J Intern Med December 2022 PMID 35819136

Antibiotics and mental health: The good, the bad and the ugly.

Katherine Dinan, Timothy Dinan

Mentions

100
Peak: 51 in Nov 2022
across 5 sources since Jul 2022

Extended reach

626,226
potential audience

Total likes

23,194

Video views

334,158

Mentions per month

Jul 2022 – Apr 2025

Where it's discussed

  • X / Twitter89 posts
  • News5 articles
  • Facebook4 posts
  • Bluesky1 posts
  • YouTube1 videos

AI synopsis

What people are saying

Several posts highlight specific points from the article, like the significant decrease in gut microbial diversity as a risk factor for depression and the need for public awareness campaigns about antibiotic-related mental health issues. Phrases like 'antibiotics drive anxiety and depression' and references to scientific evidence strongly indicate that people are not only concerned but are also looking for actionable insights, underscoring the serious tone and urgency around the topic.

AgreementModerate agreement

The majority of discussions support the findings, particularly regarding the risks of antibiotics leading to depression and anxiety.

InterestHigh interest

There is a high level of curiosity reflected in the posts, indicating that many participants are eager to learn more about the implications of the article.

EngagementModerate engagement

While some discussions are informative, there are instances of deeper engagement, especially when users delved into the mechanisms behind antibiotics' effects on mental health.

ImpactHigh impact

Many contributors perceive that the findings could have substantial implications for public health awareness and antibiotic use.

Abstract in brief

  • Antibiotics can cause psychiatric side effects, particularly depression and anxiety, due to their impact on the brain-gut microbiota axis.
  • Some antibiotics, like isoniazid and minocycline, have shown potential antidepressant effects, highlighting that not all antibiotic actions are harmful.
  • The alteration of gut microbiota diversity and other mechanisms influenced by antibiotics may increase the risk of mental health issues; thus, clinicians should be aware of these potential side effects.

Top posts

Most liked on X and Bluesky
IberianCitizen
@IberianCitizen · X

Antibióticos y salud mental

Nov 29, 2022 · 149 likes · 59 shares · 12,931 followers View post →
GutMicrobiota Health
@GMFHx · X

Antimicrobial resistance is a public health threat. Efforts should be made to reduce off-target brain–gut–microbiota effects resulting in mental health problems, argue Katherine Dinan and @TedDinan https://t.co/ZZ504lUuce https://t.co/1pCFcpfTEQ

Dec 12, 2022 · 50 likes · 8 shares · 35,521 followers View post →
Kristie Leong M.D.
@DrKristieLeong · X

Aug 14, 2024 · 43 likes · 6 shares · 59,613 followers View post →
The GUT CLUB
@club_gut · X

@HealthyFellow @_atanas_ @_INPST @ScienceCommuni2 @DHPSP @Muzzpol @ktguzz @ForgeRat @DrRuscio @DrDeborahMD @HeidiHmoretti @ralzahrani2020 @ToshiyukiHorie @BrianLenzkes July 2022 Review: Antibiotics are also linked to increased risk of mental illness. "Antibiotics and mental health: The good, the bad and the ugly" https://t.co/ZngeGjd42I @TedDinan https://t.co/LzuqgdaTOp

Jan 14, 2023 · 7 likes · 6 shares · 2,322 followers View post →
Agnieszka Szuster-Ciesielska
@AgnieszkaSzust3 · X

37/ Piśmiennictwo: 1. https://t.co/XfFoIosewf 2. https://t.co/opLmJQ1FYj 3. https://t.co/9erv7pVoZJ 4. https://t.co/IhkHJx03dE 5. https://t.co/kDh4X1Sc83 6. https://t.co/KYO0ZOohRm 7. https://t.co/IPA5O7I73s

Aug 15, 2023 · 5 likes · 8,507 followers View post →
Armando Ribeiro
@Armando_Ribeiro · X

Antibiotics and #mentalhealth: The good, the bad and the ugly https://t.co/BgzbwEvp3N

