    view full post

    April 5, 2024

  • Valerie
    @ValerieVirtues (Twitter)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | New England Journal of Medicine https://t.co/qQoemaD0Pu
    view full post

    April 5, 2024

  • Marc Veldhoen
    @marcveld.bsky.social (Bluesky)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer Phase 2, clinical trial. 12 patients, 100% success rate in the treatment group of 6. www.nejm.org/doi/ful... 1/4
    view full post

    April 5, 2024

    4

    1

  • dkirk
    @DK1RK (Twitter)

    @VigilantFox @VPrasadMDMPH here is the study @VPrasadMDMPH https://t.co/VBoEzQuXAx
    view full post

    April 5, 2024

  • Joseph Malloy
    @KearsargeRacing (Twitter)

    RT @KearsargeRacing: @VigilantFox @VigilantFox @zerohedge PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer https…
    view full post

    April 5, 2024

    1

  • Joseph Malloy
    @KearsargeRacing (Twitter)

    @VigilantFox @VigilantFox @zerohedge PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer https://t.co/z1hHJRb6P2
    view full post

    April 5, 2024

    1

    1

  • Beth Brown
    @blacktyperace (Twitter)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | New England Journal of Medicine https://t.co/2eqwXwd88A
    view full post

    April 5, 2024

  • m16
    @m16tri (Twitter)

    臨床試驗中發現前所未有的 100% 治癒癌症方法
    view full post

    April 5, 2024

  • Herc
    @Herc_ster (Twitter)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | New England Journal of Medicine https://t.co/aRMuwUCHxi "All 12 patients (100%; 95% confidence interval, 74 to 100) had a clinical complete response, with no evidence of tumor"
    view full post

    April 5, 2024

  • Mark Stephens
    @alketamark (Twitter)

    @VigilantFox https://t.co/bfJYwyGKUj
    view full post

    April 4, 2024

  • Georgia
    @Heavenforreal (Twitter)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | New England Journal of Medicine https://t.co/f2oeLL84jV
    view full post

    April 4, 2024

  • James Lovinsky
    @JamesLovinsky (Twitter)

    @jwilkstn Yep looks like it: https://t.co/W04WYTEJnM Not very fresh news I guess... but still encouraging! Will have to go digging now and see if there are any newer studies
    view full post

    April 4, 2024

  • Ali Guner
    @AliGunerMD (Twitter)

    RT @5_utr: @f2harrell Excellent point! I’m still stunned treatment guidelines were changed for rectal cancer based on an n=12 single arm tr…
    view full post

    January 18, 2024

    1

  • M. Bolton
    @5_utr (Twitter)

    @f2harrell Excellent point! I’m still stunned treatment guidelines were changed for rectal cancer based on an n=12 single arm trial; it got NEJM publication and immediately inserted into treatment guidelines
    view full post

    January 18, 2024

    4

    1

  • Diego A.R. ⚯͛
    @AngelesRomD (Twitter)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer https://t.co/xdMjoBF0Y8 https://t.co/dVsEQgMiEA
    view full post

    October 27, 2023

  • Tony Felefly
    @TonyFelefly (Twitter)

    @ProtonStorey @DrewMoghanaki @NCCN https://t.co/rCy783BVzk This is the NEJM paper. I am not aware of other relevant data. Is there any other higher quality trial I am missing?
    view full post

    October 25, 2023

    2

  • Lucinda Ayala
    @LucindaAya77404 (Twitter)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer https://t.co/IsqS7xEPxI
    view full post

    September 27, 2023

  • St2B
    @st2b_luckyclove (Twitter)

    ・さらに術前ICIは全身的な抗腫瘍免疫の促進に加え、切除の観点でもプラスとなる可能性あり
    view full post

    August 18, 2023

    2

  • Jovita Mezquita Pla
    @JovitaMezquita (Twitter)

    Un resultat sorprenent i positiu q permetra progressar en el coneixement i tractament del càncer. Ref. Cercek A, Lumish M, et al. PD-1 Blockade in Mismatch Repair-Deficient, Locally Advanced Rectal Cancer. N Engl J Med. 2022;386(25):2363-2376.doi: 10.1056/NEJMoa2201445.
    view full post

    May 19, 2023

  • M. Bolton
    @5_utr (Twitter)

    @DrToddLee @NiuSanford And yet we have celebrations in NEJM about n=12 Funded by the drug manufacturer. Why do people respect this journal? https://t.co/TlsqThxyur
    view full post

    March 21, 2023

    2

  • Leo Tallafigo Moreno
    @TallafigoL (Twitter)

    RT @Rob__Brierley: Findings in keeping with: -Dostarlimab (#rectalcancer) -https://t.co/klztJwjQpY @NEJM - PICC (#colorectalcancer) -htt…
    view full post

    March 2, 2023

    1

  • Rob Brierley
    @Rob__Brierley (Twitter)

    Findings in keeping with: -Dostarlimab (#rectalcancer) -https://t.co/klztJwjQpY @NEJM - PICC (#colorectalcancer) -https://t.co/2J7MoTcH6I @LancetGastroHep - NICHE (colon cancer) https://t.co/Qh4roh0bnh @NatureMedicine #gitwitter #crcsm #onctwitter
    view full post

    March 2, 2023

    2

    1

  • Giovannita Partida
    @Gio_partida (Twitter)

    RT @VivekSubbiah: PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer. COMPLETE RESPOSNES in 12/12 patients. Paradig…
    view full post

    January 2, 2023

    9

  • ×SymphonicSc4lpel×™
    @throwingscalpel (Twitter)

    RT @VivekSubbiah: PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer. COMPLETE RESPOSNES in 12/12 patients. Paradig…
    view full post

    January 1, 2023

    9

  • Dr. Shashank Joshi
    @AskDrShashank (Twitter)

    RT @VivekSubbiah: PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer. COMPLETE RESPOSNES in 12/12 patients. Paradig…
    view full post

    December 31, 2022

    9

  • Tae Hoon Kim
    @taehoonkim (Twitter)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | NEJM https://t.co/3rDd4897ri
    view full post

    December 31, 2022

  • OnColinology
    @ColinGiacobi (Twitter)

    RT @VivekSubbiah: PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer. COMPLETE RESPOSNES in 12/12 patients. Paradig…
    view full post

    December 31, 2022

    9

  • Dr Nabila Ansari
    @nabsansari (Twitter)

    RT @VivekSubbiah: PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer. COMPLETE RESPOSNES in 12/12 patients. Paradig…
    view full post

    December 31, 2022

    9

  • Ming "Tommy" Tang
    @tangming2005 (Twitter)

    RT @VivekSubbiah: PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer. COMPLETE RESPOSNES in 12/12 patients. Paradig…
    view full post

    December 31, 2022

    9

  • A.n.n.
    @fireflyann (Twitter)

    RT @VivekSubbiah: PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer. COMPLETE RESPOSNES in 12/12 patients. Paradig…
    view full post

    December 31, 2022

    9

  • Abraham Lincoln
    @pastamarone (Twitter)

    RT @VivekSubbiah: PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer. COMPLETE RESPOSNES in 12/12 patients. Paradig…
    view full post

