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The discussions reflect a strong consensus on the significance of the research, with comments praising the paper’s thoughtful design and clinical implications, such as highlighting how the ACKR1 CC genotype affects drug discontinuation rates independent of race; words like 'fantastic,' 'thoughtfully conceived,' and 'significant' demonstrate enthusiasm and recognition of real-world impact, indicating both high engagement and impact.
Most discussions emphasize the importance and validity of the findings, especially regarding the genetic basis of drug response, indicating strong agreement.
The posts demonstrate high interest by referencing specific genetic variants and emphasizing the clinical significance of the research.
Many comments delve into the implications for clinical practice and pharmacogenomics, showing deep engagement with the topic.
The discussions highlight the potential for personalized medicine and addressing healthcare disparities, signifying a high impact.
A wake-up call for drug-gene interactions https://t.co/CufZhaKPp9 by @CeciliaChung11 and colleagues @VUMChealth @VUMC_Medicine @VUMCClinPharm https://t.co/Cm6nK5Ji0X @AnnalsofIM https://t.co/3TV4Ztl2Iz
Congratulations to Alyson Dickson and @CeciliaChung11 of @VUMC_Medicine (@VUMCClinPharm ) on their fantastic paper highlighting a pharmacogenomic health care inequity due to the ACKR1 CC genotype (@AnnalsofIM). Beautiful and important work. https://t.co/t9UPMkyYnX
Study shows genotype leads to discontinued, decreased medication @AnnalsofIM https://t.co/fJAxaKgIPu https://t.co/8To4QocbXZ
Had fun joining @CeciliaChung11 talking about awesome her paper (https://t.co/RXUPKIPf8O) on leukopenia, azathioprine and the ACKR1 benign neutropenia phenotype. https://t.co/XUIm8DDTxW
I am very intrigue by these figures showing how important are race and genotype in pharmacogenomics research! Thank you for sharing this #pgxread! https://t.co/NRH10aoEFL https://t.co/oAuHjNjal2 https://t.co/F70hY641MX
Must-read article on impact of Duffy null on clinical care! Highlighting the need to look at this in cancer care as well. @ACPinternists @DanaFarber @BrighamHeme Race, Genotype, and Azathioprine Discontinuation: A Cohort Study: https://t.co/IQYX1VKYdw
Nancy Cox examines how genetics can help unravel institutionalized health inequity, focusing on the implications for African American patients. This video discusses related research on the association between genotype…
@jeffsparks @BrighamWomens @JAMA_current Yes, they were excluded in our cohort. However, this amazing paper shows that azathioprine discontinuation was much higher for Duffy null patients with no difference between Black and White Duffy non-null. Much work to be done! https://t.co/t4aeSv9O9w
RT @SashaGusevPosts: @Eric_Fauman Good recent talk on this from @NancyGenetics (https://t.co/XWuD6MGSA8) using WBC and unnecessary biopsies…
@Eric_Fauman Good recent talk on this from @NancyGenetics (https://t.co/XWuD6MGSA8) using WBC and unnecessary biopsies as an example (https://t.co/l5m50Lz9qC).
Had fun joining @CeciliaChung11 talking about awesome her paper (https://t.co/RXUPKIPf8O) on leukopenia, azathioprine and the ACKR1 benign neutropenia phenotype. https://t.co/XUIm8DDTxW
Race, Genotype, and Azathioprine Discontinuation: A Cohort Study: Annals of Internal Medicine: Vol 175, No 8 https://t.co/qMirT5fKEr
Another example: @CeciliaChung11 and Alyson Dickson showed that the ACKR1 rs2814778 variant accounted for a #RacialDisparity in discontinuation rates due to low white blood cell counts for the drug Azathioprine. https://t.co/t9UPMkQzMx
RT @scottmwilliams9: Beyond Race: A Wake-up Call for Drug Therapy Informed by Genotyping | Annals of Internal Medicine https://t.co/YhuQFtG…