Nov 29, 2022 · 1 like · 5,048 followers View post →

All mentions

The GUT CLUB
@club_gut · X

RT @club_gut: @HealthyFellow @_atanas_ @_INPST @ScienceCommuni2 @DHPSP @Muzzpol @ktguzz @ForgeRat @DrRuscio @DrDeborahMD @HeidiHmoretti @ra…

Apr 21, 2025 · 6 shares · 2,322 followers View post →
Szyzygy
@Szyzygy2 · X

RT @club_gut: @HealthyFellow @_atanas_ @_INPST @ScienceCommuni2 @DHPSP @Muzzpol @ktguzz @ForgeRat @DrRuscio @DrDeborahMD @HeidiHmoretti @ra…

Nov 26, 2024 · 6 shares · 1,179 followers View post →
The GUT CLUB
@club_gut · X

RT @club_gut: @HealthyFellow @_atanas_ @_INPST @ScienceCommuni2 @DHPSP @Muzzpol @ktguzz @ForgeRat @DrRuscio @DrDeborahMD @HeidiHmoretti @ra…

Nov 24, 2024 · 6 shares · 2,322 followers View post →
Divinity Seven♻️
@SevenDivinity · X

RT @DrKristieLeong:

Aug 14, 2024 · 6 shares · 1,428 followers View post →
EBRAH SSALI - PhD (Candidate)
@IBRAHSSALI1 · X

RT @DrKristieLeong:

Aug 14, 2024 · 6 shares · 799 followers View post →
Kristie Leong M.D.
@DrKristieLeong · X

Aug 14, 2024 · 43 likes · 6 shares · 59,613 followers View post →
Alysha Keys
@alyshner · X

Some antibiotics bring about a significant decrease in gut microbial diversity, and this is viewed as a risk factor for depression. Overall, antibiotics increase the prevalence of both depression and anxiety. https://t.co/YG73BkeG7K

Jul 17, 2024 · 1,437 followers View post →
$hompz
@shompzilla · X

@MarcLobliner https://t.co/RZmIYBJ9rA

Jun 8, 2024 · 1 like · 2,175 followers View post →
Reema Felemban
@Reemagf · X

اذا كنت تشعر بتغير في المزاج مع كورس المضاد الحيوي أنت لست وحيداً

May 28, 2024 · 378 followers View post →
Agnieszka Szuster-Ciesielska
@AgnieszkaSzust3 · X

37/ Piśmiennictwo: 1. https://t.co/XfFoIosewf 2. https://t.co/opLmJQ1FYj 3. https://t.co/9erv7pVoZJ 4. https://t.co/IhkHJx03dE 5. https://t.co/kDh4X1Sc83 6. https://t.co/KYO0ZOohRm 7. https://t.co/IPA5O7I73s

Aug 15, 2023 · 5 likes · 8,507 followers View post →
Nicholas (@ultimape) Perry
@ultimape.bsky.wovensoup.com · Bluesky

I hope one day we'll have public awareness anti-drug campaigns talking about how antibiotics drive anxiety and depression. https://pubmed.ncbi.nlm.nih.gov/35819136/ And you think cannabis associated mental health issues is bad, check out the rates of SSRI induced psychosis.

Aug 10, 2023 · 1 share View post →
Perry Williams, MS, DC, DACBSP, USAW
@Pwilldc · X

https://t.co/P17Eockve4. Here is another one.

Jul 28, 2023 · 1,066 followers View post →
Aine
@amobeirne · X

RT @amobeirne: 4) "Antibiotics and mental health: The good, the bad and the ugly" https://t.co/wGqn9F30s6

Jul 14, 2023 · 1 share · 3,047 followers View post →
Ezra
@postie_16 · X

@leRhanalt Here’s an article on the effects of antibiotics on the stomach if you’re curious as to why they can make people feel depressed, probiotics can help restore the gut micro biome and mitigate some of the effects! https://t.co/lyoWaUlCWM