    December 31, 2022

    9

  • Petros Grivas
    @PGrivasMDPhD (Twitter)

    RT @VivekSubbiah: PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer. COMPLETE RESPOSNES in 12/12 patients. Paradig…
    view full post

    December 31, 2022

    9

  • Vivek Subbiah, MD
    @VivekSubbiah (Twitter)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer. COMPLETE RESPOSNES in 12/12 patients. Paradigm changing study @NEJM @AndreaCercek @Dr_R_Kurzrock https://t.co/oLZQt04a3O https://t.co/kzUcb9aP5q
    view full post

    December 31, 2022

    61

    9

  • Devo MAAA- Make America America Again
    @DevinDevo1060 (Twitter)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | NEJM Just read a article in the Times, about this medical test, that led to complete recovery for all tested for rectal cancer. Shouldn’t this be BIG news? https://t.co/6BohucOZlx
    view full post

    December 31, 2022

  • Saiful Hidayat
    @hidayat_sai (Twitter)

    @pinnotyo https://t.co/g7T7okRZeV
    view full post

    December 29, 2022

  • Sue Velez
    @SueVelez19 (Twitter)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | NEJM https://t.co/T6p6Wi5Jr1
    view full post

    December 26, 2022

  • ARYAN®
    @gladeolie (Twitter)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer https://t.co/MH55EIHRmp
    view full post

    December 21, 2022

  • SpeakForReason
    @iSpeakForReason (Twitter)

    12 patients in study rec’d monoclonal antibodies for rectal cancer stage 2 & 3; ALL 12 patients cured. PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | NEJM https://t.co/jWAHIFtz9m
    view full post

    December 15, 2022

  • Rosa Parreño
    @casiopea1971 (Twitter)

    RT @CGAIGC:
    view full post

    December 10, 2022

    8

  • Megha Ranganathan
    @meghar111 (Twitter)

    RT @CGAIGC:
    view full post

    December 1, 2022

    8

  • Laura Valle
    @LValleResearch (Twitter)

    RT @CGAIGC:
    view full post

    November 29, 2022

    8

  • Ed Esplin, MD, PhD
    @EdEsplin (Twitter)

    RT @CGAIGC:
    view full post

    November 29, 2022

    8

  • Asaf Maoz
    @asaf_maoz (Twitter)

    RT @CGAIGC:
    view full post

    November 29, 2022

    8

  • Swati G. Patel, MD MS
    @swatigp (Twitter)

    RT @CGAIGC:
    view full post

    November 29, 2022

    8

  • Matt Yurgelun, MD
    @MattYurgelun (Twitter)

    RT @CGAIGC:
    view full post

    November 29, 2022

    8

  • CGA-IGC
    @CGAIGC (Twitter)


    view full post

    November 29, 2022

    15

    8

  • MaKin
    @KiarKini (Twitter)

    Fascinating research. Monoclonal antibody treatment sent cancer into complete remission in every patient treated. Very promising. PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | NEJM https://t.co/4u0OfZRxpX
    view full post

    October 18, 2022

  • 奈良県立医科大学　消化器・代謝内科
    @naraidai_3nai (Twitter)

    今日の抄読会
    view full post

    October 12, 2022

    1

  • Dr. Brad Reinfeld, MD PhD
    @BReinfeld (Twitter)

    @Caroline_Bartma MSI hi and ras+. Or MSI hi and ras- The MSI status has a incredible effect on the tumor immune microenvironment. As seen at ESMO22 and by https://t.co/Mheax8RPM6.
    view full post

    September 16, 2022

  • Mile C.V.
    @MilenaC27356365 (Twitter)

    RT @LuisJaimeCastr3: PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | NEJM https://t.co/MqSPVUFgWH
    view full post

    September 11, 2022

    1

  • Luis J. Castro-Vega
    @LuisJaimeCastr3 (Twitter)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | NEJM https://t.co/MqSPVUFgWH
    view full post

    September 11, 2022

    2

    1

  • Adela
    @adelapoite (Twitter)

    RT @ESTRO_RT: #ESTROnewsletter PD-1 Blockade in Mismatch Repair-Deficient, Locally Advanced Rectal Cancer https://t.co/ALR30qAXQA https://t…
    view full post

    August 22, 2022

    2

  • Calogero Casà
    @LilloCasa (Twitter)

    RT @ESTRO_RT: #ESTROnewsletter PD-1 Blockade in Mismatch Repair-Deficient, Locally Advanced Rectal Cancer https://t.co/ALR30qAXQA https://t…
    view full post

    August 22, 2022

    2

  • ESTRO
    @ESTRO_RT (Twitter)

    #ESTROnewsletter PD-1 Blockade in Mismatch Repair-Deficient, Locally Advanced Rectal Cancer https://t.co/ALR30qAXQA https://t.co/StTYpux0MH
    view full post

    August 22, 2022

    3

    2

  • Mayberry Memorial
    @MMLynchSyndrome (Twitter)

    #LynchFactFriday Dostarlimab, a promising new immunotherapy drug in clinical trials, offers great hope for people with #LynchSyndrome. 6 months from treatment 12 people with rectal cancer no longer showed evidence of tumors.
    view full post

    August 19, 2022

    1

  • Peppe Morano
    @PeppeMorano (Twitter)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | NEJM https://t.co/PFuxK8iGMq
    view full post

    August 8, 2022

  • カス
    @kspharmacist (Twitter)

    [本日の抄読会] dMMR(MSI-H)局所進行直腸癌に対する，PD-1阻害薬dostarlimabによる術前治療を検証した第Ⅱ相試験．MSKCCより． https://t.co/8UQx7c5h7i 16名登録され，全員がCR．手術，放射線省略と．selectionがかかった患者集団ではあるが，薬物治療のみで治せる時代が確実に近づいている様相．
    view full post

    August 1, 2022

  • BioAscend
    @BioAscend (Twitter)

    Hot off the presses--Dr. Patrick Sullivan summarizes the results from the recently published results on PD-1 blockade in mismatch repair deficient, locally advanced rectal cancer at #DDHO2022 https://t.co/M9ysCROyBF
    view full post

    July 22, 2022

    2

  • Jill Genua, MD, FASCRS, FACS
    @drjillgenua (Twitter)

    RT @CGAIGC: We are kicking off July with a #HereditaryGICancer Tweetorial on a hot topic from June, "PD-1 Blockade in Mismatch Repair-Defic…
    view full post

    July 12, 2022

    11

  • Grant Jirka, MD
    @GrantJirka (Twitter)

    Stage II-III rectal cancer with complete response to neoadjuvant immunotherapy alone w/ 12 months follow-up is a big win! Saving patients from typical chemoradiation+surgery. Looking forward to seeing the follow-up results to assess duration of response! https://t.co/wdEK54MINF
    view full post

    July 12, 2022

  • Antonio López Reyes
    @qtnet (Twitter)

    https://t.co/7ILjrAOP0m
    view full post

    July 12, 2022

  • Cathryn Koptiuch
    @CKoptiuch (Twitter)

    RT @CGAIGC: We are kicking off July with a #HereditaryGICancer Tweetorial on a hot topic from June, "PD-1 Blockade in Mismatch Repair-Defic…
    view full post

