Concepts of Entheseal Pain.

Enrico De Lorenzis, Gerlando Natalello, David Simon, Georg Schett, Maria Antonietta D'Agostino

April 2023 Arthritis Rheumatol

Synopsis of Social media discussions

The discussions express strong support for the publication, with phrases like 'must consider' and 'game changer' indicating high interest. Several posters mention key concepts such as 'neurovascular invasion' and its role in pain, using technical terms that suggest a deep engagement with the material and its implications for understanding entheseal conditions.

A
Agreement
 Moderate agreement

Most discussions acknowledge the importance of the publication and support its findings on entheseal pain, reflecting general consensus.

I
Interest
 High level of interest

The discussions demonstrate high interest, with enthusiasm expressed about the review article and its relevance to understanding disease mechanisms.

E
Engagement
 Moderate level of engagement

Participants show moderate engagement, referencing mechanisms like 'neurovascular invasion' and discussing the implications of the research for disease understanding.

I
Impact
 Moderate level of impact

While the discussions highlight the significance of the publication, they mostly serve to generate awareness rather than drive immediate change or applications.

Social Mentions

YouTube

2 Videos

Facebook

11 Posts

Twitter

3 Posts

News

5 Articles

Metrics

Video Views

24

Total Likes

15

Extended Reach

17,764

Social Features

21

Timeline: Posts about article

Top Social Media Posts

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    nr-axSpAと機能性疾患の狭間のtwitterでの議論が大変勉強になりました． 少し話ズレますが付着部炎も似た問題があって，炎症があって引いても“neurovascular invasion”が起きて画像所見上異常がないのに疼痛が残ってるパターンになり得たり本当にカオス． https://t.co/8VHkr9FIKZ
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Abstract Synopsis

  • Entheseal pain is a primary symptom in related diseases, caused by inflammation and mechanical stress, even though the enthesis itself has few nerve endings.
  • During inflammation, chemicals like eicosanoids, cytokines, and neuropeptides promote nerve and blood vessel growth into the enthesis, and activate nearby nerve cells, leading to pain.
  • This nerve and vessel invasion can cause pain that doesn't always match what is seen on imaging scans, explaining why symptoms and structural findings often don't align in entheseal conditions.]