Beyond Race: A Wake-up Call for Drug Therapy Informed by Genotyping | Annals of Internal Medicine https://t.co/YhuQFtGAkT A nice discussion of race and genetics in light of new paper https://t.co/kL95YR7yPk on adverse drug responses
RT @medical_xpress: Study shows genotype leads to discontinued, decreased medication @AnnalsofIM https://t.co/fJAxaKgIPu https://t.co/8To4Q…
Race, Genotype, and Azathioprine Discontinuation https://t.co/56hA669A1i
Race, Genotype, and Azathioprine Discontinuation https://t.co/SpuzZNv6iX
Race, Genotype, and Azathioprine Discontinuation https://t.co/AbNDNQS6dC
Race, Genotype, and Azathioprine Discontinuation https://t.co/FRTvpW9Vkn
#ICYMI from @VUMChealth @CeciliaChung11: patients with CC genotype at 3x higher risk for #azathioprine discontinuation attributed to hematopoietic toxicity and lower thiopurine doses, even after adjusting for race: https://t.co/ERRagjAM0H https://t.co/FI8sLbt0Ne
This is a great paper, thoughtfully conceived and with significant clinical implications for thiopurine dosing. Race, Genotype, and Azathioprine Discontinuation: A Cohort Study https://t.co/BC6CQhR9MB
RT @JDMosley_Moses: Congratulations to Alyson Dickson and @CeciliaChung11 of @VUMC_Medicine (@VUMCClinPharm ) on their fantastic paper high…
RT @EricTopol: A wake-up call for drug-gene interactions https://t.co/CufZhaKPp9 by @CeciliaChung11 and colleagues @VUMChealth @VUMC_Medici…
RT @pgrnhub: I am very intrigue by these figures showing how important are race and genotype in pharmacogenomics research! Thank you for sh…
Race, Genotype, and Azathioprine Discontinuation: A Cohort Study: Annals of Internal Medicine: Vol 0, No 0 https://t.co/iAWQN1XlQj
I am very intrigue by these figures showing how important are race and genotype in pharmacogenomics research! Thank you for sharing this #pgxread! https://t.co/NRH10aoEFL https://t.co/oAuHjNjal2 https://t.co/F70hY641MX
RT @EricTopol: A wake-up call for drug-gene interactions https://t.co/CufZhaKPp9 by @CeciliaChung11 and colleagues @VUMChealth @VUMC_Medici…
RT @EricTopol: A wake-up call for drug-gene interactions https://t.co/CufZhaKPp9 by @CeciliaChung11 and colleagues @VUMChealth @VUMC_Medici…
RT @EricTopol: A wake-up call for drug-gene interactions https://t.co/CufZhaKPp9 by @CeciliaChung11 and colleagues @VUMChealth @VUMC_Medici…
RT @EricTopol: A wake-up call for drug-gene interactions https://t.co/CufZhaKPp9 by @CeciliaChung11 and colleagues @VUMChealth @VUMC_Medici…
RT @EricTopol: A wake-up call for drug-gene interactions https://t.co/CufZhaKPp9 by @CeciliaChung11 and colleagues @VUMChealth @VUMC_Medici…
RT @EricTopol: A wake-up call for drug-gene interactions https://t.co/CufZhaKPp9 by @CeciliaChung11 and colleagues @VUMChealth @VUMC_Medici…
RT @EricTopol: A wake-up call for drug-gene interactions https://t.co/CufZhaKPp9 by @CeciliaChung11 and colleagues @VUMChealth @VUMC_Medici…
RT @EricTopol: A wake-up call for drug-gene interactions https://t.co/CufZhaKPp9 by @CeciliaChung11 and colleagues @VUMChealth @VUMC_Medici…
RT @EricTopol: A wake-up call for drug-gene interactions https://t.co/CufZhaKPp9 by @CeciliaChung11 and colleagues @VUMChealth @VUMC_Medici…
RT @EricTopol: A wake-up call for drug-gene interactions https://t.co/CufZhaKPp9 by @CeciliaChung11 and colleagues @VUMChealth @VUMC_Medici…
RT @EricTopol: A wake-up call for drug-gene interactions https://t.co/CufZhaKPp9 by @CeciliaChung11 and colleagues @VUMChealth @VUMC_Medici…
RT @EricTopol: A wake-up call for drug-gene interactions https://t.co/CufZhaKPp9 by @CeciliaChung11 and colleagues @VUMChealth @VUMC_Medici…
RT @EricTopol: A wake-up call for drug-gene interactions https://t.co/CufZhaKPp9 by @CeciliaChung11 and colleagues @VUMChealth @VUMC_Medici…
RT @EricTopol: A wake-up call for drug-gene interactions https://t.co/CufZhaKPp9 by @CeciliaChung11 and colleagues @VUMChealth @VUMC_Medici…