    July 12, 2022

    11

  • Lona Mody, MD, M.Sc
    @LonaMody (Twitter)

    RT @CGAIGC: We are kicking off July with a #HereditaryGICancer Tweetorial on a hot topic from June, "PD-1 Blockade in Mismatch Repair-Defic…
    view full post

    July 12, 2022

    11

  • Asaf Maoz
    @asaf_maoz (Twitter)

    RT @CGAIGC: We are kicking off July with a #HereditaryGICancer Tweetorial on a hot topic from June, "PD-1 Blockade in Mismatch Repair-Defic…
    view full post

    July 11, 2022

    11

  • Eileen McKay
    @emckaymd (Twitter)

    RT @CGAIGC: We are kicking off July with a #HereditaryGICancer Tweetorial on a hot topic from June, "PD-1 Blockade in Mismatch Repair-Defic…
    view full post

    July 11, 2022

    11

  • Michael Cruise
    @GIlymphomapath (Twitter)

    RT @CGAIGC: We are kicking off July with a #HereditaryGICancer Tweetorial on a hot topic from June, "PD-1 Blockade in Mismatch Repair-Defic…
    view full post

    July 11, 2022

    11

  • Danielle Marino(she/her)
    @drdani23 (Twitter)

    RT @CGAIGC: We are kicking off July with a #HereditaryGICancer Tweetorial on a hot topic from June, "PD-1 Blockade in Mismatch Repair-Defic…
    view full post

    July 11, 2022

    11

  • A.n.n.
    @fireflyann (Twitter)

    RT @CGAIGC: We are kicking off July with a #HereditaryGICancer Tweetorial on a hot topic from June, "PD-1 Blockade in Mismatch Repair-Defic…
    view full post

    July 11, 2022

    11

  • MSK Department of Medicine
    @MSK_DeptOfMed (Twitter)

    RT @digitalsci: Making news: according to @altmetric, this colorectal #cancer research from @MSKCancerCenter - presented at @ASCO 2022 and…
    view full post

    July 5, 2022

    4

  • lmperkins
    @lmperkins (Twitter)

    RT @digitalsci: Making news: according to @altmetric, this colorectal #cancer research from @MSKCancerCenter - presented at @ASCO 2022 and…
    view full post

    July 5, 2022

    4

  • Altmetric
    @altmetric (Twitter)

    RT @digitalsci: Making news: according to @altmetric, this colorectal #cancer research from @MSKCancerCenter - presented at @ASCO 2022 and…
    view full post

    July 5, 2022

    4

  • Digital Science
    @digitalsci (Twitter)

    Making news: according to @altmetric, this colorectal #cancer research from @MSKCancerCenter - presented at @ASCO 2022 and published in @NEJM - has attracted the most attention of any non-COVID paper published last month: https://t.co/kguRTvOH6u @AndreaCercek #ASCO2022 https://t.co/QipE6VU8cs
    view full post

    July 5, 2022

    10

    4

  • Espi
    @EspinosaCrsiete (Twitter)

    RT @Shine_McShine: 2/ En primer lugar es de agradecer que, para variar, el periodista haya enlazado el artículo del que habla. Es este de a…
    view full post

    July 3, 2022

    27

  • Yoshihisa Okazaki
    @XX62 (Twitter)

    早川智先生FBより。論文になったようです。https://t.co/i3EwhlS8K7
    view full post

    June 30, 2022

    1

  • 海路海斗
    @M3fOAzGv6OtvOVE (Twitter)

    RT @francescodamil6: 元論文はこちらからhttps://t.co/HUytS5vLE9
    view full post

    June 30, 2022

    3

  • うさみつ
    @mitu02769550 (Twitter)

    RT @francescodamil6: 元論文はこちらからhttps://t.co/HUytS5vLE9
    view full post

    June 30, 2022

    3

  • 早川　智@コロナウイルス対策には正しい情報を！
    @francescodamil6 (Twitter)

    元論文はこちらからhttps://t.co/HUytS5vLE9
    view full post

    June 30, 2022

    18

    3

  • Digmyself
    @gahawoolah (Twitter)

    RT @cancer_evolve: COLORECTAL: in a small study (n=12) of microsatellite unstable locally advanced rectal cancer, neoadjuvant PD-1 inhibiti…
    view full post

    June 25, 2022

    3

  • Jonathan
    @LookItsJonathan (Twitter)

    RT @cancer_evolve: COLORECTAL: in a small study (n=12) of microsatellite unstable locally advanced rectal cancer, neoadjuvant PD-1 inhibiti…
    view full post

    June 21, 2022

    3

  • ブライトン
    @okiyonma (Twitter)

    RT @yukitsugu1963: PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | NEJM https://t.co/DMiEjxmUz7 投与した１２人全てPET…
    view full post

    June 20, 2022

    1

  • 血液内科医　中村　幸嗣
    @yukitsugu1963 (Twitter)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | NEJM https://t.co/DMiEjxmUz7 投与した１２人全てPET陰性！多分治癒！ がんの種類の厳密な区別は必要 でもこれはすごいこと https://t.co/vrobDYJRJ2
    view full post

    June 20, 2022

    8

    1

  • Tevfik Ergül
    @tergul06 (Twitter)

    RT @cancer_evolve: COLORECTAL: in a small study (n=12) of microsatellite unstable locally advanced rectal cancer, neoadjuvant PD-1 inhibiti…
    view full post

    June 20, 2022

    3

  • Cancer_Evolve
    @cancer_evolve (Twitter)

    COLORECTAL: in a small study (n=12) of microsatellite unstable locally advanced rectal cancer, neoadjuvant PD-1 inhibition (dostarlimab) delivered 100% CR rate (all PET-negative); no patients have subsequently progressed (follow up 6 - 25 months). https://t.co/QkAQE9udWm
    view full post

    June 20, 2022

    3

    3

  • Kenji Okumura
    @KenjiOkumura_MD (Twitter)

    Impressive results. PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | NEJM https://t.co/y28eOMfb8o
    view full post

    June 19, 2022

  • kazuki.o
    @akazukinn318 (Twitter)

    話題のやつ、有料で読めんけど大学でなら読めるんかな https://t.co/fOEOdnC7oK
    view full post

    June 17, 2022

    1

  • Varun Bansal
    @Varun_VBSurg (Twitter)

    RT @RajivSarin5: Media Sensation on Rectal Cancers vanishing with Immuno drug Dostarlimab without Surgery/Radiatn/Chemo Its a signal getti…
    view full post

    June 17, 2022

    25

  • ゆたのーる
    @Yuthanol (Twitter)

    https://t.co/G3zHxXwBBO
    view full post

    June 16, 2022

  • Ozzy
    @ozzybanks_ (Twitter)

    RT @RajivSarin5: Media Sensation on Rectal Cancers vanishing with Immuno drug Dostarlimab without Surgery/Radiatn/Chemo Its a signal getti…
    view full post

    June 15, 2022

    25

  • Rashmi Dalvi
    @RashmiDalvi3 (Twitter)