Jun 10, 2023 · 1 like · 13 followers View post →
Aine
@amobeirne · X

4) "Antibiotics and mental health: The good, the bad and the ugly" https://t.co/wGqn9F30s6

Apr 22, 2023 · 1 like · 1 share · 3,047 followers View post →
Scary Times
@Ferng6Ferng · X

@newschambers https://t.co/H7e73AuyIN

Apr 21, 2023 · 1 like · 3,740 followers View post →
Scary Times
@Ferng6Ferng · X

@SlattsSean https://t.co/H7e73AuyIN citation for specific article but really just google antibiotics & depression & you'll see numerous citations evidencing depression is an unequivocal risk factor with antibiotic use. Which is why they should be used sparingly.

Apr 21, 2023 · 1 like · 3,740 followers View post →
Dan Breen
@DanBree1992 · X

@newschambers Here's some recent research saying there may be a link between antibiotics and depression. https://t.co/i1J4KpukQo https://t.co/to0kAEXR84

Apr 21, 2023 · 87 followers View post →
EM
@McEndeus · X

There is medical evidence backing up the point that was being made: https://t.co/7Aqg7ssW8Y "Antibiotics are recognised as, on occasion, producing psychiatric side effects, most notably depression and anxiety”

Apr 21, 2023 · 187 followers View post →
Tomaso Antonacci
@TomasoAntonacci · X

@chydorina @jmatwood @remissionbiome @h_sokol https://t.co/7LVL32thsh this paper is really interesting -they clearly state the principles of the issue of antibiotics / alteration of the barrier & the impacted gut brain axis cascade / neuro-inflammation, they also treat the question of minocycline & microglia, a tetracycline

Feb 2, 2023 · 2,387 followers View post →
TheHealthyRD
@HeidiHmoretti · X

RT @club_gut: @HealthyFellow @_atanas_ @_INPST @ScienceCommuni2 @DHPSP @Muzzpol @ktguzz @ForgeRat @DrRuscio @DrDeborahMD @HeidiHmoretti @ra…

Jan 15, 2023 · 6 shares · 74,967 followers View post →
Muzzpol
@Muzzpol · X

RT @club_gut: @HealthyFellow @_atanas_ @_INPST @ScienceCommuni2 @DHPSP @Muzzpol @ktguzz @ForgeRat @DrRuscio @DrDeborahMD @HeidiHmoretti @ra…

Jan 14, 2023 · 6 shares · 861 followers View post →
The GUT CLUB
@club_gut · X

RT @club_gut: @HealthyFellow @_atanas_ @_INPST @ScienceCommuni2 @DHPSP @Muzzpol @ktguzz @ForgeRat @DrRuscio @DrDeborahMD @HeidiHmoretti @ra…

Jan 14, 2023 · 6 shares · 2,322 followers View post →
The GUT CLUB
@club_gut · X

@HealthyFellow @_atanas_ @_INPST @ScienceCommuni2 @DHPSP @Muzzpol @ktguzz @ForgeRat @DrRuscio @DrDeborahMD @HeidiHmoretti @ralzahrani2020 @ToshiyukiHorie @BrianLenzkes July 2022 Review: Antibiotics are also linked to increased risk of mental illness. "Antibiotics and mental health: The good, the bad and the ugly" https://t.co/ZngeGjd42I @TedDinan https://t.co/LzuqgdaTOp

Jan 14, 2023 · 7 likes · 6 shares · 2,322 followers View post →
Dr Vikram Sakaleshpur Kumar
@vikkypaedia · X

Source: https://t.co/5kk3rfpqq1

Dec 27, 2022 · 1,287 followers View post →
Lisa Vlad
@LisaVlad2 · X

RT @GMFHx: Antimicrobial resistance is a public health threat. Efforts should be made to reduce off-target brain–gut–microbiota effects res…

Dec 12, 2022 · 8 shares · 104 followers View post →
Dr. Suzana Mantovani
@Tweet_Nutrition · X

RT @GMFHx: Antimicrobial resistance is a public health threat. Efforts should be made to reduce off-target brain–gut–microbiota effects res…