https://t.co/8xZrLd44XH
RT @EricTopol: A wake-up call for drug-gene interactions https://t.co/CufZhaKPp9 by @CeciliaChung11 and colleagues @VUMChealth @VUMC_Medici…
RT @EricTopol: A wake-up call for drug-gene interactions https://t.co/CufZhaKPp9 by @CeciliaChung11 and colleagues @VUMChealth @VUMC_Medici…
RT @EricTopol: A wake-up call for drug-gene interactions https://t.co/CufZhaKPp9 by @CeciliaChung11 and colleagues @VUMChealth @VUMC_Medici…
RT @EricTopol: A wake-up call for drug-gene interactions https://t.co/CufZhaKPp9 by @CeciliaChung11 and colleagues @VUMChealth @VUMC_Medici…
RT @EricTopol: A wake-up call for drug-gene interactions https://t.co/CufZhaKPp9 by @CeciliaChung11 and colleagues @VUMChealth @VUMC_Medici…
RT @EricTopol: A wake-up call for drug-gene interactions https://t.co/CufZhaKPp9 by @CeciliaChung11 and colleagues @VUMChealth @VUMC_Medici…
RT @EricTopol: A wake-up call for drug-gene interactions https://t.co/CufZhaKPp9 by @CeciliaChung11 and colleagues @VUMChealth @VUMC_Medici…
RT @EricTopol: A wake-up call for drug-gene interactions https://t.co/CufZhaKPp9 by @CeciliaChung11 and colleagues @VUMChealth @VUMC_Medici…
RT @EricTopol: A wake-up call for drug-gene interactions https://t.co/CufZhaKPp9 by @CeciliaChung11 and colleagues @VUMChealth @VUMC_Medici…
RT @EricTopol: A wake-up call for drug-gene interactions https://t.co/CufZhaKPp9 by @CeciliaChung11 and colleagues @VUMChealth @VUMC_Medici…
RT @EricTopol: A wake-up call for drug-gene interactions https://t.co/CufZhaKPp9 by @CeciliaChung11 and colleagues @VUMChealth @VUMC_Medici…
A wake-up call for drug-gene interactions https://t.co/CufZhaKPp9 by @CeciliaChung11 and colleagues @VUMChealth @VUMC_Medicine @VUMCClinPharm https://t.co/Cm6nK5Ji0X @AnnalsofIM https://t.co/3TV4Ztl2Iz
New from @VUMChealth @CeciliaChung11: patients with CC genotype at 3x higher risk for #azathioprine discontinuation attributed to hematopoietic toxicity and lower thiopurine doses, even after adjusting for race: https://t.co/2IfAczkT30 https://t.co/kAsIlDXjFy
RT @medical_xpress: Study shows genotype leads to discontinued, decreased medication @AnnalsofIM https://t.co/fJAxaKgIPu https://t.co/8To4Q…
RT @medical_xpress: Study shows genotype leads to discontinued, decreased medication @AnnalsofIM https://t.co/fJAxaKgIPu https://t.co/8To4Q…
RT @medical_xpress: Study shows genotype leads to discontinued, decreased medication @AnnalsofIM https://t.co/fJAxaKgIPu https://t.co/8To4Q…
Must-read article on impact of Duffy null on clinical care! Highlighting the need to look at this in cancer care as well. @ACPinternists @DanaFarber @BrighamHeme Race, Genotype, and Azathioprine Discontinuation: A Cohort Study: https://t.co/IQYX1VKYdw
RT @medical_xpress: Study shows genotype leads to discontinued, decreased medication @AnnalsofIM https://t.co/fJAxaKgIPu https://t.co/8To4Q…
RT @medical_xpress: Study shows genotype leads to discontinued, decreased medication @AnnalsofIM https://t.co/fJAxaKgIPu https://t.co/8To4Q…
RT @medical_xpress: Study shows genotype leads to discontinued, decreased medication @AnnalsofIM https://t.co/fJAxaKgIPu https://t.co/8To4Q…
RT @medical_xpress: Study shows genotype leads to discontinued, decreased medication @AnnalsofIM https://t.co/fJAxaKgIPu https://t.co/8To4Q…
RT @medical_xpress: Study shows genotype leads to discontinued, decreased medication @AnnalsofIM https://t.co/fJAxaKgIPu https://t.co/8To4Q…
Study shows genotype leads to discontinued, decreased medication @AnnalsofIM https://t.co/fJAxaKgIPu https://t.co/8To4QocbXZ
Congratulations to Alyson Dickson and @CeciliaChung11 of @VUMC_Medicine (@VUMCClinPharm ) on their fantastic paper highlighting a pharmacogenomic health care inequity due to the ACKR1 CC genotype (@AnnalsofIM). Beautiful and important work. https://t.co/t9UPMkyYnX