    RT @RajivSarin5: Media Sensation on Rectal Cancers vanishing with Immuno drug Dostarlimab without Surgery/Radiatn/Chemo Its a signal getti…
    view full post

    June 14, 2022

    25

  • Tina de Toetterbeck7jabs
    @Toetterbeck (Twitter)

    RT @Aiims1742: The rest as they say is history. Kudos for recognizing the importance of a single exceptional responder amidst near universa…
    view full post

    June 14, 2022

    3

  • Vivien Marx
    @metricausa (Twitter)

    RT @Aiims1742: The rest as they say is history. Kudos for recognizing the importance of a single exceptional responder amidst near universa…
    view full post

    June 14, 2022

    3

  • Dr. Birep Aygün
    @genperisi (Twitter)

    RT @Aiims1742: The rest as they say is history. Kudos for recognizing the importance of a single exceptional responder amidst near universa…
    view full post

    June 14, 2022

    3

  • Anirban Maitra
    @Aiims1742 (Twitter)

    The rest as they say is history. Kudos for recognizing the importance of a single exceptional responder amidst near universal lack of response to aPD-1 monotherapy in #ColorectalCancer. That observation continues to be leveraged in this genetic subset: https://t.co/pgWYbCtTD5
    view full post

    June 14, 2022

    30

    3

  • Camilo J. Llamoza-Torres
    @CamiloJT (Twitter)

    RT @aegastro:
    view full post

    June 13, 2022

    3

  • Angeles Perez Aisa
    @drapereza (Twitter)

    RT @aegastro:
    view full post

    June 13, 2022

    3

  • Gaurav Sharma, MD
    @hemeonc_doc (Twitter)

    100% complete clinical response with dostarlimab in stage II or III rectal adenocarcinoma. https://t.co/PhJDfc6xQD @NEJM @MSKCancerCenter
    view full post

    June 12, 2022

    2

  • Pilar Garcia-Iglesias
    @Amleto3333 (Twitter)

    RT @aegastro:
    view full post

    June 12, 2022

    3

  • Junaid
    @JunaidMahlik (Twitter)

    RT @RajivSarin5: Media Sensation on Rectal Cancers vanishing with Immuno drug Dostarlimab without Surgery/Radiatn/Chemo Its a signal getti…
    view full post

    June 12, 2022

    25

  • Carlitos
    @Carlito69374883 (Twitter)

    https://t.co/gUziWx5U1H
    view full post

    June 11, 2022

  • Naeimeh Hosseini
    @naeimhos (Twitter)

    RT @KordastiL: A complete response to PD-1 blockade in all 12 patients with locally advanced rectal cancer! no surgery or chemo is needed a…
    view full post

    June 11, 2022

    4

  • GASTROCELAYA
    @GASTROCELAYA (Twitter)

    PD-1 Blockade in Mismatch Repair-Deficient, Locally Advanced Rectal Cancer - PubMed. El artículo del qu todos hablan. https://t.co/z9KSmJyiGC
    view full post

    June 11, 2022

  • Aegastro
    @aegastro (Twitter)


    view full post

    June 11, 2022

    5

    3

  • RCHPediatrics
    @RchPediatrics (Twitter)

    RT @RajivSarin5: Media Sensation on Rectal Cancers vanishing with Immuno drug Dostarlimab without Surgery/Radiatn/Chemo Its a signal getti…
    view full post

    June 10, 2022

    25

  • fenta
    @solensagy (Twitter)

    @arimtorresa @Sbeah Lo encontreeee https://t.co/waHyxSLEBU
    view full post

    June 10, 2022

    2

  • Steven D Wexner MD, PhD
    @SWexner (Twitter)

    Thank you @WPLGLocal10 for disseminating this very innovative, exciting, and potentially paradigm-shifting #colorectalsurgery #colorectalcancer information from @NEJM https://t.co/IrIVFQmCM7 https://t.co/av37SNmZ0I
    view full post

    June 10, 2022

    5

    1

  • Erdembat Enkhjargal
    @tuulaitmg (Twitter)

    АНУ-Д ХОРТ ХАВДРН ЭСРЭГ ТАРИАНЫ ТУРШИЛТАД ОРОЛЦСОН БҮХ ӨВЧТӨН БҮРЭН ЭДГЭРЧЭЭ!АНУд хгдсэн эмнэл зүйн туршилтр достарлимаб хэмх эмн бэлдмэл н туршилтад хамрагдсан өвчтөн бүрн хорт хавдрг амжилттай устгасан бн. https://t.co/uiNW55BV5o ~copy https://t.co/9CuwVbZuM3
    view full post

    June 10, 2022

  • Chetanya Pandya
    @ChetanyaPandya (Twitter)

    RT @RajivSarin5: Media Sensation on Rectal Cancers vanishing with Immuno drug Dostarlimab without Surgery/Radiatn/Chemo Its a signal getti…
    view full post

    June 10, 2022

    25

  • Ashley
    @ashley_asya (Twitter)

    RT @RajivSarin5: Media Sensation on Rectal Cancers vanishing with Immuno drug Dostarlimab without Surgery/Radiatn/Chemo Its a signal getti…
    view full post

    June 10, 2022

    25

  • तिलानो
    @dukhinepal (Twitter)

    @lomo1910 @prbanjade https://t.co/xXJDVpJCwe
    view full post

    June 10, 2022

  • Билэг.
    @bileg_999 (Twitter)

    RT @moogii0305: АНУ-Д ХОРТ ХАВДРЫН ЭСРЭГ ТАРИАНЫ ТУРШИЛТАД ОРОЛЦСОН БҮХ ӨВЧТӨН БҮРЭН ЭДГЭРЧЭЭ https://t.co/DRBk8gQ5fd https://t.co/DvyEEY7…
    view full post

    June 10, 2022

    2

  • Oyuna
    @oyunbilegr (Twitter)

    RT @moogii0305: АНУ-Д ХОРТ ХАВДРЫН ЭСРЭГ ТАРИАНЫ ТУРШИЛТАД ОРОЛЦСОН БҮХ ӨВЧТӨН БҮРЭН ЭДГЭРЧЭЭ https://t.co/DRBk8gQ5fd https://t.co/DvyEEY7…
    view full post

    June 10, 2022

    2

  • Мөөгий нь байна өө
    @moogii0305 (Twitter)

    АНУ-Д ХОРТ ХАВДРЫН ЭСРЭГ ТАРИАНЫ ТУРШИЛТАД ОРОЛЦСОН БҮХ ӨВЧТӨН БҮРЭН ЭДГЭРЧЭЭ https://t.co/DRBk8gQ5fd https://t.co/DvyEEY7uLu
    view full post

    June 10, 2022

    3

    2

  • Naïf y diletante
    @brujomonetario (Twitter)

    RT @Shine_McShine: 2/ En primer lugar es de agradecer que, para variar, el periodista haya enlazado el artículo del que habla. Es este de a…
    view full post

    June 10, 2022

    27

  • Isra
    @frohen23 (Twitter)

    RT @Shine_McShine: 2/ En primer lugar es de agradecer que, para variar, el periodista haya enlazado el artículo del que habla. Es este de a…
    view full post