Dec 12, 2022 · 8 shares · 4,580 followers View post →
Armando Ribeiro
@Armando_Ribeiro · X

RT @GMFHx: Antimicrobial resistance is a public health threat. Efforts should be made to reduce off-target brain–gut–microbiota effects res…

Dec 12, 2022 · 8 shares · 5,048 followers View post →
Felipe Morillo
@morillo_fe · X

RT @GMFHx: Antimicrobial resistance is a public health threat. Efforts should be made to reduce off-target brain–gut–microbiota effects res…

Dec 12, 2022 · 8 shares · 748 followers View post →
Benjamin Gold
@BenjamminGold · X

RT @GMFHx: Antimicrobial resistance is a public health threat. Efforts should be made to reduce off-target brain–gut–microbiota effects res…

Dec 12, 2022 · 8 shares · 2,072 followers View post →
Alastair Kay
@AlastairK · X

RT @GMFHx: Antimicrobial resistance is a public health threat. Efforts should be made to reduce off-target brain–gut–microbiota effects res…

Dec 12, 2022 · 8 shares · 284 followers View post →
Jakub Hurych
@Jakub_Hurych · X

RT @GMFHx: Antimicrobial resistance is a public health threat. Efforts should be made to reduce off-target brain–gut–microbiota effects res…

Dec 12, 2022 · 8 shares · 89 followers View post →
GutMicrobiota Health
@GMFHx · X

Antimicrobial resistance is a public health threat. Efforts should be made to reduce off-target brain–gut–microbiota effects resulting in mental health problems, argue Katherine Dinan and @TedDinan https://t.co/ZZ504lUuce https://t.co/1pCFcpfTEQ

Dec 12, 2022 · 50 likes · 8 shares · 35,521 followers View post →
Carlos Saritama
@ama_carlos10 · X

Antibiotics and mental health: The good, the bad and the ugly https://t.co/CTrfAr8Bo8

Dec 12, 2022 · 264 followers View post →
Gilbrany Medina
@GilbranyMedinaS · X

RT @IberianCitizen: Antibióticos y salud mental

Dec 4, 2022 · 59 shares · 274 followers View post →
francisco Kaballero
@kabbayero · X

RT @IberianCitizen: Antibióticos y salud mental

Dec 1, 2022 · 59 shares · 60 followers View post →
Malkovich
@amvslp · X

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Nov 30, 2022 · 59 shares · 551 followers View post →
Sebas Barrionuevo
@sebasbarrio · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 30, 2022 · 59 shares · 116 followers View post →
Pienso, luego existo
@abelMinjarez · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 30, 2022 · 59 shares · 476 followers View post →
P de Puchito
@mrruccilove · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 30, 2022 · 59 shares · 203 followers View post →
Nutr. Victor Jauregui
@VictorNutr95 · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 30, 2022 · 59 shares · 49 followers View post →
Marcia Vítores
@marvit60 · X

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Nov 30, 2022 · 59 shares · 483 followers View post →
Cristina L
@dracrislopez · X