    June 10, 2022

    27

  • 車椅子俥夫【湊屋創輔】
    @sakata37108 (Twitter)

    ガンの免疫療法の最新論文。PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | NEJM #SmartNews https://t.co/9xmu8WouGw
    view full post

    June 10, 2022

  • Dr Anupam Sharma MD, PhD.
    @dranupamsarma (Twitter)

    RT @RajivSarin5: Media Sensation on Rectal Cancers vanishing with Immuno drug Dostarlimab without Surgery/Radiatn/Chemo Its a signal getti…
    view full post

    June 10, 2022

    25

  • Mora de los cojones
    @placaplone (Twitter)

    RT @Shine_McShine: 2/ En primer lugar es de agradecer que, para variar, el periodista haya enlazado el artículo del que habla. Es este de a…
    view full post

    June 10, 2022

    27

  • Сэдбазар Оюун
    @Sedbaz (Twitter)

    АНУ-Д ХОРТ ХАВДРЫН ЭСРЭГ ТАРИАНЫ ТУРШИЛТАД ОРОЛЦСОН БҮХ ӨВЧТӨН БҮРЭН ЭДГЭРЧЭЭ https://t.co/ojOGVomUhS АНУ-д хийгдсэн эмнэл зүйн туршилтаар достарлимаб хэмээх эмийн бэлдмэл нь туршилтад хамрагдсан өвчтөн бүрийн хорт хавдрыг амжилттай устгасан байна.
    view full post

    June 9, 2022

    1

  • Cancerfighters
    @canceramyth (Twitter)

    RT @RajivSarin5: Media Sensation on Rectal Cancers vanishing with Immuno drug Dostarlimab without Surgery/Radiatn/Chemo Its a signal getti…
    view full post

    June 9, 2022

    25

  • Quetzalcoaltl
    @Quetzalcoaltl1 (Twitter)

    RT @Shine_McShine: 2/ En primer lugar es de agradecer que, para variar, el periodista haya enlazado el artículo del que habla. Es este de a…
    view full post

    June 9, 2022

    27

  • Ankush Jajodiaᅠᅠᅠᅠᅠᅠᅠᅠ
    @ankushjaj (Twitter)

    RT @RajivSarin5: Media Sensation on Rectal Cancers vanishing with Immuno drug Dostarlimab without Surgery/Radiatn/Chemo Its a signal getti…
    view full post

    June 9, 2022

    25

  • Pototxo
    @pototxo (Twitter)

    RT @Shine_McShine: 2/ En primer lugar es de agradecer que, para variar, el periodista haya enlazado el artículo del que habla. Es este de a…
    view full post

    June 9, 2022

    27

  • Sol pimentel
    @Solpimentel7 (Twitter)

    RT @Shine_McShine: 2/ En primer lugar es de agradecer que, para variar, el periodista haya enlazado el artículo del que habla. Es este de a…
    view full post

    June 9, 2022

    27

  • Banshee. Sui y Fel son demasiado adorables
    @Banshee_y_etc (Twitter)

    RT @Shine_McShine: 2/ En primer lugar es de agradecer que, para variar, el periodista haya enlazado el artículo del que habla. Es este de a…
    view full post

    June 9, 2022

    27

  • Laura Fresneda#JoNotincRey#17volemsaberlaveritat
    @fresneda_laura (Twitter)

    RT @Shine_McShine: 2/ En primer lugar es de agradecer que, para variar, el periodista haya enlazado el artículo del que habla. Es este de a…
    view full post

    June 9, 2022

    27

  • Jiten Sharma
    @JitenSharma10 (Twitter)

    RT @RajivSarin5: Media Sensation on Rectal Cancers vanishing with Immuno drug Dostarlimab without Surgery/Radiatn/Chemo Its a signal getti…
    view full post

    June 9, 2022

    25

  • César Alonso
    @CsarCesaralonso (Twitter)

    @gallinetas20 https://t.co/fLQOXYG1le
    view full post

    June 9, 2022

  • Okan Kabak
    @OkanKabak (Twitter)

    RT @genetik_muh: Hastaların %20’si belli yan etkiler ile karşılaştı lakin bu yan etkiler kolayca yönetildi. Çalışma henüz küçük bir grup iç…
    view full post

    June 9, 2022

    1

  • Jose Ignacio
    @69nueve (Twitter)

    RT @Shine_McShine: 2/ En primer lugar es de agradecer que, para variar, el periodista haya enlazado el artículo del que habla. Es este de a…
    view full post

    June 9, 2022

    27

  • Young Oncologists Group India
    @IndianYoungOnco (Twitter)

    RT @RajivSarin5: Media Sensation on Rectal Cancers vanishing with Immuno drug Dostarlimab without Surgery/Radiatn/Chemo Its a signal getti…
    view full post

    June 9, 2022

    25

  • Soraya Krüger
    @Soriblack (Twitter)

    RT @realdocdan: Huge day for #oncology! Phase II study @AndreaCercek et al. pub @NEJM: anti-PD1-monoclonal #antibody treatment w/ dostarlim…
    view full post

    June 9, 2022

    1

  • Ayanami Rei
    @FreeMind413 (Twitter)

    RT @chernyvaya: Першоджерело https://t.co/Bj2hnpx2l7
    view full post

    June 9, 2022

    1

  • TS
    @TseM53783433 (Twitter)

    RT @Bolorshuuder: АНУ-Д ХОРТ ХАВДРЫН ЭСРЭГ ТАРИАНЫ ТУРШИЛТАД ОРОЛЦСОН БҮХ ӨВЧТӨН БҮРЭН ЭДГЭРЧЭЭ https://t.co/keBY0ijnPE АНУ-д хийгдсэн эмнэ…
    view full post

    June 9, 2022

    6

  • Antonio López-Fando
    @LopezFando (Twitter)

    RT @Shine_McShine: 2/ En primer lugar es de agradecer que, para variar, el periodista haya enlazado el artículo del que habla. Es este de a…
    view full post

    June 9, 2022

    27

  • Lkhagvasuren
    @LkhagHaguwaa (Twitter)

    RT @Bolorshuuder: АНУ-Д ХОРТ ХАВДРЫН ЭСРЭГ ТАРИАНЫ ТУРШИЛТАД ОРОЛЦСОН БҮХ ӨВЧТӨН БҮРЭН ЭДГЭРЧЭЭ https://t.co/keBY0ijnPE АНУ-д хийгдсэн эмнэ…
    view full post

    June 9, 2022

    6

  • saikia
    @PrasurjiyaS (Twitter)

    RT @RajivSarin5: Media Sensation on Rectal Cancers vanishing with Immuno drug Dostarlimab without Surgery/Radiatn/Chemo Its a signal getti…
    view full post

    June 9, 2022

    25

  • Jesus Gomez
    @jesulito_84 (Twitter)

    RT @Shine_McShine: 2/ En primer lugar es de agradecer que, para variar, el periodista haya enlazado el artículo del que habla. Es este de a…
    view full post

    June 9, 2022

    27

  • Abaddonx
    @abaddonxrdv (Twitter)

    RT @Shine_McShine: 2/ En primer lugar es de agradecer que, para variar, el periodista haya enlazado el artículo del que habla. Es este de a…
    view full post

    June 9, 2022

    27

  • serrgv
    @serrgv (Twitter)

    RT @medical_xpress: Findings from a prospective phase II study with dostarlimab for advanced local rectal #cancer @myesmo @nejm https://t.c…
    view full post

    June 9, 2022

    5

  • ✨Jesi.Uwu✨
    @JesiUwu (Twitter)

    RT @Shine_McShine: 2/ En primer lugar es de agradecer que, para variar, el periodista haya enlazado el artículo del que habla. Es este de a…
    view full post

    June 9, 2022

    27

  • Begz Vanchin
    @BegzV (Twitter)

    RT @Bolorshuuder: АНУ-Д ХОРТ ХАВДРЫН ЭСРЭГ ТАРИАНЫ ТУРШИЛТАД ОРОЛЦСОН БҮХ ӨВЧТӨН БҮРЭН ЭДГЭРЧЭЭ https://t.co/keBY0ijnPE АНУ-д хийгдсэн эмнэ…
    view full post

    June 9, 2022

    6

  • bluepoint
    @castellvi1976 (Twitter)

    RT @Shine_McShine: 2/ En primer lugar es de agradecer que, para variar, el periodista haya enlazado el artículo del que habla. Es este de a…
    view full post

    June 9, 2022

    27

  • Аялагч
    @Unshmaarum (Twitter)

    RT @Bolorshuuder: АНУ-Д ХОРТ ХАВДРЫН ЭСРЭГ ТАРИАНЫ ТУРШИЛТАД ОРОЛЦСОН БҮХ ӨВЧТӨН БҮРЭН ЭДГЭРЧЭЭ https://t.co/keBY0ijnPE АНУ-д хийгдсэн эмнэ…
    view full post

    June 9, 2022

    6

  • tuvshee
    @9tuvshin (Twitter)

    RT @Bolorshuuder: АНУ-Д ХОРТ ХАВДРЫН ЭСРЭГ ТАРИАНЫ ТУРШИЛТАД ОРОЛЦСОН БҮХ ӨВЧТӨН БҮРЭН ЭДГЭРЧЭЭ https://t.co/keBY0ijnPE АНУ-д хийгдсэн эмнэ…
    view full post

    June 9, 2022

    6

  • ☯️
    @Batsuuri_Munkh (Twitter)

    RT @Bolorshuuder: АНУ-Д ХОРТ ХАВДРЫН ЭСРЭГ ТАРИАНЫ ТУРШИЛТАД ОРОЛЦСОН БҮХ ӨВЧТӨН БҮРЭН ЭДГЭРЧЭЭ https://t.co/keBY0ijnPE АНУ-д хийгдсэн эмнэ…
    view full post

    June 9, 2022

    6

  • Болоршүүдэр
    @Bolorshuuder (Twitter)

    АНУ-Д ХОРТ ХАВДРЫН ЭСРЭГ ТАРИАНЫ ТУРШИЛТАД ОРОЛЦСОН БҮХ ӨВЧТӨН БҮРЭН ЭДГЭРЧЭЭ https://t.co/keBY0ijnPE АНУ-д хийгдсэн эмнэл зүйн туршилтаар достарлимаб хэмээх эмийн бэлдмэл нь туршилтад хамрагдсан өвчтөн бүрийн хорт хавдрыг амжилттай устгасан байна.
    view full post

    June 9, 2022

    4

    6

  • Acid Kraken
    @AcidClaus (Twitter)

    RT @ascon_miguel: Increible pero cierto!
    view full post

    June 9, 2022

    1


  • @Dj_Doublep (Twitter)

    RT @Shine_McShine: 2/ En primer lugar es de agradecer que, para variar, el periodista haya enlazado el artículo del que habla. Es este de a…
    view full post

    June 9, 2022

    27

  • Medical Xpress
    @physorg_health (Twitter)

    RT @medical_xpress: Findings from a prospective phase II study with dostarlimab for advanced local rectal #cancer @myesmo @nejm https://t.c…
    view full post

    June 9, 2022

    5

  • Science X
    @sciencex_com (Twitter)

    RT @medical_xpress: Findings from a prospective phase II study with dostarlimab for advanced local rectal #cancer @myesmo @nejm https://t.c…
    view full post

    June 9, 2022

    5

  • Phys.org
    @physorg_com (Twitter)

    RT @medical_xpress: Findings from a prospective phase II study with dostarlimab for advanced local rectal #cancer @myesmo @nejm https://t.c…
    view full post

    June 9, 2022

    5

  • Medical Xpress
    @medical_xpress (Twitter)

    Findings from a prospective phase II study with dostarlimab for advanced local rectal #cancer @myesmo @nejm https://t.co/pZWoEKIBZ0 https://t.co/FMs75P5Z7S
    view full post

    June 9, 2022

    9

    5

  • Miguel Ascon, MS, PhD
    @ascon_miguel (Twitter)

    Increible pero cierto!
    view full post

    June 9, 2022

    2

    1

  • Ça plane pour moi
    @rosvalarg (Twitter)

    RT @Shine_McShine: 2/ En primer lugar es de agradecer que, para variar, el periodista haya enlazado el artículo del que habla. Es este de a…
    view full post

    June 9, 2022

    27

  • Liquid Biopsy Labs
    @LiquidBiopsyNow (Twitter)

    RT @JAX_CKB: Exciting results show all 12 patients with MMR-deficient, locally advanced rectal cancer achieved a complete response to singl…
    view full post

    June 9, 2022

    7

  • Shravan Sharad Nadkarni
    @OncoShravan (Twitter)

    RT @RajivSarin5: Media Sensation on Rectal Cancers vanishing with Immuno drug Dostarlimab without Surgery/Radiatn/Chemo Its a signal getti…
    view full post

    June 9, 2022

    25

  • S Kunju
    @shamim47154521 (Twitter)

    RT @RajivSarin5: Media Sensation on Rectal Cancers vanishing with Immuno drug Dostarlimab without Surgery/Radiatn/Chemo Its a signal getti…
    view full post

    June 9, 2022

    25

  • Neftali
    @Neftali42510295 (Twitter)

    RT @Shine_McShine: 2/ En primer lugar es de agradecer que, para variar, el periodista haya enlazado el artículo del que habla. Es este de a…
    view full post

    June 9, 2022

    27

  • Marta Cabello
    @martona_to (Twitter)

    RT @Shine_McShine: 2/ En primer lugar es de agradecer que, para variar, el periodista haya enlazado el artículo del que habla. Es este de a…
    view full post

    June 9, 2022

    27

  • Sergio Bustamante
    @elsergioj (Twitter)

    RT @Shine_McShine: 2/ En primer lugar es de agradecer que, para variar, el periodista haya enlazado el artículo del que habla. Es este de a…
    view full post

    June 9, 2022

    27

  • Gaurav Narula MD
    @DrGauravNarula (Twitter)

    RT @RajivSarin5: Media Sensation on Rectal Cancers vanishing with Immuno drug Dostarlimab without Surgery/Radiatn/Chemo Its a signal getti…
    view full post