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Nov 30, 2022 · 59 shares · 899 followers View post →
Dra Carolina Castellanos
@Ccastell6 · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 30, 2022 · 59 shares · 92 followers View post →
TBH
@TBH_Healthcare · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 30, 2022 · 59 shares · 159 followers View post →
Manuel NR.
@ManuelNR2 · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 30, 2022 · 59 shares · 258 followers View post →
Gio
@Gio79750721 · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 30, 2022 · 59 shares · 564 followers View post →
Elia Ma. Perera B.
@eemmppbb · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 30, 2022 · 59 shares · 99 followers View post →
Dani Krebs
@pizahunter · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 30, 2022 · 59 shares · 1,677 followers View post →
Anita
@MarioPerit · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 30, 2022 · 59 shares · 65 followers View post →
Dr. Angelo Martinez Urb.
@DrAmartinezur93 · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 30, 2022 · 59 shares · 516 followers View post →
Ruben Aponte
@Aponte8Ruben · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 28 followers View post →
JosMigAst
@JoseMiguelAsto1 · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 49 followers View post →
Shago
@chago82 · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 121 followers View post →
Asakura Koyomi
@Adeskarg · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 64 followers View post →
Metzery
@metzeryvegazamo · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 107 followers View post →
Miu miu
@JennifferBC · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 726 followers View post →
DigitalYeda
@UMDBrianPajares · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 446 followers View post →
Cecilia Kitta
@CeciliaKitta · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 13 followers View post →
Dra. Angélica García
@lica2284 · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 372 followers View post →
Dra.5vid / PRN
@raquelpeva · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 244 followers View post →
Raví
@lhbr33 · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 122 followers View post →
jenny Rodriguez
@jennyRo17529367 · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 360 followers View post →
Mary Medina
@marylmedina · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 971 followers View post →
Dra. Leon
@RossDra · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 67 followers View post →
Glad ♛
@GladHMO · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 45 followers View post →
Di Isor
@dioraluna · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 202 followers View post →
Nutri Emi
@nutriarebelde · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 4,149 followers View post →
Observadora007
@observadora007 · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 1,580 followers View post →
Xavier León
@xleonaguilera · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 252 followers View post →
Carlos Sanchez
@carlosjsanchezm · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 2,933 followers View post →
Ariana Cabrera
@ArianaC69667903 · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 70 followers View post →
LP
@Lkfpaez · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 1,382 followers View post →
Félix Sierra
@fef_sierra · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 353 followers View post →
@guillodoc
@guillodoc · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 324 followers View post →
Dr. Suzana Mantovani
@Tweet_Nutrition · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 4,580 followers View post →
Aleck Zar ☘️
@aleck2000 · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 218 followers View post →
Oscar Andres
@OscarAndresMD · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 551 followers View post →
Adriana Farías Ruiz
@afariasr3 · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 661 followers View post →
Teresa Sánchez
@LaSevi6 · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 814 followers View post →
Armando Ribeiro
@Armando_Ribeiro · X

Antibiotics and #mentalhealth: The good, the bad and the ugly https://t.co/BgzbwEvp3N

Nov 29, 2022 · 1 like · 5,048 followers View post →
-Pao ✨
@paiiomr · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 3 followers View post →
Armando Ribeiro
@Armando_Ribeiro · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 5,048 followers View post →
Maria
@marmar7319 · X

RT @IberianCitizen: Antibióticos y salud mental

Nov 29, 2022 · 59 shares · 1,012 followers View post →
IberianCitizen
@IberianCitizen · X

Antibióticos y salud mental

Nov 29, 2022 · 149 likes · 59 shares · 12,931 followers View post →
JIM - Journal of Internal Medicine
@JInternMed · X

RT @ZoeZhan14710001:

Nov 29, 2022 · 1 share · 1,640 followers View post →
Microbiome Research Reports
@MicroResRep · X

Nov 23, 2022 · 1 like · 1 share · 1,134 followers View post →
Elliot Skirrow
@ElliotSkirrow · X

@virtuallysoph @parajon82 @drchatterjeeuk @DrZachBush fell down a rabbit hole trying to find a paper. Best I can is this, which is an interesting read (fine I skimmed it so far). Key point I saw was use in adolescence (mice) has a lasting affect into adulthood. https://t.co/B9yvdAHQQp

Oct 3, 2022 · 53 followers View post →
JIM - Journal of Internal Medicine
@JInternMed · X

New review! #Antibiotics and mental health: The good, the bad and the ugly @TedDinan #gutmicrobiota #gutbrainaxis #depression https://t.co/3TopUDlAYS https://t.co/d5VpekdPzs

Jul 14, 2022 · 1,640 followers View post →
Symbiosis papers
@Symbiosispapers · X

Antibiotics and mental health: The good, the bad and the ugly https://t.co/nT9EoRi2u3

Jul 12, 2022 · 1,113 followers View post →