    June 9, 2022

    25

  • ସମୀତ Sameet
    @SameetPanda (Twitter)

    RT @RajivSarin5: Media Sensation on Rectal Cancers vanishing with Immuno drug Dostarlimab without Surgery/Radiatn/Chemo Its a signal getti…
    view full post

    June 9, 2022

    25

  • Ankita Upadhyay
    @ankitaup (Twitter)

    RT @RajivSarin5: Media Sensation on Rectal Cancers vanishing with Immuno drug Dostarlimab without Surgery/Radiatn/Chemo Its a signal getti…
    view full post

    June 9, 2022

    25

  • Banjot Kaur
    @Banjotkaur (Twitter)

    RT @RajivSarin5: Media Sensation on Rectal Cancers vanishing with Immuno drug Dostarlimab without Surgery/Radiatn/Chemo Its a signal getti…
    view full post

    June 9, 2022

    25

  • Yeggy
    @manikbasha2197 (Twitter)

    RT @RajivSarin5: Media Sensation on Rectal Cancers vanishing with Immuno drug Dostarlimab without Surgery/Radiatn/Chemo Its a signal getti…
    view full post

    June 9, 2022

    25

  • Valverde
    @Calpe19 (Twitter)

    RT @Shine_McShine: 2/ En primer lugar es de agradecer que, para variar, el periodista haya enlazado el artículo del que habla. Es este de a…
    view full post

    June 9, 2022

    27

  • xemaalcantara
    @xemaalcantara (Twitter)

    RT @Shine_McShine: 2/ En primer lugar es de agradecer que, para variar, el periodista haya enlazado el artículo del que habla. Es este de a…
    view full post

    June 9, 2022

    27

  • Jack Dancer(テイオー)
    @JackDancer55 (Twitter)

    @NazologyInfo リツイートは控えるけど...本当なら夢のような出来事だ！ といいつつNEJMでいそいそと原文をあたったりしているあたりもうね...w https://t.co/FnUjuNoFR2
    view full post

    June 9, 2022

  • diego alejandro
    @alejocastillo81 (Twitter)

    RT @Shine_McShine: 2/ En primer lugar es de agradecer que, para variar, el periodista haya enlazado el artículo del que habla. Es este de a…
    view full post

    June 9, 2022

    27

  • Shine McShine
    @Shine_McShine (Twitter)

    2/ En primer lugar es de agradecer que, para variar, el periodista haya enlazado el artículo del que habla. Es este de aquí, aunque or desgracia se encuentra tras un paywall y todavía no está en sci-hub: https://t.co/PClbwP8UXO
    view full post

    June 9, 2022

    425

    27

  • Rajiv Sarin MD
    @RajivSarin5 (Twitter)

    Media Sensation on Rectal Cancers vanishing with Immuno drug Dostarlimab without Surgery/Radiatn/Chemo Its a signal getting brighter but 1 among many wins of #CancerResearch that needs unlimited Public support & resources/ facilitation from Govt/Charities https://t.co/sz0DpWBC2v https://t.co/n53DDFJm6i
    view full post

    June 9, 2022

    81

    25

  • Dilara Sarı
    @genetik_muh (Twitter)

    Hastaların %20’si belli yan etkiler ile karşılaştı lakin bu yan etkiler kolayca yönetildi. Çalışma henüz küçük bir grup içinde yapıldığı için alınacak çok yol var. Tedavinin diğer kanser türlerinde etkili olup olmayacağı araştırılıyor
    view full post

    June 9, 2022

    19

    1

  • biodomtomi
    @biodomtomi (Twitter)

    RT @JAX_CKB: Exciting results show all 12 patients with MMR-deficient, locally advanced rectal cancer achieved a complete response to singl…
    view full post

    June 9, 2022

    7

  • antonio antonov
    @antoninianton (Twitter)

    RT @pona_igor: @iurevych_iurii @fantichok https://t.co/bC5pY4uYPu
    view full post

    June 9, 2022

    1

  • Rewatee Gokhale
    @wouldbscientist (Twitter)

    RT @JAX_CKB: Exciting results show all 12 patients with MMR-deficient, locally advanced rectal cancer achieved a complete response to singl…
    view full post

    June 8, 2022

    7

  • Sneha
    @thelifestylerea (Twitter)

    Cancer drug had 100% success rate The findings are reported in The New England Journal of Medicine.https://t.co/UJzZ5ovtGC #CancerResearch #cancer #US #medicalscience https://t.co/EJVJ0acxio
    view full post

    June 8, 2022

  • Черноока
    @chernyvaya (Twitter)

    @Slava__Ukraine_ @bichikota https://t.co/Bj2hnpx2l7
    view full post

    June 8, 2022

  • Sara Patterson
    @spatt79 (Twitter)

    RT @JAX_CKB: Exciting results show all 12 patients with MMR-deficient, locally advanced rectal cancer achieved a complete response to singl…
    view full post

    June 8, 2022

    7

  • bichik under fire
    @bichikota (Twitter)

    RT @chernyvaya: Першоджерело https://t.co/Bj2hnpx2l7
    view full post

    June 8, 2022

    1

  • Nizar Asadi نزار اسدي
    @nizarasadi (Twitter)

    Great hope for cancer patients… yet to see the long term and significant number of patients with the results… PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | NEJM great https://t.co/epN0C0kgg3
    view full post

    June 8, 2022

  • Черноока
    @chernyvaya (Twitter)

    Першоджерело https://t.co/Bj2hnpx2l7
    view full post

    June 8, 2022

    4

    1


  • @pona_igor (Twitter)

    @hunk62 @fantichok https://t.co/bC5pY4uYPu
    view full post

    June 8, 2022

    1


  • @pona_igor (Twitter)

    @iurevych_iurii @fantichok https://t.co/bC5pY4uYPu
    view full post

    June 8, 2022

    1

  • The Jackson Laboratory Cancer Center
    @JAXcancercenter (Twitter)

    RT @JAX_CKB: Exciting results show all 12 patients with MMR-deficient, locally advanced rectal cancer achieved a complete response to singl…
    view full post

    June 8, 2022

    7

  • Daniel Messiha, MD
    @realdocdan (Twitter)

    Huge day for #oncology! Phase II study @AndreaCercek et al. pub @NEJM: anti-PD1-monoclonal #antibody treatment w/ dostarlimab, results in
    view full post

    June 8, 2022

    2

    1

  • Ryan Russell
    @ryruss02 (Twitter)

    RT @JAX_CKB: Exciting results show all 12 patients with MMR-deficient, locally advanced rectal cancer achieved a complete response to singl…
    view full post

    June 8, 2022

    7

  • JAX Clinical Knowledgebase (JAX-CKB)
    @JAX_CKB (Twitter)

    Exciting results show all 12 patients with MMR-deficient, locally advanced rectal cancer achieved a complete response to single-agent PD-1 blockade recently presented at #ASCO22 and published in @NEJM! #PrecisionMedicine #immunotherapy https://t.co/gaW9vrcnTo
    view full post

    June 8, 2022

    9

    7

  • Hossein Allahdadi
    @hos_allahdadi (Twitter)

    https://t.co/c7FRTpRg0H
    view full post

    June 8, 2022

  • Kordasti_lab
    @KordastiL (Twitter)

    A complete response to PD-1 blockade in all 12 patients with locally advanced rectal cancer! no surgery or chemo is needed after several months. This is fantastic! https://t.co/lzPN5xh0BR
    view full post

    June 8, 2022

    26

    4

  • Friederike Schiller
    @FriederikeSchi4 (Twitter)

    RT @SheepNoMore7: In einer neuen vielversprechenden Krebsstudie wurden 12 von 12 Patienten erfolgreich geheilt. https://t.co/Va06tccSOb
    view full post

    June 8, 2022

    1

  • Victor Goossens, 1 Investor
    @1Investeerder (Twitter)

    Dostarlimab, een imuuntherapie van Glaxo [GSK] tegen Endeldarm kanker heeft een 100% succes ratio. Zeker de moeite waard om dit middel in de gaten te houden voor andere vormen van kanker https://t.co/Xj9D1JnRhA https://t.co/k5Kgs2Gqnc
    view full post

    June 8, 2022

  • Wahrsager
    @SheepNoMore7 (Twitter)

    In einer neuen vielversprechenden Krebsstudie wurden 12 von 12 Patienten erfolgreich geheilt. https://t.co/Va06tccSOb
    view full post

    June 8, 2022

    1

    1

  • Weg des Feuervogels
    @WegFeuer (Twitter)

    In einer neuen vielversprechenden Krebsstudie wurden 12 von 12 Patienten erfolgreich geheilt. https://t.co/Va06tccSOb
    view full post

    June 8, 2022

    1

    1

  • Antibodies.com
    @Antibodies_com (Twitter)

    Fascinating new article in NEJM [PMID: 35660797]; reporting that all 12 patients in a Phase 2 study investigating dostarlimab for rectal adenocarcinoma had a clinical complete response - with no evidence of tumour detected! https://t.co/Cd4RjvqFEq #cancer #research #lifescience https://t.co/oyhVyBBkOH
    view full post

    June 8, 2022

  • Fradi Frad Dreizehn
    @frad_fradi (Twitter)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer https://t.co/CHj8KbYjlR
    view full post

    June 8, 2022

  • Pradeep Keshavanarayana
    @bkprdp (Twitter)

    Wow! This is big. If this is scalable, its a great news for the society, and all the cancer researchers. PD-1 Blockade in Mismatch Repair-Deficient, Locally Advanced Rectal Cancer https://t.co/uEseZwUKUB
    view full post

    June 8, 2022

  • Dr L Boominathan PhD
    @DrLBoominathan (Twitter)

    This interesting study published in NEJM suggests that blocking PD-1, using dostarlimab, can cure mismatch Repair-Deficient, Locally Advanced Rectal Cancer. https://t.co/nhcORFnMGM ->Insights into cancer: https://t.co/DL81Ei67OH https://t.co/y5n4G5FKGC https://t.co/Htpbwo6ZES https://t.co/gHP7xzXqWg
    view full post

    June 8, 2022

  • ✨
    @ukht__ (Twitter)

    This is incredible SubhanaAllah https://t.co/6JEmTcGhMn
    view full post

    June 8, 2022

  • Camila Ramírez
    @camilaramirezav (Twitter)

    RT @AndreaBranda8: Hito científico: cáncer de colon eliminado! https://t.co/ieMJlmIuaL
    view full post

    June 7, 2022

    2

  • DR LI Health
    @latirina (Twitter)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer | NEJM https://t.co/9PjmaK7Xbn
    view full post

    June 7, 2022

  • MD_PhD in Japan
    @japan_phd (Twitter)

    ミスマッチ修復欠損進行肛門癌にチェックポイント阻害剤が著効⁉️ 12例中12例でfull response. 治療開始から１年で化学放射線療法は0例で使用。 PD-1 Blockade in Mismatch Repair-Deficient, Locally Advanced Rectal Cancer - PubMed https://t.co/d1W9S0KLgA
    view full post

    June 7, 2022

    1

  • bigman
    @MoeBIO375 (Twitter)

    @Jayson_Parker https://t.co/7uBsQgZ9QD
    view full post

    June 7, 2022

    1

  • Gustavo Agosto
    @gustavoagosto77 (Twitter)

    RT @AndreaBranda8: Hito científico: cáncer de colon eliminado! https://t.co/ieMJlmIuaL
    view full post

    June 7, 2022

    2

  • Andrea Branda-Sica
    @AndreaBranda8 (Twitter)

    Hito científico: cáncer de colon eliminado! https://t.co/ieMJlmIuaL
    view full post

    June 7, 2022

    5

    2

  • Apolwlos
    @apolwlos (Twitter)

    Πολύ καλά νέα αυτά https://t.co/Sa7rEWBot8
    view full post

    June 7, 2022

    1

  • Meded
    @cryptovitas (Twitter)

    RT @dr_bhushannk: Unheard of - Complete Remission of rectal cancer in every single patient in small drug trial. What an amazing scientific…
    view full post

    June 7, 2022

    1

  • Bhushan
    @dr_bhushannk (Twitter)

    Unheard of - Complete Remission of rectal cancer in every single patient in small drug trial. What an amazing scientific achievement! #dostarlimab #scientists #MedTwitter #CancerResearch #clinicaltrials https://t.co/1kQT4ih6U3 https://t.co/4PCu3gJmYz
    view full post

    June 7, 2022

    2

    1

  • Ian George Chambers, Ph.D.
    @IGC_Science (Twitter)

    Awesome! https://t.co/F3mRakpmSb
    view full post

    June 7, 2022

  • Roger Blackwell
    @rogerablackwell (Twitter)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer https://t.co/ZqRdcbOnu4
    view full post

    June 7, 2022

  • أحـمـد الـطـيـار |
    @Ahmad_ALtayyar7 (Twitter)

    الي يبغى يستزيد ويقرأ بعض التفاصيل هنا رابط الدراسة ورابط آخر يتكلم عن الدراسة • https://t.co/vgguiddsDe • https://t.co/cSafgnXVC3
    view full post

    June 7, 2022

    4

  • Manuel Gonzalez Bermudez
    @mgonber1 (Twitter)

    ¿Abrirá la inmunoterapia más caminos hacia la preservación de órgano en cáncer rectal? La respuesta parece evidente. https://t.co/GcVY1vYVhW
    view full post

    June 7, 2022

  • Pierre Gholam MD
    @livermd.bsky.social (Bluesky)

    PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer #conquercancer https://www.nejm.org/doi/full/10.1056/NEJMoa2201445
    view full post

    June 6, 2022

Abstract Synopsis

  • Neoadjuvant chemotherapy and radiation are standard treatments for locally advanced rectal cancer, particularly in cases with mismatch repair deficiency, which may respond well to PD-1 blockade therapy.
  • A phase 2 study was conducted using dostarlimab, an anti-PD-1 monoclonal antibody, to treat patients before typical chemoradiotherapy and surgery, with potential for some patients to skip the latter if they showed a complete response.
  • All 12 patients treated in the study displayed a clinical complete response with no tumor detected and no reported adverse effects of significant severity, indicating promising results for this approach.